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Gene: MAGEB2 (MAGE family member B2) Homo sapiens
Symbol: MAGEB2
Name: MAGE family member B2
Description: This gene is a member of the MAGEB gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 68% sequence identity to each other. The promoters and first exons of the MAGEB genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. This gene is localized in the DSS (dosage-sensitive sex reversal) critical region. It is expressed in testis and placenta, and in a significant fraction of tumors of various histological types. The MAGEB genes are clustered on chromosome Xp22-p21. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: cancer/testis antigen 3.2; cancer/testis antigen family 3, member 2; CT3.2; DAM6; DSS-AHC critical interval MAGE superfamily 6; DSS/AHC critical interval MAGE superfamily 6; MAGE XP-2 antigen; MAGE-B2 antigen; MAGE-XP-2; melanoma antigen family B, 2; melanoma antigen family B2; melanoma-associated antigen B2; MGC26438
Rattus norvegicus (Norway rat) : Mageb2 (MAGE family member B2)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : MAGEB2 (MAGE family member B2)
Canis lupus familiaris (dog) : LOC491803 (melanoma-associated antigen B1)
Sus scrofa (pig) : LOC102159844 (melanoma-associated antigen B4-like)
Chlorocebus sabaeus (African green monkey) : MAGEB2 (MAGE family member B2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 EnsemblX30,215,563 - 30,220,089 (+)Ensembl
GRCh38X30,215,563 - 30,220,089 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X30,233,675 - 30,238,206 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X30,143,601 - 30,148,127 (+)NCBINCBI36hg18NCBI36
Build 34X29,993,336 - 29,997,861NCBI
CeleraX34,355,297 - 34,359,830 (+)NCBI
Cytogenetic MapXp21.2NCBI
HuRefX27,970,706 - 27,975,164 (+)NCBIHuRef
CHM1_1X30,264,618 - 30,269,149 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on MAGEB2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1350701
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.