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Gene: PLEKHA8 (pleckstrin homology domain containing A8) Homo sapiens
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Symbol: PLEKHA8
Name: pleckstrin homology domain containing A8
Description: Exhibits several functions, including ceramide binding activity; glycolipid transfer activity; and phosphatidylinositol-4-phosphate binding activity. Involved in ER to Golgi ceramide transport. Localizes to the nucleoplasm and trans-Golgi network; INTERACTS WITH 2-hydroxypropanoic acid; arsane; arsenic atom.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: DKFZp313M1034; DKFZp686J09164; FAPP-2; FAPP2; hFAPP2; MGC3358; PH domain-containing family A member 8; phosphatidylinositol 4-phosphate adaptor protein-2; phosphatidylinositol-four-phosphate adapter protein 2; phosphoinositol 4-phosphate adapter protein 2; phosphoinositol 4-phosphate adaptor protein-2; pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8; pleckstrin homology domain-containing family A member 8; serologically defined breast cancer antigen NY-BR-86
Orthologs:
Related Pseudogenes: PLEKHA8P1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl730,027,404 - 30,130,483 (+)Ensembl
GRCh38730,028,361 - 30,130,483 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37730,067,977 - 30,157,961 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36730,034,813 - 30,096,885 (+)NCBINCBI36hg18NCBI36
Build 34729,841,527 - 29,903,597NCBI
Celera730,057,679 - 30,119,744 (+)NCBI
Cytogenetic Map7p14.3NCBI
HuRef729,949,816 - 30,040,209 (+)NCBIHuRef
CHM1_1730,068,087 - 30,158,038 (+)NCBICHM1_1
CRA_TCAGchr7v2730,117,806 - 30,207,752 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on PLEKHA8
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1348276
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.