CD1B (CD1b molecule) - Rat Genome Database

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Gene: CD1B (CD1b molecule) Homo sapiens
Analyze
Symbol: CD1B
Name: CD1b molecule
RGD ID: 1348815
HGNC Page HGNC:1635
Description: Predicted to enable endogenous lipid antigen binding activity; exogenous lipid antigen binding activity; and lipopeptide binding activity. Predicted to be involved in several processes, including antigen processing and presentation, endogenous lipid antigen via MHC class Ib; antigen processing and presentation, exogenous lipid antigen via MHC class Ib; and positive regulation of T cell mediated cytotoxicity. Located in Golgi apparatus and cytosol.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: CD1; CD1A; CD1B antigen, b polypeptide; cortical thymocyte antigen CD1B; differentiation antigen CD1-alpha-3; MGC125990; MGC125991; R1; T-cell surface glycoprotein CD1b
RGD Orthologs
Bonobo
Dog
Pig
Green Monkey
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381158,285,405 - 158,331,531 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1158,327,951 - 158,331,531 (-)EnsemblGRCh38hg38GRCh38
GRCh371158,297,745 - 158,301,321 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361156,564,364 - 156,567,945 (-)NCBINCBI36Build 36hg18NCBI36
Build 341155,110,851 - 155,114,331NCBI
Celera1131,368,785 - 131,372,366 (-)NCBICelera
Cytogenetic Map1q23.1NCBI
HuRef1129,655,811 - 129,659,392 (-)NCBIHuRef
CHM1_11159,694,116 - 159,697,697 (-)NCBICHM1_1
T2T-CHM13v2.01157,422,502 - 157,468,624 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
References

References - curated
# Reference Title Reference Citation
1. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:2447586   PMID:2583117   PMID:2701945   PMID:3097645   PMID:7527500   PMID:7542404   PMID:8729450   PMID:10488738   PMID:10626896   PMID:10899914   PMID:11035089   PMID:11160317  
PMID:11580851   PMID:11847129   PMID:11938350   PMID:12049721   PMID:12118248   PMID:12415264   PMID:12477932   PMID:14551186   PMID:14716313   PMID:14764708   PMID:15032598   PMID:15489334  
PMID:15556687   PMID:15864273   PMID:15880118   PMID:16272286   PMID:16710414   PMID:16794581   PMID:16874306   PMID:17207965   PMID:18287231   PMID:18337560   PMID:18538591   PMID:18624350  
PMID:19004781   PMID:19454700   PMID:19808251   PMID:19948070   PMID:20212510   PMID:20237496   PMID:21807869   PMID:21873635   PMID:22087000   PMID:22782895   PMID:23468110   PMID:23677998  
PMID:23766460   PMID:23981064   PMID:24556395   PMID:26186194   PMID:26621732   PMID:27807341   PMID:28514442   PMID:29398561   PMID:30854633   PMID:32258122   PMID:33384157   PMID:33479373  
PMID:33961781   PMID:35013257  


Genomics

Comparative Map Data
CD1B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381158,285,405 - 158,331,531 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1158,327,951 - 158,331,531 (-)EnsemblGRCh38hg38GRCh38
GRCh371158,297,745 - 158,301,321 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361156,564,364 - 156,567,945 (-)NCBINCBI36Build 36hg18NCBI36
Build 341155,110,851 - 155,114,331NCBI
Celera1131,368,785 - 131,372,366 (-)NCBICelera
Cytogenetic Map1q23.1NCBI
HuRef1129,655,811 - 129,659,392 (-)NCBIHuRef
CHM1_11159,694,116 - 159,697,697 (-)NCBICHM1_1
T2T-CHM13v2.01157,422,502 - 157,468,624 (-)NCBIT2T-CHM13v2.0
CD1B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2191,516,972 - 91,520,549 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1191,260,880 - 91,264,457 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01133,686,155 - 133,689,732 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11137,476,898 - 137,480,471 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1137,476,898 - 137,480,471 (-)Ensemblpanpan1.1panPan2
CD1B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13823,316,203 - 23,319,767 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3823,312,217 - 23,315,768 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03823,447,693 - 23,451,270 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3823,426,584 - 23,462,931 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13823,197,837 - 23,201,384 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03823,745,550 - 23,749,137 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03824,152,889 - 24,156,442 (-)NCBIUU_Cfam_GSD_1.0
PCD1B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl492,031,712 - 92,040,742 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1492,035,122 - 92,040,724 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24100,378,316 - 100,383,517 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CD1B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1205,588,575 - 5,593,617 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl205,590,274 - 5,593,364 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660384,776,365 - 4,779,573 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in CD1B
42 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 1q23.1-25.1(chr1:157747246-176021247)x3 copy number gain See cases [RCV000051854] Chr1:157747246..176021247 [GRCh38]
Chr1:157717036..175990383 [GRCh37]
Chr1:155983660..174257006 [NCBI36]
Chr1:1q23.1-25.1		 pathogenic
GRCh38/hg38 1q23.1-23.3(chr1:156664483-160727411)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051851]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051851]|See cases [RCV000051851] Chr1:156664483..160727411 [GRCh38]
Chr1:156634275..160697201 [GRCh37]
Chr1:154900899..158963825 [NCBI36]
Chr1:1q23.1-23.3		 pathogenic
GRCh38/hg38 1q21.2-25.2(chr1:149854269-180267197)x3 copy number gain See cases [RCV000143515] Chr1:149854269..180267197 [GRCh38]
Chr1:149825831..180236332 [GRCh37]
Chr1:148092455..178502955 [NCBI36]
Chr1:1q21.2-25.2		 pathogenic
GRCh37/hg19 1p36.33-q44(chr1:849467-249224684)x3 copy number gain See cases [RCV000510383] Chr1:849467..249224684 [GRCh37]
Chr1:1p36.33-q44		 pathogenic
GRCh37/hg19 1p36.33-q44(chr1:849467-249224684) copy number gain See cases [RCV000510926] Chr1:849467..249224684 [GRCh37]
Chr1:1p36.33-q44		 pathogenic
NM_001764.3(CD1B):c.350T>G (p.Ile117Arg) single nucleotide variant Inborn genetic diseases [RCV003249294] Chr1:158330109 [GRCh38]
Chr1:158299899 [GRCh37]
Chr1:1q23.1		 uncertain significance
NM_001765.3(CD1C):c.65C>T (p.Ser22Phe) single nucleotide variant Inborn genetic diseases [RCV003289627] Chr1:158291137 [GRCh38]
Chr1:158260927 [GRCh37]
Chr1:1q23.1		 uncertain significance
NM_001765.3(CD1C):c.16T>C (p.Phe6Leu) single nucleotide variant Inborn genetic diseases [RCV003273117] Chr1:158290080 [GRCh38]
Chr1:158259870 [GRCh37]
Chr1:1q23.1		 likely benign
NM_001765.3(CD1C):c.860T>G (p.Leu287Arg) single nucleotide variant Inborn genetic diseases [RCV003255219] Chr1:158292845 [GRCh38]
Chr1:158262635 [GRCh37]
Chr1:1q23.1		 uncertain significance
GRCh37/hg19 1q23.1-24.2(chr1:157321299-167391423)x1 copy number loss not provided [RCV000848773] Chr1:157321299..167391423 [GRCh37]
Chr1:1q23.1-24.2		 pathogenic
GRCh37/hg19 1p36.33-q44(chr1:82154-249218992)x3 copy number gain not provided [RCV000736305] Chr1:82154..249218992 [GRCh37]
Chr1:1p36.33-q44		 pathogenic
GRCh37/hg19 1p36.33-q44(chr1:47851-249228449)x3 copy number gain not provided [RCV000736295] Chr1:47851..249228449 [GRCh37]
Chr1:1p36.33-q44		 pathogenic
NM_001765.3(CD1C):c.69G>A (p.Gln23=) single nucleotide variant not provided [RCV000967810] Chr1:158291141 [GRCh38]
Chr1:158260931 [GRCh37]
Chr1:1q23.1		 benign
NM_001765.3(CD1C):c.954C>A (p.Val318=) single nucleotide variant not provided [RCV000888620] Chr1:158293276 [GRCh38]
Chr1:158263066 [GRCh37]
Chr1:1q23.1		 benign
NM_001765.3(CD1C):c.848G>C (p.Arg283Thr) single nucleotide variant not provided [RCV000880720] Chr1:158292833 [GRCh38]
Chr1:158262623 [GRCh37]
Chr1:1q23.1		 likely benign
NM_001764.3(CD1B):c.310G>A (p.Gly104Ser) single nucleotide variant not provided [RCV000949654] Chr1:158330814 [GRCh38]
Chr1:158300604 [GRCh37]
Chr1:1q23.1		 benign
NM_001765.3(CD1C):c.844G>T (p.Val282Leu) single nucleotide variant not provided [RCV000907922] Chr1:158292829 [GRCh38]
Chr1:158262619 [GRCh37]
Chr1:1q23.1		 likely benign
NM_001765.3(CD1C):c.899T>C (p.Phe300Ser) single nucleotide variant not provided [RCV000953430] Chr1:158293221 [GRCh38]
Chr1:158263011 [GRCh37]
Chr1:1q23.1		 benign
NM_001764.3(CD1B):c.739G>A (p.Gly247Ser) single nucleotide variant not provided [RCV000955796] Chr1:158329517 [GRCh38]
Chr1:158299307 [GRCh37]
Chr1:1q23.1		 benign
NM_001764.3(CD1B):c.228T>C (p.Phe76=) single nucleotide variant not provided [RCV000955797] Chr1:158330896 [GRCh38]
Chr1:158300686 [GRCh37]
Chr1:1q23.1		 benign
NC_000001.10:g.(?_130980840)_(248900000_?)dup duplication Gastrointestinal stromal tumor [RCV001300221]|Parathyroid carcinoma [RCV001341077] Chr1:130980840..248900000 [GRCh37]
Chr1:1q12-44		 uncertain significance
NM_001765.3(CD1C):c.589A>G (p.Lys197Glu) single nucleotide variant Inborn genetic diseases [RCV003198577] Chr1:158292344 [GRCh38]
Chr1:158262134 [GRCh37]
Chr1:1q23.1		 uncertain significance
GRCh37/hg19 1q23.1(chr1:158167184-158427171)x3 copy number gain not provided [RCV002474940] Chr1:158167184..158427171 [GRCh37]
Chr1:1q23.1		 uncertain significance
NM_001765.3(CD1C):c.944T>C (p.Ile315Thr) single nucleotide variant Inborn genetic diseases [RCV002991009] Chr1:158293266 [GRCh38]
Chr1:158263056 [GRCh37]
Chr1:1q23.1		 uncertain significance
NM_001765.3(CD1C):c.353C>T (p.Ala118Val) single nucleotide variant Inborn genetic diseases [RCV002754337] Chr1:158292108 [GRCh38]
Chr1:158261898 [GRCh37]
Chr1:1q23.1		 uncertain significance
NM_001765.3(CD1C):c.323C>T (p.Ser108Leu) single nucleotide variant Inborn genetic diseases [RCV002689266] Chr1:158291395 [GRCh38]
Chr1:158261185 [GRCh37]
Chr1:1q23.1		 uncertain significance
NM_001764.3(CD1B):c.839G>A (p.Arg280Gln) single nucleotide variant Inborn genetic diseases [RCV002683460] Chr1:158329417 [GRCh38]
Chr1:158299207 [GRCh37]
Chr1:1q23.1		 uncertain significance
NM_001764.3(CD1B):c.613C>T (p.Pro205Ser) single nucleotide variant Inborn genetic diseases [RCV002907439] Chr1:158329643 [GRCh38]
Chr1:158299433 [GRCh37]
Chr1:1q23.1		 uncertain significance
NM_001765.3(CD1C):c.175G>C (p.Asp59His) single nucleotide variant Inborn genetic diseases [RCV002945317] Chr1:158291247 [GRCh38]
Chr1:158261037 [GRCh37]
Chr1:1q23.1		 uncertain significance
NM_001765.3(CD1C):c.378G>T (p.Lys126Asn) single nucleotide variant Inborn genetic diseases [RCV002686678] Chr1:158292133 [GRCh38]
Chr1:158261923 [GRCh37]
Chr1:1q23.1		 uncertain significance
NM_001764.3(CD1B):c.656G>A (p.Arg219His) single nucleotide variant Inborn genetic diseases [RCV002968730] Chr1:158329600 [GRCh38]
Chr1:158299390 [GRCh37]
Chr1:1q23.1		 uncertain significance
NM_001764.3(CD1B):c.110C>T (p.Thr37Ile) single nucleotide variant Inborn genetic diseases [RCV002906718] Chr1:158331014 [GRCh38]
Chr1:158300804 [GRCh37]
Chr1:1q23.1		 uncertain significance
NM_001765.3(CD1C):c.701C>T (p.Pro234Leu) single nucleotide variant Inborn genetic diseases [RCV002696391] Chr1:158292686 [GRCh38]
Chr1:158262476 [GRCh37]
Chr1:1q23.1		 uncertain significance
NM_001765.3(CD1C):c.685G>A (p.Gly229Ser) single nucleotide variant Inborn genetic diseases [RCV002659870] Chr1:158292670 [GRCh38]
Chr1:158262460 [GRCh37]
Chr1:1q23.1		 uncertain significance
NM_001764.3(CD1B):c.397A>T (p.Arg133Trp) single nucleotide variant Inborn genetic diseases [RCV002886730] Chr1:158330062 [GRCh38]
Chr1:158299852 [GRCh37]
Chr1:1q23.1		 uncertain significance
NM_001764.3(CD1B):c.989A>G (p.Gln330Arg) single nucleotide variant Inborn genetic diseases [RCV002767661] Chr1:158328249 [GRCh38]
Chr1:158298039 [GRCh37]
Chr1:1q23.1		 uncertain significance
NM_001765.3(CD1C):c.820G>A (p.Glu274Lys) single nucleotide variant Inborn genetic diseases [RCV002983821] Chr1:158292805 [GRCh38]
Chr1:158262595 [GRCh37]
Chr1:1q23.1		 uncertain significance
NM_001765.3(CD1C):c.478C>G (p.Gln160Glu) single nucleotide variant Inborn genetic diseases [RCV002826066] Chr1:158292233 [GRCh38]
Chr1:158262023 [GRCh37]
Chr1:1q23.1		 uncertain significance
NM_001764.3(CD1B):c.898T>C (p.Ser300Pro) single nucleotide variant Inborn genetic diseases [RCV003003832] Chr1:158329003 [GRCh38]
Chr1:158298793 [GRCh37]
Chr1:1q23.1		 uncertain significance
NM_001765.3(CD1C):c.320A>T (p.Tyr107Phe) single nucleotide variant Inborn genetic diseases [RCV002745154] Chr1:158291392 [GRCh38]
Chr1:158261182 [GRCh37]
Chr1:1q23.1		 uncertain significance
NM_001765.3(CD1C):c.866G>A (p.Gly289Asp) single nucleotide variant Inborn genetic diseases [RCV002812857] Chr1:158292851 [GRCh38]
Chr1:158262641 [GRCh37]
Chr1:1q23.1		 likely benign
NM_001765.3(CD1C):c.800T>C (p.Ile267Thr) single nucleotide variant Inborn genetic diseases [RCV002648252] Chr1:158292785 [GRCh38]
Chr1:158262575 [GRCh37]
Chr1:1q23.1		 likely benign
NM_001765.3(CD1C):c.491A>G (p.His164Arg) single nucleotide variant Inborn genetic diseases [RCV002878238] Chr1:158292246 [GRCh38]
Chr1:158262036 [GRCh37]
Chr1:1q23.1		 uncertain significance
NM_001765.3(CD1C):c.970A>G (p.Lys324Glu) single nucleotide variant Inborn genetic diseases [RCV002896652] Chr1:158293292 [GRCh38]
Chr1:158263082 [GRCh37]
Chr1:1q23.1		 uncertain significance
NM_001764.3(CD1B):c.719G>A (p.Arg240Gln) single nucleotide variant Inborn genetic diseases [RCV003180954] Chr1:158329537 [GRCh38]
Chr1:158299327 [GRCh37]
Chr1:1q23.1		 likely benign
NM_001765.3(CD1C):c.950T>C (p.Ile317Thr) single nucleotide variant Inborn genetic diseases [RCV003177968] Chr1:158293272 [GRCh38]
Chr1:158263062 [GRCh37]
Chr1:1q23.1		 uncertain significance
NM_001765.3(CD1C):c.830G>A (p.Gly277Asp) single nucleotide variant Inborn genetic diseases [RCV003189373] Chr1:158292815 [GRCh38]
Chr1:158262605 [GRCh37]
Chr1:1q23.1		 uncertain significance
NM_001764.3(CD1B):c.656G>C (p.Arg219Pro) single nucleotide variant Inborn genetic diseases [RCV003205099] Chr1:158329600 [GRCh38]
Chr1:158299390 [GRCh37]
Chr1:1q23.1		 uncertain significance
NM_001764.3(CD1B):c.579T>A (p.Asn193Lys) single nucleotide variant Inborn genetic diseases [RCV003359068] Chr1:158329880 [GRCh38]
Chr1:158299670 [GRCh37]
Chr1:1q23.1		 uncertain significance
NM_001764.3(CD1B):c.253G>A (p.Glu85Lys) single nucleotide variant Inborn genetic diseases [RCV003347863] Chr1:158330871 [GRCh38]
Chr1:158300661 [GRCh37]
Chr1:1q23.1		 uncertain significance
GRCh37/hg19 1q23.1-23.3(chr1:158001058-162858285)x1 copy number loss not provided [RCV003483944] Chr1:158001058..162858285 [GRCh37]
Chr1:1q23.1-23.3		 likely pathogenic
GRCh37/hg19 1q21.1-23.1(chr1:144368497-158992086)x3 copy number gain not specified [RCV003986717] Chr1:144368497..158992086 [GRCh37]
Chr1:1q21.1-23.1		 pathogenic
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:205
Count of miRNA genes:96
Interacting mature miRNAs:98
Transcripts:ENST00000368168, ENST00000451207
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
PMC105497P1  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371158,300,588 - 158,300,852UniSTSGRCh37
Build 361156,567,212 - 156,567,476RGDNCBI36
Celera1131,371,633 - 131,371,897RGD
Cytogenetic Map1q22-q23UniSTS
HuRef1129,658,659 - 129,658,923UniSTS
SHGC-12745  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371158,297,792 - 158,298,024UniSTSGRCh37
Build 361156,564,416 - 156,564,648RGDNCBI36
Celera1131,368,837 - 131,369,069RGD
Cytogenetic Map1q22-q23UniSTS
HuRef1129,655,863 - 129,656,095UniSTS
GeneMap99-G3 RH Map16012.0UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system adipose tissue appendage
High 1
Medium 1 6 1 15 1 2 2 5 1
Low 95 125 110 65 240 59 595 23 16 41 101 296 7 106 247
Below cutoff 1195 1469 581 281 870 167 1801 644 527 146 697 653 113 699 1082

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001764 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011510119 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017002784 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017002785 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017002786 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054339536 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054339537 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054339538 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF142666 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH002634 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI336342 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK303329 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK303330 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK310617 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL121986 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AP002532 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC069481 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC074747 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC104216 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC104217 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CD687240 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471121 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068277 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M14665 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M28826 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000368168   ⟹   ENSP00000357150
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1158,327,955 - 158,331,531 (-)Ensembl
RefSeq Acc Id: ENST00000451207   ⟹   ENSP00000395161
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1158,327,951 - 158,331,025 (-)Ensembl
RefSeq Acc Id: NM_001764   ⟹   NP_001755
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381158,327,955 - 158,331,531 (-)NCBI
GRCh371158,297,740 - 158,301,321 (-)ENTREZGENE
Build 361156,564,364 - 156,567,945 (-)NCBI Archive
HuRef1129,655,811 - 129,659,392 (-)ENTREZGENE
CHM1_11159,694,116 - 159,697,697 (-)NCBI
T2T-CHM13v2.01157,465,048 - 157,468,624 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011510119   ⟹   XP_011508421
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381158,327,955 - 158,331,531 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017002784   ⟹   XP_016858273
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381158,294,506 - 158,331,531 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017002785   ⟹   XP_016858274
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381158,285,405 - 158,331,531 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017002786   ⟹   XP_016858275
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381158,327,955 - 158,331,531 (-)NCBI
Sequence:
RefSeq Acc Id: XM_054339536   ⟹   XP_054195511
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01157,465,048 - 157,468,624 (-)NCBI
RefSeq Acc Id: XM_054339537   ⟹   XP_054195512
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01157,422,502 - 157,468,624 (-)NCBI
RefSeq Acc Id: XM_054339538   ⟹   XP_054195513
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01157,465,048 - 157,468,624 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_001755   ⟸   NM_001764
- Peptide Label: precursor
- UniProtKB: Q5TDL0 (UniProtKB/Swiss-Prot),   Q5TDK9 (UniProtKB/Swiss-Prot),   Q9UMM2 (UniProtKB/Swiss-Prot),   P29016 (UniProtKB/Swiss-Prot),   B4E0D3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011508421   ⟸   XM_011510119
- Peptide Label: isoform X1
- UniProtKB: H7C0I2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_016858274   ⟸   XM_017002785
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_016858273   ⟸   XM_017002784
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_016858275   ⟸   XM_017002786
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: ENSP00000395161   ⟸   ENST00000451207
RefSeq Acc Id: ENSP00000357150   ⟸   ENST00000368168
RefSeq Acc Id: XP_054195512   ⟸   XM_054339537
- Peptide Label: isoform X3
RefSeq Acc Id: XP_054195513   ⟸   XM_054339538
- Peptide Label: isoform X4
RefSeq Acc Id: XP_054195511   ⟸   XM_054339536
- Peptide Label: isoform X1
Protein Domains
Ig-like   MHC class I-like antigen recognition-like

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P29016-F1-model_v2 AlphaFold P29016 1-333 view protein structure

Promoters
RGD ID:6857690
Promoter ID:EPDNEW_H2010
Type:initiation region
Name:CD1B_1
Description:CD1b molecule
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381158,331,531 - 158,331,591EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:1635 AgrOrtholog
COSMIC CD1B COSMIC
Ensembl Genes ENSG00000158485 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000368168 ENTREZGENE
  ENST00000368168.4 UniProtKB/Swiss-Prot
  ENST00000451207 ENTREZGENE
  ENST00000451207.5 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.30.500.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000158485 GTEx
HGNC ID HGNC:1635 ENTREZGENE
Human Proteome Map CD1B Human Proteome Map
InterPro Ig-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_C1-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MHC_I-like_Ag-recog UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MHC_I-like_Ag-recog_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MHC_I/II-like_Ag-recog UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:910 UniProtKB/Swiss-Prot
NCBI Gene 910 ENTREZGENE
OMIM 188360 OMIM
PANTHER MHC CLASS I-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  T-CELL SURFACE GLYCOPROTEIN CD1B UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam C1-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MHC_I_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB CD1B RGD, PharmGKB
PROSITE IG_LIKE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART IGc1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF54452 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt B4E0D3 ENTREZGENE, UniProtKB/TrEMBL
  CD1B_HUMAN UniProtKB/Swiss-Prot
  H7C0I2 ENTREZGENE, UniProtKB/TrEMBL
  P29016 ENTREZGENE
  Q5TDK9 ENTREZGENE
  Q5TDL0 ENTREZGENE
  Q9UMM2 ENTREZGENE
  Q9UN97_HUMAN UniProtKB/TrEMBL
UniProt Secondary Q5TDK9 UniProtKB/Swiss-Prot
  Q5TDL0 UniProtKB/Swiss-Prot
  Q9UMM2 UniProtKB/Swiss-Prot