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Gene: XAGE2 (X antigen family member 2) Homo sapiens
Symbol: XAGE2
Name: X antigen family member 2
Description: This gene is a member of the XAGE subfamily, which belongs to the GAGE family. The GAGE genes are expressed in a variety of tumors and in some fetal and reproductive tissues. This gene is strongly expressed in normal testis, and in Ewing's sarcoma, rhabdomyosarcoma, a breast cancer and a germ cell tumor. The protein encoded by this gene shares a sequence similarity with other GAGE/PAGE proteins. Because of the expression pattern and the sequence similarity, this protein also belongs to a family of CT (cancer-testis) antigens. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: cancer/testis antigen 12.2; cancer/testis antigen family 12, member 2; CT12.2; G antigen family D member 3; G antigen, family D, 3; GAGED3; X antigen family, member 2; X antigen family, member 2-like; X antigen family, member 2B; XAGE-2; XAGE2B
Pan paniscus (bonobo/pygmy chimpanzee) : XAGE2 (X antigen family member 2)
Canis lupus familiaris (dog) : LOC100688778 (putative G antigen family E member 3)
Chlorocebus sabaeus (green monkey) : XAGE2 (X antigen family member 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 EnsemblX52,369,021 - 52,375,680 (+)Ensembl
GRCh38X52,368,996 - 52,375,683 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X52,111,931 - 52,118,826 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X52,397,076 - 52,403,821 (-)NCBINCBI36hg18NCBI36
Build 34X52,213,374 - 52,220,117NCBI
CeleraX55,607,877 - 55,614,622 (-)NCBI
Cytogenetic MapXp11.22NCBI
HuRefX49,516,495 - 49,523,197 (+)NCBIHuRef
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on XAGE2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1350959
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.