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Gene: TNRC6B (trinucleotide repeat containing adaptor 6B) Homo sapiens
Symbol: TNRC6B
Name: trinucleotide repeat containing adaptor 6B
Description: Exhibits RNA binding activity. Involved in gene silencing by RNA and positive regulation of nuclear-transcribed mRNA poly(A) tail shortening. Predicted to localize to P-body and nucleoplasm. Implicated in subserous uterine fibroid and uterine fibroid; PARTICIPATES IN microRNA pathway; INTERACTS WITH (-)-epigallocatechin 3-gallate; 3-isobutyl-1-methyl-7H-xanthine; aflatoxin B1.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: KIAA1093; trinucleotide repeat containing 6B; trinucleotide repeat-containing gene 6B protein
Mus musculus (house mouse) : Tnrc6b (trinucleotide repeat containing 6b)  MGI  Alliance
Rattus norvegicus (Norway rat) : Tnrc6b (trinucleotide repeat containing adaptor 6B)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tnrc6b (trinucleotide repeat containing adaptor 6B)
Pan paniscus (bonobo/pygmy chimpanzee) : TNRC6B (trinucleotide repeat containing adaptor 6B)
Canis lupus familiaris (dog) : TNRC6B (trinucleotide repeat containing adaptor 6B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tnrc6b (trinucleotide repeat containing adaptor 6B)
Sus scrofa (pig) : TNRC6B (trinucleotide repeat containing adaptor 6B)
Chlorocebus sabaeus (African green monkey) : TNRC6B (trinucleotide repeat containing adaptor 6B)
Heterocephalus glaber (naked mole-rat) : Tnrc6b (trinucleotide repeat containing adaptor 6B)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl2240,044,817 - 40,335,808 (+)EnsemblGRCh38hg38GRCh38
GRCh382240,044,817 - 40,335,808 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372240,440,046 - 40,731,812 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362238,770,767 - 39,061,758 (+)NCBINCBI36hg18NCBI36
Build 342238,898,445 - 39,043,860NCBI
Celera2224,242,863 - 24,533,872 (+)NCBI
Cytogenetic Map22q13.1NCBI
HuRef2223,404,077 - 23,694,839 (+)NCBIHuRef
CHM1_12240,400,124 - 40,690,692 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on TNRC6B
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1350349
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-08-04
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.