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Gene: PARP8 (poly(ADP-ribose) polymerase family member 8) Homo sapiens
Symbol: PARP8
Name: poly(ADP-ribose) polymerase family member 8
Description: Exhibits protein ADP-ribosylase activity. Involved in protein auto-ADP-ribosylation and protein mono-ADP-ribosylation. Predicted to localize to endoplasmic reticulum tubular network and nuclear envelope; PARTICIPATES IN ADP-ribosylation pathway, mono and poly-ribosylation; INTERACTS WITH (-)-epigallocatechin 3-gallate; aflatoxin B1; antirheumatic drug.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: ADP-ribosyltransferase diphtheria toxin-like 16; ARTD16; FLJ21308; MGC42864; pART16; poly (ADP-ribose) polymerase family, member 8; poly [ADP-ribose] polymerase 8
Mus musculus (house mouse) : Parp8 (poly (ADP-ribose) polymerase family, member 8)  MGI  Alliance
Rattus norvegicus (Norway rat) : Parp8 (poly (ADP-ribose) polymerase family, member 8)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Parp8 (poly(ADP-ribose) polymerase family member 8)
Pan paniscus (bonobo/pygmy chimpanzee) : PARP8 (poly(ADP-ribose) polymerase family member 8)
Canis lupus familiaris (dog) : PARP8 (poly(ADP-ribose) polymerase family member 8)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Parp8 (poly(ADP-ribose) polymerase family member 8)
Sus scrofa (pig) : PARP8 (poly(ADP-ribose) polymerase family member 8)
Chlorocebus sabaeus (African green monkey) : PARP8 (poly(ADP-ribose) polymerase family member 8)
Heterocephalus glaber (naked mole-rat) : Parp8 (poly(ADP-ribose) polymerase family member 8)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl550,665,899 - 50,846,519 (+)EnsemblGRCh38hg38GRCh38
GRCh38550,665,831 - 50,846,522 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37549,961,733 - 50,142,356 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36549,998,570 - 50,173,933 (+)NCBINCBI36hg18NCBI36
Build 34549,998,569 - 50,173,933NCBI
Celera546,908,424 - 47,088,865 (+)NCBI
Cytogenetic Map5q11.1NCBI
HuRef546,926,307 - 47,106,926 (+)NCBIHuRef
CHM1_1549,964,864 - 50,145,462 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on PARP8
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1350347
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-06-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.