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Gene: SPESP1 (sperm equatorial segment protein 1) Homo sapiens
Symbol: SPESP1
Name: sperm equatorial segment protein 1
Description: The encoded protein is a human alloantigen involved in sperm-egg binding and fusion. [provided by RefSeq, Apr 2010]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: equatorial segment protein; ESP; glycosylated 38 kDa sperm protein C-7/8; MGC24663; SP-ESP
Mus musculus (house mouse) : Spesp1 (sperm equatorial segment protein 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Spesp1 (sperm equatorial segment protein 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Spesp1 (sperm equatorial segment protein 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SPESP1 (sperm equatorial segment protein 1)
Canis lupus familiaris (dog) : SPESP1 (sperm equatorial segment protein 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Spesp1 (sperm equatorial segment protein 1)
Sus scrofa (pig) : SPESP1 (sperm equatorial segment protein 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh381568,930,500 - 68,946,811 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371569,222,839 - 69,239,150 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361567,009,919 - 67,026,202 (+)NCBINCBI36hg18NCBI36
Build 341567,009,918 - 67,026,202NCBI
Celera1546,111,968 - 46,128,285 (+)NCBI
Cytogenetic Map15q23NCBI
HuRef1546,055,769 - 46,072,086 (+)NCBIHuRef
CHM1_11569,340,923 - 69,357,240 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on SPESP1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1349587
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-06-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.