Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: MACROD2 (mono-ADP ribosylhydrolase 2) Homo sapiens
Symbol: MACROD2
Name: mono-ADP ribosylhydrolase 2
Description: Exhibits ADP-ribosylglutamate hydrolase activity and deacetylase activity. Involved in cellular response to DNA damage stimulus; peptidyl-glutamate ADP-deribosylation; and purine nucleoside metabolic process. Localizes to nucleolus and nucleoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: [Protein ADP-ribosylaspartate] hydrolase MACROD2; [Protein ADP-ribosylglutamate] hydrolase; [Protein ADP-ribosylglutamate] hydrolase MACROD2; ADP-ribose glycohydrolase MACROD2; C20orf133; C2orf133; dJ631M13.5; MACRO domain containing 2; MACRO domain-containing protein 2; O-acetyl-ADP-ribose deacetylase; O-acetyl-ADP-ribose deacetylase MACROD2; RP11-189J1.1
Mus musculus (house mouse) : Macrod2 (mono-ADP ribosylhydrolase 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Macrod2 (mono-ADP ribosylhydrolase 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Macrod2 (mono-ADP ribosylhydrolase 2)
Canis lupus familiaris (dog) : MACROD2 (mono-ADP ribosylhydrolase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Macrod2 (mono-ADP ribosylhydrolase 2)
Sus scrofa (pig) : MACROD2 (mono-ADP ribosylhydrolase 2)
Chlorocebus sabaeus (African green monkey) : MACROD2 (mono-ADP ribosylhydrolase 2)
Heterocephalus glaber (naked mole-rat) : Macrod2 (mono-ADP ribosylhydrolase 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl2013,995,369 - 16,053,197 (+)EnsemblGRCh38hg38GRCh38
GRCh382013,995,516 - 16,053,197 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372013,976,146 - 16,033,842 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362013,924,146 - 15,981,842 (+)NCBINCBI36hg18NCBI36
Build 342013,924,318 - 13,982,313NCBI
Celera2014,051,522 - 16,108,818 (+)NCBI
Cytogenetic Map20p12.1NCBI
HuRef2013,936,352 - 15,994,332 (+)NCBIHuRef
CHM1_12013,976,154 - 16,033,759 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on MACROD2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1347920
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-05-05
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.