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Gene: NECTIN1 (nectin cell adhesion molecule 1) Homo sapiens
Symbol: NECTIN1
Name: nectin cell adhesion molecule 1
Description: Exhibits cell adhesion molecule binding activity and identical protein binding activity. Predicted to be involved in heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules and homophilic cell adhesion via plasma membrane adhesion molecules. Localizes to adherens junction. Implicated in cleft lip; cleft lip-palate-ectodermal dysplasia syndrome; cleft palate; and ectodermal dysplasia.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CD111; CLPED1; ectodermal dysplasia 4 (Margarita Island type); ED4; herpes simplex virus type 1 sensitivity; herpes virus entry mediator C; herpesvirus Ig-like receptor; HIgR; HV1S; HVEC; MGC142031; MGC16207; nectin 1; nectin-1; OFC7; poliovirus receptor-like 1; poliovirus receptor-related 1 (herpesvirus entry mediator C); poliovirus receptor-related protein 1; PRR; PRR1; PVRL1; PVRR; PVRR1; SK-12
Mus musculus (house mouse) : Nectin1 (nectin cell adhesion molecule 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Nectin1 (nectin cell adhesion molecule 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nectin1 (nectin cell adhesion molecule 1)
Pan paniscus (bonobo/pygmy chimpanzee) : NECTIN1 (nectin cell adhesion molecule 1)
Canis lupus familiaris (dog) : NECTIN1 (nectin cell adhesion molecule 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nectin1 (nectin cell adhesion molecule 1)
Sus scrofa (pig) : NECTIN1 (nectin cell adhesion molecule 1)
Chlorocebus sabaeus (African green monkey) : NECTIN1 (nectin cell adhesion molecule 1)
Heterocephalus glaber (naked mole-rat) : Nectin1 (nectin cell adhesion molecule 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl11119,623,408 - 119,729,200 (-)EnsemblGRCh38hg38GRCh38
GRCh3811119,638,098 - 119,729,200 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3711119,508,808 - 119,599,435 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3611119,014,018 - 119,104,645 (-)NCBINCBI36hg18NCBI36
Build 3411119,050,309 - 119,104,645NCBI
Celera11116,669,897 - 116,760,980 (-)NCBI
Cytogenetic Map11q23.3NCBI
HuRef11115,451,054 - 115,541,412 (-)NCBIHuRef
CHM1_111119,396,685 - 119,487,290 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on NECTIN1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1350722
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.