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Gene: SESTD1 (SEC14 and spectrin domain containing 1) Homo sapiens
Symbol: SESTD1
Name: SEC14 and spectrin domain containing 1
Description: Exhibits phospholipid binding activity. Involved in negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel. Localizes to the intermediate filament cytoskeleton. Colocalizes with the calcium channel complex; INTERACTS WITH (-)-demecolcine; (-)-epigallocatechin 3-gallate; aflatoxin B1.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: DKFZp434O0515; huntingtin-interacting protein-like protein; SEC14 and spectrin domains 1; SEC14 domain and spectrin repeat-containing protein 1; SOLO
Mus musculus (house mouse) : Sestd1 (SEC14 and spectrin domains 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Sestd1 (SEC14 and spectrin domain containing 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sestd1 (SEC14 and spectrin domain containing 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SESTD1 (SEC14 and spectrin domain containing 1)
Canis lupus familiaris (dog) : SESTD1 (SEC14 and spectrin domain containing 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sestd1 (SEC14 and spectrin domain containing 1)
Sus scrofa (pig) : SESTD1 (SEC14 and spectrin domain containing 1)
Chlorocebus sabaeus (green monkey) : SESTD1 (SEC14 and spectrin domain containing 1)
Heterocephalus glaber (naked mole-rat) : Sestd1 (SEC14 and spectrin domain containing 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl2179,101,678 - 179,264,832 (-)Ensembl
GRCh382179,101,678 - 179,264,832 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372179,966,419 - 180,129,350 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362179,681,776 - 179,764,838 (-)NCBINCBI36hg18NCBI36
Build 342179,799,036 - 179,954,752NCBI
Celera2173,560,816 - 173,723,730 (-)NCBI
Cytogenetic Map2q31.2NCBI
HuRef2171,835,120 - 171,981,416 (-)NCBIHuRef
CHM1_12179,972,587 - 180,135,211 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on SESTD1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1349123
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.