TAAR6 (trace amine associated receptor 6)

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Gene: TAAR6 (trace amine associated receptor 6) Homo sapiens

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Symbol:

TAAR6

Name:

trace amine associated receptor 6

RGD ID:

1348964

HGNC Page

HGNC:20978

Description:

Predicted to enable trace-amine receptor activity. Predicted to be involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway. Is active in plasma membrane.

Type:

protein-coding

RefSeq Status:

REVIEWED

Previously known as:

RP11-295F4.3; schizophrenia disorder 5; SCZD5; TA4; taR-4; taR-6; TAR4; TAR6; trace amine receptor 4; trace amine receptor 6; trace amine-associated receptor 6; TRAR4

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Related Pseudogenes:

TAAR7P

Allele / Splice:

See ClinVar data

Latest Assembly:

GRCh38 - Human Genome Assembly GRCh38

Position:

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	6	132,570,322 - 132,571,359 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	6	132,570,322 - 132,571,359 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	6	132,891,461 - 132,892,498 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	6	132,933,154 - 132,934,191 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	6	132,933,153 - 132,934,191	NCBI
Celera	6	133,638,298 - 133,639,335 (+)	NCBI		Celera
Cytogenetic Map	6	q23.2	NCBI
HuRef	6	130,466,379 - 130,467,416 (+)	NCBI		HuRef
CHM1_1	6	133,155,132 - 133,156,169 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	6	133,765,283 - 133,766,320 (+)	NCBI		T2T-CHM13v2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

4,4'-sulfonyldiphenol (ISO)

ammonium chloride (ISO)

benzo[a]pyrene (EXP)

bisphenol A (ISO)

CGP 52608 (EXP)

leflunomide (EXP)

trichloroethene (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

adenylate cyclase-activating G protein-coupled receptor signaling pathway (ISS)

G protein-coupled receptor signaling pathway (IEA,TAS)

Cellular Component

membrane (IEA)

plasma membrane (IDA,IEA)

Molecular Function

G protein-coupled receptor activity (IEA,TAS)

trace-amine receptor activity (IBA,IEA,ISS)

References

References - curated

#	Reference Title	Reference Citation
1.	Trace amines: identification of a family of mammalian G protein-coupled receptors.	Borowsky B, etal., Proc Natl Acad Sci U S A 2001 Jul 31;98(16):8966-71.
2.	GOAs Human GO annotations	GOA_HUMAN data from the GO Consortium
3.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
4.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:9226366	PMID:9674972	PMID:12477932	PMID:14574404	PMID:15329799	PMID:15489334	PMID:15718104	PMID:16075187	PMID:16189505	PMID:16878137	PMID:17097106	PMID:17505468
PMID:17895926	PMID:17957234	PMID:18198266	PMID:18240029	PMID:18583103	PMID:18628684	PMID:18973992	PMID:18978678	PMID:19345712	PMID:19582769	PMID:19643584	PMID:19766166
PMID:20493543	PMID:21873635	PMID:25919112	PMID:35008636	PMID:36139098	PMID:37225986

Genomics

Comparative Map Data

TAAR6
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	6	132,570,322 - 132,571,359 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	6	132,570,322 - 132,571,359 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	6	132,891,461 - 132,892,498 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	6	132,933,154 - 132,934,191 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	6	132,933,153 - 132,934,191	NCBI
Celera	6	133,638,298 - 133,639,335 (+)	NCBI		Celera
Cytogenetic Map	6	q23.2	NCBI
HuRef	6	130,466,379 - 130,467,416 (+)	NCBI		HuRef
CHM1_1	6	133,155,132 - 133,156,169 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	6	133,765,283 - 133,766,320 (+)	NCBI		T2T-CHM13v2.0

Taar6
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	10	23,860,507 - 23,861,544 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	10	23,860,507 - 23,861,544 (-)	Ensembl		GRCm39 Ensembl
GRCm38	10	23,984,609 - 23,985,646 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	10	23,984,609 - 23,985,646 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	10	23,704,415 - 23,705,452 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	10	23,674,025 - 23,675,062 (-)	NCBI		MGSCv36	mm8
Celera	10	24,918,005 - 24,919,042 (-)	NCBI		Celera
Cytogenetic Map	10	A4	NCBI
cM Map	10	11.4	NCBI

Taar6
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	23,277,717 - 23,278,754 (+)	NCBI		GRCr8
mRatBN7.2	1	21,458,475 - 21,459,512 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	21,458,111 - 21,460,652 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	21,235,555 - 21,236,592 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	27,235,596 - 27,236,633 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	21,435,339 - 21,436,376 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	22,536,199 - 22,537,236 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	22,536,199 - 22,537,236 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	24,011,141 - 24,012,178 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	21,984,658 - 21,985,695 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	21,987,602 - 21,988,640 (+)	NCBI
Celera	1	20,202,914 - 20,203,951 (+)	NCBI		Celera
Cytogenetic Map	1	p12	NCBI

TAAR6
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	5	152,552,749 - 152,554,953 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	6	150,459,858 - 150,462,058 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	6	130,346,489 - 130,348,689 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	6	134,454,665 - 134,455,730 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	6	134,454,665 - 134,455,615 (+)	Ensembl	panpan1.1		panPan2

LOC100154422
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1	1	31,124,661 - 31,125,693 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	34,661,232 - 34,671,105 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

TAAR6
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	13	40,972,175 - 40,975,089 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	13	40,972,618 - 40,973,691 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666040	13,160,358 - 13,161,395 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Variants

Variants in TAAR6
12 total Variants

Clinical Variants

Name	Type	Condition(s)	Position(s)	Clinical significance
GRCh38/hg38 6q23.2(chr6:132455272-133141153)x3	copy number gain	See cases [RCV000053388]	Chr6:132455272..133141153 [GRCh38] Chr6:132776411..133462292 [GRCh37] Chr6:132818104..133503985 [NCBI36] Chr6:6q23.2	uncertain significance
NM_175067.1(TAAR6):c.306G>A (p.Arg102=)	single nucleotide variant	Malignant melanoma [RCV000061316]	Chr6:132570627 [GRCh38] Chr6:132891766 [GRCh37] Chr6:132933459 [NCBI36] Chr6:6q23.2	not provided
GRCh38/hg38 6q13-24.1(chr6:74382807-142040500)x3	copy number gain	See cases [RCV000139729]	Chr6:74382807..142040500 [GRCh38] Chr6:75092523..142361637 [GRCh37] Chr6:75149243..142403330 [NCBI36] Chr6:6q13-24.1	pathogenic
GRCh37/hg19 6q23.2(chr6:132859724-132910636)x1	copy number loss	See cases [RCV000446076]	Chr6:132859724..132910636 [GRCh37] Chr6:6q23.2	uncertain significance
GRCh37/hg19 6p25.3-q27(chr6:156975-170919482)x3	copy number gain	See cases [RCV000512067]	Chr6:156975..170919482 [GRCh37] Chr6:6p25.3-q27	pathogenic
GRCh37/hg19 6p25.3-q27(chr6:156975-170919482)	copy number gain	See cases [RCV000510595]	Chr6:156975..170919482 [GRCh37] Chr6:6p25.3-q27	pathogenic
NM_175067.1(TAAR6):c.827T>C (p.Ile276Thr)	single nucleotide variant	not specified [RCV004324714]	Chr6:132571148 [GRCh38] Chr6:132892287 [GRCh37] Chr6:6q23.2	uncertain significance
GRCh37/hg19 6q23.2-23.3(chr6:131388023-137469640)x1	copy number loss	not provided [RCV000682724]	Chr6:131388023..137469640 [GRCh37] Chr6:6q23.2-23.3	pathogenic
GRCh37/hg19 6q23.2-23.3(chr6:132002460-137160850)x1	copy number loss	not provided [RCV000682725]	Chr6:132002460..137160850 [GRCh37] Chr6:6q23.2-23.3	pathogenic
GRCh37/hg19 6p25.3-q27(chr6:60107-171054786)x3	copy number gain	not provided [RCV000745400]	Chr6:60107..171054786 [GRCh37] Chr6:6p25.3-q27	pathogenic
GRCh37/hg19 6p25.3-q27(chr6:108666-170980171)x3	copy number gain	not provided [RCV000745403]	Chr6:108666..170980171 [GRCh37] Chr6:6p25.3-q27	pathogenic
GRCh37/hg19 6p25.3-q27(chr6:165632-170919470)x3	copy number gain	not provided [RCV000745404]	Chr6:165632..170919470 [GRCh37] Chr6:6p25.3-q27	pathogenic
NM_175067.1(TAAR6):c.162G>A (p.Met54Ile)	single nucleotide variant	not provided [RCV000953545]	Chr6:132570483 [GRCh38] Chr6:132891622 [GRCh37] Chr6:6q23.2	benign
NM_175067.1(TAAR6):c.296A>G (p.Tyr99Cys)	single nucleotide variant	not provided [RCV000954669]	Chr6:132570617 [GRCh38] Chr6:132891756 [GRCh37] Chr6:6q23.2	benign
Single allele	deletion	Interstitial 6q microdeletion syndrome [RCV002280353]	Chr6:115941808..133892653 [GRCh38] Chr6:6q22.1-23.2	pathogenic
GRCh37/hg19 6q23.1-23.3(chr6:130769034-136009217)x1	copy number loss	not provided [RCV001829086]	Chr6:130769034..136009217 [GRCh37] Chr6:6q23.1-23.3	pathogenic
GRCh37/hg19 6q23.2(chr6:132875123-133509642)x3	copy number gain	not provided [RCV001834192]	Chr6:132875123..133509642 [GRCh37] Chr6:6q23.2	uncertain significance
NM_175067.1(TAAR6):c.637A>G (p.Met213Val)	single nucleotide variant	not specified [RCV004310905]	Chr6:132570958 [GRCh38] Chr6:132892097 [GRCh37] Chr6:6q23.2	uncertain significance
NM_175067.1(TAAR6):c.796G>A (p.Ala266Thr)	single nucleotide variant	not specified [RCV004092556]	Chr6:132571117 [GRCh38] Chr6:132892256 [GRCh37] Chr6:6q23.2	uncertain significance
NM_175067.1(TAAR6):c.485T>G (p.Met162Arg)	single nucleotide variant	not specified [RCV004205895]	Chr6:132570806 [GRCh38] Chr6:132891945 [GRCh37] Chr6:6q23.2	uncertain significance
NM_175067.1(TAAR6):c.77C>T (p.Pro26Leu)	single nucleotide variant	not specified [RCV004205896]	Chr6:132570398 [GRCh38] Chr6:132891537 [GRCh37] Chr6:6q23.2	uncertain significance
NM_175067.1(TAAR6):c.203A>G (p.Asn68Ser)	single nucleotide variant	not specified [RCV004194444]	Chr6:132570524 [GRCh38] Chr6:132891663 [GRCh37] Chr6:6q23.2	uncertain significance
NM_175067.1(TAAR6):c.41G>A (p.Cys14Tyr)	single nucleotide variant	not specified [RCV004251727]	Chr6:132570362 [GRCh38] Chr6:132891501 [GRCh37] Chr6:6q23.2	uncertain significance
NM_175067.1(TAAR6):c.1022T>C (p.Phe341Ser)	single nucleotide variant	not specified [RCV004266450]	Chr6:132571343 [GRCh38] Chr6:132892482 [GRCh37] Chr6:6q23.2	uncertain significance
NM_175067.1(TAAR6):c.88G>C (p.Gly30Arg)	single nucleotide variant	not specified [RCV004276285]	Chr6:132570409 [GRCh38] Chr6:132891548 [GRCh37] Chr6:6q23.2	uncertain significance
GRCh37/hg19 6q22.31-23.3(chr6:120218852-137160850)x1	copy number loss	not provided [RCV003482930]	Chr6:120218852..137160850 [GRCh37] Chr6:6q22.31-23.3	pathogenic
GRCh37/hg19 6q22.31-25.3(chr6:119840686-156623091)x3	copy number gain	not specified [RCV003986631]	Chr6:119840686..156623091 [GRCh37] Chr6:6q22.31-25.3	pathogenic
GRCh37/hg19 6q23.2-24.2(chr6:131569837-145572239)x3	copy number gain	not specified [RCV003986663]	Chr6:131569837..145572239 [GRCh37] Chr6:6q23.2-24.2	pathogenic
NM_175067.1(TAAR6):c.408C>A (p.Asp136Glu)	single nucleotide variant	not specified [RCV004466086]	Chr6:132570729 [GRCh38] Chr6:132891868 [GRCh37] Chr6:6q23.2	uncertain significance
NM_175067.1(TAAR6):c.614C>T (p.Ser205Phe)	single nucleotide variant	not specified [RCV004466088]	Chr6:132570935 [GRCh38] Chr6:132892074 [GRCh37] Chr6:6q23.2	uncertain significance
NM_175067.1(TAAR6):c.769G>A (p.Ala257Thr)	single nucleotide variant	not specified [RCV004466090]	Chr6:132571090 [GRCh38] Chr6:132892229 [GRCh37] Chr6:6q23.2	uncertain significance
NM_175067.1(TAAR6):c.8G>T (p.Ser3Ile)	single nucleotide variant	not specified [RCV004466091]	Chr6:132570329 [GRCh38] Chr6:132891468 [GRCh37] Chr6:6q23.2	uncertain significance
NM_175067.1(TAAR6):c.704G>A (p.Gly235Asp)	single nucleotide variant	not specified [RCV004466089]	Chr6:132571025 [GRCh38] Chr6:132892164 [GRCh37] Chr6:6q23.2	uncertain significance
NM_175067.1(TAAR6):c.183G>C (p.Lys61Asn)	single nucleotide variant	not specified [RCV004466085]	Chr6:132570504 [GRCh38] Chr6:132891643 [GRCh37] Chr6:6q23.2	uncertain significance
NM_175067.1(TAAR6):c.577G>A (p.Val193Ile)	single nucleotide variant	not specified [RCV004466087]	Chr6:132570898 [GRCh38] Chr6:132892037 [GRCh37] Chr6:6q23.2	likely benign
NM_175067.1(TAAR6):c.628A>G (p.Thr210Ala)	single nucleotide variant	not specified [RCV004681889]	Chr6:132570949 [GRCh38] Chr6:132892088 [GRCh37] Chr6:6q23.2	uncertain significance
NM_175067.1(TAAR6):c.150C>A (p.Asn50Lys)	single nucleotide variant	not specified [RCV004671027]	Chr6:132570471 [GRCh38] Chr6:132891610 [GRCh37] Chr6:6q23.2	uncertain significance
NC_000006.11:g.(?_131894423)_(133849943_?)del	deletion	not provided [RCV004578838]	Chr6:131894423..133849943 [GRCh37] Chr6:6q23.2	pathogenic

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	44
Count of miRNA genes:	35
Interacting mature miRNAs:	35
Transcripts:	ENST00000275198
Prediction methods:	Microtar, Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region

D6S1009

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	6	137,302,192 - 137,302,430	UniSTS	GRCh37
Build 36	6	137,343,885 - 137,344,123	RGD	NCBI36
Celera	6	138,042,656 - 138,042,894	RGD
Cytogenetic Map	6	q23.2	UniSTS
Cytogenetic Map	6	q23-q25	UniSTS
HuRef	6	134,866,335 - 134,866,573	UniSTS
Marshfield Genetic Map	6	137.74	UniSTS
Marshfield Genetic Map	6	137.74	RGD
deCODE Assembly Map	6	138.76	UniSTS
Stanford-G3 RH Map	6	5696.0	UniSTS
Stanford-G3 RH Map	6	5703.0	UniSTS
Whitehead-RH Map	6	772.1	UniSTS
Whitehead-YAC Contig Map	6		UniSTS
NCBI RH Map	6	1538.9	UniSTS

D6S1056

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	6	94,097,508 - 94,097,753	UniSTS	GRCh37
Build 36	6	94,154,229 - 94,154,474	RGD	NCBI36
Celera	6	94,518,242 - 94,518,495	RGD
Cytogenetic Map	6	q16.1	UniSTS
Cytogenetic Map	6	q23.2	UniSTS
HuRef	6	91,317,646 - 91,317,899	UniSTS
Marshfield Genetic Map	6	102.81	RGD
Marshfield Genetic Map	6	102.81	UniSTS
deCODE Assembly Map	6	100.5	UniSTS
Stanford-G3 RH Map	6	4120.0	UniSTS
Whitehead-RH Map	6	622.2	UniSTS
Whitehead-YAC Contig Map	6		UniSTS
NCBI RH Map	6	1331.6	UniSTS

TA4-seq2-SNP1

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	6	132,890,907 - 132,891,479	UniSTS	GRCh37
Build 36	6	132,932,600 - 132,933,172	RGD	NCBI36
Celera	6	133,637,744 - 133,638,316	RGD
Cytogenetic Map	6	q23.2	UniSTS
HuRef	6	130,465,825 - 130,466,397	UniSTS

TA4-seq3-SNP2

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	6	132,891,421 - 132,891,990	UniSTS	GRCh37
Build 36	6	132,933,114 - 132,933,683	RGD	NCBI36
Celera	6	133,638,258 - 133,638,827	RGD
Cytogenetic Map	6	q23.2	UniSTS
HuRef	6	130,466,339 - 130,466,908	UniSTS

TA4-seq4-SNP1

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	6	132,891,907 - 132,892,484	UniSTS	GRCh37
Build 36	6	132,933,600 - 132,934,177	RGD	NCBI36
Celera	6	133,638,744 - 133,639,321	RGD
Cytogenetic Map	6	q23.2	UniSTS
HuRef	6	130,466,825 - 130,467,402	UniSTS

TA4-seq5-SNP3

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	6	132,892,401 - 132,892,917	UniSTS	GRCh37
Build 36	6	132,934,094 - 132,934,610	RGD	NCBI36
Celera	6	133,639,238 - 133,639,757	RGD
Cytogenetic Map	6	q23.2	UniSTS
HuRef	6	130,467,319 - 130,467,838	UniSTS

TRAR4__5131

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	6	132,892,057 - 132,892,632	UniSTS	GRCh37
Build 36	6	132,933,750 - 132,934,325	RGD	NCBI36
Celera	6	133,638,894 - 133,639,469	RGD
HuRef	6	130,466,975 - 130,467,550	UniSTS

Taar6

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	6	132,891,635 - 132,892,305	UniSTS	GRCh37
Celera	6	133,638,472 - 133,639,142	UniSTS
HuRef	6	130,466,553 - 130,467,223	UniSTS

UniSTS:481477

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	6	132,891,461 - 132,892,498	UniSTS	GRCh37
Celera	6	133,638,298 - 133,639,335	UniSTS
HuRef	6	130,466,379 - 130,467,416	UniSTS

Sequence

Nucleotide Sequences


RefSeq Transcripts	NG_016544	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_175067	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AF380192	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AL513524	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY183470	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC069157	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH471051	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CP068272	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENST00000275198 ⟹ ENSP00000275198

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	6	132,570,322 - 132,571,359 (+)	Ensembl

RefSeq Acc Id:

NM_175067 ⟹ NP_778237

RefSeq Status:

REVIEWED

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	6	132,570,322 - 132,571,359 (+)	NCBI
GRCh37	6	132,891,461 - 132,892,498 (+)	ENTREZGENE
Build 36	6	132,933,154 - 132,934,191 (+)	NCBI Archive
HuRef	6	130,466,379 - 130,467,416 (+)	ENTREZGENE
CHM1_1	6	133,155,132 - 133,156,169 (+)	NCBI
T2T-CHM13v2.0	6	133,765,283 - 133,766,320 (+)	NCBI

Sequence:

show sequence

ATGAGCAGCAATTCATCCCTGCTGGTGGCTGTGCAGCTGTGCTACGCGAACGTGAATGGGTCCT
GTGTGAAAATCCCCTTCTCGCCGGGATCCCGGGTGATTCTGTACATAGTGTTTGGCTTTGGGGC
TGTGCTGGCTGTGTTTGGAAACCTCCTGGTGATGATTTCAATCCTCCATTTCAAGCAGCTGCAC
TCTCCGACCAATTTTCTCGTTGCCTCTCTGGCCTGCGCTGATTTCTTGGTGGGTGTGACTGTGA
TGCCCTTCAGCATGGTCAGGACGGTGGAGAGCTGCTGGTATTTTGGGAGGAGTTTTTGTACTTT
CCACACCTGCTGTGATGTGGCATTTTGTTACTCTTCTCTCTTTCACTTGTGCTTCATCTCCATC
GACAGGTACATTGCGGTTACTGACCCCCTGGTCTATCCTACCAAGTTCACCGTATCTGTGTCAG
GAATTTGCATCAGCGTGTCCTGGATCCTGCCCCTCATGTACAGCGGTGCTGTGTTCTACACAGG
TGTCTATGACGATGGGCTGGAGGAATTATCTGATGCCCTAAACTGTATAGGAGGTTGTCAGACC
GTTGTAAATCAAAACTGGGTGTTGACAGATTTTCTATCCTTCTTTATACCTACCTTTATTATGA
TAATTCTGTATGGTAACATATTTCTTGTGGCTAGACGACAGGCGAAAAAGATAGAAAATACTGG
TAGCAAGACAGAATCATCCTCAGAGAGTTACAAAGCCAGAGTGGCCAGGAGAGAGAGAAAAGCA
GCTAAAACCCTGGGGGTCACAGTGGTAGCATTTATGATTTCATGGTTACCATATAGCATTGATT
CATTAATTGATGCCTTTATGGGCTTTATAACCCCTGCCTGTATTTATGAGATTTGCTGTTGGTG
TGCTTATTATAACTCAGCCATGAATCCTTTGATTTATGCTTTATTTTACCCATGGTTTAGGAAA
GCAATAAAAGTTATTGTAACTGGTCAGGTTTTAAAGAACAGTTCAGCAACCATGAATTTGTTTT
CTGAACATATATAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_778237	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH69157	(Get FASTA)	NCBI Sequence Viewer
	AAK71243	(Get FASTA)	NCBI Sequence Viewer
	AAO24661	(Get FASTA)	NCBI Sequence Viewer
	EAW48026	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSP00000275198
	ENSP00000275198.1
GenBank Protein	Q96RI8	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_778237 ⟸ NM_175067

- UniProtKB:

Q5VUQ4 (UniProtKB/Swiss-Prot), Q96RI8 (UniProtKB/Swiss-Prot)

- Sequence:

show sequence

MSSNSSLLVAVQLCYANVNGSCVKIPFSPGSRVILYIVFGFGAVLAVFGNLLVMISILHFKQLH
SPTNFLVASLACADFLVGVTVMPFSMVRTVESCWYFGRSFCTFHTCCDVAFCYSSLFHLCFISI
DRYIAVTDPLVYPTKFTVSVSGICISVSWILPLMYSGAVFYTGVYDDGLEELSDALNCIGGCQT
VVNQNWVLTDFLSFFIPTFIMIILYGNIFLVARRQAKKIENTGSKTESSSESYKARVARRERKA
AKTLGVTVVAFMISWLPYSIDSLIDAFMGFITPACIYEICCWCAYYNSAMNPLIYALFYPWFRK
AIKVIVTGQVLKNSSATMNLFSEHI

hide sequence

Ensembl Acc Id:

ENSP00000275198 ⟸ ENST00000275198

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q96RI8-F1-model_v2	AlphaFold	Q96RI8	1-345	view protein structure

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	HGNC:20978	AgrOrtholog
COSMIC	TAAR6	COSMIC
Ensembl Genes	ENSG00000146383	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENST00000275198	ENTREZGENE
	ENST00000275198.1	UniProtKB/Swiss-Prot
Gene3D-CATH	Rhodopsin 7-helix transmembrane proteins	UniProtKB/Swiss-Prot
GTEx	ENSG00000146383	GTEx
HGNC ID	HGNC:20978	ENTREZGENE
Human Proteome Map	TAAR6	Human Proteome Map
InterPro	GPCR_Rhodpsn	UniProtKB/Swiss-Prot
	GPCR_Rhodpsn_7TM	UniProtKB/Swiss-Prot
	TAAR	UniProtKB/Swiss-Prot
	TAAR_fam	UniProtKB/Swiss-Prot
KEGG Report	hsa:319100	UniProtKB/Swiss-Prot
NCBI Gene	319100	ENTREZGENE
OMIM	608923	OMIM
PANTHER	HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR	UniProtKB/Swiss-Prot
	TRACE AMINE-ASSOCIATED RECEPTOR 6	UniProtKB/Swiss-Prot
Pfam	7tm_1	UniProtKB/Swiss-Prot
PharmGKB	PA134881141	PharmGKB
PRINTS	GPCRRHODOPSN	UniProtKB/Swiss-Prot
	TRACEAMINER	UniProtKB/Swiss-Prot
PROSITE	G_PROTEIN_RECEP_F1_1	UniProtKB/Swiss-Prot
	G_PROTEIN_RECEP_F1_2	UniProtKB/Swiss-Prot
SMART	7TM_GPCR_Srsx	UniProtKB/Swiss-Prot
Superfamily-SCOP	Family A G protein-coupled receptor-like	UniProtKB/Swiss-Prot
UniProt	Q5VUQ4	ENTREZGENE
	Q96RI8	ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary	Q5VUQ4	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-04-05	TAAR6	trace amine associated receptor 6	SCZD5	schizophrenia disorder 5	Data merged from RGD:1345019	737654	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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