PIGF (phosphatidylinositol glycan anchor biosynthesis class F) - Rat Genome Database

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Gene: PIGF (phosphatidylinositol glycan anchor biosynthesis class F) Homo sapiens
Analyze
Symbol: PIGF
Name: phosphatidylinositol glycan anchor biosynthesis class F
RGD ID: 1351645
HGNC Page HGNC
Description: Predicted to have mannose-ethanolamine phosphotransferase activity. Predicted to be involved in GPI anchor biosynthetic process. Predicted to localize to endoplasmic reticulum membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: GPI11 homolog; MGC32646; MGC33136; phosphatidylinositol glycan anchor biosynthesis, class F; phosphatidylinositol glycan, class f; phosphatidylinositol-glycan biosynthesis class F protein; PIG-F
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Related Pseudogenes: PIGFP1   PIGFP2   PIGFP3  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
NCBI Annotation Information: Note: PGF (Gene ID: 5228) and PIGF (Gene ID: 5281) share the PIGF symbol/alias in common. PIGF is a widely used alternative gene symbol for placental growth factor (PGF), which can be confused with the official symbol for phosphatidylinositol glycan anchor biosynthesis class F (PIGF). [06 Jul 2018]
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl246,580,937 - 46,617,055 (-)EnsemblGRCh38hg38GRCh38
GRCh38246,580,937 - 46,617,057 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37246,808,076 - 46,844,180 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36246,661,917 - 46,697,755 (-)NCBINCBI36hg18NCBI36
Build 34246,720,066 - 46,755,855NCBI
Celera246,647,088 - 46,682,932 (-)NCBI
Cytogenetic Map2p21NCBI
HuRef246,545,829 - 46,581,678 (-)NCBIHuRef
CHM1_1246,738,704 - 46,774,545 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:8081220   PMID:8463218   PMID:8575782   PMID:10781593   PMID:11102867   PMID:12477932   PMID:15489334   PMID:15632136   PMID:20416077   PMID:20966902   PMID:21873635   PMID:23333304  
PMID:24921169   PMID:25074286   PMID:28963486   PMID:29987050   PMID:30173595   PMID:30831776   PMID:32296183  


Genomics

Comparative Map Data
PIGF
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl246,580,937 - 46,617,055 (-)EnsemblGRCh38hg38GRCh38
GRCh38246,580,937 - 46,617,057 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37246,808,076 - 46,844,180 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36246,661,917 - 46,697,755 (-)NCBINCBI36hg18NCBI36
Build 34246,720,066 - 46,755,855NCBI
Celera246,647,088 - 46,682,932 (-)NCBI
Cytogenetic Map2p21NCBI
HuRef246,545,829 - 46,581,678 (-)NCBIHuRef
CHM1_1246,738,704 - 46,774,545 (-)NCBICHM1_1
Pigf
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391787,304,684 - 87,332,975 (-)NCBIGRCm39mm39
GRCm39 Ensembl1787,304,684 - 87,332,834 (-)Ensembl
GRCm381786,997,259 - 87,025,401 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1786,997,256 - 87,025,406 (-)EnsemblGRCm38mm10GRCm38
MGSCv371787,396,599 - 87,424,741 (-)NCBIGRCm37mm9NCBIm37
MGSCv361786,905,585 - 86,933,727 (-)NCBImm8
Celera1791,376,256 - 91,402,912 (-)NCBICelera
Cytogenetic Map17E4NCBI
cM Map1756.9NCBI
Pigf
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.267,589,528 - 7,617,721 (+)NCBI
Rnor_6.0 Ensembl610,568,614 - 10,592,454 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0610,565,841 - 10,593,972 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0620,554,358 - 20,582,471 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4610,446,734 - 10,474,805 (-)NCBIRGSC3.4rn4RGSC3.4
Celera67,325,024 - 7,353,152 (+)NCBICelera
Cytogenetic Map6q12NCBI
Pigf
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495544113,492,334 - 13,525,581 (-)NCBIChiLan1.0ChiLan1.0
PIGF
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12A47,627,376 - 47,663,272 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A47,627,376 - 47,663,272 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02A46,696,543 - 46,732,625 (-)NCBIMhudiblu_PPA_v0panPan3
PIGF
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11048,804,226 - 48,840,188 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1048,718,482 - 48,840,074 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1048,658,441 - 48,694,179 (-)NCBI
ROS_Cfam_1.01049,675,215 - 49,711,194 (-)NCBI
UMICH_Zoey_3.11049,383,207 - 49,419,084 (-)NCBI
UNSW_CanFamBas_1.01049,673,490 - 49,709,226 (-)NCBI
UU_Cfam_GSD_1.01049,856,593 - 49,892,361 (-)NCBI
Pigf
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629234,159,334 - 34,266,826 (+)NCBI
SpeTri2.0NW_0049365085,659,059 - 5,695,441 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PIGF
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl393,925,881 - 93,973,528 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1393,925,886 - 93,973,531 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.23100,009,993 - 100,057,923 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PIGF
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11460,573,240 - 60,608,796 (+)NCBI
ChlSab1.1 Ensembl1460,572,815 - 60,611,085 (+)Ensembl
Pigf
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473828,031,839 - 28,069,409 (-)NCBI

Position Markers
D2S2603  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37246,810,045 - 46,810,220UniSTSGRCh37
Build 36246,663,549 - 46,663,724RGDNCBI36
Celera246,648,720 - 46,648,895RGD
Cytogenetic Map2p21UniSTS
Cytogenetic Map2p21-p16UniSTS
HuRef246,547,461 - 46,547,636UniSTS
Whitehead-YAC Contig Map2 UniSTS
RH92629  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37246,815,265 - 46,815,440UniSTSGRCh37
Build 36246,668,769 - 46,668,944RGDNCBI36
Celera246,653,940 - 46,654,115RGD
Cytogenetic Map2p21-p16UniSTS
HuRef246,552,680 - 46,552,855UniSTS
GeneMap99-GB4 RH Map2142.44UniSTS
G62001  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37246,809,213 - 46,809,338UniSTSGRCh37
Build 36246,662,717 - 46,662,842RGDNCBI36
Celera246,647,888 - 46,648,013RGD
Cytogenetic Map2p21UniSTS
Cytogenetic Map2p21-p16UniSTS
HuRef246,546,629 - 46,546,754UniSTS
G31523  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37246,828,104 - 46,828,272UniSTSGRCh37
Build 36246,681,608 - 46,681,776RGDNCBI36
Celera246,666,783 - 46,666,951RGD
Cytogenetic Map2p21-p16UniSTS
HuRef246,565,524 - 46,565,692UniSTS
SHGC-64130  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37246,825,809 - 46,825,912UniSTSGRCh37
Build 36246,679,313 - 46,679,416RGDNCBI36
Celera246,664,488 - 46,664,591RGD
Cytogenetic Map2p21-p16UniSTS
HuRef246,563,229 - 46,563,332UniSTS
TNG Radiation Hybrid Map210032.0UniSTS
SHGC-32727  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37246,809,397 - 46,809,549UniSTSGRCh37
GRCh372130,969,135 - 130,969,278UniSTSGRCh37
Build 362130,685,605 - 130,685,748RGDNCBI36
Celera246,648,072 - 46,648,224RGD
Cytogenetic Map2q21.1UniSTS
Cytogenetic Map2p21-p16UniSTS
Cytogenetic Map2p21UniSTS
HuRef246,546,813 - 46,546,965UniSTS
TNG Radiation Hybrid Map565437.0UniSTS
GeneMap99-GB4 RH Map2142.44UniSTS
Whitehead-RH Map2202.4UniSTS
NCBI RH Map2291.6UniSTS
GeneMap99-G3 RH Map21972.0UniSTS
WI-7257  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map2p21UniSTS
Cytogenetic Map2p21-p16UniSTS
Whitehead-YAC Contig Map2 UniSTS
D14S659E  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map2p21UniSTS
Cytogenetic Map2p21-p16UniSTS

miRNA Target Status

Confirmed Target Of
miRNA GeneMature miRNAMethod NameResult TypeData TypeSupport TypePMID
MIR125B1hsa-miR-125b-5pMirtarbaseexternal_infoLuciferase reporter assay//qRT-PCR//Western blotFunctional MTI21703189
MIR125B2hsa-miR-125b-5pMirtarbaseexternal_infoLuciferase reporter assay//qRT-PCR//Western blotFunctional MTI21703189

Predicted Target Of
Summary Value
Count of predictions:808
Count of miRNA genes:426
Interacting mature miRNAs:462
Transcripts:ENST00000281382, ENST00000306465, ENST00000412717, ENST00000420164, ENST00000474980, ENST00000482786, ENST00000495933
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 93 7 88 22 277 24 195 42 117 43 285 183 5 1 1 17 3 2
Low 2346 2779 1636 601 1501 440 4162 2125 3616 372 1175 1429 169 1203 2771 3
Below cutoff 205 2 1 173 1 30 1 4 1

Sequence


Reference Sequences
RefSeq Acc Id: ENST00000281382   ⟹   ENSP00000281382
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl246,580,937 - 46,617,041 (-)Ensembl
RefSeq Acc Id: ENST00000306465   ⟹   ENSP00000302663
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl246,581,285 - 46,617,051 (-)Ensembl
RefSeq Acc Id: ENST00000412717   ⟹   ENSP00000413202
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl246,581,416 - 46,617,055 (-)Ensembl
RefSeq Acc Id: ENST00000420164   ⟹   ENSP00000410361
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl246,581,285 - 46,612,274 (-)Ensembl
RefSeq Acc Id: ENST00000474980   ⟹   ENSP00000429355
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl246,615,018 - 46,617,037 (-)Ensembl
RefSeq Acc Id: ENST00000482786
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl246,581,285 - 46,588,622 (-)Ensembl
RefSeq Acc Id: ENST00000495933
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl246,612,228 - 46,617,030 (-)Ensembl
RefSeq Acc Id: NM_002643   ⟹   NP_002634
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38246,580,937 - 46,617,041 (-)NCBI
GRCh37246,808,413 - 46,844,251 (-)NCBI
Build 36246,661,917 - 46,697,755 (-)NCBI Archive
HuRef246,545,829 - 46,581,678 (-)ENTREZGENE
CHM1_1246,738,704 - 46,774,545 (-)NCBI
Sequence:
RefSeq Acc Id: NM_173074   ⟹   NP_775097
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38246,580,937 - 46,617,041 (-)NCBI
GRCh37246,808,413 - 46,844,251 (-)ENTREZGENE
Build 36246,661,917 - 46,697,755 (-)NCBI Archive
HuRef246,545,829 - 46,581,678 (-)ENTREZGENE
CHM1_1246,738,704 - 46,774,545 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005264369   ⟹   XP_005264426
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38246,591,803 - 46,617,057 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011532908   ⟹   XP_011531210
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38246,581,274 - 46,617,057 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_002634   ⟸   NM_002643
- Peptide Label: isoform 1
- UniProtKB: Q07326 (UniProtKB/Swiss-Prot),   Q6IB04 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_775097   ⟸   NM_173074
- Peptide Label: isoform 2
- UniProtKB: Q07326 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_005264426   ⟸   XM_005264369
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_011531210   ⟸   XM_011532908
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSP00000302663   ⟸   ENST00000306465
RefSeq Acc Id: ENSP00000413202   ⟸   ENST00000412717
RefSeq Acc Id: ENSP00000281382   ⟸   ENST00000281382
RefSeq Acc Id: ENSP00000410361   ⟸   ENST00000420164
RefSeq Acc Id: ENSP00000429355   ⟸   ENST00000474980

Promoters
RGD ID:6860234
Promoter ID:EPDNEW_H3282
Type:initiation region
Name:PIGF_1
Description:phosphatidylinositol glycan anchor biosynthesis class F
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38246,617,039 - 46,617,099EPDNEW
RGD ID:6797946
Promoter ID:HG_KWN:32520
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Lymphoblastoid
Transcripts:OTTHUMT00000329341
Position:
Human AssemblyChrPosition (strand)Source
Build 36246,668,471 - 46,668,971 (-)MPROMDB
RGD ID:6797944
Promoter ID:HG_KWN:32522
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   K562,   Lymphoblastoid,   NB4
Transcripts:NM_173074,   OTTHUMT00000250749,   OTTHUMT00000329339,   OTTHUMT00000329340,   OTTHUMT00000329342
Position:
Human AssemblyChrPosition (strand)Source
Build 36246,697,401 - 46,697,901 (-)MPROMDB

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 2p25.3-16.1(chr2:66097-55570637)x3 copy number gain See cases [RCV000052933] Chr2:66097..55570637 [GRCh38]
Chr2:66097..55797773 [GRCh37]
Chr2:56097..55651277 [NCBI36]
Chr2:2p25.3-16.1
pathogenic
GRCh38/hg38 2p22.1-16.1(chr2:40738282-57863821)x3 copy number gain See cases [RCV000052943] Chr2:40738282..57863821 [GRCh38]
Chr2:40965422..58090956 [GRCh37]
Chr2:40818926..57944460 [NCBI36]
Chr2:2p22.1-16.1
pathogenic
GRCh38/hg38 2p21(chr2:46592232-47488001)x3 copy number gain See cases [RCV000137575] Chr2:46592232..47488001 [GRCh38]
Chr2:46819371..47715140 [GRCh37]
Chr2:46672875..47568644 [NCBI36]
Chr2:2p21
likely benign
GRCh38/hg38 2p21-16.3(chr2:46415109-48203207)x3 copy number gain See cases [RCV000141883] Chr2:46415109..48203207 [GRCh38]
Chr2:46642248..48430346 [GRCh37]
Chr2:46495752..48283850 [NCBI36]
Chr2:2p21-16.3
uncertain significance
GRCh38/hg38 2p25.1-11.2(chr2:7495123-87705899)x3 copy number gain See cases [RCV000141494] Chr2:7495123..87705899 [GRCh38]
Chr2:7635254..88005418 [GRCh37]
Chr2:7552705..87786533 [NCBI36]
Chr2:2p25.1-11.2
benign
GRCh38/hg38 2p21(chr2:46573689-46732838)x3 copy number gain See cases [RCV000142598] Chr2:46573689..46732838 [GRCh38]
Chr2:46800828..46959977 [GRCh37]
Chr2:46654332..46813481 [NCBI36]
Chr2:2p21
benign
NM_014171.6(CRIPT):c.0_17-582del deletion Short stature with microcephaly and distinctive facies [RCV000240818] Chr2:46616861..46618191 [GRCh38]
Chr2:46844000..46845330 [GRCh37]
Chr2:2p21
pathogenic
GRCh37/hg19 2p25.3-q37.3(chr2:14238-243048760)x3 copy number gain not provided [RCV000752802] Chr2:14238..243048760 [GRCh37]
Chr2:2p25.3-q37.3
pathogenic
GRCh37/hg19 2p23.3-16.1(chr2:27861707-60790985)x3 copy number gain See cases [RCV000454271] Chr2:27861707..60790985 [GRCh37]
Chr2:2p23.3-16.1
pathogenic
GRCh37/hg19 2p25.3-q37.3(chr2:12771-242783384) copy number gain See cases [RCV000512056] Chr2:12771..242783384 [GRCh37]
Chr2:2p25.3-q37.3
pathogenic
NC_000002.11:g.38121110_47669522inv inversion Lynch syndrome [RCV000494356] Chr2:38121110..47669522 [GRCh37]
Chr2:2p22.2-21
pathogenic
GRCh37/hg19 2p25.3-q37.3(chr2:12771-242783384)x3 copy number gain See cases [RCV000511212] Chr2:12771..242783384 [GRCh37]
Chr2:2p25.3-q37.3
pathogenic
GRCh37/hg19 2p22.3-16.1(chr2:34792916-56676541)x3 copy number gain not provided [RCV000682169] Chr2:34792916..56676541 [GRCh37]
Chr2:2p22.3-16.1
pathogenic
GRCh37/hg19 2p21(chr2:46557702-47744377)x3 copy number gain not provided [RCV000682119] Chr2:46557702..47744377 [GRCh37]
Chr2:2p21
uncertain significance
Single allele inversion not provided [RCV000714264] Chr2:40608411..146900718 [GRCh37]
Chr2:2p22.1-q22.3
likely pathogenic
GRCh37/hg19 2p25.3-q37.3(chr2:15672-243101834)x3 copy number gain not provided [RCV000752804] Chr2:15672..243101834 [GRCh37]
Chr2:2p25.3-q37.3
pathogenic
GRCh37/hg19 2p24.1-16.3(chr2:22665048-52850368)x3 copy number gain not provided [RCV000752875] Chr2:22665048..52850368 [GRCh37]
Chr2:2p24.1-16.3
pathogenic
NC_000002.11:g.46844000_46845330del1331 deletion Short stature with microcephaly and distinctive facies [RCV000736018] Chr2:46844000..46845330 [GRCh37]
Chr2:2p21
pathogenic
NM_002643.4(PIGF):c.185T>C (p.Val62Ala) single nucleotide variant not provided [RCV000958501] Chr2:46614980 [GRCh38]
Chr2:46842119 [GRCh37]
Chr2:2p21
benign
GRCh37/hg19 2p21(chr2:46179259-47646894)x3 copy number gain not provided [RCV001005255] Chr2:46179259..47646894 [GRCh37]
Chr2:2p21
uncertain significance

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:8962 AgrOrtholog
COSMIC PIGF COSMIC
Ensembl Genes ENSG00000151665 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSP00000281382 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000302663 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000410361 UniProtKB/TrEMBL
  ENSP00000413202 UniProtKB/TrEMBL
  ENSP00000429355 UniProtKB/TrEMBL
Ensembl Transcript ENST00000281382 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000306465 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000412717 UniProtKB/TrEMBL
  ENST00000420164 UniProtKB/TrEMBL
  ENST00000474980 UniProtKB/TrEMBL
GTEx ENSG00000151665 GTEx
HGNC ID HGNC:8962 ENTREZGENE
Human Proteome Map PIGF Human Proteome Map
InterPro GPI_biosynthesis_protein_Pig-F UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:5281 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 5281 ENTREZGENE
OMIM 600153 OMIM
Pfam PIG-F UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA33293 PharmGKB
UniProt E5RIN5_HUMAN UniProtKB/TrEMBL
  F8WEN5_HUMAN UniProtKB/TrEMBL
  H7C392_HUMAN UniProtKB/TrEMBL
  PIGF_HUMAN UniProtKB/Swiss-Prot, ENTREZGENE
  Q6IB04 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary Q8WW20 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-11-10 PIGF  phosphatidylinositol glycan anchor biosynthesis class F    phosphatidylinositol glycan anchor biosynthesis, class F  Symbol and/or name change 5135510 APPROVED
2011-08-17 PIGF  phosphatidylinositol glycan anchor biosynthesis, class F  PIGF  phosphatidylinositol glycan anchor biosynthesis, class F  Symbol and/or name change 5135510 APPROVED