Gene: CSTF2 (cleavage stimulation factor subunit 2) Homo sapiens
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Symbol: CSTF2
Name: cleavage stimulation factor subunit 2
Description: This gene encodes a nuclear protein with an RRM (RNA recognition motif) domain. The protein is a member of the cleavage stimulation factor (CSTF) complex that is involved in the 3' end cleavage and polyadenylation of pre-mRNAs. Specifically, this protein binds GU-rich elements within the 3'-untranslated region of mRNAs. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: betaCstF-64 variant 2; CF-1 64 kDa subunit; cleavage stimulation factor 64 kDa subunit; cleavage stimulation factor, 3' pre-RNA, subunit 2; cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kD; cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa; CSTF 64 kDa subunit; CstF-64
Orthologs:
Mus musculus (house mouse) : Cstf2 (cleavage stimulation factor, 3' pre-RNA subunit 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Cstf2 (cleavage stimulation factor subunit 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cstf2 (cleavage stimulation factor subunit 2)
Pan paniscus (bonobo/pygmy chimpanzee) : CSTF2 (cleavage stimulation factor subunit 2)
Canis lupus familiaris (dog) : CSTF2 (cleavage stimulation factor subunit 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cstf2 (cleavage stimulation factor subunit 2)
Sus scrofa (pig) : CSTF2 (cleavage stimulation factor subunit 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X100,820,359 - 100,843,534 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X100,075,348 - 100,095,924 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X99,962,004 - 99,982,580 (+)NCBINCBI36hg18NCBI36
Build 34X99,881,528 - 99,902,066NCBI
CeleraX100,594,139 - 100,614,716 (+)NCBI
Cytogenetic MapXq22.1NCBI
HuRefX89,874,108 - 89,894,686 (+)NCBIHuRef
CHM1_1X99,968,275 - 99,989,439 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on CSTF2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1351144
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-05-14
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.