ZNF551 (zinc finger protein 551) - Rat Genome Database

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Gene: ZNF551 (zinc finger protein 551) Homo sapiens
Analyze
Symbol: ZNF551
Name: zinc finger protein 551
RGD ID: 1348729
HGNC Page HGNC:25108
Description: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: DKFZp686H1038; KOX 23 protein (56 AA); MGC52307; zinc finger protein KOX23
RGD Orthologs
Mouse
Rat
Bonobo
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381957,681,977 - 57,690,648 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1957,681,969 - 57,717,301 (+)EnsemblGRCh38hg38GRCh38
GRCh371958,193,345 - 58,202,016 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361962,885,217 - 62,892,991 (+)NCBINCBI36Build 36hg18NCBI36
Build 341962,885,216 - 62,892,979NCBI
Celera1955,236,894 - 55,244,716 (+)NCBICelera
Cytogenetic Map19q13.43NCBI
HuRef1954,505,720 - 54,513,562 (+)NCBIHuRef
CHM1_11958,187,212 - 58,195,054 (+)NCBICHM1_1
T2T-CHM13v2.01960,778,907 - 60,787,580 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleus  (IBA,IEA)

References

References - curated
# Reference Title Reference Citation
1. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:2288909   PMID:14702039   PMID:15302935   PMID:15489334   PMID:19274049   PMID:21873635   PMID:29180619  


Genomics

Comparative Map Data
ZNF551
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381957,681,977 - 57,690,648 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1957,681,969 - 57,717,301 (+)EnsemblGRCh38hg38GRCh38
GRCh371958,193,345 - 58,202,016 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361962,885,217 - 62,892,991 (+)NCBINCBI36Build 36hg18NCBI36
Build 341962,885,216 - 62,892,979NCBI
Celera1955,236,894 - 55,244,716 (+)NCBICelera
Cytogenetic Map19q13.43NCBI
HuRef1954,505,720 - 54,513,562 (+)NCBIHuRef
CHM1_11958,187,212 - 58,195,054 (+)NCBICHM1_1
T2T-CHM13v2.01960,778,907 - 60,787,580 (+)NCBIT2T-CHM13v2.0
Zfp551
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39712,146,476 - 12,156,685 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl712,149,080 - 12,156,678 (-)EnsemblGRCm39 Ensembl
GRCm38712,412,549 - 12,422,739 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl712,415,153 - 12,422,751 (-)EnsemblGRCm38mm10GRCm38
MGSCv37713,000,497 - 13,007,840 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36711,321,015 - 11,328,355 (-)NCBIMGSCv36mm8
Celera710,044,941 - 10,052,284 (-)NCBICelera
Cytogenetic Map7A1NCBI
cM Map77.5NCBI
Zfp551
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8181,615,977 - 81,626,233 (-)NCBIGRCr8
mRatBN7.2172,543,815 - 72,554,060 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl172,540,108 - 72,554,071 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0166,894,836 - 66,908,849 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl166,898,946 - 66,904,539 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0167,682,376 - 67,692,511 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera161,230,696 - 61,310,180 (+)NCBICelera
Cytogenetic Map1q21NCBI
ZNF551
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22063,961,829 - 63,970,957 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11965,749,450 - 65,758,525 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01954,693,901 - 54,702,968 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11963,523,112 - 63,531,228 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1963,523,118 - 63,557,784 (+)Ensemblpanpan1.1panPan2
LOC106504178
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1662,590,163 - 62,615,161 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2657,195,208 - 57,211,746 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ZNF551
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1650,037,266 - 50,050,747 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660453,296,978 - 3,306,250 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Znf551
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624832596,160 - 611,112 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in ZNF551
28 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 19q13.33-13.43(chr19:50191219-58535818)x3 copy number gain See cases [RCV000050883] Chr19:50191219..58535818 [GRCh38]
Chr19:50694476..59047185 [GRCh37]
Chr19:55386288..63738997 [NCBI36]
Chr19:19q13.33-13.43		 pathogenic
GRCh38/hg38 19q13.33-13.43(chr19:49907832-58557889)x3 copy number gain See cases [RCV000052925] Chr19:49907832..58557889 [GRCh38]
Chr19:50411089..59069256 [GRCh37]
Chr19:55102901..63761068 [NCBI36]
Chr19:19q13.33-13.43		 pathogenic
GRCh38/hg38 19q13.41-13.43(chr19:51141518-58539965)x3 copy number gain See cases [RCV000052926] Chr19:51141518..58539965 [GRCh38]
Chr19:51644775..59051332 [GRCh37]
Chr19:56336587..63743144 [NCBI36]
Chr19:19q13.41-13.43		 pathogenic
GRCh38/hg38 19q13.33-13.43(chr19:47908540-58539965)x3 copy number gain See cases [RCV000052914] Chr19:47908540..58539965 [GRCh38]
Chr19:48411797..59051332 [GRCh37]
Chr19:53103609..63743144 [NCBI36]
Chr19:19q13.33-13.43		 pathogenic
GRCh38/hg38 19q13.33-13.43(chr19:47929575-58572206)x3 copy number gain See cases [RCV000052915] Chr19:47929575..58572206 [GRCh38]
Chr19:48432832..59083573 [GRCh37]
Chr19:53124644..63775385 [NCBI36]
Chr19:19q13.33-13.43		 pathogenic
GRCh38/hg38 19q13.43(chr19:57674103-57871262)x3 copy number gain See cases [RCV000052595] Chr19:57674103..57871262 [GRCh38]
Chr19:58185471..58382630 [GRCh37]
Chr19:62877283..63074442 [NCBI36]
Chr19:19q13.43		 uncertain significance
GRCh38/hg38 19q13.41-13.43(chr19:52612432-58581203)x3 copy number gain See cases [RCV000134174] Chr19:52612432..58581203 [GRCh38]
Chr19:53115685..59092570 [GRCh37]
Chr19:57807497..63784382 [NCBI36]
Chr19:19q13.41-13.43		 pathogenic
GRCh38/hg38 19q13.41-13.43(chr19:52955056-58581203)x3 copy number gain See cases [RCV000134139] Chr19:52955056..58581203 [GRCh38]
Chr19:53458309..59092570 [GRCh37]
Chr19:58150121..63784382 [NCBI36]
Chr19:19q13.41-13.43		 pathogenic
GRCh38/hg38 19q13.33-13.43(chr19:50152520-58581203)x3 copy number gain See cases [RCV000135843] Chr19:50152520..58581203 [GRCh38]
Chr19:50655777..59092570 [GRCh37]
Chr19:55347589..63784382 [NCBI36]
Chr19:19q13.33-13.43		 pathogenic
GRCh38/hg38 19q13.43(chr19:56363208-58581203)x3 copy number gain See cases [RCV000052927] Chr19:56363208..58581203 [GRCh38]
Chr19:56874577..59092570 [GRCh37]
Chr19:61566389..63784382 [NCBI36]
Chr19:19q13.43		 pathogenic
NM_152677.2(ZSCAN4):c.588G>A (p.Trp196Ter) single nucleotide variant Malignant melanoma [RCV000072414] Chr19:57678191 [GRCh38]
Chr19:58189559 [GRCh37]
Chr19:62881371 [NCBI36]
Chr19:19q13.43		 not provided
NM_152677.2(ZSCAN4):c.600G>A (p.Ser200=) single nucleotide variant Malignant melanoma [RCV000072415] Chr19:57678203 [GRCh38]
Chr19:58189571 [GRCh37]
Chr19:62881383 [NCBI36]
Chr19:19q13.43		 not provided
GRCh38/hg38 19q13.43(chr19:57546443-57889946)x3 copy number gain See cases [RCV000141360] Chr19:57546443..57889946 [GRCh38]
Chr19:58057811..58401314 [GRCh37]
Chr19:62749623..63093126 [NCBI36]
Chr19:19q13.43		 uncertain significance
GRCh38/hg38 19q13.41-13.43(chr19:52143873-58445521)x3 copy number gain See cases [RCV000142008] Chr19:52143873..58445521 [GRCh38]
Chr19:52647126..58956888 [GRCh37]
Chr19:57338938..63648700 [NCBI36]
Chr19:19q13.41-13.43		 pathogenic
GRCh38/hg38 19q13.43(chr19:56353449-58445521)x3 copy number gain See cases [RCV000141900] Chr19:56353449..58445521 [GRCh38]
Chr19:56864818..58956888 [GRCh37]
Chr19:61556630..63648700 [NCBI36]
Chr19:19q13.43		 uncertain significance
GRCh37/hg19 19q13.33-13.43(chr19:50489390-59095359)x3 copy number gain See cases [RCV000445925] Chr19:50489390..59095359 [GRCh37]
Chr19:19q13.33-13.43		 pathogenic
GRCh37/hg19 19q13.43(chr19:58026984-58246176)x1 copy number loss See cases [RCV000512135] Chr19:58026984..58246176 [GRCh37]
Chr19:19q13.43		 uncertain significance
GRCh37/hg19 19q13.43(chr19:56706500-58956888)x3 copy number gain See cases [RCV000512396] Chr19:56706500..58956888 [GRCh37]
Chr19:19q13.43		 uncertain significance
GRCh37/hg19 19q13.42-13.43(chr19:54344821-58956888)x3 copy number gain See cases [RCV000448186] Chr19:54344821..58956888 [GRCh37]
Chr19:19q13.42-13.43		 pathogenic
GRCh37/hg19 19p13.3-q13.43(chr19:260912-58956888) copy number gain See cases [RCV000512296] Chr19:260912..58956888 [GRCh37]
Chr19:19p13.3-q13.43		 pathogenic
NM_138347.5(ZNF551):c.82G>C (p.Gly28Arg) single nucleotide variant Inborn genetic diseases [RCV003256839] Chr19:57685262 [GRCh38]
Chr19:58196630 [GRCh37]
Chr19:19q13.43		 uncertain significance
GRCh37/hg19 19p13.3-q13.43(chr19:260912-58956888)x3 copy number gain See cases [RCV000511289] Chr19:260912..58956888 [GRCh37]
Chr19:19p13.3-q13.43		 pathogenic|uncertain significance
Single allele duplication not provided [RCV000677936] Chr19:57953199..58196644 [GRCh37]
Chr19:19q13.43		 uncertain significance
GRCh37/hg19 19q13.43(chr19:57891243-58536930)x3 copy number gain not provided [RCV000684084] Chr19:57891243..58536930 [GRCh37]
Chr19:19q13.43		 likely benign
GRCh37/hg19 19q13.42-13.43(chr19:54196216-58759679)x3 copy number gain not provided [RCV000684095] Chr19:54196216..58759679 [GRCh37]
Chr19:19q13.42-13.43		 pathogenic
GRCh37/hg19 19p13.3-q13.43(chr19:260912-59097160)x3 copy number gain not provided [RCV000752444] Chr19:260912..59097160 [GRCh37]
Chr19:19p13.3-q13.43		 pathogenic
GRCh37/hg19 19q13.33-13.43(chr19:50740074-59097160)x3 copy number gain not provided [RCV000740208] Chr19:50740074..59097160 [GRCh37]
Chr19:19q13.33-13.43		 pathogenic
NM_138347.5(ZNF551):c.934C>T (p.Arg312Cys) single nucleotide variant Inborn genetic diseases [RCV003244898] Chr19:57687209 [GRCh38]
Chr19:58198577 [GRCh37]
Chr19:19q13.43		 likely benign
GRCh37/hg19 19q13.43(chr19:58092045-58686148)x3 copy number gain not provided [RCV000849080] Chr19:58092045..58686148 [GRCh37]
Chr19:19q13.43		 uncertain significance
GRCh37/hg19 19q13.43(chr19:57952073-58661581)x3 copy number gain not provided [RCV000846105] Chr19:57952073..58661581 [GRCh37]
Chr19:19q13.43		 uncertain significance
GRCh37/hg19 19q13.43(chr19:58054819-58410552)x3 copy number gain not provided [RCV000848932] Chr19:58054819..58410552 [GRCh37]
Chr19:19q13.43		 uncertain significance
GRCh37/hg19 19q13.43(chr19:58026985-58255427)x3 copy number gain not provided [RCV001832942] Chr19:58026985..58255427 [GRCh37]
Chr19:19q13.43		 likely benign
NM_138347.5(ZNF551):c.310A>C (p.Ser104Arg) single nucleotide variant Inborn genetic diseases [RCV002794434] Chr19:57686585 [GRCh38]
Chr19:58197953 [GRCh37]
Chr19:19q13.43		 uncertain significance
NM_138347.5(ZNF551):c.607G>A (p.Glu203Lys) single nucleotide variant Inborn genetic diseases [RCV002858996] Chr19:57686882 [GRCh38]
Chr19:58198250 [GRCh37]
Chr19:19q13.43		 uncertain significance
NM_138347.5(ZNF551):c.1289G>A (p.Cys430Tyr) single nucleotide variant Inborn genetic diseases [RCV002772446] Chr19:57687564 [GRCh38]
Chr19:58198932 [GRCh37]
Chr19:19q13.43		 uncertain significance
NM_138347.5(ZNF551):c.1868C>T (p.Pro623Leu) single nucleotide variant Inborn genetic diseases [RCV002733581] Chr19:57688143 [GRCh38]
Chr19:58199511 [GRCh37]
Chr19:19q13.43		 uncertain significance
NM_138347.5(ZNF551):c.1001G>A (p.Arg334His) single nucleotide variant Inborn genetic diseases [RCV002977973] Chr19:57687276 [GRCh38]
Chr19:58198644 [GRCh37]
Chr19:19q13.43		 uncertain significance
NM_138347.5(ZNF551):c.1564C>T (p.Arg522Trp) single nucleotide variant Inborn genetic diseases [RCV002887391] Chr19:57687839 [GRCh38]
Chr19:58199207 [GRCh37]
Chr19:19q13.43		 uncertain significance
NM_138347.5(ZNF551):c.1139G>A (p.Arg380Gln) single nucleotide variant Inborn genetic diseases [RCV002781593] Chr19:57687414 [GRCh38]
Chr19:58198782 [GRCh37]
Chr19:19q13.43		 uncertain significance
NM_138347.5(ZNF551):c.588C>G (p.His196Gln) single nucleotide variant Inborn genetic diseases [RCV002983947] Chr19:57686863 [GRCh38]
Chr19:58198231 [GRCh37]
Chr19:19q13.43		 uncertain significance
NM_138347.5(ZNF551):c.1093T>G (p.Cys365Gly) single nucleotide variant Inborn genetic diseases [RCV002984617] Chr19:57687368 [GRCh38]
Chr19:58198736 [GRCh37]
Chr19:19q13.43		 uncertain significance
NM_138347.5(ZNF551):c.1685G>A (p.Ser562Asn) single nucleotide variant Inborn genetic diseases [RCV002698425] Chr19:57687960 [GRCh38]
Chr19:58199328 [GRCh37]
Chr19:19q13.43		 uncertain significance
NM_138347.5(ZNF551):c.746G>A (p.Gly249Glu) single nucleotide variant Inborn genetic diseases [RCV002940716] Chr19:57687021 [GRCh38]
Chr19:58198389 [GRCh37]
Chr19:19q13.43		 uncertain significance
NM_138347.5(ZNF551):c.1457G>A (p.Arg486His) single nucleotide variant Inborn genetic diseases [RCV002964226] Chr19:57687732 [GRCh38]
Chr19:58199100 [GRCh37]
Chr19:19q13.43		 uncertain significance
NM_138347.5(ZNF551):c.1971C>A (p.Asn657Lys) single nucleotide variant Inborn genetic diseases [RCV002702854] Chr19:57688246 [GRCh38]
Chr19:58199614 [GRCh37]
Chr19:19q13.43		 uncertain significance
NM_138347.5(ZNF551):c.1687G>C (p.Glu563Gln) single nucleotide variant Inborn genetic diseases [RCV002719461] Chr19:57687962 [GRCh38]
Chr19:58199330 [GRCh37]
Chr19:19q13.43		 uncertain significance
NM_138347.5(ZNF551):c.720G>C (p.Gln240His) single nucleotide variant Inborn genetic diseases [RCV002722713] Chr19:57686995 [GRCh38]
Chr19:58198363 [GRCh37]
Chr19:19q13.43		 uncertain significance
NM_138347.5(ZNF551):c.1259A>G (p.Gln420Arg) single nucleotide variant Inborn genetic diseases [RCV003206890] Chr19:57687534 [GRCh38]
Chr19:58198902 [GRCh37]
Chr19:19q13.43		 uncertain significance
NM_138347.5(ZNF551):c.1658A>C (p.His553Pro) single nucleotide variant Inborn genetic diseases [RCV003186384] Chr19:57687933 [GRCh38]
Chr19:58199301 [GRCh37]
Chr19:19q13.43		 uncertain significance
NM_138347.5(ZNF551):c.895A>G (p.Ile299Val) single nucleotide variant Inborn genetic diseases [RCV003213017] Chr19:57687170 [GRCh38]
Chr19:58198538 [GRCh37]
Chr19:19q13.43		 uncertain significance
NM_138347.5(ZNF551):c.1423T>C (p.Tyr475His) single nucleotide variant Inborn genetic diseases [RCV003352272] Chr19:57687698 [GRCh38]
Chr19:58199066 [GRCh37]
Chr19:19q13.43		 uncertain significance
NM_138347.5(ZNF551):c.643G>A (p.Ala215Thr) single nucleotide variant Inborn genetic diseases [RCV003366168] Chr19:57686918 [GRCh38]
Chr19:58198286 [GRCh37]
Chr19:19q13.43		 uncertain significance
NM_138347.5(ZNF551):c.1937G>A (p.Ser646Asn) single nucleotide variant Inborn genetic diseases [RCV003350016] Chr19:57688212 [GRCh38]
Chr19:58199580 [GRCh37]
Chr19:19q13.43		 uncertain significance
NM_138347.5(ZNF551):c.80A>G (p.Gln27Arg) single nucleotide variant Inborn genetic diseases [RCV003374190] Chr19:57682243 [GRCh38]
Chr19:58193611 [GRCh37]
Chr19:19q13.43		 uncertain significance
NM_138347.5(ZNF551):c.1773A>T (p.Glu591Asp) single nucleotide variant Inborn genetic diseases [RCV003368506] Chr19:57688048 [GRCh38]
Chr19:58199416 [GRCh37]
Chr19:19q13.43		 uncertain significance
NM_138347.5(ZNF551):c.562C>G (p.Pro188Ala) single nucleotide variant Inborn genetic diseases [RCV003383916] Chr19:57686837 [GRCh38]
Chr19:58198205 [GRCh37]
Chr19:19q13.43		 uncertain significance
GRCh37/hg19 19q13.43(chr19:58034484-58421498)x3 copy number gain not provided [RCV003485203] Chr19:58034484..58421498 [GRCh37]
Chr19:19q13.43		 uncertain significance
GRCh37/hg19 19q13.43(chr19:58186264-58449066)x3 copy number gain not provided [RCV003485204] Chr19:58186264..58449066 [GRCh37]
Chr19:19q13.43		 uncertain significance
NM_138347.5(ZNF551):c.620G>C (p.Ser207Thr) single nucleotide variant Inborn genetic diseases [RCV002688679] Chr19:57686895 [GRCh38]
Chr19:58198263 [GRCh37]
Chr19:19q13.43		 uncertain significance
GRCh37/hg19 19p13.3-q13.43(chr19:68029-59110290)x3 copy number gain not provided [RCV000752439] Chr19:68029..59110290 [GRCh37]
Chr19:19p13.3-q13.43		 pathogenic
NM_138347.5(ZNF551):c.1223G>A (p.Arg408Gln) single nucleotide variant Inborn genetic diseases [RCV003251977] Chr19:57687498 [GRCh38]
Chr19:58198866 [GRCh37]
Chr19:19q13.43		 uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1861
Count of miRNA genes:825
Interacting mature miRNAs:943
Transcripts:ENST00000282296, ENST00000356715, ENST00000599402, ENST00000601064
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
WI-13703  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371958,198,383 - 58,198,532UniSTSGRCh37
Build 361962,890,195 - 62,890,344RGDNCBI36
Celera1955,241,920 - 55,242,069RGD
Cytogenetic Map19q13.43UniSTS
HuRef1954,510,766 - 54,510,915UniSTS
GeneMap99-GB4 RH Map19289.61UniSTS
Whitehead-RH Map19366.5UniSTS
NCBI RH Map19600.5UniSTS
RH12298  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371958,199,828 - 58,200,045UniSTSGRCh37
Build 361962,891,640 - 62,891,857RGDNCBI36
Celera1955,243,365 - 55,243,582RGD
Cytogenetic Map19q13.43UniSTS
HuRef1954,512,211 - 54,512,428UniSTS
GeneMap99-GB4 RH Map19287.74UniSTS
NCBI RH Map19600.5UniSTS
D19S675E  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371958,198,381 - 58,198,465UniSTSGRCh37
Build 361962,890,193 - 62,890,277RGDNCBI36
Celera1955,241,918 - 55,242,002RGD
Cytogenetic Map19q13.43UniSTS
HuRef1954,510,764 - 54,510,848UniSTS
GeneMap99-GB4 RH Map19292.71UniSTS
NCBI RH Map19600.5UniSTS
SHGC-67307  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map15q22.3UniSTS
Cytogenetic Map20q13.3UniSTS
Cytogenetic Map7q11.23UniSTS
Cytogenetic Map7p13UniSTS
Cytogenetic Map19q13.32UniSTS
Cytogenetic Map19q13.43UniSTS
Cytogenetic Map3q21.2UniSTS
Cytogenetic Map3p21.3UniSTS
Cytogenetic Map18q11.2UniSTS
Cytogenetic Map19q13.3UniSTS
Cytogenetic MapXp11.3UniSTS
Cytogenetic Map7q21.2UniSTS
Cytogenetic Map13q14UniSTS
Cytogenetic Map19p13.3UniSTS
Cytogenetic Map18pter-p11.3UniSTS
Cytogenetic Map7p22.2UniSTS
Cytogenetic Map8q24.3UniSTS
Cytogenetic Map22q11.21UniSTS
Cytogenetic Map4q13.1UniSTS
Cytogenetic Map6p25UniSTS
Cytogenetic Map13q34UniSTS
Cytogenetic Map8q24.22UniSTS
Cytogenetic Map16q21UniSTS
Cytogenetic Map1p35.2UniSTS
Cytogenetic Map1q25.1UniSTS
Cytogenetic Map12q13.3UniSTS
Cytogenetic Map11q13UniSTS
Cytogenetic Map8q21.1UniSTS
Cytogenetic Map19q13.12UniSTS
Cytogenetic Map1p13.3UniSTS
Cytogenetic Map6q22.31UniSTS
Cytogenetic Map7p11.2UniSTS
Cytogenetic Map7q34UniSTS
Cytogenetic Map12q24.31UniSTS
Cytogenetic Map12q24.23UniSTS
Cytogenetic Map9p13.3UniSTS
Cytogenetic Map3p21.1UniSTS
Cytogenetic Map21q22.3UniSTS
Cytogenetic Map2q24.2UniSTS
Cytogenetic Map2p25.1-p24.1UniSTS
Cytogenetic Map5q32UniSTS
Cytogenetic Map5q31UniSTS
Cytogenetic Map19q13.4UniSTS
Cytogenetic Map16p13.3UniSTS
Cytogenetic Map16q22.2UniSTS
Cytogenetic Map1q32.2-q41UniSTS
Cytogenetic Map17q21.31UniSTS
Cytogenetic Map14q12UniSTS
Cytogenetic Map16q24.3UniSTS
Cytogenetic Map17q24.1UniSTS
Cytogenetic Map22q13.1UniSTS
Cytogenetic Map16p13UniSTS
Cytogenetic Map1q32UniSTS
Cytogenetic MapXp22.3UniSTS
Cytogenetic Map14q11.2UniSTS
Cytogenetic Map6p22.3UniSTS
Cytogenetic Map6p25.2UniSTS
Cytogenetic Map14q22.1UniSTS
Cytogenetic Map1p34.3UniSTS
Cytogenetic Map7q22.1UniSTS
Cytogenetic Map7p15.3UniSTS
Cytogenetic Map1q25.3UniSTS
Cytogenetic Map15q22.2UniSTS
Cytogenetic Map20q12UniSTS
Cytogenetic Map4p15.32UniSTS
Cytogenetic Map19q13.42UniSTS
Cytogenetic Map12q24.13UniSTS
Cytogenetic Map20q11.22UniSTS
Cytogenetic Map6p12.3UniSTS
Cytogenetic Map7q33UniSTS
Cytogenetic Map15q13.2UniSTS
Cytogenetic Map8q22.1UniSTS
Cytogenetic Map17q21UniSTS
Cytogenetic Map22q11.1UniSTS
Cytogenetic Map7q22UniSTS
Cytogenetic Map6q21UniSTS
Cytogenetic Map1p36.13UniSTS
Cytogenetic Map5p13.3UniSTS
Cytogenetic Map2p23.3UniSTS
Cytogenetic Map19q13UniSTS
Cytogenetic Map4q26UniSTS
Cytogenetic Map10q11.23UniSTS
Cytogenetic Map16p13.12UniSTS
Cytogenetic Map17q12UniSTS
Cytogenetic Map16q23.1UniSTS
Cytogenetic Map19p13.2UniSTS
Cytogenetic Map15q15.3UniSTS
Cytogenetic Map2q35UniSTS
Cytogenetic Map22q13.2UniSTS
Cytogenetic Map18q21.32UniSTS
Cytogenetic Map5q22.1UniSTS
Cytogenetic Map1p36.12UniSTS
Cytogenetic Map14q32.12UniSTS
Cytogenetic Map12q13UniSTS
Cytogenetic Map11q13.1UniSTS
Cytogenetic Map14q32.31UniSTS
Cytogenetic Map17q21.2UniSTS
Cytogenetic Map11q13.5UniSTS
Cytogenetic Map15q25.2UniSTS
Cytogenetic Map22q12.1UniSTS
Cytogenetic Map7p14.3UniSTS
Cytogenetic Map20q13.33UniSTS
Cytogenetic Map1p36.21UniSTS
TNG Radiation Hybrid Map41213.0UniSTS
D7S3207  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map19q13.43UniSTS
Cytogenetic Map7q36UniSTS
Cytogenetic Map5q14.1UniSTS
Cytogenetic Map8p11UniSTS
Cytogenetic Map2q31.1UniSTS
Cytogenetic Map8p21UniSTS
Cytogenetic Map13q12.11UniSTS
Cytogenetic Map7q36.1UniSTS
Cytogenetic Map16q22.1UniSTS
Cytogenetic Map7p11.2UniSTS
Cytogenetic Map9q33.2UniSTS
Cytogenetic Map1q42.12UniSTS
Cytogenetic Map4p13UniSTS
Cytogenetic Map3p21.1-p14.2UniSTS
Cytogenetic Map5q32UniSTS
Cytogenetic Map14q21UniSTS
Cytogenetic Map19q13.12UniSTS
Cytogenetic Map15q14-q15UniSTS
Cytogenetic Map2p24.2UniSTS
Cytogenetic Map7p15.3UniSTS
Cytogenetic Map4q13.3UniSTS
Cytogenetic Map10p12.31UniSTS
Cytogenetic Map6p12.3UniSTS
Cytogenetic Map2p23.3UniSTS
Cytogenetic Map20q11.23UniSTS
Cytogenetic MapXp22.2UniSTS
Cytogenetic Map19q13.3UniSTS
Cytogenetic Map7q21.2UniSTS
Cytogenetic Map19q13.11UniSTS
Cytogenetic Map19q13.41UniSTS
Cytogenetic Map20q13.31UniSTS
Cytogenetic Map18q11.1UniSTS
Cytogenetic Map17p13.3UniSTS
Cytogenetic Map19q13.33UniSTS
Cytogenetic Map16q21UniSTS
Cytogenetic Map1q32.1UniSTS
Cytogenetic Map16p12.2UniSTS
Cytogenetic Map2q31.2-q33.1UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 65 12 507 12 381 14 214 23 474 31 164 561 7
Low 2364 2579 1163 556 1206 395 4106 2111 3190 383 1286 1047 168 1 1204 2755 5 2
Below cutoff 6 400 56 56 356 56 36 63 70 5 7 1 33

Sequence


Reference Sequences
RefSeq Acc Id: ENST00000282296   ⟹   ENSP00000282296
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1957,681,977 - 57,690,648 (+)Ensembl
RefSeq Acc Id: ENST00000596085   ⟹   ENSP00000472230
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1957,682,035 - 57,717,301 (+)Ensembl
RefSeq Acc Id: ENST00000599402
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1957,682,007 - 57,686,835 (+)Ensembl
RefSeq Acc Id: ENST00000601064   ⟹   ENSP00000472674
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1957,681,969 - 57,688,028 (+)Ensembl
RefSeq Acc Id: NM_001270938   ⟹   NP_001257867
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381957,681,977 - 57,690,648 (+)NCBI
GRCh371958,193,337 - 58,201,179 (+)NCBI
HuRef1954,505,720 - 54,513,562 (+)NCBI
CHM1_11958,187,212 - 58,195,054 (+)NCBI
T2T-CHM13v2.01960,778,907 - 60,787,580 (+)NCBI
Sequence:
RefSeq Acc Id: NM_138347   ⟹   NP_612356
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381957,681,977 - 57,690,648 (+)NCBI
GRCh371958,193,337 - 58,201,179 (+)NCBI
Build 361962,885,217 - 62,892,991 (+)NCBI Archive
Celera1955,236,894 - 55,244,716 (+)RGD
HuRef1954,505,720 - 54,513,562 (+)NCBI
CHM1_11958,187,212 - 58,195,054 (+)NCBI
T2T-CHM13v2.01960,778,907 - 60,787,580 (+)NCBI
Sequence:
RefSeq Acc Id: NR_073102
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381957,681,977 - 57,690,648 (+)NCBI
GRCh371958,193,337 - 58,201,179 (+)NCBI
HuRef1954,505,720 - 54,513,562 (+)NCBI
CHM1_11958,187,212 - 58,195,054 (+)NCBI
T2T-CHM13v2.01960,778,907 - 60,787,580 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_612356   ⟸   NM_138347
- Peptide Label: isoform 1
- UniProtKB: Q8N246 (UniProtKB/Swiss-Prot),   P17034 (UniProtKB/Swiss-Prot),   B4DU22 (UniProtKB/Swiss-Prot),   Q9BRY1 (UniProtKB/Swiss-Prot),   Q7Z340 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001257867   ⟸   NM_001270938
- Peptide Label: isoform 2
- UniProtKB: Q7Z340 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSP00000472230   ⟸   ENST00000596085
RefSeq Acc Id: ENSP00000282296   ⟸   ENST00000282296
RefSeq Acc Id: ENSP00000472674   ⟸   ENST00000601064
Protein Domains
C2H2-type   KRAB

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q7Z340-F1-model_v2 AlphaFold Q7Z340 1-670 view protein structure

Promoters
RGD ID:13205919
Promoter ID:EPDNEW_H26540
Type:initiation region
Name:ZNF551_1
Description:zinc finger protein 551
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H26542  EPDNEW_H26543  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381957,681,977 - 57,682,037EPDNEW
RGD ID:13205923
Promoter ID:EPDNEW_H26542
Type:initiation region
Name:ZNF551_2
Description:zinc finger protein 551
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H26540  EPDNEW_H26543  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381957,682,007 - 57,682,067EPDNEW
RGD ID:13205925
Promoter ID:EPDNEW_H26543
Type:initiation region
Name:ZNF551_3
Description:zinc finger protein 551
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H26540  EPDNEW_H26542  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381957,682,183 - 57,682,243EPDNEW
RGD ID:6796377
Promoter ID:HG_KWN:31181
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:ENST00000359821,   NM_138347,   UC002QPV.2,   UC002QPX.2
Position:
Human AssemblyChrPosition (strand)Source
Build 361962,884,994 - 62,885,494 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:25108 AgrOrtholog
COSMIC ZNF551 COSMIC
Ensembl Genes ENSG00000204519 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000282296 ENTREZGENE
  ENST00000282296.10 UniProtKB/Swiss-Prot
  ENST00000596085.1 UniProtKB/TrEMBL
  ENST00000601064 ENTREZGENE
  ENST00000601064.1 UniProtKB/TrEMBL
Gene3D-CATH 6.10.140.140 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Classic Zinc Finger UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000204519 GTEx
HGNC ID HGNC:25108 ENTREZGENE
Human Proteome Map ZNF551 Human Proteome Map
InterPro KRAB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  KRAB_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_C2H2_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_C2H2_type UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:90233 UniProtKB/Swiss-Prot
NCBI Gene 90233 ENTREZGENE
PANTHER IP01015P-RELATED UniProtKB/TrEMBL
  KRAB DOMAIN C2H2 ZINC FINGER UniProtKB/TrEMBL
  ZINC FINGER PROTEIN UniProtKB/Swiss-Prot
  ZINC FINGER PROTEIN 471 UniProtKB/TrEMBL
  ZINC FINGER PROTEIN 551 UniProtKB/Swiss-Prot
  ZINC FINGER PROTEIN 747 UniProtKB/TrEMBL
Pfam KRAB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  zf-C2H2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA134993781 PharmGKB
PROSITE KRAB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART KRAB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZnF_C2H2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF109640 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF57667 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt B4DU22 ENTREZGENE
  M0R209_HUMAN UniProtKB/TrEMBL
  M0R2M4_HUMAN UniProtKB/TrEMBL
  P17034 ENTREZGENE
  Q7Z340 ENTREZGENE
  Q8N246 ENTREZGENE
  Q9BRY1 ENTREZGENE
  ZN551_HUMAN UniProtKB/Swiss-Prot
UniProt Secondary B4DU22 UniProtKB/Swiss-Prot
  P17034 UniProtKB/Swiss-Prot
  Q8N246 UniProtKB/Swiss-Prot
  Q9BRY1 UniProtKB/Swiss-Prot