CD6 (CD6 molecule) - Rat Genome Database

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Gene: CD6 (CD6 molecule) Homo sapiens
Analyze
Symbol: CD6
Name: CD6 molecule
RGD ID: 1351600
HGNC Page HGNC:1691
Description: Enables identical protein binding activity; lipopolysaccharide binding activity; and lipoteichoic acid binding activity. Involved in several processes, including heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules; lipopolysaccharide-mediated signaling pathway; and positive regulation of cytokine production involved in inflammatory response. Located in T cell receptor complex and immunological synapse.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: CD6 antigen; FLJ44171; T-cell differentiation antigen CD6; T12; TP120
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381160,971,680 - 61,020,377 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1160,971,680 - 61,020,377 (+)EnsemblGRCh38hg38GRCh38
GRCh371160,739,152 - 60,787,849 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361160,495,750 - 60,544,425 (+)NCBINCBI36Build 36hg18NCBI36
Build 341160,495,749 - 60,544,422NCBI
Celera1158,099,987 - 58,148,914 (+)NCBICelera
Cytogenetic Map11q12.2NCBI
HuRef1157,085,244 - 57,134,039 (+)NCBIHuRef
CHM1_11160,605,326 - 60,654,240 (+)NCBICHM1_1
T2T-CHM13v2.01160,922,811 - 60,971,572 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
References

References - curated
# Reference Title Reference Citation
1. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:1919444   PMID:2016320   PMID:3923629   PMID:7543097   PMID:7589069   PMID:7678115   PMID:9013954   PMID:9394826   PMID:9436462   PMID:10899308   PMID:12473675   PMID:12477932  
PMID:12493773   PMID:15294938   PMID:16034076   PMID:16344560   PMID:16352806   PMID:16818742   PMID:16818773   PMID:16914752   PMID:17371992   PMID:17601777   PMID:18707547   PMID:19525953  
PMID:19865102   PMID:19879194   PMID:20237496   PMID:20430450   PMID:20726988   PMID:20810246   PMID:21145461   PMID:21178331   PMID:21244703   PMID:21552549   PMID:21833088   PMID:21849685  
PMID:21873635   PMID:21956609   PMID:21988832   PMID:22685579   PMID:22994200   PMID:23128233   PMID:23638056   PMID:23711376   PMID:24130718   PMID:24584089   PMID:24890719   PMID:24945728  
PMID:25088497   PMID:25777272   PMID:26028048   PMID:26146185   PMID:26302795   PMID:26844569   PMID:27108704   PMID:27896837   PMID:28209777   PMID:28289074   PMID:29225340   PMID:30395204  
PMID:32307907   PMID:33913383   PMID:33961781   PMID:34070159   PMID:34981775   PMID:35487454   PMID:35767366   PMID:38139340   PMID:38280067  


Genomics

Comparative Map Data
CD6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381160,971,680 - 61,020,377 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1160,971,680 - 61,020,377 (+)EnsemblGRCh38hg38GRCh38
GRCh371160,739,152 - 60,787,849 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361160,495,750 - 60,544,425 (+)NCBINCBI36Build 36hg18NCBI36
Build 341160,495,749 - 60,544,422NCBI
Celera1158,099,987 - 58,148,914 (+)NCBICelera
Cytogenetic Map11q12.2NCBI
HuRef1157,085,244 - 57,134,039 (+)NCBIHuRef
CHM1_11160,605,326 - 60,654,240 (+)NCBICHM1_1
T2T-CHM13v2.01160,922,811 - 60,971,572 (+)NCBIT2T-CHM13v2.0
Cd6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391910,766,703 - 10,807,427 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1910,766,705 - 10,807,422 (-)EnsemblGRCm39 Ensembl
GRCm381910,789,339 - 10,830,062 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1910,789,341 - 10,830,058 (-)EnsemblGRCm38mm10GRCm38
MGSCv371910,863,829 - 10,904,548 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361910,856,386 - 10,897,098 (-)NCBIMGSCv36mm8
Celera1911,482,305 - 11,523,180 (-)NCBICelera
Cytogenetic Map19ANCBI
cM Map197.16NCBI
Cd6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81216,867,767 - 216,906,642 (-)NCBIGRCr8
mRatBN7.21207,442,873 - 207,481,703 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1207,442,877 - 207,481,634 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1215,817,721 - 215,856,474 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01222,876,916 - 222,915,651 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01215,572,103 - 215,610,862 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01226,848,399 - 226,887,259 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1226,848,403 - 226,887,156 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01233,913,073 - 233,951,869 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41213,290,835 - 213,329,594 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11213,449,267 - 213,487,963 (-)NCBI
Celera1204,934,769 - 204,973,456 (-)NCBICelera
Cytogenetic Map1q43NCBI
Cd6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049555115,592,176 - 5,617,421 (+)NCBIChiLan1.0ChiLan1.0
CD6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2962,140,849 - 62,189,584 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11163,219,722 - 63,233,664 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01156,269,585 - 56,283,516 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11159,691,762 - 59,723,974 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1159,675,221 - 59,722,916 (+)Ensemblpanpan1.1panPan2
CD6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11855,296,116 - 55,336,014 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1855,296,986 - 55,335,880 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1853,869,334 - 53,909,224 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01856,344,791 - 56,384,690 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1856,344,791 - 56,384,568 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11855,402,485 - 55,442,306 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01855,023,721 - 55,063,783 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01855,905,105 - 55,944,991 (-)NCBIUU_Cfam_GSD_1.0
Cd6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494711,818,710 - 11,829,849 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365811,932,668 - 1,969,126 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365811,932,596 - 1,943,671 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CD6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl210,738,471 - 10,785,516 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1210,739,560 - 10,785,548 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2210,240,961 - 10,329,820 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CD6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1112,827,238 - 12,878,304 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl112,828,285 - 12,877,704 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038110,196,562 - 110,245,906 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cd6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624926324,828 - 333,246 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624926325,327 - 333,405 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in CD6
28 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
Single allele deletion Intellectual disability [RCV001293382] Chr11:118359328..118372573 [GRCh37]
Chr11:11p15.3-q23.3		 pathogenic
GRCh37/hg19 11p15.5-q25(chr11:230616-134938470) copy number gain See cases [RCV000511729] Chr11:230616..134938470 [GRCh37]
Chr11:11p15.5-q25		 pathogenic
GRCh37/hg19 11p15.5-q25(chr11:230616-134938470)x3 copy number gain See cases [RCV000510881] Chr11:230616..134938470 [GRCh37]
Chr11:11p15.5-q25		 pathogenic
NM_006725.5(CD6):c.229C>A (p.Arg77Ser) single nucleotide variant Inborn genetic diseases [RCV003248925] Chr11:61007670 [GRCh38]
Chr11:60775142 [GRCh37]
Chr11:11q12.2		 uncertain significance
NM_006725.5(CD6):c.634C>T (p.Pro212Ser) single nucleotide variant Inborn genetic diseases [RCV003295153] Chr11:61008698 [GRCh38]
Chr11:60776170 [GRCh37]
Chr11:11q12.2		 uncertain significance
NM_006725.5(CD6):c.1706G>A (p.Gly569Glu) single nucleotide variant Inborn genetic diseases [RCV003295793] Chr11:61017882 [GRCh38]
Chr11:60785354 [GRCh37]
Chr11:11q12.2		 uncertain significance
GRCh37/hg19 11q12.1-12.3(chr11:58935215-62177656)x3 copy number gain not provided [RCV000683362] Chr11:58935215..62177656 [GRCh37]
Chr11:11q12.1-12.3		 likely pathogenic
GRCh37/hg19 11p15.5-q25(chr11:198510-134934063)x3 copy number gain not provided [RCV000737348] Chr11:198510..134934063 [GRCh37]
Chr11:11p15.5-q25		 pathogenic
GRCh37/hg19 11p15.5-q25(chr11:70864-134938470)x3 copy number gain not provided [RCV000749874] Chr11:70864..134938470 [GRCh37]
Chr11:11p15.5-q25		 pathogenic
GRCh37/hg19 11q12.2(chr11:60757633-60878915)x3 copy number gain not provided [RCV000737541] Chr11:60757633..60878915 [GRCh37]
Chr11:11q12.2		 benign
GRCh37/hg19 11q12.2(chr11:60760971-60872073)x3 copy number gain not provided [RCV000737542] Chr11:60760971..60872073 [GRCh37]
Chr11:11q12.2		 benign
NM_006725.5(CD6):c.1583-8T>C single nucleotide variant not provided [RCV000898728] Chr11:61017751 [GRCh38]
Chr11:60785223 [GRCh37]
Chr11:11q12.2		 benign
GRCh37/hg19 11q12.2(chr11:60499486-61529578)x3 copy number gain not provided [RCV000848682] Chr11:60499486..61529578 [GRCh37]
Chr11:11q12.2		 uncertain significance
GRCh37/hg19 11q12.2-12.3(chr11:60385382-62456278)x3 copy number gain not provided [RCV001006412] Chr11:60385382..62456278 [GRCh37]
Chr11:11q12.2-12.3		 uncertain significance
NC_000011.9:g.(?_59596957)_(68707199_?)dup duplication Familial temporal lobe epilepsy 8 [RCV001372442] Chr11:59596957..68707199 [GRCh37]
Chr11:11q12.1-13.3		 uncertain significance
NC_000011.9:g.(?_58916346)_(64972349_?)dup duplication Leukocyte adhesion deficiency 3 [RCV003113394]|not provided [RCV003113393] Chr11:58916346..64972349 [GRCh37]
Chr11:11q12.1-13.1		 uncertain significance|no classifications from unflagged records
GRCh37/hg19 11p11.2-q12.2(chr11:51581311-54891247)x3 copy number gain See cases [RCV002286338] Chr11:51581311..54891247 [GRCh37]
Chr11:11p11.2-q12.2		 pathogenic
GRCh37/hg19 11p13-q25(chr11:32799481-134938470)x3 copy number gain MISSED ABORTION [RCV002282973] Chr11:32799481..134938470 [GRCh37]
Chr11:11p13-q25		 pathogenic
NM_006725.5(CD6):c.1843C>A (p.Pro615Thr) single nucleotide variant Inborn genetic diseases [RCV002773514] Chr11:61018294 [GRCh38]
Chr11:60785766 [GRCh37]
Chr11:11q12.2		 uncertain significance
NM_006725.5(CD6):c.1200G>A (p.Met400Ile) single nucleotide variant Inborn genetic diseases [RCV002753719] Chr11:61013472 [GRCh38]
Chr11:60780944 [GRCh37]
Chr11:11q12.2		 uncertain significance
NM_006725.5(CD6):c.65C>A (p.Ala22Asp) single nucleotide variant Inborn genetic diseases [RCV002734754] Chr11:61006589 [GRCh38]
Chr11:60774061 [GRCh37]
Chr11:11q12.2		 uncertain significance
NM_006725.5(CD6):c.1412A>G (p.Gln471Arg) single nucleotide variant Inborn genetic diseases [RCV002865023] Chr11:61015737 [GRCh38]
Chr11:60783209 [GRCh37]
Chr11:11q12.2		 uncertain significance
NM_006725.5(CD6):c.1939C>G (p.Pro647Ala) single nucleotide variant Inborn genetic diseases [RCV002969704] Chr11:61018390 [GRCh38]
Chr11:60785862 [GRCh37]
Chr11:11q12.2		 uncertain significance
NM_006725.5(CD6):c.1226G>T (p.Gly409Val) single nucleotide variant Inborn genetic diseases [RCV002868718] Chr11:61013498 [GRCh38]
Chr11:60780970 [GRCh37]
Chr11:11q12.2		 uncertain significance
NM_006725.5(CD6):c.1673C>A (p.Pro558Gln) single nucleotide variant Inborn genetic diseases [RCV002782979] Chr11:61017849 [GRCh38]
Chr11:60785321 [GRCh37]
Chr11:11q12.2		 uncertain significance
NM_006725.5(CD6):c.947A>G (p.Lys316Arg) single nucleotide variant Inborn genetic diseases [RCV003000631] Chr11:61009737 [GRCh38]
Chr11:60777209 [GRCh37]
Chr11:11q12.2		 uncertain significance
NM_006725.5(CD6):c.786C>A (p.His262Gln) single nucleotide variant Inborn genetic diseases [RCV002949800] Chr11:61009576 [GRCh38]
Chr11:60777048 [GRCh37]
Chr11:11q12.2		 uncertain significance
NM_006725.5(CD6):c.977T>C (p.Met326Thr) single nucleotide variant Inborn genetic diseases [RCV002869386] Chr11:61009767 [GRCh38]
Chr11:60777239 [GRCh37]
Chr11:11q12.2		 uncertain significance
NM_006725.5(CD6):c.932C>A (p.Ala311Glu) single nucleotide variant Inborn genetic diseases [RCV002916136] Chr11:61009722 [GRCh38]
Chr11:60777194 [GRCh37]
Chr11:11q12.2		 uncertain significance
NM_006725.5(CD6):c.943C>A (p.Pro315Thr) single nucleotide variant Inborn genetic diseases [RCV002855857] Chr11:61009733 [GRCh38]
Chr11:60777205 [GRCh37]
Chr11:11q12.2		 uncertain significance
NM_006725.5(CD6):c.1691C>T (p.Ser564Leu) single nucleotide variant Inborn genetic diseases [RCV002961735] Chr11:61017867 [GRCh38]
Chr11:60785339 [GRCh37]
Chr11:11q12.2		 uncertain significance
NM_006725.5(CD6):c.316C>G (p.Pro106Ala) single nucleotide variant Inborn genetic diseases [RCV002679531] Chr11:61007757 [GRCh38]
Chr11:60775229 [GRCh37]
Chr11:11q12.2		 uncertain significance
NM_006725.5(CD6):c.1426G>A (p.Glu476Lys) single nucleotide variant Inborn genetic diseases [RCV003212127] Chr11:61015751 [GRCh38]
Chr11:60783223 [GRCh37]
Chr11:11q12.2		 uncertain significance
NM_006725.5(CD6):c.1219G>C (p.Val407Leu) single nucleotide variant Inborn genetic diseases [RCV003192081] Chr11:61013491 [GRCh38]
Chr11:60780963 [GRCh37]
Chr11:11q12.2		 uncertain significance
NM_006725.5(CD6):c.1822C>A (p.Gln608Lys) single nucleotide variant Inborn genetic diseases [RCV003211052] Chr11:61017998 [GRCh38]
Chr11:60785470 [GRCh37]
Chr11:11q12.2		 uncertain significance
NM_006725.5(CD6):c.1841G>A (p.Gly614Glu) single nucleotide variant Inborn genetic diseases [RCV003356738] Chr11:61018292 [GRCh38]
Chr11:60785764 [GRCh37]
Chr11:11q12.2		 uncertain significance
NM_006725.5(CD6):c.983A>T (p.Tyr328Phe) single nucleotide variant Inborn genetic diseases [RCV003359616] Chr11:61009773 [GRCh38]
Chr11:60777245 [GRCh37]
Chr11:11q12.2		 uncertain significance
NM_006725.5(CD6):c.314C>G (p.Pro105Arg) single nucleotide variant Inborn genetic diseases [RCV003376109] Chr11:61007755 [GRCh38]
Chr11:60775227 [GRCh37]
Chr11:11q12.2		 uncertain significance
GRCh37/hg19 11q12.2-13.5(chr11:59923608-76272324)x3 copy number gain not provided [RCV003484842] Chr11:59923608..76272324 [GRCh37]
Chr11:11q12.2-13.5		 pathogenic
GRCh37/hg19 11p11.12-q13.1(chr11:50398499-63924462)x3 copy number gain not specified [RCV003986918] Chr11:50398499..63924462 [GRCh37]
Chr11:11p11.12-q13.1		 likely pathogenic
GRCh37/hg19 11q12.1-13.3(chr11:56895955-69295402)x3 copy number gain not specified [RCV003986944] Chr11:56895955..69295402 [GRCh37]
Chr11:11q12.1-13.3		 likely pathogenic
NM_006725.5(CD6):c.650C>T (p.Thr217Met) single nucleotide variant CD6-related condition [RCV003976655] Chr11:61008714 [GRCh38]
Chr11:60776186 [GRCh37]
Chr11:11q12.2		 benign
NM_006725.5(CD6):c.1875C>G (p.Ser625=) single nucleotide variant CD6-related condition [RCV003907373] Chr11:61018326 [GRCh38]
Chr11:60785798 [GRCh37]
Chr11:11q12.2		 benign
NM_006725.5(CD6):c.771G>C (p.Ala257=) single nucleotide variant CD6-related condition [RCV003974666] Chr11:61008835 [GRCh38]
Chr11:60776307 [GRCh37]
Chr11:11q12.2		 benign
NM_006725.5(CD6):c.1299C>T (p.Pro433=) single nucleotide variant CD6-related condition [RCV003974228] Chr11:61013926 [GRCh38]
Chr11:60781398 [GRCh37]
Chr11:11q12.2		 likely benign
NM_006725.5(CD6):c.1816G>A (p.Gly606Ser) single nucleotide variant CD6-related condition [RCV003976532] Chr11:61017992 [GRCh38]
Chr11:60785464 [GRCh37]
Chr11:11q12.2		 benign
NM_006725.5(CD6):c.673C>T (p.Arg225Trp) single nucleotide variant CD6-related condition [RCV003977398] Chr11:61008737 [GRCh38]
Chr11:60776209 [GRCh37]
Chr11:11q12.2		 benign
NM_006725.5(CD6):c.1971C>T (p.Thr657=) single nucleotide variant CD6-related condition [RCV003931732] Chr11:61019282 [GRCh38]
Chr11:60786754 [GRCh37]
Chr11:11q12.2		 likely benign
NM_006725.5(CD6):c.1362G>A (p.Pro454=) single nucleotide variant CD6-related condition [RCV003932318] Chr11:61013989 [GRCh38]
Chr11:60781461 [GRCh37]
Chr11:11q12.2		 likely benign
NM_006725.5(CD6):c.1815C>T (p.Ala605=) single nucleotide variant CD6-related condition [RCV003967394] Chr11:61017991 [GRCh38]
Chr11:60785463 [GRCh37]
Chr11:11q12.2		 benign
NM_006725.5(CD6):c.49+8C>T single nucleotide variant CD6-related condition [RCV003916969] Chr11:60971922 [GRCh38]
Chr11:60739394 [GRCh37]
Chr11:11q12.2		 benign
NM_006725.5(CD6):c.770C>T (p.Ala257Val) single nucleotide variant CD6-related condition [RCV003974507] Chr11:61008834 [GRCh38]
Chr11:60776306 [GRCh37]
Chr11:11q12.2		 benign
NM_006725.5(CD6):c.567T>C (p.Thr189=) single nucleotide variant CD6-related condition [RCV003974628] Chr11:61008631 [GRCh38]
Chr11:60776103 [GRCh37]
Chr11:11q12.2		 benign
NM_006725.5(CD6):c.811G>A (p.Ala271Thr) single nucleotide variant CD6-related condition [RCV003977381] Chr11:61009601 [GRCh38]
Chr11:60777073 [GRCh37]
Chr11:11q12.2		 benign
NM_006725.5(CD6):c.1704A>G (p.Ser568=) single nucleotide variant CD6-related condition [RCV003974425] Chr11:61017880 [GRCh38]
Chr11:60785352 [GRCh37]
Chr11:11q12.2		 benign
NM_006725.5(CD6):c.1834T>C (p.Ser612Pro) single nucleotide variant CD6-related condition [RCV003921885] Chr11:61018010 [GRCh38]
Chr11:60785482 [GRCh37]
Chr11:11q12.2		 likely benign
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:6897
Count of miRNA genes:1087
Interacting mature miRNAs:1378
Transcripts:ENST00000313421, ENST00000344028, ENST00000344931, ENST00000346437, ENST00000352009, ENST00000419282, ENST00000433107, ENST00000452451, ENST00000505761, ENST00000538288, ENST00000538611, ENST00000541964, ENST00000542157, ENST00000542254, ENST00000545105, ENST00000545320
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
D11S1765  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371160,778,544 - 60,778,777UniSTSGRCh37
Build 361160,535,120 - 60,535,353RGDNCBI36
Celera1158,139,595 - 58,139,842RGD
Cytogenetic Map11q13UniSTS
Marshfield Genetic Map1161.78UniSTS
Marshfield Genetic Map1161.78RGD
Genethon Genetic Map1165.0UniSTS
TNG Radiation Hybrid Map1126764.0UniSTS
deCODE Assembly Map1165.93UniSTS
GeneMap99-GB4 RH Map11225.4UniSTS
Whitehead-RH Map11298.7UniSTS
Whitehead-YAC Contig Map11 UniSTS
RH70609  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371160,786,831 - 60,786,968UniSTSGRCh37
Build 361160,543,407 - 60,543,544RGDNCBI36
Celera1158,147,896 - 58,148,033RGD
Cytogenetic Map11q13UniSTS
HuRef1157,133,021 - 57,133,158UniSTS
GeneMap99-GB4 RH Map11225.4UniSTS
RH79917  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371160,786,828 - 60,787,038UniSTSGRCh37
Build 361160,543,404 - 60,543,614RGDNCBI36
Celera1158,147,893 - 58,148,103RGD
Cytogenetic Map11q13UniSTS
HuRef1157,133,018 - 57,133,228UniSTS
STS-X60992  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371160,787,352 - 60,787,558UniSTSGRCh37
Build 361160,543,928 - 60,544,134RGDNCBI36
Celera1158,148,417 - 58,148,623RGD
Cytogenetic Map11q13UniSTS
HuRef1157,133,542 - 57,133,748UniSTS
GeneMap99-GB4 RH Map11227.32UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 150 526 56 6 1019 5 9 1 8 32 244 13 3 1
Low 1368 1089 1291 492 773 334 2481 383 2093 262 1229 1170 164 1130 1300 2 1
Below cutoff 879 1363 356 111 81 110 1752 1763 1576 111 143 102 8 61 1471 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001254750 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001254751 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_006725 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_045638 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006718738 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006718739 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006718740 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006718741 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011545360 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011545362 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047427874 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047427875 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047427876 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047427877 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047427878 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047427879 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047427880 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047427881 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054370518 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054370519 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054370520 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054370521 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054370522 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054370523 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054370524 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054370525 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054370526 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054370527 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054370528 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054370529 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AH011243 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI657093 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK126159 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK128419 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK292704 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK312749 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AP003721 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC033755 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC078669 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471076 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068267 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DB147406 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DB155411 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ786329 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ786330 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KF455397 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U34623 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U34624 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U34625 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U66142 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U66143 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U66144 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U66145 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U66146 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X60992 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000313421   ⟹   ENSP00000323280
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1160,971,680 - 61,020,377 (+)Ensembl
RefSeq Acc Id: ENST00000344931   ⟹   ENSP00000340334
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1160,971,746 - 61,020,338 (+)Ensembl
RefSeq Acc Id: ENST00000352009   ⟹   ENSP00000340628
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1160,971,866 - 61,019,321 (+)Ensembl
RefSeq Acc Id: ENST00000419282
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1161,015,421 - 61,017,549 (+)Ensembl
RefSeq Acc Id: ENST00000433107   ⟹   ENSP00000410638
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1160,971,866 - 61,017,843 (+)Ensembl
RefSeq Acc Id: ENST00000452451   ⟹   ENSP00000390676
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1160,971,866 - 61,019,321 (+)Ensembl
RefSeq Acc Id: ENST00000505761
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1161,016,903 - 61,020,374 (+)Ensembl
RefSeq Acc Id: ENST00000538288
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1161,004,411 - 61,007,713 (+)Ensembl
RefSeq Acc Id: ENST00000538611   ⟹   ENSP00000443747
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1161,008,534 - 61,013,955 (+)Ensembl
RefSeq Acc Id: ENST00000541964
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1161,008,351 - 61,009,636 (+)Ensembl
RefSeq Acc Id: ENST00000542157   ⟹   ENSP00000440055
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1160,971,866 - 61,013,476 (+)Ensembl
RefSeq Acc Id: ENST00000542254   ⟹   ENSP00000443748
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1160,971,736 - 61,007,712 (+)Ensembl
RefSeq Acc Id: ENST00000545105
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1160,971,738 - 61,014,011 (+)Ensembl
RefSeq Acc Id: ENST00000545320
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1160,971,750 - 60,989,392 (+)Ensembl
RefSeq Acc Id: NM_001254750   ⟹   NP_001241679
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381160,971,680 - 61,020,377 (+)NCBI
GRCh371160,739,113 - 60,787,849 (+)NCBI
HuRef1157,085,244 - 57,134,039 (+)NCBI
CHM1_11160,605,326 - 60,654,240 (+)NCBI
T2T-CHM13v2.01160,922,811 - 60,971,572 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001254751   ⟹   NP_001241680
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381160,971,680 - 61,020,377 (+)NCBI
GRCh371160,739,113 - 60,787,849 (+)NCBI
HuRef1157,085,244 - 57,134,039 (+)NCBI
CHM1_11160,605,326 - 60,654,240 (+)NCBI
T2T-CHM13v2.01160,922,811 - 60,971,572 (+)NCBI
Sequence:
RefSeq Acc Id: NM_006725   ⟹   NP_006716
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381160,971,680 - 61,020,377 (+)NCBI
GRCh371160,739,113 - 60,787,849 (+)NCBI
Build 361160,495,750 - 60,544,425 (+)NCBI Archive
HuRef1157,085,244 - 57,134,039 (+)NCBI
CHM1_11160,605,326 - 60,654,240 (+)NCBI
T2T-CHM13v2.01160,922,811 - 60,971,572 (+)NCBI
Sequence:
RefSeq Acc Id: NR_045638
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381160,971,680 - 61,020,377 (+)NCBI
HuRef1157,085,244 - 57,134,039 (+)NCBI
CHM1_11160,605,326 - 60,654,240 (+)NCBI
T2T-CHM13v2.01160,922,811 - 60,971,572 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006718738   ⟹   XP_006718801
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381160,971,680 - 61,020,377 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006718739   ⟹   XP_006718802
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381160,971,680 - 61,020,377 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006718740   ⟹   XP_006718803
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381160,971,680 - 61,020,377 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011545360   ⟹   XP_011543662
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381160,971,680 - 61,020,377 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011545362   ⟹   XP_011543664
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381160,971,680 - 61,020,377 (+)NCBI
Sequence:
RefSeq Acc Id: XM_047427874   ⟹   XP_047283830
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381160,971,680 - 61,020,377 (+)NCBI
RefSeq Acc Id: XM_047427875   ⟹   XP_047283831
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381160,971,680 - 61,020,377 (+)NCBI
RefSeq Acc Id: XM_047427876   ⟹   XP_047283832
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381160,971,680 - 61,020,377 (+)NCBI
RefSeq Acc Id: XM_047427877   ⟹   XP_047283833
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381160,971,680 - 61,020,377 (+)NCBI
RefSeq Acc Id: XM_047427878   ⟹   XP_047283834
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381160,971,680 - 61,020,377 (+)NCBI
RefSeq Acc Id: XM_047427879   ⟹   XP_047283835
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381160,971,680 - 61,020,377 (+)NCBI
RefSeq Acc Id: XM_047427880   ⟹   XP_047283836
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381160,971,680 - 61,020,377 (+)NCBI
RefSeq Acc Id: XM_047427881   ⟹   XP_047283837
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381160,971,680 - 61,020,377 (+)NCBI
RefSeq Acc Id: XM_054370518   ⟹   XP_054226493
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01160,922,811 - 60,971,572 (+)NCBI
RefSeq Acc Id: XM_054370519   ⟹   XP_054226494
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01160,922,811 - 60,971,572 (+)NCBI
RefSeq Acc Id: XM_054370520   ⟹   XP_054226495
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01160,922,811 - 60,971,572 (+)NCBI
RefSeq Acc Id: XM_054370521   ⟹   XP_054226496
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01160,922,811 - 60,971,572 (+)NCBI
RefSeq Acc Id: XM_054370522   ⟹   XP_054226497
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01160,922,811 - 60,971,572 (+)NCBI
RefSeq Acc Id: XM_054370523   ⟹   XP_054226498
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01160,922,811 - 60,971,572 (+)NCBI
RefSeq Acc Id: XM_054370524   ⟹   XP_054226499
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01160,922,811 - 60,971,572 (+)NCBI
RefSeq Acc Id: XM_054370525   ⟹   XP_054226500
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01160,922,811 - 60,971,572 (+)NCBI
RefSeq Acc Id: XM_054370526   ⟹   XP_054226501
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01160,922,811 - 60,971,572 (+)NCBI
RefSeq Acc Id: XM_054370527   ⟹   XP_054226502
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01160,922,811 - 60,971,572 (+)NCBI
RefSeq Acc Id: XM_054370528   ⟹   XP_054226503
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01160,922,811 - 60,971,572 (+)NCBI
RefSeq Acc Id: XM_054370529   ⟹   XP_054226504
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01160,922,811 - 60,971,572 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001241679 (Get FASTA)   NCBI Sequence Viewer  
  NP_001241680 (Get FASTA)   NCBI Sequence Viewer  
  NP_006716 (Get FASTA)   NCBI Sequence Viewer  
  XP_006718801 (Get FASTA)   NCBI Sequence Viewer  
  XP_006718802 (Get FASTA)   NCBI Sequence Viewer  
  XP_006718803 (Get FASTA)   NCBI Sequence Viewer  
  XP_011543662 (Get FASTA)   NCBI Sequence Viewer  
  XP_011543664 (Get FASTA)   NCBI Sequence Viewer  
  XP_047283830 (Get FASTA)   NCBI Sequence Viewer  
  XP_047283831 (Get FASTA)   NCBI Sequence Viewer  
  XP_047283832 (Get FASTA)   NCBI Sequence Viewer  
  XP_047283833 (Get FASTA)   NCBI Sequence Viewer  
  XP_047283834 (Get FASTA)   NCBI Sequence Viewer  
  XP_047283835 (Get FASTA)   NCBI Sequence Viewer  
  XP_047283836 (Get FASTA)   NCBI Sequence Viewer  
  XP_047283837 (Get FASTA)   NCBI Sequence Viewer  
  XP_054226493 (Get FASTA)   NCBI Sequence Viewer  
  XP_054226494 (Get FASTA)   NCBI Sequence Viewer  
  XP_054226495 (Get FASTA)   NCBI Sequence Viewer  
  XP_054226496 (Get FASTA)   NCBI Sequence Viewer  
  XP_054226497 (Get FASTA)   NCBI Sequence Viewer  
  XP_054226498 (Get FASTA)   NCBI Sequence Viewer  
  XP_054226499 (Get FASTA)   NCBI Sequence Viewer  
  XP_054226500 (Get FASTA)   NCBI Sequence Viewer  
  XP_054226501 (Get FASTA)   NCBI Sequence Viewer  
  XP_054226502 (Get FASTA)   NCBI Sequence Viewer  
  XP_054226503 (Get FASTA)   NCBI Sequence Viewer  
  XP_054226504 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA86417 (Get FASTA)   NCBI Sequence Viewer  
  AAA86418 (Get FASTA)   NCBI Sequence Viewer  
  AAA86419 (Get FASTA)   NCBI Sequence Viewer  
  AAC51161 (Get FASTA)   NCBI Sequence Viewer  
  AAC51162 (Get FASTA)   NCBI Sequence Viewer  
  AAC51163 (Get FASTA)   NCBI Sequence Viewer  
  AAC51164 (Get FASTA)   NCBI Sequence Viewer  
  AAC51165 (Get FASTA)   NCBI Sequence Viewer  
  AAH33755 (Get FASTA)   NCBI Sequence Viewer  
  AAH78669 (Get FASTA)   NCBI Sequence Viewer  
  AAL40085 (Get FASTA)   NCBI Sequence Viewer  
  AAL40086 (Get FASTA)   NCBI Sequence Viewer  
  AAL40087 (Get FASTA)   NCBI Sequence Viewer  
  AAL40088 (Get FASTA)   NCBI Sequence Viewer  
  AAL40089 (Get FASTA)   NCBI Sequence Viewer  
  ABH04237 (Get FASTA)   NCBI Sequence Viewer  
  ABH04238 (Get FASTA)   NCBI Sequence Viewer  
  BAF85393 (Get FASTA)   NCBI Sequence Viewer  
  CAA43306 (Get FASTA)   NCBI Sequence Viewer  
  EAW73917 (Get FASTA)   NCBI Sequence Viewer  
  EAW73918 (Get FASTA)   NCBI Sequence Viewer  
  EAW73919 (Get FASTA)   NCBI Sequence Viewer  
  EAW73920 (Get FASTA)   NCBI Sequence Viewer  
  EAW73921 (Get FASTA)   NCBI Sequence Viewer  
  EAW73922 (Get FASTA)   NCBI Sequence Viewer  
  EAW73923 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSP00000323280
  ENSP00000323280.7
  ENSP00000340334.5
  ENSP00000340628
  ENSP00000340628.5
  ENSP00000390676
  ENSP00000390676.2
  ENSP00000410638.2
  ENSP00000440055.1
  ENSP00000443747.1
  ENSP00000443748.1
GenBank Protein P30203 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: NP_006716   ⟸   NM_006725
- Peptide Label: isoform 1 precursor
- UniProtKB: Q9Y4K9 (UniProtKB/Swiss-Prot),   Q9Y4K8 (UniProtKB/Swiss-Prot),   Q9Y4K7 (UniProtKB/Swiss-Prot),   Q9UMF2 (UniProtKB/Swiss-Prot),   Q8WWJ7 (UniProtKB/Swiss-Prot),   Q8WWJ6 (UniProtKB/Swiss-Prot),   Q8WWJ5 (UniProtKB/Swiss-Prot),   Q8WWJ4 (UniProtKB/Swiss-Prot),   Q8WWJ3 (UniProtKB/Swiss-Prot),   A4KAD5 (UniProtKB/Swiss-Prot),   A4KAD4 (UniProtKB/Swiss-Prot),   Q9Y4L0 (UniProtKB/Swiss-Prot),   P30203 (UniProtKB/Swiss-Prot),   A8K9I9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001241680   ⟸   NM_001254751
- Peptide Label: isoform 3 precursor
- UniProtKB: Q8N4Q7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001241679   ⟸   NM_001254750
- Peptide Label: isoform 2 precursor
- UniProtKB: Q8N4Q7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006718802   ⟸   XM_006718739
- Peptide Label: isoform X5
- UniProtKB: A8K9I9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006718803   ⟸   XM_006718740
- Peptide Label: isoform X6
- UniProtKB: A8K9I9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006718801   ⟸   XM_006718738
- Peptide Label: isoform X2
- UniProtKB: A8K9I9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011543662   ⟸   XM_011545360
- Peptide Label: isoform X1
- UniProtKB: A8K9I9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011543664   ⟸   XM_011545362
- Peptide Label: isoform X7
- UniProtKB: A8K9I9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSP00000443748   ⟸   ENST00000542254
RefSeq Acc Id: ENSP00000440055   ⟸   ENST00000542157
RefSeq Acc Id: ENSP00000390676   ⟸   ENST00000452451
RefSeq Acc Id: ENSP00000340628   ⟸   ENST00000352009
RefSeq Acc Id: ENSP00000323280   ⟸   ENST00000313421
RefSeq Acc Id: ENSP00000443747   ⟸   ENST00000538611
RefSeq Acc Id: ENSP00000410638   ⟸   ENST00000433107
RefSeq Acc Id: ENSP00000340334   ⟸   ENST00000344931
RefSeq Acc Id: XP_047283837   ⟸   XM_047427881
- Peptide Label: isoform X13
RefSeq Acc Id: XP_047283831   ⟸   XM_047427875
- Peptide Label: isoform X4
RefSeq Acc Id: XP_047283830   ⟸   XM_047427874
- Peptide Label: isoform X3
RefSeq Acc Id: XP_047283832   ⟸   XM_047427876
- Peptide Label: isoform X8
RefSeq Acc Id: XP_047283835   ⟸   XM_047427879
- Peptide Label: isoform X11
RefSeq Acc Id: XP_047283836   ⟸   XM_047427880
- Peptide Label: isoform X12
RefSeq Acc Id: XP_047283833   ⟸   XM_047427877
- Peptide Label: isoform X9
RefSeq Acc Id: XP_047283834   ⟸   XM_047427878
- Peptide Label: isoform X10
RefSeq Acc Id: XP_054226493   ⟸   XM_054370518
- Peptide Label: isoform X1
RefSeq Acc Id: XP_054226496   ⟸   XM_054370521
- Peptide Label: isoform X4
RefSeq Acc Id: XP_054226497   ⟸   XM_054370522
- Peptide Label: isoform X5
RefSeq Acc Id: XP_054226498   ⟸   XM_054370523
- Peptide Label: isoform X6
RefSeq Acc Id: XP_054226494   ⟸   XM_054370519
- Peptide Label: isoform X2
RefSeq Acc Id: XP_054226495   ⟸   XM_054370520
- Peptide Label: isoform X3
RefSeq Acc Id: XP_054226499   ⟸   XM_054370524
- Peptide Label: isoform X7
RefSeq Acc Id: XP_054226500   ⟸   XM_054370525
- Peptide Label: isoform X8
RefSeq Acc Id: XP_054226503   ⟸   XM_054370528
- Peptide Label: isoform X11
RefSeq Acc Id: XP_054226504   ⟸   XM_054370529
- Peptide Label: isoform X12
RefSeq Acc Id: XP_054226501   ⟸   XM_054370526
- Peptide Label: isoform X9
RefSeq Acc Id: XP_054226502   ⟸   XM_054370527
- Peptide Label: isoform X10
Protein Domains
SRCR

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P30203-F1-model_v2 AlphaFold P30203 1-668 view protein structure

Promoters
RGD ID:6788605
Promoter ID:HG_KWN:13037
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   Lymphoblastoid
Transcripts:ENST00000344028,   ENST00000346437,   NM_006725,   UC001NQP.1,   UC001NQR.1,   UC001NQS.1,   UC001NQT.1,   UC009YNI.1,   UC009YNJ.1
Position:
Human AssemblyChrPosition (strand)Source
Build 361160,495,546 - 60,496,046 (+)MPROMDB
RGD ID:6809960
Promoter ID:HG_ACW:12310
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell
Transcripts:CD6.GAPR07,   CD6.JAPR07
Position:
Human AssemblyChrPosition (strand)Source
Build 361160,531,431 - 60,531,931 (+)MPROMDB
RGD ID:7220509
Promoter ID:EPDNEW_H16000
Type:initiation region
Name:CD6_1
Description:CD6 molecule
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381160,971,736 - 60,971,796EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:1691 AgrOrtholog
COSMIC CD6 COSMIC
Ensembl Genes ENSG00000013725 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000313421 ENTREZGENE
  ENST00000313421.11 UniProtKB/Swiss-Prot
  ENST00000344931 ENTREZGENE
  ENST00000344931.9 UniProtKB/TrEMBL
  ENST00000352009 ENTREZGENE
  ENST00000352009.9 UniProtKB/Swiss-Prot
  ENST00000433107.6 UniProtKB/TrEMBL
  ENST00000452451 ENTREZGENE
  ENST00000452451.6 UniProtKB/Swiss-Prot
  ENST00000538611.1 UniProtKB/TrEMBL
  ENST00000542157.5 UniProtKB/TrEMBL
  ENST00000542254.5 UniProtKB/TrEMBL
Gene3D-CATH 3.10.250.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000013725 GTEx
HGNC ID HGNC:1691 ENTREZGENE
Human Proteome Map CD6 Human Proteome Map
InterPro SRCR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SRCR-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SRCR-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:923 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 923 ENTREZGENE
OMIM 186720 OMIM
PANTHER DELETED IN MALIGNANT BRAIN TUMORS 1 PROTEIN UniProtKB/TrEMBL
  SRCR DOMAIN-CONTAINING PROTEIN UniProtKB/Swiss-Prot
  SRCR DOMAIN-CONTAINING PROTEIN UniProtKB/Swiss-Prot
  SRCR DOMAIN-CONTAINING PROTEIN UniProtKB/TrEMBL
  SRCR DOMAIN-CONTAINING PROTEIN UniProtKB/TrEMBL
Pfam SRCR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA26230 PharmGKB
PRINTS SPERACTRCPTR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE SRCR_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SRCR_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART SM00202 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF56487 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A4KAD4 ENTREZGENE
  A4KAD5 ENTREZGENE
  A8K9I9 ENTREZGENE, UniProtKB/TrEMBL
  CD6_HUMAN UniProtKB/Swiss-Prot
  E7ER04_HUMAN UniProtKB/TrEMBL
  F5H835_HUMAN UniProtKB/TrEMBL
  F6UFK6_HUMAN UniProtKB/TrEMBL
  G5E973_HUMAN UniProtKB/TrEMBL
  H0YGL3_HUMAN UniProtKB/TrEMBL
  L8E9F6_HUMAN UniProtKB/TrEMBL
  P30203 ENTREZGENE
  Q6AZ88_HUMAN UniProtKB/TrEMBL
  Q8N4Q7 ENTREZGENE, UniProtKB/TrEMBL
  Q8WWJ3 ENTREZGENE
  Q8WWJ4 ENTREZGENE
  Q8WWJ5 ENTREZGENE
  Q8WWJ6 ENTREZGENE
  Q8WWJ7 ENTREZGENE
  Q9UMF2 ENTREZGENE
  Q9Y4K7 ENTREZGENE
  Q9Y4K8 ENTREZGENE
  Q9Y4K9 ENTREZGENE
  Q9Y4L0 ENTREZGENE
UniProt Secondary A4KAD4 UniProtKB/Swiss-Prot
  A4KAD5 UniProtKB/Swiss-Prot
  Q8WWJ3 UniProtKB/Swiss-Prot
  Q8WWJ4 UniProtKB/Swiss-Prot
  Q8WWJ5 UniProtKB/Swiss-Prot
  Q8WWJ6 UniProtKB/Swiss-Prot
  Q8WWJ7 UniProtKB/Swiss-Prot
  Q9UMF2 UniProtKB/Swiss-Prot
  Q9Y4K7 UniProtKB/Swiss-Prot
  Q9Y4K8 UniProtKB/Swiss-Prot
  Q9Y4K9 UniProtKB/Swiss-Prot
  Q9Y4L0 UniProtKB/Swiss-Prot