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Gene: MSLN (mesothelin) Homo sapiens
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Symbol: MSLN
Name: mesothelin
Description: Predicted to be involved in cell-matrix adhesion. Predicted to localize to the cell surface. Implicated in ovarian cancer; pancreas disease; pancreatic cancer; and pancreatic ductal carcinoma. Biomarker of bile duct carcinoma; common bile duct neoplasm; pancreatic cancer; and pancreatic ductal carcinoma.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CAK1; CAK1 antigen; megakaryocyte potentiating factor; MPF; pre-pro-megakaryocyte-potentiating factor; SMR; SMRP; soluble MPF mesothelin related protein
Orthologs:
Mus musculus (house mouse) : Msln (mesothelin)  MGI  Alliance
Rattus norvegicus (Norway rat) : Msln (mesothelin)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : MSLN (mesothelin)
Canis lupus familiaris (dog) : LOC611363 (mesothelin)
Sus scrofa (pig) : LOC100524016 (mesothelin)
Chlorocebus sabaeus (green monkey) : MSLN (mesothelin)
Heterocephalus glaber (naked mole-rat) : Msln (mesothelin)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl16760,734 - 768,865 (+)Ensembl
GRCh3816760,734 - 768,865 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3716810,765 - 818,865 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3616751,134 - 758,866 (+)NCBINCBI36hg18NCBI36
Build 3416750,797 - 758,866NCBI
Celera161,010,640 - 1,018,740 (+)NCBI
Cytogenetic Map16p13.3NCBI
HuRef16732,923 - 740,842 (+)NCBIHuRef
CHM1_116810,267 - 818,805 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on MSLN
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1349818
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-02-11
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.