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Gene: TSPAN16 (tetraspanin 16) Homo sapiens
Symbol: TSPAN16
Name: tetraspanin 16
Description: The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein might couple to signal transduction pathways and possibly modulate cellular activation and adhesion in haemopoietic and neural tissue. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: tetraspanin TM4-B; tetraspanin-16; TM-8; TM4-B; TM4SF16; transmembrane 4 superfamily member 16; tspan-16
Chinchilla lanigera (long-tailed chinchilla) : Tspan16 (tetraspanin 16)
Pan paniscus (bonobo/pygmy chimpanzee) : TSPAN16 (tetraspanin 16)
Canis lupus familiaris (dog) : TSPAN16 (tetraspanin 16)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tspan16 (tetraspanin 16)
Sus scrofa (pig) : TSPAN16 (tetraspanin 16)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh381911,296,144 - 11,326,996 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371911,406,798 - 11,437,672 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361911,267,824 - 11,298,672 (+)NCBINCBI36hg18NCBI36
Build 341911,267,823 - 11,298,672NCBI
Celera1911,301,683 - 11,332,546 (+)NCBI
Cytogenetic Map19p13.2NCBI
HuRef1910,982,809 - 11,013,654 (+)NCBIHuRef
CHM1_11911,407,839 - 11,438,699 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on TSPAN16
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1349307
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-09-12
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.