NBN (nibrin) - Rat Genome Database

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Gene: NBN (nibrin) Homo sapiens
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Symbol: NBN
Name: nibrin
RGD ID: 1348611
HGNC Page HGNC
Description: Exhibits protein N-terminus binding activity and transcription factor binding activity. Involved in several processes, including DNA metabolic process; positive regulation of phosphorylation; and regulation of telomere maintenance. Localizes to chromosome and nucleus. Implicated in several diseases, including Nijmegen breakage syndrome; acute lymphoblastic leukemia; aplastic anemia; breast cancer; and reproductive organ cancer (multiple). Biomarker of Alzheimer's disease and breast cancer.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AT-V1; AT-V2; ATV; cell cycle regulatory protein p95; FLJ10155; MGC87362; NBS; NBS1; Nijmegen breakage syndrome 1 (nibrin); nijmegen breakage syndrome protein 1; P95; p95 protein of the MRE11/RAD50 complex
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl889,933,331 - 90,003,228 (-)EnsemblGRCh38hg38GRCh38
GRCh38.p13 Ensembl889,933,336 - 90,003,228 (-)EnsemblGRCh38hg38GRCh38
GRCh38889,933,331 - 89,984,698 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37890,945,559 - 90,996,895 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36891,014,740 - 91,066,075 (-)NCBINCBI36hg18NCBI36
Build 34891,014,888 - 91,066,072NCBI
Celera887,140,375 - 87,191,710 (-)NCBI
Cytogenetic Map8q21.3NCBI
HuRef886,155,741 - 86,207,078 (-)NCBIHuRef
CHM1_1890,986,489 - 91,037,878 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model