Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: SH3PXD2B (SH3 and PX domains 2B) Homo sapiens
Analyze
Symbol: SH3PXD2B
Name: SH3 and PX domains 2B
Description: Predicted to have SH2 domain binding activity; phosphatidylinositol phosphate binding activity; and superoxide-generating NADPH oxidase activator activity. Involved in several processes, including animal organ development; extracellular matrix disassembly; and superoxide metabolic process. Predicted to localize to cytoplasm and podosome. Implicated in Frank-Ter Haar syndrome.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: adapter protein HOFI; adaptor protein HOFI; factor for adipocyte differentiation 49; FAD49; FLJ20831; FTHS; HOFI; KIAA1295; SH3 and PX domain-containing protein 2B; TKS4; TSK4; tyrosine kinase substrate with four SH3 domains
Orthologs:
Mus musculus (house mouse) : Sh3pxd2b (SH3 and PX domains 2B)  MGI  Alliance
Rattus norvegicus (Norway rat) : Sh3pxd2b (SH3 and PX domains 2B)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sh3pxd2b (SH3 and PX domains 2B)
Pan paniscus (bonobo/pygmy chimpanzee) : SH3PXD2B (SH3 and PX domains 2B)
Canis lupus familiaris (dog) : SH3PXD2B (SH3 and PX domains 2B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sh3pxd2b (SH3 and PX domains 2B)
Sus scrofa (pig) : SH3PXD2B (SH3 and PX domains 2B)
Chlorocebus sabaeus (African green monkey) : SH3PXD2B (SH3 and PX domains 2B)
Heterocephalus glaber (naked mole-rat) : Sh3pxd2b (SH3 and PX domains 2B)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl5172,325,000 - 172,454,525 (-)EnsemblGRCh38hg38GRCh38
GRCh385172,325,181 - 172,454,525 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh375171,752,185 - 171,881,527 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365171,693,108 - 171,814,132 (-)NCBINCBI36hg18NCBI36
Celera5167,792,626 - 167,913,367 (-)NCBI
Cytogenetic Map5q35.1NCBI
HuRef5166,855,971 - 166,956,421 (-)NCBIHuRef
CHM1_15171,185,216 - 171,314,268 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on SH3PXD2B
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1349978
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-06-18
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.