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Gene: GAGE8 (G antigen 8) Homo sapiens
Symbol: GAGE8
Name: G antigen 8
Description: This gene belongs to a family of genes that are expressed in a variety of tumors but not in normal tissues, except for the testis. The sequences of the family members are highly related but differ by scattered nucleotide substitutions. The antigenic peptide YRPRPRRY, which is also encoded by several other family members, is recognized by autologous cytolytic T lymphocytes. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: cancer/testis antigen 4.8; cancer/testis antigen family 4, member 8; CT4.8; G antigen 2D; GAGE-2D; GAGE-8; GAGE2D; MGC190052; MGC190826; MGC26395
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
NCBI Annotation Information: Genome Annotation Status: not in current annotation release
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh37X49,207,160 - 49,214,420 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X49,084,551 - 49,091,867 (+)NCBINCBI36hg18NCBI36
Build 34X49,057,353 - 49,064,668NCBI
CeleraX53,437,864 - 53,440,313 (+)NCBI
Cytogenetic MapXp11NCBI
HuRefX46,815,733 - 46,831,861 (+)NCBIHuRef

Disease Annotations
Gene Ontology Annotations
References - curated
References - uncurated




Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on GAGE8
Alliance Gene
Ensembl Gene
JBrowse: hg19
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1349095
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.