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Gene: ESAM (endothelial cell adhesion molecule) Homo sapiens
Symbol: ESAM
Name: endothelial cell adhesion molecule
Description: Exhibits cell-cell adhesion mediator activity. Involved in several processes, including bicellular tight junction assembly; cell-cell adhesion; and regulation of actin cytoskeleton organization. Localizes to cell-cell junction; plasma membrane; and protein-containing complex; INTERACTS WITH 5-aza-2'-deoxycytidine; aflatoxin B1; antirheumatic drug.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2310008D05Rik; endothelial cell-selective adhesion molecule; HUEL (C4orf1)-interacting protein; LP4791 protein; W117m
Mus musculus (house mouse) : Esam (endothelial cell-specific adhesion molecule)  MGI  Alliance
Rattus norvegicus (Norway rat) : Esam (endothelial cell adhesion molecule)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : ESAM (endothelial cell adhesion molecule)
Canis lupus familiaris (dog) : ESAM (endothelial cell adhesion molecule)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Esam (endothelial cell adhesion molecule)
Sus scrofa (pig) : ESAM (endothelial cell adhesion molecule)
Chlorocebus sabaeus (African green monkey) : ESAM (endothelial cell adhesion molecule)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl11124,752,583 - 124,762,290 (-)EnsemblGRCh38hg38GRCh38
GRCh3811124,753,126 - 124,762,290 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3711124,623,019 - 124,632,223 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3611124,128,229 - 124,137,433 (-)NCBINCBI36hg18NCBI36
Build 3411124,128,241 - 124,137,385NCBI
Celera11121,783,196 - 121,792,400 (-)NCBI
Cytogenetic Map11q24.2NCBI
HuRef11120,565,472 - 120,574,614 (-)NCBIHuRef
CHM1_111124,509,116 - 124,518,320 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Candidate Gene Status
Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on ESAM
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1348841
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-06-23
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.