Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: PDZD3 (PDZ domain containing 3) Homo sapiens
Analyze
Symbol: PDZD3
Name: PDZ domain containing 3
Description: Exhibits guanylate cyclase inhibitor activity; protein C-terminus binding activity; and ubiquitin-specific protease binding activity. Involved in negative regulation of cGMP-mediated signaling. Localizes to apical junction complex; apical part of cell; and brush border.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: FLJ22756; IKEPP; intestinal and kidney enriched PDZ protein; intestinal and kidney-enriched PDZ protein; Na(+)/H(+) exchange regulatory cofactor NHE-RF4; na/Pi cotransporter C-terminal-associated protein 2; naPi-Cap2; natrium-phosphate cotransporter IIa C-terminal-associated protein 2; NHERF-4; NHERF4; PDZ domain containing 2; PDZ domain-containing protein 2; PDZ domain-containing protein 3; PDZK2; sodium-hydrogen exchanger regulatory factor 4
Orthologs:
Mus musculus (house mouse) : Pdzd3 (PDZ domain containing 3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Pdzd3 (PDZ domain containing 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pdzd3 (PDZ domain containing 3)
Pan paniscus (bonobo/pygmy chimpanzee) : PDZD3 (PDZ domain containing 3)
Canis lupus familiaris (dog) : PDZD3 (PDZ domain containing 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pdzd3 (PDZ domain containing 3)
Sus scrofa (pig) : PDZD3 (PDZ domain containing 3)
Chlorocebus sabaeus (African green monkey) : PDZD3 (PDZ domain containing 3)
Heterocephalus glaber (naked mole-rat) : Pdzd3 (PDZ domain containing 3)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl11119,185,457 - 119,190,223 (+)EnsemblGRCh38hg38GRCh38
GRCh3811119,185,457 - 119,190,218 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3711119,056,127 - 119,060,932 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3611118,561,405 - 118,566,130 (+)NCBINCBI36hg18NCBI36
Build 3411118,561,404 - 118,566,128NCBI
Celera11116,215,961 - 116,220,727 (+)NCBI
Cytogenetic Map11q23.3NCBI
HuRef11114,995,630 - 115,000,396 (+)NCBIHuRef
CHM1_111118,942,433 - 118,947,199 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on PDZD3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1348843
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-06-18
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.