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Gene: TEAD1 (TEA domain transcription factor 1) Homo sapiens
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Symbol: TEAD1
Name: TEA domain transcription factor 1
Description: Exhibits DNA-binding transcription factor activity, RNA polymerase II-specific and cis-regulatory region sequence-specific DNA binding activity. Involved in hippo signaling; positive regulation of pri-miRNA transcription by RNA polymerase II; and protein-containing complex assembly. Localizes to TEAD-1-YAP complex and nucleoplasm. Implicated in Sveinsson chorioretinal atrophy.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AA; atrophia areata, peripapillary chorioretinal degeneration; FLJ17970; NTEF-1; protein GT-IIC; REF1; TCF-13; TCF13; TEA domain family member 1 (SV40 transcriptional enhancer factor); TEAD-1; TEF-1; transcription factor 13; transcriptional enhancer factor 1; transcriptional enhancer factor TEF-1
Orthologs:
Mus musculus (house mouse) : Tead1 (TEA domain family member 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Tead1 (TEA domain transcription factor 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tead1 (TEA domain transcription factor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : TEAD1 (TEA domain transcription factor 1)
Canis lupus familiaris (dog) : TEAD1 (TEA domain transcription factor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tead1 (TEA domain transcription factor 1)
Sus scrofa (pig) : TEAD1 (TEA domain transcription factor 1)
Chlorocebus sabaeus (African green monkey) : TEAD1 (TEA domain transcription factor 1)
Heterocephalus glaber (naked mole-rat) : Tead1 (TEA domain transcription factor 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1112,674,421 - 12,944,737 (+)EnsemblGRCh38hg38GRCh38
GRCh381112,674,421 - 12,944,737 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371112,695,969 - 12,966,284 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361112,652,545 - 12,922,875 (+)NCBINCBI36hg18NCBI36
Build 341112,742,300 - 12,922,859NCBI
Celera1112,823,287 - 13,092,362 (+)NCBI
Cytogenetic Map11p15.3NCBI
HuRef1112,376,359 - 12,646,393 (+)NCBIHuRef
CHM1_11112,694,856 - 12,965,213 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on TEAD1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1351522
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-07-28
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.