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Gene: INPP5J (inositol polyphosphate-5-phosphatase J) Homo sapiens
Symbol: INPP5J
Name: inositol polyphosphate-5-phosphatase J
Description: Predicted to have phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity and phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity. Predicted to be involved in inositol phosphate dephosphorylation; negative regulation of peptidyl-serine phosphorylation; and phosphatidylinositol dephosphorylation. Localizes to cytoplasm and ruffle; PARTICIPATES IN inositol metabolic pathway; inositol phosphate metabolic pathway; phosphatidylinositol 3-kinase signaling pathway; INTERACTS WITH 5-aza-2'-deoxycytidine; benzo[a]pyrene; cisplatin.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: inositol polyphosphate 5-phosphatase J; INPP5; MGC129984; phosphatidylinositol (4,5) bisphosphate 5-phosphatase, A; phosphatidylinositol 4,5-bisphosphate 5-phosphatase A; PIB5PA; PIPP
Mus musculus (house mouse) : Inpp5j (inositol polyphosphate 5-phosphatase J)  MGI  Alliance
Rattus norvegicus (Norway rat) : Inpp5j (inositol polyphosphate-5-phosphatase J)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Inpp5j (inositol polyphosphate-5-phosphatase J)
Pan paniscus (bonobo/pygmy chimpanzee) : INPP5J (inositol polyphosphate-5-phosphatase J)
Canis lupus familiaris (dog) : INPP5J (inositol polyphosphate-5-phosphatase J)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Inpp5j (inositol polyphosphate-5-phosphatase J)
Sus scrofa (pig) : INPP5J (inositol polyphosphate-5-phosphatase J)
Chlorocebus sabaeus (African green monkey) : INPP5J (inositol polyphosphate-5-phosphatase J)
Heterocephalus glaber (naked mole-rat) : Inpp5j (inositol polyphosphate-5-phosphatase J)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl2231,122,731 - 31,134,697 (+)EnsemblGRCh38hg38GRCh38
GRCh382231,107,736 - 31,134,697 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372231,518,893 - 31,530,683 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362229,848,961 - 29,860,683 (+)NCBINCBI36hg18NCBI36
Build 342229,843,514 - 29,855,236NCBI
Celera2215,319,037 - 15,330,758 (+)NCBI
Cytogenetic Map22q12.2NCBI
HuRef2214,480,700 - 14,492,341 (+)NCBIHuRef
CHM1_12231,478,771 - 31,490,548 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on INPP5J
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1349321
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-08-04
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.