TTTY4B (testis expressed transcript, Y-linked 4B) - Rat Genome Database

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Gene: TTTY4B (testis expressed transcript, Y-linked 4B) Homo sapiens
Analyze
Symbol: TTTY4B
Name: testis expressed transcript, Y-linked 4B (Ensembl:testis-specific transcript, Y-linked 4B)
RGD ID: 1350699
HGNC Page HGNC:31891
Description: There are three copies of this gene on chromosome Y. This record represents the middle copy, which is within the P1 palindrome. [provided by RefSeq, Jul 2008]
Type: ncrna (Ensembl: lncRNA)
RefSeq Status: VALIDATED
Previously known as: LINC00124; NCRNA00124; testis-specific transcript, Y-linked 4B; testis-specific transcript, Y-linked 4B (non-protein coding)
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38Y24,570,202 - 24,607,025 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblY24,570,202 - 24,607,025 (+)EnsemblGRCh38hg38GRCh38
GRCh37Y26,716,349 - 26,753,172 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36Y25,125,737 - 25,162,560 (+)NCBINCBI36Build 36hg18NCBI36
CeleraY10,888,193 - 10,924,998 (+)NCBICelera
Cytogenetic MapYq11.23NCBI
HuRefY17,892,011 - 17,901,668 (+)NCBIHuRef
T2T-CHM13v2.0Y24,255,525 - 24,292,324 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
Autism  (IAGP)
References
Additional References at PubMed
PMID:12815422  


Genomics


Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 Yp11.2-q12(chrY:2786811-56885333)x2 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000050325]|Global developmental delay [RCV000050326]|Abnormality of the heart [RCV000050327]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000050325]|See cases [RCV000050325] ChrY:2786811..56885333 [GRCh38]
ChrY:2654852..59031480 [GRCh37]
ChrY:Yp11.2-q12		 pathogenic
GRCh37/hg19 Yq11.21-12(chrY:14698756-59031480)x0 copy number loss See cases [RCV000050825] ChrY:14698756..59031480 [GRCh37]
ChrY:13208776..57440868 [NCBI36]
ChrY:Yq11.21-12		 pathogenic
GRCh38/hg38 Yq11.222-12(chrY:18891467-57208726)x0 copy number loss See cases [RCV000050370] ChrY:18891467..57208726 [GRCh38]
ChrY:21053353..59354877 [GRCh37]
ChrY:19512741..57764265 [NCBI36]
ChrY:Yq11.222-12		 pathogenic
GRCh38/hg38 Yq11.221-12(chrY:13404515-57208726)x0 copy number loss Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051778]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051778]|See cases [RCV000051778] ChrY:13404515..57208726 [GRCh38]
ChrY:15516395..59354877 [GRCh37]
ChrY:Yq11.221-12		 pathogenic
GRCh38/hg38 Yp11.2-q11.23(chrY:2786811-26389995)x0 copy number loss Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051767]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051767]|See cases [RCV000051767] ChrY:2786811..26389995 [GRCh38]
ChrY:2654852..28536142 [GRCh37]
ChrY:2714852..26945530 [NCBI36]
ChrY:Yp11.2-q11.23		 pathogenic
GRCh38/hg38 Yq11.221-12(chrY:12586822-57208726)x0 copy number loss Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051768]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051768]|See cases [RCV000051768] ChrY:12586822..57208726 [GRCh38]
ChrY:14698756..59354877 [GRCh37]
ChrY:13208776..57764265 [NCBI36]
ChrY:Yq11.221-12		 pathogenic
GRCh37/hg19 Yp11.3-q12(chrY:2651665-59031480)x2 copy number gain See cases [RCV000052585] ChrY:2651665..59031480 [GRCh37]
ChrY:2711665..57440868 [NCBI36]
ChrY:Yp11.3-q12		 pathogenic
GRCh38/hg38 Yp11.2-q11.23(chrY:2786611-26409996)x2 copy number gain See cases [RCV000052586] ChrY:2786611..26409996 [GRCh38]
ChrY:2654652..28556143 [GRCh37]
ChrY:2714652..26965531 [NCBI36]
ChrY:Yp11.2-q11.23		 pathogenic
GRCh38/hg38 Yp11.2-q11.23(chrY:2786811-26463830)x2 copy number gain See cases [RCV000052587] ChrY:2786811..26463830 [GRCh38]
ChrY:2654852..28609977 [GRCh37]
ChrY:2714852..27019365 [NCBI36]
ChrY:Yp11.2-q11.23		 pathogenic
GRCh38/hg38 Yp11.2-q11.23(chrY:2786811-26483746)x2 copy number gain See cases [RCV000052588] ChrY:2786811..26483746 [GRCh38]
ChrY:2654852..28629893 [GRCh37]
ChrY:2714852..27039281 [NCBI36]
ChrY:Yp11.2-q11.23		 pathogenic
GRCh38/hg38 Yp11.2-q12(chrY:2783624-26637948)x2 copy number gain See cases [RCV000052551] ChrY:2783624..26637948 [GRCh38]
ChrY:2651665..28784095 [GRCh37]
ChrY:2711665..27193483 [NCBI36]
ChrY:Yp11.2-q12		 pathogenic
GRCh38/hg38 Yp11.2-q11.23(chrY:6478684-26574618)x2 copy number gain See cases [RCV000054344] ChrY:6478684..26574618 [GRCh38]
ChrY:6346725..28720765 [GRCh37]
ChrY:6406725..27130153 [NCBI36]
ChrY:Yp11.2-q11.23		 pathogenic
GRCh38/hg38 Yq11.221-12(chrY:14076802-57165209)x0 copy number loss See cases [RCV000133870] ChrY:14076802..57165209 [GRCh38]
ChrY:16188682..59311360 [GRCh37]
ChrY:14698076..57720748 [NCBI36]
ChrY:Yq11.221-12		 pathogenic
GRCh38/hg38 Yq11.221-12(chrY:13404515-57208726)x0 copy number loss See cases [RCV000051778] ChrY:13404515..57208726 [GRCh38]
ChrY:15516395..59354877 [GRCh37]
ChrY:14025789..57764265 [NCBI36]
ChrY:Yq11.221-12		 pathogenic
GRCh37/hg19 Yp11.31-q12(chrY:2654852-59031480)x0 copy number loss See cases [RCV000133673] ChrY:2654852..59031480 [GRCh37]
ChrY:2714852..57440868 [NCBI36]
ChrY:Yp11.31-q12		 pathogenic
GRCh37/hg19 Yp11.31-q12(chrY:2654852-59031480)x3 copy number gain See cases [RCV000133672] ChrY:2654852..59031480 [GRCh37]
ChrY:2714852..57440868 [NCBI36]
ChrY:Yp11.31-q12		 pathogenic
GRCh38/hg38 Yq11.221-12(chrY:12965721-57212647)x0 copy number loss See cases [RCV000135325] ChrY:12965721..57212647 [GRCh38]
ChrY:15077631..59358798 [GRCh37]
ChrY:13587025..57768186 [NCBI36]
ChrY:Yq11.221-12		 pathogenic
GRCh38/hg38 Yq11.223-11.23(chrY:21927773-26133012)x3 copy number gain See cases [RCV000135297] ChrY:21927773..26133012 [GRCh38]
ChrY:24073920..28279159 [GRCh37]
ChrY:Yq11.223-11.23		 benign
GRCh38/hg38 Yq11.223-11.23(chrY:21927773-26133012)x0 copy number loss See cases [RCV000135298] ChrY:21927773..26133012 [GRCh38]
ChrY:24073920..28279159 [GRCh37]
ChrY:22483308..26688547 [NCBI36]
ChrY:Yq11.223-11.23		 pathogenic
GRCh38/hg38 Yp11.2-q11.23(chrY:6270281-26463761)x0 copy number loss See cases [RCV000134844] ChrY:6270281..26463761 [GRCh38]
ChrY:6138322..28609908 [GRCh37]
ChrY:6198322..27019296 [NCBI36]
ChrY:Yp11.2-q11.23		 pathogenic
GRCh37/hg19 Yq11.221-12(chrY:16183453-59011762)x2 copy number gain See cases [RCV000135766] ChrY:16183453..59011762 [GRCh37]
ChrY:14692847..57421150 [NCBI36]
ChrY:Yq11.221-12		 pathogenic
GRCh38/hg38 Yq11.222-12(chrY:18664321-26637948)x2 copy number gain See cases [RCV000135767] ChrY:18664321..26637948 [GRCh38]
ChrY:20826207..28784095 [GRCh37]
ChrY:19285595..27193483 [NCBI36]
ChrY:Yq11.222-12		 pathogenic
GRCh38/hg38 Yp11.32-q12(chrY:10701-57189762) copy number loss See cases [RCV000135689] ChrY:10701..57189762 [GRCh38]
ChrY:10701..59335913 [GRCh37]
ChrY:701..57745301 [NCBI36]
ChrY:Yp11.32-q12		 pathogenic
GRCh38/hg38 Yp11.32-q12(chrY:10701-57189762)x0 copy number loss See cases [RCV000135690] ChrY:10701..57189762 [GRCh38]
ChrY:10701..59335913 [GRCh37]
ChrY:701..57745301 [NCBI36]
ChrY:Yp11.32-q12		 pathogenic
GRCh38/hg38 Yq11.221-12(chrY:13948013-57208726)x0 copy number loss See cases [RCV000135529] ChrY:13948013..57208726 [GRCh38]
ChrY:16059893..59354877 [GRCh37]
ChrY:14569287..57764265 [NCBI36]
ChrY:Yq11.221-12		 pathogenic
GRCh38/hg38 Yp11.2-q11.23(chrY:2786596-26575961)x0 copy number loss See cases [RCV000136110] ChrY:2786596..26575961 [GRCh38]
ChrY:2654637..28722108 [GRCh37]
ChrY:2714637..27131496 [NCBI36]
ChrY:Yp11.2-q11.23		 pathogenic
GRCh38/hg38 Yq11.221-12(chrY:15631816-57211010)x0 copy number loss See cases [RCV000135882] ChrY:15631816..57211010 [GRCh38]
ChrY:17743696..59357161 [GRCh37]
ChrY:16253090..57766549 [NCBI36]
ChrY:Yq11.221-12		 pathogenic
GRCh38/hg38 Yq11.222-12(chrY:18545732-57189762)x0 copy number loss See cases [RCV000137556] ChrY:18545732..57189762 [GRCh38]
ChrY:20707618..59335913 [GRCh37]
ChrY:19167006..57745301 [NCBI36]
ChrY:Yq11.222-12		 pathogenic
GRCh38/hg38 Yq11.221-12(chrY:14062885-57189762)x0 copy number loss See cases [RCV000138875] ChrY:14062885..57189762 [GRCh38]
ChrY:16174765..59335913 [GRCh37]
ChrY:14684159..57745301 [NCBI36]
ChrY:Yq11.221-12		 pathogenic
GRCh38/hg38 Yq11.223-11.23(chrY:22727003-25749348)x0 copy number loss See cases [RCV000138341] ChrY:22727003..25749348 [GRCh38]
ChrY:24873150..27895495 [GRCh37]
ChrY:23282538..26304883 [NCBI36]
ChrY:Yq11.223-11.23		 pathogenic
GRCh37/hg19 Yp11.31-q12(chrY:2650559-59032389)x2 copy number gain See cases [RCV000138422] ChrY:2650559..59032389 [GRCh37]
ChrY:2710559..57441777 [NCBI36]
ChrY:Yp11.31-q12		 pathogenic
GRCh38/hg38 Yp11.2-q12(chrY:2133003-56884424)x0 copy number loss See cases [RCV000139324] ChrY:2133003..56884424 [GRCh38]
ChrY:1167123..59030571 [GRCh37]
ChrY:1137123..57439959 [NCBI36]
ChrY:Yp11.2-q12		 pathogenic
GRCh38/hg38 Yq11.221-12(chrY:16311571-57190586)x0 copy number loss See cases [RCV000139941] ChrY:16311571..57190586 [GRCh38]
ChrY:18423451..59336737 [GRCh37]
ChrY:16932845..57746125 [NCBI36]
ChrY:Yq11.221-12		 pathogenic
GRCh38/hg38 Yp11.31-q12(chrY:378139-57181562)x1 copy number loss See cases [RCV000141411] ChrY:378139..57181562 [GRCh38]
ChrY:288874..59327713 [GRCh37]
ChrY:258874..57737101 [NCBI36]
ChrY:Yp11.31-q12		 pathogenic
GRCh38/hg38 Yq11.21-12(chrY:10624004-57190586)x0 copy number loss See cases [RCV000141809] ChrY:10624004..57190586 [GRCh38]
ChrY:13134518..59336737 [GRCh37]
ChrY:11244518..57746125 [NCBI36]
ChrY:Yq11.21-12		 pathogenic
GRCh38/hg38 Yq11.223-11.23(chrY:23127736-24882383)x0 copy number loss See cases [RCV000141479] ChrY:23127736..24882383 [GRCh38]
ChrY:25273883..27028530 [GRCh37]
ChrY:23683271..25437918 [NCBI36]
ChrY:Yq11.223-11.23		 benign
GRCh38/hg38 Yq11.223-11.23(chrY:23132736-24882383)x0 copy number loss See cases [RCV000141500] ChrY:23132736..24882383 [GRCh38]
ChrY:25278883..27028530 [GRCh37]
ChrY:23688271..25437918 [NCBI36]
ChrY:Yq11.223-11.23		 benign
GRCh38/hg38 Yq11.223-11.23(chrY:23127722-24882383)x0 copy number loss See cases [RCV000141537] ChrY:23127722..24882383 [GRCh38]
ChrY:25273869..27028530 [GRCh37]
ChrY:23683257..25437918 [NCBI36]
ChrY:Yq11.223-11.23		 likely benign
GRCh38/hg38 Yq11.221-12(chrY:12702930-26653790)x1 copy number gain See cases [RCV000142197] ChrY:12702930..26653790 [GRCh38]
ChrY:14814859..28799937 [GRCh37]
ChrY:13324253..27209325 [NCBI36]
ChrY:Yq11.221-12		 pathogenic
GRCh38/hg38 Yq11.221-12(chrY:12881571-26653790)x1 copy number gain See cases [RCV000142059] ChrY:12881571..26653790 [GRCh38]
ChrY:14993486..28799937 [GRCh37]
ChrY:13502880..27209325 [NCBI36]
ChrY:Yq11.221-12		 likely benign
GRCh38/hg38 Yq11.21-12(chrY:11680193-26653790)x4 copy number gain See cases [RCV000143421] ChrY:11680193..26653790 [GRCh38]
ChrY:13800899..28799937 [GRCh37]
ChrY:12310899..27209325 [NCBI36]
ChrY:Yq11.21-12		 likely pathogenic
GRCh38/hg38 Yq11.222-12(chrY:18891467-57208726)x0 copy number loss See cases [RCV000148059] ChrY:18891467..57208726 [GRCh38]
ChrY:21053353..59354877 [GRCh37]
ChrY:19512741..57764265 [NCBI36]
ChrY:Yq11.222-12		 pathogenic
GRCh37/hg19 Yp11.31-q12(chrY:2654852-59031480)x2 copy number gain See cases [RCV000148271] ChrY:2654852..59031480 [GRCh37]
ChrY:2714852..57440868 [NCBI36]
ChrY:Yp11.31-q12		 pathogenic
GRCh37/hg19 Yp11.32-q12(chrY:20297-59358845)x2 copy number gain See cases [RCV000240246] ChrY:20297..59358845 [GRCh37]
ChrY:Yp11.32-q12		 pathogenic
GRCh37/hg19 Yp11.32-q12(chrY:10701-59349277)x1 copy number loss See cases [RCV000240213] ChrY:10701..59349277 [GRCh37]
ChrY:Yp11.32-q12		 pathogenic
GRCh37/hg19 Yp11.32-q12(chrY:21267-59349649)x2 copy number gain See cases [RCV000239787] ChrY:21267..59349649 [GRCh37]
ChrY:Yp11.32-q12		 pathogenic
GRCh37/hg19 Yp11.32-q12(chrY:100002-59353228)x2 copy number gain See cases [RCV000239812] ChrY:100002..59353228 [GRCh37]
ChrY:Yp11.32-q12		 pathogenic
GRCh37/hg19 Yp11.32-q12(chrY:21267-59337042)x2 copy number gain See cases [RCV000239958] ChrY:21267..59337042 [GRCh37]
ChrY:Yp11.32-q12		 pathogenic
GRCh37/hg19 Yq11.221-12(chrY:16188682-59349649)x0 copy number loss See cases [RCV000240102] ChrY:16188682..59349649 [GRCh37]
ChrY:Yq11.221-12		 pathogenic
GRCh37/hg19 Yp11.32-q12(chrY:126426-59349649)x2 copy number gain See cases [RCV000240301] ChrY:126426..59349649 [GRCh37]
ChrY:Yp11.32-q12		 pathogenic
GRCh37/hg19 Yp11.32-q12(chrY:126426-59353228)x2 copy number gain See cases [RCV000240305] ChrY:126426..59353228 [GRCh37]
ChrY:Yp11.32-q12		 pathogenic
GRCh37/hg19 Yq11.221-12(chrY:15415024-59349591)x0 copy number loss See cases [RCV000446382] ChrY:15415024..59349591 [GRCh37]
ChrY:Yq11.221-12		 pathogenic
GRCh37/hg19 Yq11.223-12(chrY:24108372-59358798)x0 copy number loss See cases [RCV000447015] ChrY:24108372..59358798 [GRCh37]
ChrY:Yq11.223-12		 pathogenic
GRCh37/hg19 Yq11.222-12(chrY:20805226-59336998)x0 copy number loss See cases [RCV000447602] ChrY:20805226..59336998 [GRCh37]
ChrY:Yq11.222-12		 pathogenic
GRCh37/hg19 Yp11.32-q12(chrY:20297-59356174) copy number loss See cases [RCV000448395] ChrY:20297..59356174 [GRCh37]
ChrY:Yp11.32-q12		 pathogenic
GRCh37/hg19 Yq11.222-11.23(chrY:20359545-27839018)x2 copy number gain See cases [RCV000448226] ChrY:20359545..27839018 [GRCh37]
ChrY:Yq11.222-11.23		 likely benign
GRCh37/hg19 Yq11.223-12(chrY:24073794-59336737)x0 copy number loss See cases [RCV000512099] ChrY:24073794..59336737 [GRCh37]
ChrY:Yq11.223-12		 pathogenic
GRCh37/hg19 Yq11.223-12(chrY:26137299-59336737)x0 copy number loss See cases [RCV000512115] ChrY:26137299..59336737 [GRCh37]
ChrY:Yq11.223-12		 likely pathogenic
GRCh37/hg19 Yp11.32-q12(chrY:1684070-36905226)x3 copy number gain See cases [RCV000510438] ChrY:1684070..36905226 [GRCh37]
ChrY:Yp11.32-q12		 uncertain significance
GRCh37/hg19 Yq11.21-12(chrY:13871147-59336737)x0 copy number loss See cases [RCV000510252] ChrY:13871147..59336737 [GRCh37]
ChrY:Yq11.21-12		 pathogenic
GRCh37/hg19 Yq11.223-11.23(chrY:25849444-27811878)x0 copy number loss See cases [RCV000510651] ChrY:25849444..27811878 [GRCh37]
ChrY:Yq11.223-11.23		 uncertain significance
GRCh37/hg19 Yp11.31-q11.23(chrY:2650141-28799937)x2 copy number gain See cases [RCV000510700] ChrY:2650141..28799937 [GRCh37]
ChrY:Yp11.31-q11.23		 uncertain significance
GRCh37/hg19 Yp11.31-q11.23(chrY:2650141-28799937)x0 copy number loss See cases [RCV000511418] ChrY:2650141..28799937 [GRCh37]
ChrY:Yp11.31-q11.23		 pathogenic
GRCh37/hg19 Yp11.32-q11.23(chrY:168546-28451874)x1 copy number loss See cases [RCV000511281] ChrY:168546..28451874 [GRCh37]
ChrY:Yp11.32-q11.23		 pathogenic
GRCh37/hg19 Yq11.23(chrY:26241299-27699077)x0 copy number loss See cases [RCV000512320] ChrY:26241299..27699077 [GRCh37]
ChrY:Yq11.23		 uncertain significance
GRCh37/hg19 Yq11.23(chrY:26241299-27723547)x0 copy number loss not provided [RCV000684429] ChrY:26241299..27723547 [GRCh37]
ChrY:Yq11.23		 uncertain significance
GRCh37/hg19 Yq11.223-11.23(chrY:24740855-28321739)x0 copy number loss not provided [RCV000684435] ChrY:24740855..28321739 [GRCh37]
ChrY:Yq11.223-11.23		 pathogenic
GRCh37/hg19 Yq11.223-11.23(chrY:24644460-28352893)x0 copy number loss not provided [RCV000684436] ChrY:24644460..28352893 [GRCh37]
ChrY:Yq11.223-11.23		 uncertain significance
GRCh37/hg19 Yq11.223-11.23(chrY:24644460-28451874)x2 copy number gain not provided [RCV000684437] ChrY:24644460..28451874 [GRCh37]
ChrY:Yq11.223-11.23		 likely benign
GRCh37/hg19 Yq11.223-11.23(chrY:24663585-28799937)x0 copy number loss not provided [RCV000684438] ChrY:24663585..28799937 [GRCh37]
ChrY:Yq11.223-11.23		 pathogenic
GRCh37/hg19 Yq11.223-11.23(chrY:24073794-28799937)x0 copy number loss not provided [RCV000684440] ChrY:24073794..28799937 [GRCh37]
ChrY:Yq11.223-11.23		 pathogenic
GRCh37/hg19 Yq11.221-11.23(chrY:19574920-28423925)x2 copy number gain not provided [RCV000684441] ChrY:19574920..28423925 [GRCh37]
ChrY:Yq11.221-11.23		 likely benign
GRCh37/hg19 Yq11.21-12(chrY:13410538-59032808)x0 copy number loss not provided [RCV000684445] ChrY:13410538..59032808 [GRCh37]
ChrY:Yq11.21-12		 pathogenic
GRCh37/hg19 Yq11.223-11.23(chrY:24500602-28727063)x3 copy number gain not provided [RCV000754073] ChrY:24500602..28727063 [GRCh37]
ChrY:Yq11.223-11.23		 benign
GRCh37/hg19 Yq11.223-11.23(chrY:24522363-28701583)x3 copy number gain not provided [RCV000754075] ChrY:24522363..28701583 [GRCh37]
ChrY:Yq11.223-11.23		 benign
Single allele duplication Autism [RCV000754378] ChrY:1..57227415 [GRCh38]
ChrY:Yp11.32-q12		 likely pathogenic
GRCh37/hg19 Yq11.1-12(chrY:13132024-28817458)x0 copy number loss not provided [RCV000754010] ChrY:13132024..28817458 [GRCh37]
ChrY:Yq11.1-12		 pathogenic
GRCh37/hg19 Yp11.31-q11.23(chrY:2655180-28727063)x0 copy number gain not provided [RCV000753972] ChrY:2655180..28727063 [GRCh37]
ChrY:Yp11.31-q11.23		 pathogenic
GRCh37/hg19 Yp11.31-q12(chrY:2655180-58883690)x2 copy number gain not provided [RCV000753973] ChrY:2655180..58883690 [GRCh37]
ChrY:Yp11.31-q12		 pathogenic
GRCh37/hg19 Yq11.223-11.23(chrY:24522363-28727063)x3 copy number gain not provided [RCV000754076] ChrY:24522363..28727063 [GRCh37]
ChrY:Yq11.223-11.23		 benign
GRCh37/hg19 Yq11.223-11.23(chrY:24522363-28742675)x3 copy number gain not provided [RCV000754077] ChrY:24522363..28742675 [GRCh37]
ChrY:Yq11.223-11.23		 benign
GRCh37/hg19 Yq11.223-11.23(chrY:24461432-28701583)x3 copy number gain not provided [RCV000754071] ChrY:24461432..28701583 [GRCh37]
ChrY:Yq11.223-11.23		 benign
GRCh37/hg19 Yq11.223-11.23(chrY:24500602-28742675)x3 copy number gain not provided [RCV000754074] ChrY:24500602..28742675 [GRCh37]
ChrY:Yq11.223-11.23		 benign
GRCh37/hg19 Yq11.223-11.23(chrY:24461432-28742675)x3 copy number gain not provided [RCV000754072] ChrY:24461432..28742675 [GRCh37]
ChrY:Yq11.223-11.23		 benign
GRCh37/hg19 Yq11.223-12(chrY:24770884-59336737)x0 copy number loss not provided [RCV001007400] ChrY:24770884..59336737 [GRCh37]
ChrY:Yq11.223-12		 pathogenic
GRCh37/hg19 Yq11.223-11.23(chrY:24644460-28341390)x0 copy number loss Male infertility [RCV001090070] ChrY:24644460..28341390 [GRCh37]
ChrY:Yq11.223-11.23		 pathogenic
GRCh37/hg19 Yq11.223-11.23(chrY:24651462-28328263)x0 copy number loss Male infertility [RCV001090079] ChrY:24651462..28328263 [GRCh37]
ChrY:Yq11.223-11.23		 pathogenic
GRCh37/hg19 Yq11.223-11.23(chrY:24770884-28355431)x0 copy number loss Male infertility [RCV001090075] ChrY:24770884..28355431 [GRCh37]
ChrY:Yq11.223-11.23		 pathogenic
GRCh37/hg19 Yq11.221-11.23(chrY:18546605-28799937)x0 copy number loss Male infertility [RCV001090076] ChrY:18546605..28799937 [GRCh37]
ChrY:Yq11.221-11.23		 pathogenic
GRCh37/hg19 Yq11.221-12(chrY:16053146-59343488)x2 copy number gain not provided [RCV000848067] ChrY:16053146..59343488 [GRCh37]
ChrY:Yq11.221-12		 pathogenic
GRCh37/hg19 Yq11.221-12(chrY:15190336-59343488)x0 copy number loss not provided [RCV000847612] ChrY:15190336..59343488 [GRCh37]
ChrY:Yq11.221-12		 pathogenic
GRCh37/hg19 Yq11.222-11.23(chrY:21039792-28799937)x0 copy number loss not provided [RCV000847006] ChrY:21039792..28799937 [GRCh37]
ChrY:Yq11.222-11.23		 pathogenic
GRCh37/hg19 Yq11.222-12(chrY:21035530-59336737)x0 copy number loss not provided [RCV000845979] ChrY:21035530..59336737 [GRCh37]
ChrY:Yq11.222-12		 pathogenic
GRCh37/hg19 Yq11.23-12(chrY:26241299-59336737)x0 copy number loss not provided [RCV001007401] ChrY:26241299..59336737 [GRCh37]
ChrY:Yq11.23-12		 pathogenic
GRCh37/hg19 Yq11.223-11.23(chrY:23887108-28799937)x0 copy number loss Male infertility [RCV001090072] ChrY:23887108..28799937 [GRCh37]
ChrY:Yq11.223-11.23		 pathogenic
GRCh37/hg19 Yq11.222-11.23(chrY:20111978-28423925)x0 copy number loss Male infertility [RCV001090077] ChrY:20111978..28423925 [GRCh37]
ChrY:Yq11.222-11.23		 pathogenic
GRCh37/hg19 Yp11.32-q11.23(chrY:168546-28799937)x2 copy number gain not provided [RCV001007377] ChrY:168546..28799937 [GRCh37]
ChrY:Yp11.32-q11.23		 pathogenic
GRCh37/hg19 Yq11.223-11.23(chrY:24644460-28423925)x2 copy number gain not provided [RCV001007399] ChrY:24644460..28423925 [GRCh37]
ChrY:Yq11.223-11.23		 likely benign
GRCh37/hg19 Yq11.221-11.23(chrY:19567361-28458663)x2 copy number gain not provided [RCV001007396] ChrY:19567361..28458663 [GRCh37]
ChrY:Yq11.221-11.23		 likely benign
GRCh37/hg19 Yq11.222-11.23(chrY:21719615-28799937)x0 copy number loss Male infertility [RCV001090083] ChrY:21719615..28799937 [GRCh37]
ChrY:Yq11.222-11.23		 pathogenic
GRCh37/hg19 Yq11.21-11.23(chrY:13800703-28799937)x0 copy number loss Male infertility [RCV001090084] ChrY:13800703..28799937 [GRCh37]
ChrY:Yq11.21-11.23		 pathogenic
GRCh37/hg19 Yq11.222-11.23(chrY:20608554-28799937)x0 copy number loss Male infertility [RCV001090069] ChrY:20608554..28799937 [GRCh37]
ChrY:Yq11.222-11.23		 pathogenic
GRCh37/hg19 Yq11.221-11.23(chrY:15427283-28799937)x0 copy number loss Male infertility [RCV001090085] ChrY:15427283..28799937 [GRCh37]
ChrY:Yq11.221-11.23		 pathogenic
GRCh37/hg19 Yq11.223-11.23(chrY:25403868-27224389)x0 copy number loss not provided [RCV001258430] ChrY:25403868..27224389 [GRCh37]
ChrY:Yq11.223-11.23		 uncertain significance
GRCh37/hg19 Yq11.23(chrY:26241372-27698929)x0 copy number loss not provided [RCV001834429] ChrY:26241372..27698929 [GRCh37]
ChrY:Yq11.23		 uncertain significance
GRCh37/hg19 Yq11.223-11.23(chrY:24770885-28410810)x0 copy number loss not provided [RCV001834172] ChrY:24770885..28410810 [GRCh37]
ChrY:Yq11.223-11.23		 uncertain significance
GRCh37/hg19 Yp11.31-q11.23(chrY:2650424-28799654) copy number loss not provided [RCV002221453] ChrY:2650424..28799654 [GRCh37]
ChrY:Yp11.31-q11.23		 pathogenic
GRCh37/hg19 Yq11.21-11.23(chrY:13905421-28799654) copy number loss not provided [RCV002221454] ChrY:13905421..28799654 [GRCh37]
ChrY:Yq11.21-11.23		 pathogenic
GRCh37/hg19 Yp11.32-q12(chrY:1-59373566) copy number gain Global developmental delay [RCV002280747] ChrY:1..59373566 [GRCh37]
ChrY:Yp11.32-q12		 pathogenic
GRCh37/hg19 Yq11.223-11.23(chrY:25856867-28113239)x2 copy number gain Autism [RCV002286333] ChrY:25856867..28113239 [GRCh37]
ChrY:Yq11.223-11.23		 uncertain significance
GRCh37/hg19 Yq11.223-11.23(chrY:24985375-28458663)x2 copy number gain See cases [RCV002286334] ChrY:24985375..28458663 [GRCh37]
ChrY:Yq11.223-11.23		 uncertain significance
GRCh37/hg19 Yq11.223-11.23(chrY:25856644-27811846)x2 copy number gain See cases [RCV002292207] ChrY:25856644..27811846 [GRCh37]
ChrY:Yq11.223-11.23		 uncertain significance
GRCh37/hg19 Yq11.221-12(chrY:16203971-59336737)x0 copy number loss not provided [RCV002474928] ChrY:16203971..59336737 [GRCh37]
ChrY:Yq11.221-12		 uncertain significance
GRCh37/hg19 Yq11.223-11.23(chrY:24644461-28341390)x1 copy number loss not provided [RCV002472673] ChrY:24644461..28341390 [GRCh37]
ChrY:Yq11.223-11.23		 uncertain significance
GRCh37/hg19 Yq11.23(chrY:26412661-27436689)x0 copy number loss not provided [RCV002474889] ChrY:26412661..27436689 [GRCh37]
ChrY:Yq11.23		 uncertain significance
GRCh37/hg19 Yq11.21-12(chrY:14370813-59373566)x0 copy number loss not provided [RCV002473934] ChrY:14370813..59373566 [GRCh37]
ChrY:Yq11.21-12		 pathogenic
GRCh37/hg19 Yq11.223-11.23(chrY:25726545-28231661)x0 copy number loss not provided [RCV003482950] ChrY:25726545..28231661 [GRCh37]
ChrY:Yq11.223-11.23		 uncertain significance
GRCh37/hg19 Yq11.221-11.23(chrY:18921311-28799937)x0 copy number loss not provided [RCV003482939] ChrY:18921311..28799937 [GRCh37]
ChrY:Yq11.221-11.23		 pathogenic
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:84
Count of miRNA genes:82
Interacting mature miRNAs:83
Transcripts:ENST00000420149
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system exocrine system hemolymphoid system hepatobiliary system renal system reproductive system
High
Medium
Low
Below cutoff 7 7 2 7 11 10

Sequence


Reference Sequences
RefSeq Acc Id: ENST00000420149
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 EnsemblY24,570,202 - 24,607,025 (+)Ensembl
RefSeq Acc Id: NR_002178
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38Y24,570,202 - 24,607,025 (+)NCBI
GRCh37Y26,716,349 - 26,753,172 (+)RGD
Build 36Y25,125,737 - 25,162,560 (+)NCBI Archive
HuRefY17,892,011 - 17,901,668 (+)ENTREZGENE
T2T-CHM13v2.0Y24,255,525 - 24,292,324 (-)NCBI
Sequence:

Additional Information

Database Acc Id Source(s)
COSMIC TTTY4B COSMIC
Ensembl Genes ENSG00000235412 Ensembl, ENTREZGENE
Ensembl Transcript ENST00000420149 ENTREZGENE
GTEx ENSG00000235412 GTEx
HGNC ID HGNC:31891 ENTREZGENE
Human Proteome Map TTTY4B Human Proteome Map
NCBI Gene 474149 ENTREZGENE
PharmGKB PA134861789 PharmGKB
RNAcentral URS000060599D RNACentral


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-07-10 TTTY4B  testis expressed transcript, Y-linked 4B  TTTY4B  testis-specific transcript, Y-linked 4B  Symbol and/or name change 19259463 PROVISIONAL
2018-05-22 TTTY4B  testis-specific transcript, Y-linked 4B    testis-specific transcript, Y-linked 4B (non-protein coding)  Symbol and/or name change 5135510 APPROVED
2011-09-01 TTTY4B  testis-specific transcript, Y-linked 4B (non-protein coding)  TTTY4B  testis-specific transcript, Y-linked 4B (non-protein coding)  Symbol and/or name change 5135510 APPROVED