CUEDC1 (CUE domain containing 1) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: CUEDC1 (CUE domain containing 1) Homo sapiens
Analyze
Symbol: CUEDC1
Name: CUE domain containing 1
RGD ID: 1349850
HGNC Page HGNC:31350
Description: Predicted to enable ubiquitin binding activity.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: CUE domain-containing protein 1; DKFZp547L163; FLJ20739
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381757,861,243 - 57,955,412 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1757,861,243 - 57,955,412 (-)EnsemblGRCh38hg38GRCh38
GRCh371755,938,604 - 56,032,773 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361753,295,336 - 53,335,749 (-)NCBINCBI36Build 36hg18NCBI36
Build 341753,295,335 - 53,335,749NCBI
Celera1752,402,105 - 52,442,530 (-)NCBICelera
Cytogenetic Map17q22NCBI
HuRef1751,299,100 - 51,341,254 (-)NCBIHuRef
CHM1_11756,003,616 - 56,097,775 (-)NCBICHM1_1
T2T-CHM13v2.01758,734,503 - 58,828,695 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
References

References - curated
# Reference Title Reference Citation
1. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:12477932   PMID:14702039   PMID:15231748   PMID:15489334   PMID:19953087   PMID:20098747   PMID:20802204   PMID:20804422   PMID:24510904   PMID:25260751   PMID:26186194  
PMID:27578003   PMID:28190767   PMID:28514442   PMID:29117863   PMID:29467281   PMID:29513927   PMID:30021884   PMID:30145202   PMID:31527615   PMID:31699778   PMID:32296183   PMID:33067938  
PMID:33099540   PMID:33961781   PMID:34599178   PMID:35509820   PMID:35914814   PMID:36724073   PMID:36949045  


Genomics

Comparative Map Data
CUEDC1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381757,861,243 - 57,955,412 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1757,861,243 - 57,955,412 (-)EnsemblGRCh38hg38GRCh38
GRCh371755,938,604 - 56,032,773 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361753,295,336 - 53,335,749 (-)NCBINCBI36Build 36hg18NCBI36
Build 341753,295,335 - 53,335,749NCBI
Celera1752,402,105 - 52,442,530 (-)NCBICelera
Cytogenetic Map17q22NCBI
HuRef1751,299,100 - 51,341,254 (-)NCBIHuRef
CHM1_11756,003,616 - 56,097,775 (-)NCBICHM1_1
T2T-CHM13v2.01758,734,503 - 58,828,695 (-)NCBIT2T-CHM13v2.0
Cuedc1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391187,989,972 - 88,084,966 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1187,988,884 - 88,084,966 (+)EnsemblGRCm39 Ensembl
GRCm381188,099,146 - 88,194,140 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1188,098,058 - 88,194,140 (+)EnsemblGRCm38mm10GRCm38
MGSCv371187,912,648 - 88,007,642 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361187,915,444 - 88,009,110 (+)NCBIMGSCv36mm8
Celera1197,701,112 - 97,797,818 (+)NCBICelera
Cytogenetic Map11CNCBI
cM Map1152.4NCBI
Cuedc1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81073,389,798 - 73,484,914 (+)NCBIGRCr8
mRatBN7.21072,892,637 - 72,986,546 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1072,892,637 - 72,986,542 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1077,502,980 - 77,596,217 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01077,007,912 - 77,101,147 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01072,472,427 - 72,565,664 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01075,495,817 - 75,516,280 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1075,495,817 - 75,516,304 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01074,590,105 - 74,610,568 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41076,467,673 - 76,488,136 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11076,408,476 - 76,502,502 (+)NCBI
Celera1071,875,454 - 71,895,917 (+)NCBICelera
Cytogenetic Map10q26NCBI
Cuedc1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554515,105,123 - 5,120,544 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554515,054,633 - 5,124,318 (+)NCBIChiLan1.0ChiLan1.0
CUEDC1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21974,036,926 - 74,131,517 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11778,847,852 - 78,941,751 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01751,941,043 - 52,034,948 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11756,798,556 - 56,822,922 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1756,798,556 - 56,822,922 (-)Ensemblpanpan1.1panPan2
CUEDC1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1932,563,784 - 32,584,116 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl932,565,314 - 32,584,207 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha931,802,497 - 31,822,902 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0933,372,124 - 33,392,522 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl933,373,654 - 33,392,839 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1932,156,619 - 32,177,007 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0932,439,876 - 32,460,268 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0932,523,497 - 32,543,899 (-)NCBIUU_Cfam_GSD_1.0
Cuedc1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560231,892,522 - 31,954,782 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364905,175,058 - 5,182,521 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364905,120,268 - 5,182,523 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CUEDC1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1234,141,649 - 34,167,930 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11234,141,649 - 34,167,731 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21234,964,028 - 35,053,237 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CUEDC1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11635,444,405 - 35,550,666 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660776,261,263 - 6,355,720 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cuedc1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462479512,743,174 - 12,774,273 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462479512,743,634 - 12,823,711 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in CUEDC1
7 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 17q23.2-25.3(chr17:36449220-83086677)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052483]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052483]|See cases [RCV000052483] Chr17:36449220..83086677 [GRCh38]
Chr17:58617905..81044553 [GRCh37]
Chr17:55972687..78637842 [NCBI36]
Chr17:17q23.2-25.3		 pathogenic
GRCh38/hg38 17q21.33-24.2(chr17:36449220-68170214)x3 copy number gain See cases [RCV000050957] Chr17:36449220..68170214 [GRCh38]
Chr17:48563237..65936105 [GRCh37]
Chr17:45918236..63677950 [NCBI36]
Chr17:17q21.33-24.2		 pathogenic
GRCh38/hg38 17q22(chr17:56958745-58171125)x1 copy number loss See cases [RCV000053434] Chr17:56958745..58171125 [GRCh38]
Chr17:55036106..56248486 [GRCh37]
Chr17:52391105..53603485 [NCBI36]
Chr17:17q22		 pathogenic
NM_001271875.1(CUEDC1):c.1102T>C (p.Phe368Leu) single nucleotide variant Malignant melanoma [RCV000063260] Chr17:57866536 [GRCh38]
Chr17:55943897 [GRCh37]
Chr17:53298896 [NCBI36]
Chr17:17q22		 not provided
NM_001271875.1(CUEDC1):c.1101C>T (p.Asp367=) single nucleotide variant Malignant melanoma [RCV000063261] Chr17:57866537 [GRCh38]
Chr17:55943898 [GRCh37]
Chr17:53298897 [NCBI36]
Chr17:17q22		 not provided
NM_001271875.1(CUEDC1):c.471C>T (p.Asp157=) single nucleotide variant Malignant melanoma [RCV000071578] Chr17:57873711 [GRCh38]
Chr17:55951072 [GRCh37]
Chr17:53306071 [NCBI36]
Chr17:17q22		 not provided
NM_001271875.1(CUEDC1):c.-315-2725G>T single nucleotide variant Lung cancer [RCV000100568] Chr17:57888604 [GRCh38]
Chr17:55965965 [GRCh37]
Chr17:17q22		 uncertain significance
GRCh38/hg38 17q23.1-25.1(chr17:36449220-75053130)x3 copy number gain See cases [RCV000137437] Chr17:36449220..75053130 [GRCh38]
Chr17:57595736..73049225 [GRCh37]
Chr17:54950518..70560820 [NCBI36]
Chr17:17q23.1-25.1		 pathogenic
GRCh38/hg38 17q22(chr17:56683505-58084939)x1 copy number loss See cases [RCV000135409] Chr17:56683505..58084939 [GRCh38]
Chr17:54760866..56162300 [GRCh37]
Chr17:52115865..53517299 [NCBI36]
Chr17:17q22		 pathogenic
GRCh38/hg38 17q22-23.1(chr17:57418806-59735464)x1 copy number loss See cases [RCV000140211] Chr17:57418806..59735464 [GRCh38]
Chr17:55496167..57812825 [GRCh37]
Chr17:52851166..55167607 [NCBI36]
Chr17:17q22-23.1		 pathogenic
GRCh37/hg19 17q22(chr17:55916829-56770618)x1 copy number loss See cases [RCV000239996] Chr17:55916829..56770618 [GRCh37]
Chr17:17q22		 likely pathogenic
GRCh37/hg19 17q22(chr17:52189051-57477162)x3 copy number gain See cases [RCV000448801] Chr17:52189051..57477162 [GRCh37]
Chr17:17q22		 pathogenic
GRCh37/hg19 17q21.33-23.2(chr17:49076980-58740945)x3 copy number gain See cases [RCV000448805] Chr17:49076980..58740945 [GRCh37]
Chr17:17q21.33-23.2		 pathogenic
GRCh37/hg19 17q21.31-25.3(chr17:42580684-81085615)x3 copy number gain See cases [RCV000447823] Chr17:42580684..81085615 [GRCh37]
Chr17:17q21.31-25.3		 pathogenic
GRCh37/hg19 17p13.3-q25.3(chr17:526-81041938) copy number gain See cases [RCV000511439] Chr17:526..81041938 [GRCh37]
Chr17:17p13.3-q25.3		 pathogenic
GRCh37/hg19 17p13.3-q25.3(chr17:526-81041938)x3 copy number gain See cases [RCV000512441] Chr17:526..81041938 [GRCh37]
Chr17:17p13.3-q25.3		 pathogenic
GRCh37/hg19 17p13.3-q25.3(chr17:8547-81060040)x3 copy number gain not provided [RCV000739324] Chr17:8547..81060040 [GRCh37]
Chr17:17p13.3-q25.3		 pathogenic
GRCh37/hg19 17p13.3-q25.3(chr17:7214-81058310)x3 copy number gain not provided [RCV000739320] Chr17:7214..81058310 [GRCh37]
Chr17:17p13.3-q25.3		 pathogenic
GRCh37/hg19 17p13.3-q25.3(chr17:12344-81057996)x3 copy number gain not provided [RCV000739325] Chr17:12344..81057996 [GRCh37]
Chr17:17p13.3-q25.3		 pathogenic
GRCh37/hg19 17q22(chr17:55840956-56090386)x1 copy number loss not provided [RCV001795838] Chr17:55840956..56090386 [GRCh37]
Chr17:17q22		 uncertain significance
NC_000017.10:g.(?_54671585)_(59938900_?)dup duplication Familial aplasia of the vermis [RCV001923071] Chr17:54671585..59938900 [GRCh37]
Chr17:17q22-23.2		 uncertain significance
NC_000017.10:g.(?_55442363)_(56309063_?)del deletion Intellectual disability [RCV003151461] Chr17:55442363..56309063 [GRCh37]
Chr17:17q22		 pathogenic
NC_000017.10:g.(?_55806534)_(56540597_?)del deletion Intellectual disability [RCV003151464] Chr17:55806534..56540597 [GRCh37]
Chr17:17q22		 pathogenic
GRCh37/hg19 17q22(chr17:55043662-56728123)x1 copy number loss See cases [RCV002292214] Chr17:55043662..56728123 [GRCh37]
Chr17:17q22		 pathogenic
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:5016
Count of miRNA genes:943
Interacting mature miRNAs:1154
Transcripts:ENST00000360238, ENST00000407144, ENST00000577422, ENST00000577497, ENST00000577589, ENST00000577830, ENST00000577840, ENST00000578357, ENST00000581391, ENST00000581898, ENST00000582951, ENST00000584746, ENST00000585294
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
RH12609  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371755,940,392 - 55,940,560UniSTSGRCh37
Build 361753,295,391 - 53,295,559RGDNCBI36
Celera1752,402,160 - 52,402,328RGD
Cytogenetic Map17q23.2UniSTS
HuRef1751,300,888 - 51,301,056UniSTS
GeneMap99-GB4 RH Map17369.34UniSTS
A004X25  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371755,940,363 - 55,940,481UniSTSGRCh37
Build 361753,295,362 - 53,295,480RGDNCBI36
Celera1752,402,131 - 52,402,249RGD
Cytogenetic Map17q23.2UniSTS
HuRef1751,300,859 - 51,300,977UniSTS
GeneMap99-GB4 RH Map17366.86UniSTS
Whitehead-RH Map17419.3UniSTS
G17969  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371755,961,366 - 55,961,510UniSTSGRCh37
Build 361753,316,365 - 53,316,509RGDNCBI36
Celera1752,423,144 - 52,423,288RGD
Cytogenetic Map17q23.2UniSTS
HuRef1751,321,859 - 51,322,003UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 2214 2252 1324 235 492 77 3840 2086 3256 370 1019 1580 171 1171 2672 1
Low 224 724 399 389 1119 388 516 110 477 49 440 31 4 1 33 116 5 2
Below cutoff 1 7 3 278 1 1 1 2

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001271875 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001292025 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011524812 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017024640 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017024641 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047436060 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054316111 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054316112 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054316113 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001752509 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_008484819 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_008484820 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_934459 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_934460 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC015813 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC015845 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK000746 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK000977 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC056882 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BG475111 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BU732837 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471109 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068261 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CR627470 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000360238   ⟹   ENSP00000353373
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1757,862,976 - 57,903,389 (-)Ensembl
RefSeq Acc Id: ENST00000407144   ⟹   ENSP00000384712
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1757,862,696 - 57,892,688 (-)Ensembl
RefSeq Acc Id: ENST00000577422
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1757,862,875 - 57,867,305 (-)Ensembl
RefSeq Acc Id: ENST00000577497
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1757,862,963 - 57,866,857 (-)Ensembl
RefSeq Acc Id: ENST00000577589   ⟹   ENSP00000462789
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1757,872,811 - 57,885,837 (-)Ensembl
RefSeq Acc Id: ENST00000577830   ⟹   ENSP00000462717
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1757,861,243 - 57,955,412 (-)Ensembl
RefSeq Acc Id: ENST00000577840   ⟹   ENSP00000463666
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1757,863,272 - 57,955,257 (-)Ensembl
RefSeq Acc Id: ENST00000578357
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1757,862,963 - 57,869,938 (-)Ensembl
RefSeq Acc Id: ENST00000581391
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1757,862,875 - 57,868,465 (-)Ensembl
RefSeq Acc Id: ENST00000581898   ⟹   ENSP00000462045
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1757,862,963 - 57,872,670 (-)Ensembl
RefSeq Acc Id: ENST00000582951
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1757,862,875 - 57,867,630 (-)Ensembl
RefSeq Acc Id: ENST00000584746
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1757,861,604 - 57,871,365 (-)Ensembl
RefSeq Acc Id: ENST00000585294   ⟹   ENSP00000462177
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1757,862,976 - 57,867,415 (-)Ensembl
RefSeq Acc Id: NM_001271875   ⟹   NP_001258804
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381757,861,243 - 57,955,412 (-)NCBI
HuRef1751,299,100 - 51,341,254 (-)NCBI
CHM1_11756,003,616 - 56,097,775 (-)NCBI
T2T-CHM13v2.01758,734,503 - 58,828,695 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001292025   ⟹   NP_001278954
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381757,861,243 - 57,903,389 (-)NCBI
CHM1_11756,003,616 - 56,045,835 (-)NCBI
T2T-CHM13v2.01758,734,503 - 58,776,672 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011524812   ⟹   XP_011523114
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381757,861,243 - 57,885,260 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017024641   ⟹   XP_016880130
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381757,861,243 - 57,955,412 (-)NCBI
Sequence:
RefSeq Acc Id: XM_047436060   ⟹   XP_047292016
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381757,861,243 - 57,946,892 (-)NCBI
RefSeq Acc Id: XM_054316111   ⟹   XP_054172086
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01758,734,503 - 58,823,477 (-)NCBI
RefSeq Acc Id: XM_054316112   ⟹   XP_054172087
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01758,734,503 - 58,828,695 (-)NCBI
RefSeq Acc Id: XM_054316113   ⟹   XP_054172088
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01758,734,503 - 58,758,529 (-)NCBI
RefSeq Acc Id: XR_008484819
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01758,734,503 - 58,828,695 (-)NCBI
RefSeq Acc Id: XR_008484820
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01758,739,734 - 58,828,695 (-)NCBI
RefSeq Acc Id: XR_934459
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381757,861,243 - 57,955,412 (-)NCBI
Sequence:
RefSeq Acc Id: XR_934460
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381757,866,474 - 57,955,412 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_001258804   ⟸   NM_001271875
- UniProtKB: D3DTZ2 (UniProtKB/Swiss-Prot),   Q9NWD0 (UniProtKB/Swiss-Prot),   Q9NWM3 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001278954   ⟸   NM_001292025
- UniProtKB: D3DTZ2 (UniProtKB/Swiss-Prot),   Q9NWD0 (UniProtKB/Swiss-Prot),   Q9NWM3 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_011523114   ⟸   XM_011524812
- Peptide Label: isoform X3
- UniProtKB: J3QLQ8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_016880130   ⟸   XM_017024641
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSP00000462045   ⟸   ENST00000581898
RefSeq Acc Id: ENSP00000353373   ⟸   ENST00000360238
RefSeq Acc Id: ENSP00000462177   ⟸   ENST00000585294
RefSeq Acc Id: ENSP00000463666   ⟸   ENST00000577840
RefSeq Acc Id: ENSP00000462717   ⟸   ENST00000577830
RefSeq Acc Id: ENSP00000462789   ⟸   ENST00000577589
RefSeq Acc Id: ENSP00000384712   ⟸   ENST00000407144
RefSeq Acc Id: XP_047292016   ⟸   XM_047436060
- Peptide Label: isoform X1
- UniProtKB: Q9NWM3 (UniProtKB/Swiss-Prot),   D3DTZ2 (UniProtKB/Swiss-Prot),   Q9NWD0 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_054172087   ⟸   XM_054316112
- Peptide Label: isoform X2
RefSeq Acc Id: XP_054172086   ⟸   XM_054316111
- Peptide Label: isoform X1
- UniProtKB: Q9NWM3 (UniProtKB/Swiss-Prot),   D3DTZ2 (UniProtKB/Swiss-Prot),   Q9NWD0 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_054172088   ⟸   XM_054316113
- Peptide Label: isoform X3
Protein Domains
CUE

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9NWM3-F1-model_v2 AlphaFold Q9NWM3 1-386 view protein structure

Promoters
RGD ID:6793898
Promoter ID:HG_KWN:26662
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Lymphoblastoid,   NB4
Transcripts:NM_017949
Position:
Human AssemblyChrPosition (strand)Source
Build 361753,335,306 - 53,335,857 (-)MPROMDB
RGD ID:7235775
Promoter ID:EPDNEW_H23632
Type:initiation region
Name:CUEDC1_2
Description:CUE domain containing 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H23633  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381757,955,273 - 57,955,333EPDNEW
RGD ID:7235773
Promoter ID:EPDNEW_H23633
Type:initiation region
Name:CUEDC1_1
Description:CUE domain containing 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H23632  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381757,955,412 - 57,955,472EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:31350 AgrOrtholog
COSMIC CUEDC1 COSMIC
Ensembl Genes ENSG00000180891 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000360238 ENTREZGENE
  ENST00000360238.6 UniProtKB/Swiss-Prot
  ENST00000407144.6 UniProtKB/Swiss-Prot
  ENST00000577589.1 UniProtKB/TrEMBL
  ENST00000577830 ENTREZGENE
  ENST00000577830.6 UniProtKB/Swiss-Prot
  ENST00000577840 ENTREZGENE
  ENST00000577840.5 UniProtKB/TrEMBL
  ENST00000581898.5 UniProtKB/TrEMBL
  ENST00000585294.5 UniProtKB/TrEMBL
Gene3D-CATH DNA helicase RuvA subunit, C-terminal domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000180891 GTEx
HGNC ID HGNC:31350 ENTREZGENE
Human Proteome Map CUEDC1 Human Proteome Map
InterPro CUE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CUE_CUED1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CUEDC1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  UBA-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:404093 UniProtKB/Swiss-Prot
NCBI Gene 404093 ENTREZGENE
OMIM 620552 OMIM
PANTHER CUE DOMAIN-CONTAINING PROTEIN 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR13467 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam CUE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA134913154 PharmGKB
PROSITE CUE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART CUE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF46934 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt CUED1_HUMAN UniProtKB/Swiss-Prot
  D3DTZ2 ENTREZGENE
  J3KRK6_HUMAN UniProtKB/TrEMBL
  J3KRV3_HUMAN UniProtKB/TrEMBL
  J3KT42_HUMAN UniProtKB/TrEMBL
  J3QLQ8 ENTREZGENE, UniProtKB/TrEMBL
  L0R845_HUMAN UniProtKB/TrEMBL
  Q6AHX0_HUMAN UniProtKB/TrEMBL
  Q9NWD0 ENTREZGENE
  Q9NWM3 ENTREZGENE
UniProt Secondary D3DTZ2 UniProtKB/Swiss-Prot
  Q9NWD0 UniProtKB/Swiss-Prot