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Gene: EDA (ectodysplasin A) Homo sapiens
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Symbol: EDA
Name: ectodysplasin A
Description: Exhibits death receptor agonist activity and death receptor binding activity. Involved in several processes, including odontogenesis of dentin-containing tooth; positive regulation of NF-kappaB transcription factor activity; and regulation of NIK/NF-kappaB signaling. Localizes to the intracellular membrane-bounded organelle and lipid droplet. Implicated in ectodermal dysplasia and tooth agenesis.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ECTD1; ectodermal dysplasia protein; ectodysplasin-A; ED1; ED1-A1; ED1-A2; EDA-A1; EDA-A2; EDA1; EDA2; HED; HED1; ODT1; oligodontia 1; STHAGX1; TNLG7C; tumor necrosis factor ligand 7C; X-linked anhidroitic ectodermal dysplasia protein; XHED; XLHED
Orthologs:
Mus musculus (house mouse) : Eda (ectodysplasin-A)  MGI  Alliance
Rattus norvegicus (Norway rat) : Eda (ectodysplasin-A)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Eda (ectodysplasin A)
Pan paniscus (bonobo/pygmy chimpanzee) : EDA (ectodysplasin A)
Canis lupus familiaris (dog) : EDA (ectodysplasin A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC101956136 (ectodysplasin-A)
Sus scrofa (pig) : EDA (ectodysplasin A)
Chlorocebus sabaeus (African green monkey) : EDA (ectodysplasin A)
Heterocephalus glaber (naked mole-rat) : Eda (ectodysplasin A)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 EnsemblX69,616,067 - 70,039,472 (+)Ensembl
GRCh38X69,616,086 - 70,039,472 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X68,835,911 - 69,259,322 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X68,752,636 - 69,176,047 (+)NCBINCBI36hg18NCBI36
Build 34X68,618,931 - 69,042,340NCBI
CeleraX69,189,229 - 69,612,705 (+)NCBI
Cytogenetic MapXq13.1NCBI
HuRefX62,655,756 - 63,080,124 (+)NCBIHuRef
CHM1_1X68,729,282 - 69,152,930 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


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References - uncurated

Genomics

Comparative Map Data
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miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
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Additional Information

External Database Links
Nomenclature History
 
More on EDA
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1348155
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-12-31
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.