ZNF485 (zinc finger protein 485) - Rat Genome Database

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Gene: ZNF485 (zinc finger protein 485) Homo sapiens
Analyze
Symbol: ZNF485
Name: zinc finger protein 485
RGD ID: 1349192
HGNC Page HGNC:23440
Description: Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Zinc finger protein 93 (Zinc finger protein HTF34)
RGD Orthologs
Bonobo
Dog
Squirrel
Green Monkey
Alliance Genes
More Info more info ...
Related Pseudogenes: LOC100419802  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381043,606,438 - 43,617,904 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1043,606,419 - 43,617,904 (+)EnsemblGRCh38hg38GRCh38
GRCh371044,101,886 - 44,113,352 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361043,421,881 - 43,433,358 (+)NCBINCBI36Build 36hg18NCBI36
Build 341043,421,880 - 43,433,357NCBI
Celera1040,105,491 - 40,116,988 (+)NCBICelera
Cytogenetic Map10q11.21NCBI
HuRef1040,628,860 - 40,640,357 (+)NCBIHuRef
CHM1_11044,141,490 - 44,152,987 (+)NCBICHM1_1
T2T-CHM13v2.01044,487,360 - 44,498,826 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleus  (IBA,IEA)

References

References - curated
# Reference Title Reference Citation
1. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:14702039   PMID:15164054   PMID:15489334   PMID:16385451   PMID:21873635   PMID:29180619   PMID:32296183   PMID:33961781   PMID:35140242   PMID:35563538  


Genomics

Comparative Map Data
ZNF485
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381043,606,438 - 43,617,904 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1043,606,419 - 43,617,904 (+)EnsemblGRCh38hg38GRCh38
GRCh371044,101,886 - 44,113,352 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361043,421,881 - 43,433,358 (+)NCBINCBI36Build 36hg18NCBI36
Build 341043,421,880 - 43,433,357NCBI
Celera1040,105,491 - 40,116,988 (+)NCBICelera
Cytogenetic Map10q11.21NCBI
HuRef1040,628,860 - 40,640,357 (+)NCBIHuRef
CHM1_11044,141,490 - 44,152,987 (+)NCBICHM1_1
T2T-CHM13v2.01044,487,360 - 44,498,826 (+)NCBIT2T-CHM13v2.0
ZNF485
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2856,326,600 - 56,341,884 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11056,331,925 - 56,346,316 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01040,589,654 - 40,601,159 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11043,770,969 - 43,782,457 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1043,770,989 - 43,782,457 (+)Ensemblpanpan1.1panPan2
ZNF485
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1283,501,486 - 3,513,852 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl283,501,911 - 3,513,993 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha283,735,081 - 3,761,742 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0283,680,786 - 3,707,254 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl283,681,211 - 3,692,554 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1283,478,029 - 3,504,248 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0283,520,085 - 3,546,408 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0283,655,037 - 3,681,271 (-)NCBIUU_Cfam_GSD_1.0
Znf485
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721383,312,600 - 83,324,058 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049366173,459,895 - 3,471,584 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ZNF485
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1939,255,166 - 39,267,005 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl939,257,669 - 39,270,747 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605647,195,289 - 47,207,118 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in ZNF485
21 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 10q11.21-21.2(chr10:42335305-60284876)x1 copy number loss Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052506]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052506]|See cases [RCV000052506] Chr10:42335305..60284876 [GRCh38]
Chr10:42830753..62044634 [GRCh37]
Chr10:42150759..61714640 [NCBI36]
Chr10:10q11.21-21.2		 pathogenic
NM_145312.3(ZNF485):c.1258C>T (p.Pro420Ser) single nucleotide variant Malignant melanoma [RCV000068938] Chr10:43617301 [GRCh38]
Chr10:44112749 [GRCh37]
Chr10:43432755 [NCBI36]
Chr10:10q11.21		 not provided
GRCh38/hg38 10q11.21-21.1(chr10:42884294-52265317)x3 copy number gain See cases [RCV000134381] Chr10:42884294..52265317 [GRCh38]
Chr10:43379742..54025077 [GRCh37]
Chr10:42699748..53695083 [NCBI36]
Chr10:10q11.21-21.1		 pathogenic
GRCh38/hg38 10q11.21-11.23(chr10:42395201-50877059)x3 copy number gain See cases [RCV000134846] Chr10:42395201..50877059 [GRCh38]
Chr10:42890649..52636819 [GRCh37]
Chr10:42210655..52306825 [NCBI36]
Chr10:10q11.21-11.23		 pathogenic
GRCh38/hg38 10q11.21-22.2(chr10:42685306-73715908)x3 copy number gain See cases [RCV000134848] Chr10:42685306..73715908 [GRCh38]
Chr10:43180754..75475666 [GRCh37]
Chr10:42500760..75145672 [NCBI36]
Chr10:10q11.21-22.2		 pathogenic
GRCh38/hg38 10p15.1-q11.22(chr10:4604734-48074662)x3 copy number gain See cases [RCV000141497] Chr10:4604734..48074662 [GRCh38]
Chr10:4646926..47531169 [GRCh37]
Chr10:4636926..47125152 [NCBI36]
Chr10:10p15.1-q11.22		 benign
GRCh38/hg38 10q11.21-21.3(chr10:42112187-67400675)x3 copy number gain See cases [RCV000142967] Chr10:42112187..67400675 [GRCh38]
Chr10:42607635..69160433 [GRCh37]
Chr10:41927641..68830439 [NCBI36]
Chr10:10q11.21-21.3		 pathogenic
NC_000010.10:g.43611191_61663279inv inversion Pediatric metastatic thyroid tumour [RCV000585841] Chr10:43611191..61663279 [GRCh37]
Chr10:10q11.21-21.2		 likely pathogenic
GRCh37/hg19 10p15.3-q26.3(chr10:93297-135378918)x3 copy number gain See cases [RCV000448750] Chr10:93297..135378918 [GRCh37]
Chr10:10p15.3-q26.3		 pathogenic
GRCh37/hg19 10q11.21(chr10:42706947-44489498)x3 copy number gain See cases [RCV000510280] Chr10:42706947..44489498 [GRCh37]
Chr10:10q11.21		 uncertain significance
GRCh37/hg19 10p15.3-q26.3(chr10:100027-135427143) copy number gain See cases [RCV000511389] Chr10:100027..135427143 [GRCh37]
Chr10:10p15.3-q26.3		 pathogenic|uncertain significance
GRCh37/hg19 10p15.3-q11.23(chr10:100026-50961640)x3 copy number gain See cases [RCV000510893] Chr10:100026..50961640 [GRCh37]
Chr10:10p15.3-q11.23		 pathogenic
GRCh37/hg19 10p15.3-q26.3(chr10:100027-135427143)x3 copy number gain See cases [RCV000510861] Chr10:100027..135427143 [GRCh37]
Chr10:10p15.3-q26.3		 pathogenic
GRCh37/hg19 10q11.21-26.3(chr10:42347406-135534747)x1 copy number loss Poly (ADP-Ribose) polymerase inhibitor response [RCV000626438] Chr10:42347406..135534747 [GRCh37]
Chr10:10q11.21-26.3		 drug response
NM_145312.4(ZNF485):c.67A>C (p.Ile23Leu) single nucleotide variant Inborn genetic diseases [RCV003277131] Chr10:43608656 [GRCh38]
Chr10:44104104 [GRCh37]
Chr10:10q11.21		 uncertain significance
GRCh37/hg19 10p15.3-q26.3(chr10:98087-135477883)x3 copy number gain not provided [RCV000749465] Chr10:98087..135477883 [GRCh37]
Chr10:10p15.3-q26.3		 pathogenic
GRCh37/hg19 10p15.3-q26.3(chr10:73232-135524321)x3 copy number gain not provided [RCV000749464] Chr10:73232..135524321 [GRCh37]
Chr10:10p15.3-q26.3		 pathogenic
GRCh37/hg19 10p11.21-q11.22(chr10:37149872-46169876)x3 copy number gain not provided [RCV000762700] Chr10:37149872..46169876 [GRCh37]
Chr10:10p11.21-q11.22		 likely pathogenic
GRCh37/hg19 10q11.21(chr10:43683704-44151599) copy number gain not specified [RCV002052869] Chr10:43683704..44151599 [GRCh37]
Chr10:10q11.21		 uncertain significance
GRCh37/hg19 10p15.3-q11.22(chr10:135655-47688677)x4 copy number gain Mosaic supernumerary isodicentric chromosome 10 [RCV001825164] Chr10:135655..47688677 [GRCh37]
Chr10:10p15.3-q11.22		 not provided
NM_145312.4(ZNF485):c.203A>G (p.Glu68Gly) single nucleotide variant Inborn genetic diseases [RCV003260916] Chr10:43609306 [GRCh38]
Chr10:44104754 [GRCh37]
Chr10:10q11.21		 uncertain significance
NM_145312.4(ZNF485):c.1058C>T (p.Pro353Leu) single nucleotide variant Inborn genetic diseases [RCV003287297] Chr10:43617101 [GRCh38]
Chr10:44112549 [GRCh37]
Chr10:10q11.21		 uncertain significance
NM_145312.4(ZNF485):c.337A>G (p.Met113Val) single nucleotide variant Inborn genetic diseases [RCV002968463] Chr10:43616380 [GRCh38]
Chr10:44111828 [GRCh37]
Chr10:10q11.21		 uncertain significance
NM_145312.4(ZNF485):c.224A>G (p.Glu75Gly) single nucleotide variant Inborn genetic diseases [RCV002683098] Chr10:43609327 [GRCh38]
Chr10:44104775 [GRCh37]
Chr10:10q11.21		 uncertain significance
NM_145312.4(ZNF485):c.641A>G (p.His214Arg) single nucleotide variant Inborn genetic diseases [RCV002906634] Chr10:43616684 [GRCh38]
Chr10:44112132 [GRCh37]
Chr10:10q11.21		 uncertain significance
NM_145312.4(ZNF485):c.490G>C (p.Gly164Arg) single nucleotide variant Inborn genetic diseases [RCV002793554] Chr10:43616533 [GRCh38]
Chr10:44111981 [GRCh37]
Chr10:10q11.21		 uncertain significance
NM_145312.4(ZNF485):c.341T>C (p.Met114Thr) single nucleotide variant Inborn genetic diseases [RCV002925268] Chr10:43616384 [GRCh38]
Chr10:44111832 [GRCh37]
Chr10:10q11.21		 uncertain significance
NM_145312.4(ZNF485):c.208T>C (p.Trp70Arg) single nucleotide variant Inborn genetic diseases [RCV003000567] Chr10:43609311 [GRCh38]
Chr10:44104759 [GRCh37]
Chr10:10q11.21		 uncertain significance
NM_145312.4(ZNF485):c.1058C>G (p.Pro353Arg) single nucleotide variant Inborn genetic diseases [RCV002924074] Chr10:43617101 [GRCh38]
Chr10:44112549 [GRCh37]
Chr10:10q11.21		 uncertain significance
NM_145312.4(ZNF485):c.152G>A (p.Gly51Glu) single nucleotide variant Inborn genetic diseases [RCV002703966] Chr10:43609255 [GRCh38]
Chr10:44104703 [GRCh37]
Chr10:10q11.21		 uncertain significance
NM_145312.4(ZNF485):c.220C>G (p.Arg74Gly) single nucleotide variant Inborn genetic diseases [RCV002757043] Chr10:43609323 [GRCh38]
Chr10:44104771 [GRCh37]
Chr10:10q11.21		 uncertain significance
NM_145312.4(ZNF485):c.1211A>G (p.His404Arg) single nucleotide variant Inborn genetic diseases [RCV002640948] Chr10:43617254 [GRCh38]
Chr10:44112702 [GRCh37]
Chr10:10q11.21		 uncertain significance
NM_145312.4(ZNF485):c.389A>G (p.Tyr130Cys) single nucleotide variant Inborn genetic diseases [RCV002644617] Chr10:43616432 [GRCh38]
Chr10:44111880 [GRCh37]
Chr10:10q11.21		 uncertain significance
NM_145312.4(ZNF485):c.332G>A (p.Ser111Asn) single nucleotide variant Inborn genetic diseases [RCV002724139] Chr10:43616375 [GRCh38]
Chr10:44111823 [GRCh37]
Chr10:10q11.21		 uncertain significance
NM_145312.4(ZNF485):c.1105C>T (p.Leu369Phe) single nucleotide variant Inborn genetic diseases [RCV003220276] Chr10:43617148 [GRCh38]
Chr10:44112596 [GRCh37]
Chr10:10q11.21		 uncertain significance
GRCh37/hg19 10p13-q26.3(chr10:12829206-135427143) copy number loss Distal 10q deletion syndrome [RCV003319583] Chr10:12829206..135427143 [GRCh37]
Chr10:10p13-q26.3		 pathogenic
NM_145312.4(ZNF485):c.847T>C (p.Ser283Pro) single nucleotide variant Inborn genetic diseases [RCV003286650] Chr10:43616890 [GRCh38]
Chr10:44112338 [GRCh37]
Chr10:10q11.21		 uncertain significance
GRCh37/hg19 10p14-q26.3(chr10:11138692-135427143) copy number gain Distal trisomy 10q [RCV003319593] Chr10:11138692..135427143 [GRCh37]
Chr10:10p14-q26.3		 pathogenic
NM_145312.4(ZNF485):c.534G>T (p.Lys178Asn) single nucleotide variant Inborn genetic diseases [RCV003376936] Chr10:43616577 [GRCh38]
Chr10:44112025 [GRCh37]
Chr10:10q11.21		 uncertain significance
NM_145312.4(ZNF485):c.1321A>G (p.Ser441Gly) single nucleotide variant Inborn genetic diseases [RCV003366502] Chr10:43617364 [GRCh38]
Chr10:44112812 [GRCh37]
Chr10:10q11.21		 uncertain significance
NM_145312.4(ZNF485):c.65G>A (p.Arg22Gln) single nucleotide variant Inborn genetic diseases [RCV003350867] Chr10:43608654 [GRCh38]
Chr10:44104102 [GRCh37]
Chr10:10q11.21		 likely benign
GRCh37/hg19 10q11.21-24.2(chr10:42709645-100834951)x3 copy number gain not provided [RCV003484798] Chr10:42709645..100834951 [GRCh37]
Chr10:10q11.21-24.2		 pathogenic
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:738
Count of miRNA genes:427
Interacting mature miRNAs:460
Transcripts:ENST00000361807, ENST00000374435, ENST00000374437, ENST00000430885, ENST00000480678
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
RH121814  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371044,112,308 - 44,112,604UniSTSGRCh37
Build 361043,432,314 - 43,432,610RGDNCBI36
Celera1040,115,944 - 40,116,240RGD
Cytogenetic Map10q11.21UniSTS
HuRef1040,639,313 - 40,639,609UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 36 7 3 99 3 14 10 26 4 114 32 1 1
Low 2397 2379 1705 609 1352 450 4315 2084 3598 398 1344 1557 174 1 1203 2767 5 2
Below cutoff 6 598 14 12 477 12 27 103 110 17 2 24 1 20 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001318140 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001318141 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001318142 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001318143 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_145312 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011539498 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054365100 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AK074679 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK299707 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK313328 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL645634 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC014161 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX648149 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471160 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068268 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CQ783574 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DB448752 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DN994938 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KT584838 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000361807   ⟹   ENSP00000354694
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1043,606,438 - 43,617,904 (+)Ensembl
RefSeq Acc Id: ENST00000374435   ⟹   ENSP00000363558
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1043,606,426 - 43,617,903 (+)Ensembl
RefSeq Acc Id: ENST00000430885   ⟹   ENSP00000393570
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1043,606,419 - 43,616,395 (+)Ensembl
RefSeq Acc Id: ENST00000480678
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1043,606,419 - 43,607,400 (+)Ensembl
RefSeq Acc Id: NM_001318140   ⟹   NP_001305069
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381043,606,438 - 43,617,904 (+)NCBI
CHM1_11044,141,490 - 44,152,987 (+)NCBI
T2T-CHM13v2.01044,487,360 - 44,498,826 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001318141   ⟹   NP_001305070
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381043,606,438 - 43,617,904 (+)NCBI
CHM1_11044,141,490 - 44,152,987 (+)NCBI
T2T-CHM13v2.01044,487,360 - 44,498,826 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001318142   ⟹   NP_001305071
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381043,606,438 - 43,617,904 (+)NCBI
CHM1_11044,141,490 - 44,152,987 (+)NCBI
T2T-CHM13v2.01044,487,360 - 44,498,826 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001318143   ⟹   NP_001305072
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381043,606,438 - 43,617,904 (+)NCBI
CHM1_11044,141,490 - 44,152,987 (+)NCBI
T2T-CHM13v2.01044,487,360 - 44,498,826 (+)NCBI
Sequence:
RefSeq Acc Id: NM_145312   ⟹   NP_660355
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381043,606,438 - 43,617,904 (+)NCBI
GRCh371044,101,855 - 44,113,352 (+)RGD
Build 361043,421,881 - 43,433,358 (+)NCBI Archive
Celera1040,105,491 - 40,116,988 (+)RGD
HuRef1040,628,860 - 40,640,357 (+)RGD
CHM1_11044,141,490 - 44,152,987 (+)NCBI
T2T-CHM13v2.01044,487,360 - 44,498,826 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011539498   ⟹   XP_011537800
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381043,608,689 - 43,617,904 (+)NCBI
Sequence:
RefSeq Acc Id: XM_054365100   ⟹   XP_054221075
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01044,489,611 - 44,498,826 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_660355   ⟸   NM_145312
- Peptide Label: isoform a
- UniProtKB: B4DSE6 (UniProtKB/Swiss-Prot),   Q96CL0 (UniProtKB/Swiss-Prot),   Q8NCK3 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_011537800   ⟸   XM_011539498
- Peptide Label: isoform X1
- UniProtKB: Q8NCK3 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001305069   ⟸   NM_001318140
- Peptide Label: isoform a
- UniProtKB: B4DSE6 (UniProtKB/Swiss-Prot),   Q96CL0 (UniProtKB/Swiss-Prot),   Q8NCK3 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001305071   ⟸   NM_001318142
- Peptide Label: isoform b
- UniProtKB: Q8NCK3 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001305072   ⟸   NM_001318143
- Peptide Label: isoform b
- UniProtKB: Q8NCK3 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001305070   ⟸   NM_001318141
- Peptide Label: isoform a
- UniProtKB: B4DSE6 (UniProtKB/Swiss-Prot),   Q96CL0 (UniProtKB/Swiss-Prot),   Q8NCK3 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSP00000363558   ⟸   ENST00000374435
RefSeq Acc Id: ENSP00000354694   ⟸   ENST00000361807
RefSeq Acc Id: ENSP00000393570   ⟸   ENST00000430885
RefSeq Acc Id: XP_054221075   ⟸   XM_054365100
- Peptide Label: isoform X1
Protein Domains
KRAB

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8NCK3-F1-model_v2 AlphaFold Q8NCK3 1-441 view protein structure

Promoters
RGD ID:6788402
Promoter ID:HG_KWN:9257
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   HeLa_S3,   K562,   Lymphoblastoid
Transcripts:OTTHUMT00000346855,   OTTHUMT00000346856,   UC001JAY.1,   UC001JAZ.1
Position:
Human AssemblyChrPosition (strand)Source
Build 361043,421,761 - 43,422,261 (+)MPROMDB
RGD ID:7217405
Promoter ID:EPDNEW_H14448
Type:initiation region
Name:ZNF485_1
Description:zinc finger protein 485
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381043,606,441 - 43,606,501EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:23440 AgrOrtholog
COSMIC ZNF485 COSMIC
Ensembl Genes ENSG00000198298 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000361807 ENTREZGENE
  ENST00000361807.8 UniProtKB/Swiss-Prot
  ENST00000374435 ENTREZGENE
  ENST00000374435.3 UniProtKB/Swiss-Prot
  ENST00000430885.5 UniProtKB/TrEMBL
Gene3D-CATH 6.10.140.140 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Classic Zinc Finger UniProtKB/Swiss-Prot
GTEx ENSG00000198298 GTEx
HGNC ID HGNC:23440 ENTREZGENE
Human Proteome Map ZNF485 Human Proteome Map
InterPro KRAB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  KRAB_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_C2H2_sf UniProtKB/Swiss-Prot
  Znf_C2H2_type UniProtKB/Swiss-Prot
KEGG Report hsa:220992 UniProtKB/Swiss-Prot
NCBI Gene 220992 ENTREZGENE
PANTHER IP01015P-RELATED UniProtKB/Swiss-Prot
  KRAB DOMAIN C2H2 ZINC FINGER UniProtKB/TrEMBL
  ZINC FINGER PROTEIN 485 UniProtKB/Swiss-Prot
  ZINC FINGER PROTEIN 8 UniProtKB/TrEMBL
Pfam KRAB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  zf-C2H2 UniProtKB/Swiss-Prot
PharmGKB PA134887005 PharmGKB
PROSITE KRAB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_1 UniProtKB/Swiss-Prot
  ZINC_FINGER_C2H2_2 UniProtKB/Swiss-Prot
SMART KRAB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZnF_C2H2 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF109640 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF57667 UniProtKB/Swiss-Prot
UniProt B4DSE6 ENTREZGENE
  C9JV60_HUMAN UniProtKB/TrEMBL
  Q8NCK3 ENTREZGENE
  Q96CL0 ENTREZGENE
  ZN485_HUMAN UniProtKB/Swiss-Prot
UniProt Secondary B4DSE6 UniProtKB/Swiss-Prot
  Q96CL0 UniProtKB/Swiss-Prot