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Gene: SCIN (scinderin) Homo sapiens
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Symbol: SCIN
Name: scinderin
Description: Predicted to have actin filament binding activity; calcium ion binding activity; and phospholipid binding activity. Involved in several processes, including actin filament severing; positive regulation of megakaryocyte differentiation; and regulation of actin filament polymerization. Localizes to the plasma membrane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: adseverin; KIAA1905
Orthologs:
Mus musculus (house mouse) : Scin (scinderin)  MGI  Alliance
Rattus norvegicus (Norway rat) : Scin (scinderin)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Scin (scinderin)
Pan paniscus (bonobo/pygmy chimpanzee) : SCIN (scinderin)
Canis lupus familiaris (dog) : SCIN (scinderin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Scin (scinderin)
Sus scrofa (pig) : SCIN (scinderin)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl712,570,577 - 12,660,182 (+)Ensembl
GRCh38712,570,720 - 12,660,182 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37712,609,989 - 12,693,228 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36712,595,673 - 12,659,752 (+)NCBINCBI36hg18NCBI36
Build 34712,402,387 - 12,466,467NCBI
Celera712,587,891 - 12,670,905 (+)NCBI
Cytogenetic Map7p21.3NCBI
HuRef712,488,818 - 12,571,812 (+)NCBIHuRef
CHM1_1712,610,380 - 12,693,312 (+)NCBICHM1_1
CRA_TCAGchr7v2712,661,354 - 12,744,363 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on SCIN
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1350815
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.