Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Pcdhga3 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of PCDHGA3 mRNA | CTD | PMID:33956508 | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | EXP | | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of PCDHGA3 mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in decreased expression of PCDHGA3 mRNA | CTD | PMID:28628672 | 4,4'-sulfonyldiphenol | multiple interactions | EXP | | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in decreased expression of PCDHGA3 mRNA | CTD | PMID:28628672 | aflatoxin B1 | decreases methylation | EXP | | 6480464 | Aflatoxin B1 results in decreased methylation of PCDHGA3 gene | CTD | PMID:27153756 | amosite asbestos | decreases methylation | EXP | | 6480464 | Asbestos and Amosite results in decreased methylation of PCDHGA3 promoter | CTD | PMID:29626692 | arsenite(3-) | increases methylation | EXP | | 6480464 | arsenite results in increased methylation of PCDHGA3 promoter | CTD | PMID:23974009 | benzo[a]pyrene | increases methylation | ISO | Pcdhga3 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased methylation of PCDHGA3 exon and Benzo(a)pyrene results in increased methylation of PCDHGA3 intron | CTD | PMID:27901495 | bisphenol A | increases expression | ISO | Pcdhga3 (Rattus norvegicus) | 6480464 | bisphenol A results in increased expression of PCDHGA3 mRNA | CTD | PMID:30816183 more ... | bisphenol F | multiple interactions | EXP | | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of PCDHGA3 mRNA | CTD | PMID:28628672 | chlorpyrifos | decreases expression | ISO | Pcdhga3 (Mus musculus) | 6480464 | Chlorpyrifos results in decreased expression of PCDHGA3 mRNA | CTD | PMID:37019170 | crocidolite asbestos | decreases methylation | EXP | | 6480464 | Asbestos and Crocidolite results in decreased methylation of PCDHGA3 promoter | CTD | PMID:29626692 | dexamethasone | multiple interactions | EXP | | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of PCDHGA3 mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in decreased expression of PCDHGA3 mRNA | CTD | PMID:28628672 | doxorubicin | affects methylation | ISO | Pcdhga3 (Rattus norvegicus) | 6480464 | Doxorubicin affects the methylation of PCDHGA3 gene | CTD | PMID:28962528 | doxorubicin | decreases expression | EXP | | 6480464 | Doxorubicin results in decreased expression of PCDHGA3 mRNA | CTD | PMID:29803840 | ethanol | increases expression | ISO | Pcdhga3 (Mus musculus) | 6480464 | Ethanol results in increased expression of PCDHGA3 mRNA | CTD | PMID:30319688 | furan | increases methylation | ISO | Pcdhga3 (Rattus norvegicus) | 6480464 | furan results in increased methylation of PCDHGA3 gene | CTD | PMID:22079235 | indometacin | multiple interactions | EXP | | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of PCDHGA3 mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in decreased expression of PCDHGA3 mRNA | CTD | PMID:28628672 | lipopolysaccharide | decreases expression | EXP | | 6480464 | Lipopolysaccharides results in decreased expression of PCDHGA3 mRNA | CTD | PMID:35811015 | lipopolysaccharide | multiple interactions | EXP | | 6480464 | S-(1 and 2-dichlorovinyl)cysteine inhibits the reaction [Lipopolysaccharides results in decreased expression of PCDHGA3 mRNA] | CTD | PMID:35811015 | methotrexate | decreases expression | EXP | | 6480464 | Methotrexate results in decreased expression of PCDHGA3 mRNA | CTD | PMID:24449571 | progesterone | decreases expression | EXP | | 6480464 | Progesterone results in decreased expression of PCDHGA3 mRNA | CTD | PMID:18070364 | raloxifene | increases expression | EXP | | 6480464 | Raloxifene Hydrochloride results in increased expression of PCDHGA3 mRNA | CTD | PMID:19429434 | S-(1,2-dichlorovinyl)-L-cysteine | multiple interactions | EXP | | 6480464 | S-(1 and 2-dichlorovinyl)cysteine inhibits the reaction [Lipopolysaccharides results in decreased expression of PCDHGA3 mRNA] | CTD | PMID:35811015 | valproic acid | increases methylation | EXP | | 6480464 | Valproic Acid results in increased methylation of PCDHGA3 gene | CTD | PMID:29154799 | |