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Gene: CD6 (CD6 molecule) Homo sapiens
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Symbol: CD6
Name: CD6 molecule
Description: This gene encodes a protein found on the outer membrane of T-lymphocytes as well as some other immune cells. The encoded protein contains three scavenger receptor cysteine-rich (SRCR) domains and a binding site for an activated leukocyte cell adhesion molecule. The gene product is important for continuation of T cell activation. This gene may be associated with susceptibility to multiple sclerosis (PMID: 19525953, 21849685). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: CD6 antigen; FLJ44171; T-cell differentiation antigen CD6; T12; TP120
Orthologs:
Mus musculus (house mouse) : Cd6 (CD6 antigen)  MGI  Alliance
Rattus norvegicus (Norway rat) : Cd6 (Cd6 molecule)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cd6 (CD6 molecule)
Pan paniscus (bonobo/pygmy chimpanzee) : CD6 (CD6 molecule)
Canis lupus familiaris (dog) : CD6 (CD6 molecule)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cd6 (CD6 molecule)
Sus scrofa (pig) : CD6 (CD6 molecule)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381160,971,641 - 61,020,377 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371160,739,113 - 60,787,849 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361160,495,750 - 60,544,425 (+)NCBINCBI36hg18NCBI36
Build 341160,495,749 - 60,544,422NCBI
Celera1158,099,987 - 58,148,914 (+)NCBI
Cytogenetic Map11q12.2NCBI
HuRef1157,085,244 - 57,134,039 (+)NCBIHuRef
CHM1_11160,605,326 - 60,654,240 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on CD6
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1351600
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-06-18
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.