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Gene: MIR129-1 (microRNA 129-1) Homo sapiens
Symbol: MIR129-1
Name: microRNA 129-1
Description: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
Type: ncrna
Also known as: mir-129-1; MIR-129b; MIRN129-1
Mus musculus (house mouse) : Mir129-1 (microRNA 129-1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Mir129-1 (microRNA 129-1)  Alliance
Canis lupus familiaris (dog) : MIR129-1 (microRNA mir-129-1)
Sus scrofa (pig) : MIR129B (microRNA mir-129b)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl7128,207,872 - 128,207,943 (+)EnsemblGRCh38hg38GRCh38
GRCh387128,207,872 - 128,207,943 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh377127,847,925 - 127,847,996 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 367127,635,160 - 127,635,231 (+)NCBINCBI36hg18NCBI36
Celera7122,651,214 - 122,651,285 (+)NCBI
Cytogenetic Map7q32.1NCBI
HuRef7122,208,895 - 122,208,966 (+)NCBIHuRef
CHM1_17127,781,240 - 127,781,311 (+)NCBICHM1_1
CRA_TCAGchr7v27127,231,050 - 127,231,121 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Clinical Variants

Additional Information

External Database Links
More on MIR129-1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1350855
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-06-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.