STARD3 (StAR related lipid transfer domain containing 3) - Rat Genome Database

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Gene: STARD3 (StAR related lipid transfer domain containing 3) Homo sapiens
Analyze
Symbol: STARD3
Name: StAR related lipid transfer domain containing 3
RGD ID: 1347857
HGNC Page HGNC
Description: Enables cholesterol binding activity and protein homodimerization activity. Involved in cholesterol transport and vesicle tethering to endoplasmic reticulum. Located in endoplasmic reticulum-endosome membrane contact site; late endosome membrane; and nucleoplasm. Colocalizes with endoplasmic reticulum membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CAB1; es64; FLJ41370; metastatic lymph node gene 64 protein; metastatic lymph node protein 64; MLN 64; MLN64; StAR-related lipid transfer (START) domain containing 3; StAR-related lipid transfer domain containing 3; stAR-related lipid transfer protein 3; START domain-containing protein 3; steroidogenic acute regulatory protein related
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1739,637,090 - 39,664,201 (+)EnsemblGRCh38hg38GRCh38
GRCh381739,637,144 - 39,664,201 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371737,793,397 - 37,820,454 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361735,046,938 - 35,073,263 (+)NCBINCBI36hg18NCBI36
Build 341735,046,937 - 35,073,248NCBI
Celera1734,453,066 - 34,480,183 (+)NCBI
Cytogenetic Map17q12NCBI
HuRef1733,587,056 - 33,614,385 (+)NCBIHuRef
CHM1_11738,029,159 - 38,056,275 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:7490069   PMID:8125298   PMID:9139840   PMID:9237999   PMID:9270027   PMID:10802740   PMID:10995240   PMID:11053434   PMID:11196440   PMID:12011452   PMID:12011453   PMID:12070139  
PMID:12398991   PMID:12459035   PMID:12477932   PMID:14702039   PMID:14715710   PMID:15010812   PMID:15489334   PMID:15718238   PMID:15930133   PMID:16709157   PMID:16990645   PMID:17117180  
PMID:17897319   PMID:18331352   PMID:19124506   PMID:19272380   PMID:19913121   PMID:19965586   PMID:20198306   PMID:20628086   PMID:20686565   PMID:21322544   PMID:21516116   PMID:24097068  
PMID:24105263   PMID:24276243   PMID:24291029   PMID:24623722   PMID:25416956   PMID:25459514   PMID:25681734   PMID:26186194   PMID:27055092   PMID:27068960   PMID:27487925   PMID:28282615  
PMID:28377464   PMID:28514442   PMID:29117863   PMID:29513927   PMID:29858488   PMID:31741433   PMID:32296183   PMID:33144569   PMID:34079125  


Genomics

Comparative Map Data
STARD3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1739,637,090 - 39,664,201 (+)EnsemblGRCh38hg38GRCh38
GRCh381739,637,144 - 39,664,201 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371737,793,397 - 37,820,454 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361735,046,938 - 35,073,263 (+)NCBINCBI36hg18NCBI36
Build 341735,046,937 - 35,073,248NCBI
Celera1734,453,066 - 34,480,183 (+)NCBI
Cytogenetic Map17q12NCBI
HuRef1733,587,056 - 33,614,385 (+)NCBIHuRef
CHM1_11738,029,159 - 38,056,275 (+)NCBICHM1_1
Stard3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391198,249,193 - 98,271,938 (+)NCBIGRCm39mm39
GRCm39 Ensembl1198,249,194 - 98,271,938 (+)Ensembl
GRCm381198,358,367 - 98,381,112 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1198,358,368 - 98,381,112 (+)EnsemblGRCm38mm10GRCm38
MGSCv371198,219,698 - 98,242,413 (+)NCBIGRCm37mm9NCBIm37
MGSCv361198,174,474 - 98,197,189 (+)NCBImm8
Celera11108,012,664 - 108,035,326 (+)NCBICelera
Cytogenetic Map11DNCBI
Stard3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21083,357,329 - 83,379,873 (+)NCBImRatBN7.2
Rnor_6.0 Ensembl1086,313,383 - 86,335,923 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01086,313,430 - 86,335,868 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01086,110,514 - 86,133,026 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41087,132,237 - 87,160,076 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1082,104,819 - 82,127,138 (+)NCBICelera
Cytogenetic Map10q31NCBI
Stard3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545114,394,466 - 14,413,810 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495545114,395,088 - 14,412,041 (+)NCBIChiLan1.0ChiLan1.0
STARD3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11717,841,500 - 17,868,535 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1717,842,217 - 17,868,535 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01717,625,390 - 17,651,765 (-)NCBIMhudiblu_PPA_v0panPan3
STARD3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1922,814,782 - 22,837,525 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl922,814,460 - 22,837,426 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha922,287,263 - 22,309,962 (-)NCBI
ROS_Cfam_1.0923,608,455 - 23,631,214 (-)NCBI
UMICH_Zoey_3.1922,381,099 - 22,403,791 (-)NCBI
UNSW_CanFamBas_1.0922,642,097 - 22,664,836 (-)NCBI
UU_Cfam_GSD_1.0922,767,204 - 22,789,919 (-)NCBI
Stard3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560222,220,392 - 22,243,068 (-)NCBI
SpeTri2.0NW_00493649014,832,067 - 14,856,330 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
STARD3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1222,653,032 - 22,688,597 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11222,654,920 - 22,680,803 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21223,079,502 - 23,105,357 (+)NCBISscrofa10.2Sscrofa10.2susScr3
STARD3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11666,503,544 - 66,530,214 (-)NCBI
ChlSab1.1 Ensembl1666,504,119 - 66,513,861 (-)Ensembl
Vero_WHO_p1.0NW_02366607737,415,108 - 37,441,767 (-)NCBI
Stard3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247953,414,431 - 3,431,994 (-)NCBI

Position Markers
WI-19537  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371737,792,592 - 37,792,864UniSTSGRCh37
Build 361735,046,118 - 35,046,390RGDNCBI36
Celera1734,452,325 - 34,452,597RGD
Cytogenetic Map17q11-q12UniSTS
Cytogenetic Map17q12UniSTS
HuRef1733,586,315 - 33,586,587UniSTS
GeneMap99-GB4 RH Map17304.32UniSTS
Whitehead-RH Map17338.1UniSTS
NCBI RH Map17445.6UniSTS
RH66410  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371737,792,603 - 37,792,723UniSTSGRCh37
Build 361735,046,129 - 35,046,249RGDNCBI36
Celera1734,452,336 - 34,452,456RGD
Cytogenetic Map17q11-q12UniSTS
Cytogenetic Map17q12UniSTS
HuRef1733,586,326 - 33,586,446UniSTS
RH91094  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371737,819,528 - 37,819,701UniSTSGRCh37
Build 361735,073,054 - 35,073,227RGDNCBI36
Celera1734,479,257 - 34,479,430RGD
Cytogenetic Map17q11-q12UniSTS
HuRef1733,613,248 - 33,613,421UniSTS
GeneMap99-GB4 RH Map17307.34UniSTS
SHGC-31632  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371737,819,203 - 37,819,426UniSTSGRCh37
Build 361735,072,729 - 35,072,952RGDNCBI36
Celera1734,478,932 - 34,479,155RGD
Cytogenetic Map17q11-q12UniSTS
HuRef1733,612,923 - 33,613,146UniSTS
PPP1R1B_4142  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371737,792,240 - 37,792,890UniSTSGRCh37
Build 361735,045,766 - 35,046,416RGDNCBI36
Celera1734,451,973 - 34,452,623RGD
HuRef1733,585,963 - 33,586,613UniSTS

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:9950
Count of miRNA genes:1123
Interacting mature miRNAs:1456
Transcripts:ENST00000336308, ENST00000394250, ENST00000443521, ENST00000460894, ENST00000471896, ENST00000481171, ENST00000484773, ENST00000488876, ENST00000544210, ENST00000577248, ENST00000578232, ENST00000578254, ENST00000578384, ENST00000578577, ENST00000578686, ENST00000579479, ENST00000580331, ENST00000580551, ENST00000580611, ENST00000581894, ENST00000582874, ENST00000583419, ENST00000583582, ENST00000583639, ENST00000583718, ENST00000583884, ENST00000584850, ENST00000585214, ENST00000585269
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High 1 1 1
Medium 2422 2675 1653 554 1914 397 4227 1823 3545 360 1439 1605 171 1204 2661 3
Low 11 311 71 70 33 67 129 371 187 58 17 3 3 1 127 1 2
Below cutoff 2 1 1 1 1 3 1 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001165937 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001165938 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_006804 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017024041 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_024450549 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB209772 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC087491 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK123364 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK225069 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK300176 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK300842 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK301524 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK303114 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL831952 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC008356 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC008747 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC019286 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC025679 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC047766 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BT006964 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471152 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D38255 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DC367486 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X80198 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000336308   ⟹   ENSP00000337446
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1739,637,144 - 39,664,201 (+)Ensembl
RefSeq Acc Id: ENST00000394250   ⟹   ENSP00000377794
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1739,637,144 - 39,663,434 (+)Ensembl
RefSeq Acc Id: ENST00000443521   ⟹   ENSP00000411710
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1739,653,125 - 39,658,762 (+)Ensembl
RefSeq Acc Id: ENST00000460894
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1739,653,500 - 39,658,001 (+)Ensembl
RefSeq Acc Id: ENST00000471896
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1739,658,989 - 39,663,469 (+)Ensembl
RefSeq Acc Id: ENST00000481171
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1739,657,911 - 39,663,484 (+)Ensembl
RefSeq Acc Id: ENST00000484773
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1739,653,049 - 39,658,693 (+)Ensembl
RefSeq Acc Id: ENST00000488876
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1739,653,098 - 39,663,484 (+)Ensembl
RefSeq Acc Id: ENST00000544210   ⟹   ENSP00000439869
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1739,637,141 - 39,663,094 (+)Ensembl
RefSeq Acc Id: ENST00000577248   ⟹   ENSP00000463460
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1739,637,147 - 39,658,458 (+)Ensembl
RefSeq Acc Id: ENST00000578232
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1739,637,090 - 39,659,553 (+)Ensembl
RefSeq Acc Id: ENST00000578254
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1739,637,140 - 39,657,798 (+)Ensembl
RefSeq Acc Id: ENST00000578384
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1739,660,220 - 39,662,479 (+)Ensembl
RefSeq Acc Id: ENST00000578577   ⟹   ENSP00000464472
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1739,637,142 - 39,663,007 (+)Ensembl
RefSeq Acc Id: ENST00000578686
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1739,660,286 - 39,661,321 (+)Ensembl
RefSeq Acc Id: ENST00000579479   ⟹   ENSP00000462483
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1739,637,147 - 39,657,810 (+)Ensembl
RefSeq Acc Id: ENST00000580331   ⟹   ENSP00000462541
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1739,652,489 - 39,657,052 (+)Ensembl
RefSeq Acc Id: ENST00000580551
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1739,637,139 - 39,657,887 (+)Ensembl
RefSeq Acc Id: ENST00000580611   ⟹   ENSP00000463613
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1739,637,153 - 39,663,484 (+)Ensembl
RefSeq Acc Id: ENST00000581894   ⟹   ENSP00000462859
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1739,637,142 - 39,657,833 (+)Ensembl
RefSeq Acc Id: ENST00000582874
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1739,653,535 - 39,658,776 (+)Ensembl
RefSeq Acc Id: ENST00000583419   ⟹   ENSP00000463681
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1739,652,778 - 39,658,460 (+)Ensembl
RefSeq Acc Id: ENST00000583582
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1739,637,142 - 39,658,819 (+)Ensembl
RefSeq Acc Id: ENST00000583639
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1739,660,196 - 39,662,896 (+)Ensembl
RefSeq Acc Id: ENST00000583718   ⟹   ENSP00000464204
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1739,637,370 - 39,657,830 (+)Ensembl
RefSeq Acc Id: ENST00000583884   ⟹   ENSP00000464288
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1739,659,064 - 39,662,321 (+)Ensembl
RefSeq Acc Id: ENST00000584850
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1739,658,446 - 39,663,469 (+)Ensembl
RefSeq Acc Id: ENST00000585214
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1739,637,162 - 39,658,296 (+)Ensembl
RefSeq Acc Id: ENST00000585269
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1739,658,394 - 39,663,433 (+)Ensembl
RefSeq Acc Id: NM_001165937   ⟹   NP_001159409
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381739,637,144 - 39,664,201 (+)NCBI
GRCh371737,793,333 - 37,820,454 (+)NCBI
HuRef1733,587,056 - 33,614,385 (+)ENTREZGENE
CHM1_11738,029,159 - 38,056,275 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001165938   ⟹   NP_001159410
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381739,637,144 - 39,664,201 (+)NCBI
GRCh371737,793,333 - 37,820,454 (+)NCBI
HuRef1733,587,056 - 33,614,385 (+)ENTREZGENE
CHM1_11738,029,159 - 38,056,275 (+)NCBI
Sequence:
RefSeq Acc Id: NM_006804   ⟹   NP_006795
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381739,637,144 - 39,664,201 (+)NCBI
GRCh371737,793,333 - 37,820,454 (+)ENTREZGENE
GRCh371737,793,333 - 37,820,454 (+)NCBI
Build 361735,046,938 - 35,073,263 (+)NCBI Archive
HuRef1733,587,056 - 33,614,385 (+)ENTREZGENE
CHM1_11738,029,159 - 38,056,275 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017024041   ⟹   XP_016879530
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381739,653,052 - 39,664,201 (+)NCBI
Sequence:
RefSeq Acc Id: XM_024450549   ⟹   XP_024306317
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381739,653,734 - 39,664,201 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_006795   ⟸   NM_006804
- Peptide Label: isoform 1
- UniProtKB: Q14849 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001159410   ⟸   NM_001165938
- Peptide Label: isoform 3
- UniProtKB: Q14849 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001159409   ⟸   NM_001165937
- Peptide Label: isoform 2
- UniProtKB: Q14849 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_016879530   ⟸   XM_017024041
- Peptide Label: isoform X1
- UniProtKB: Q14849 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_024306317   ⟸   XM_024450549
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSP00000463613   ⟸   ENST00000580611
RefSeq Acc Id: ENSP00000462541   ⟸   ENST00000580331
RefSeq Acc Id: ENSP00000462859   ⟸   ENST00000581894
RefSeq Acc Id: ENSP00000463681   ⟸   ENST00000583419
RefSeq Acc Id: ENSP00000439869   ⟸   ENST00000544210
RefSeq Acc Id: ENSP00000464288   ⟸   ENST00000583884
RefSeq Acc Id: ENSP00000464204   ⟸   ENST00000583718
RefSeq Acc Id: ENSP00000337446   ⟸   ENST00000336308
RefSeq Acc Id: ENSP00000411710   ⟸   ENST00000443521
RefSeq Acc Id: ENSP00000463460   ⟸   ENST00000577248
RefSeq Acc Id: ENSP00000464472   ⟸   ENST00000578577
RefSeq Acc Id: ENSP00000462483   ⟸   ENST00000579479
RefSeq Acc Id: ENSP00000377794   ⟸   ENST00000394250
Protein Domains
MENTAL   START

Promoters
RGD ID:6794588
Promoter ID:HG_KWN:25995
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:NM_001165937,   NM_001165938,   OTTHUMT00000256933
Position:
Human AssemblyChrPosition (strand)Source
Build 361735,046,696 - 35,047,196 (+)MPROMDB
RGD ID:7234847
Promoter ID:EPDNEW_H23169
Type:initiation region
Name:STARD3_1
Description:StAR related lipid transfer domain containing 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H23170  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381739,637,147 - 39,637,207EPDNEW
RGD ID:7234849
Promoter ID:EPDNEW_H23170
Type:multiple initiation site
Name:STARD3_2
Description:StAR related lipid transfer domain containing 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H23169  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381739,642,738 - 39,642,798EPDNEW

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 17q21.33-24.2(chr17:36449220-68170214)x3 copy number gain See cases [RCV000050957] Chr17:36449220..68170214 [GRCh38]
Chr17:48563237..65936105 [GRCh37]
Chr17:45918236..63677950 [NCBI36]
Chr17:17q21.33-24.2
pathogenic
GRCh38/hg38 17q23.2-25.3(chr17:36449220-83086677)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052483]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052483]|See cases [RCV000052483] Chr17:36449220..83086677 [GRCh38]
Chr17:58617905..81044553 [GRCh37]
Chr17:55972687..78637842 [NCBI36]
Chr17:17q23.2-25.3
pathogenic
GRCh38/hg38 17q12-21.31(chr17:39199873-45629579)x3 copy number gain See cases [RCV000052479] Chr17:39199873..45629579 [GRCh38]
Chr17:37356126..43706945 [GRCh37]
Chr17:34609652..41062728 [NCBI36]
Chr17:17q12-21.31
pathogenic
NM_001165937.1(STARD3):c.869C>T (p.Pro290Leu) single nucleotide variant Malignant melanoma [RCV000071437] Chr17:39660441 [GRCh38]
Chr17:37816694 [GRCh37]
Chr17:35070220 [NCBI36]
Chr17:17q12
not provided
GRCh38/hg38 17q23.1-25.1(chr17:36449220-75053130)x3 copy number gain See cases [RCV000137437] Chr17:36449220..75053130 [GRCh38]
Chr17:57595736..73049225 [GRCh37]
Chr17:54950518..70560820 [NCBI36]
Chr17:17q23.1-25.1
pathogenic
GRCh38/hg38 17q12(chr17:39036037-39694679)x3 copy number gain See cases [RCV000140753] Chr17:39036037..39694679 [GRCh38]
Chr17:37192290..37850932 [GRCh37]
Chr17:34445816..35104458 [NCBI36]
Chr17:17q12
likely benign|uncertain significance
GRCh37/hg19 17p13.3-q25.3(chr17:526-81041938) copy number gain See cases [RCV000511439] Chr17:526..81041938 [GRCh37]
Chr17:17p13.3-q25.3
pathogenic
GRCh37/hg19 17q12(chr17:37313691-37868516)x3 copy number gain See cases [RCV000512247] Chr17:37313691..37868516 [GRCh37]
Chr17:17q12
uncertain significance
GRCh37/hg19 17p13.3-q25.3(chr17:526-81041938)x3 copy number gain See cases [RCV000512441] Chr17:526..81041938 [GRCh37]
Chr17:17p13.3-q25.3
pathogenic
GRCh37/hg19 17q12(chr17:36972794-38033708)x4 copy number gain not provided [RCV000683933] Chr17:36972794..38033708 [GRCh37]
Chr17:17q12
uncertain significance
GRCh37/hg19 17p13.3-q25.3(chr17:8547-81060040)x3 copy number gain not provided [RCV000739324] Chr17:8547..81060040 [GRCh37]
Chr17:17p13.3-q25.3
pathogenic
GRCh37/hg19 17p13.3-q25.3(chr17:7214-81058310)x3 copy number gain not provided [RCV000739320] Chr17:7214..81058310 [GRCh37]
Chr17:17p13.3-q25.3
pathogenic
GRCh37/hg19 17p13.3-q25.3(chr17:12344-81057996)x3 copy number gain not provided [RCV000739325] Chr17:12344..81057996 [GRCh37]
Chr17:17p13.3-q25.3
pathogenic
GRCh37/hg19 17q12(chr17:37387413-37879941)x3 copy number gain not provided [RCV000739510] Chr17:37387413..37879941 [GRCh37]
Chr17:17q12
benign
GRCh37/hg19 17q12(chr17:37818561-37822416)x1 copy number loss not provided [RCV000752030] Chr17:37818561..37822416 [GRCh37]
Chr17:17q12
benign
GRCh37/hg19 17p11.2-q21.2(chr17:21690653-38772647)x3 copy number gain not provided [RCV000846852] Chr17:21690653..38772647 [GRCh37]
Chr17:17p11.2-q21.2
pathogenic
GRCh37/hg19 17q12(chr17:37190609-37868002)x3 copy number gain not provided [RCV000849616] Chr17:37190609..37868002 [GRCh37]
Chr17:17q12
uncertain significance

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:17579 AgrOrtholog
COSMIC STARD3 COSMIC
Ensembl Genes ENSG00000131748 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSP00000337446 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000377794 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000411710 UniProtKB/TrEMBL
  ENSP00000439869 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000462483 UniProtKB/TrEMBL
  ENSP00000462541 UniProtKB/TrEMBL
  ENSP00000462859 UniProtKB/TrEMBL
  ENSP00000463460 UniProtKB/TrEMBL
  ENSP00000463613 UniProtKB/TrEMBL
  ENSP00000463681 UniProtKB/TrEMBL
  ENSP00000464204 UniProtKB/TrEMBL
  ENSP00000464288 UniProtKB/TrEMBL
  ENSP00000464472 UniProtKB/TrEMBL
Ensembl Transcript ENST00000336308 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000394250 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000443521 UniProtKB/TrEMBL
  ENST00000544210 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000577248 UniProtKB/TrEMBL
  ENST00000578577 UniProtKB/TrEMBL
  ENST00000579479 UniProtKB/TrEMBL
  ENST00000580331 UniProtKB/TrEMBL
  ENST00000580611 UniProtKB/TrEMBL
  ENST00000581894 UniProtKB/TrEMBL
  ENST00000583419 UniProtKB/TrEMBL
  ENST00000583718 UniProtKB/TrEMBL
  ENST00000583884 UniProtKB/TrEMBL
Gene3D-CATH 3.30.530.20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000131748 GTEx
HGNC ID HGNC:17579 ENTREZGENE
Human Proteome Map STARD3 Human Proteome Map
InterPro MENTAL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  StAR-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  STARD3_MLN64_C UniProtKB/Swiss-Prot
  START-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  START_lipid-bd_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:10948 UniProtKB/Swiss-Prot
NCBI Gene 10948 ENTREZGENE
OMIM 607048 OMIM
Pfam MENTAL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  START UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA134981867 PharmGKB
PRINTS STARPROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE MENTAL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  START UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART START UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt C9J555_HUMAN UniProtKB/TrEMBL
  J3KSH0_HUMAN UniProtKB/TrEMBL
  J3KSL3_HUMAN UniProtKB/TrEMBL
  J3KT87_HUMAN UniProtKB/TrEMBL
  J3QLA7_HUMAN UniProtKB/TrEMBL
  J3QLM1_HUMAN UniProtKB/TrEMBL
  J3QLS1_HUMAN UniProtKB/TrEMBL
  J3QRG8_HUMAN UniProtKB/TrEMBL
  J3QRM3_HUMAN UniProtKB/TrEMBL
  J3QS10_HUMAN UniProtKB/TrEMBL
  Q14849 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary A8MXA4 UniProtKB/Swiss-Prot
  B4DUY1 UniProtKB/Swiss-Prot
  F5H0G2 UniProtKB/Swiss-Prot
  Q53Y53 UniProtKB/Swiss-Prot
  Q96HM9 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-11-24 STARD3  StAR related lipid transfer domain containing 3    StAR-related lipid transfer domain containing 3  Symbol and/or name change 5135510 APPROVED
2015-11-10 STARD3  StAR-related lipid transfer domain containing 3    StAR-related lipid transfer (START) domain containing 3  Symbol and/or name change 5135510 APPROVED