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Gene: RAPGEFL1 (Rap guanine nucleotide exchange factor like 1) Homo sapiens
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Symbol: RAPGEFL1
Name: Rap guanine nucleotide exchange factor like 1
Description: Predicted to have guanyl-nucleotide exchange factor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and nervous system development. Predicted to localize to the membrane; INTERACTS WITH 17beta-estradiol; 5-aza-2'-deoxycytidine; atrazine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: link GEFII; Link guanine nucleotide exchange factor II; Link-GEFII; MGC134798; MGC134799; Rap guanine nucleotide exchange factor (GEF)-like 1; rap guanine nucleotide exchange factor-like 1; RAP guanine-nucleotide-exchange factor (GEF)-like 1
Orthologs:
Mus musculus (house mouse) : Rapgefl1 (Rap guanine nucleotide exchange factor (GEF)-like 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Rapgefl1 (Rap guanine nucleotide exchange factor like 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rapgefl1 (Rap guanine nucleotide exchange factor like 1)
Pan paniscus (bonobo/pygmy chimpanzee) : RAPGEFL1 (Rap guanine nucleotide exchange factor like 1)
Canis lupus familiaris (dog) : RAPGEFL1 (Rap guanine nucleotide exchange factor like 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rapgefl1 (Rap guanine nucleotide exchange factor like 1)
Sus scrofa (pig) : RAPGEFL1 (Rap guanine nucleotide exchange factor like 1)
Chlorocebus sabaeus (African green monkey) : RAPGEFL1 (Rap guanine nucleotide exchange factor like 1)
Heterocephalus glaber (naked mole-rat) : Rapgefl1 (Rap guanine nucleotide exchange factor like 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl1740,177,010 - 40,195,656 (+)EnsemblGRCh38hg38GRCh38
GRCh381740,177,010 - 40,195,656 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371738,334,242 - 38,351,906 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361735,591,394 - 35,605,426 (+)NCBINCBI36hg18NCBI36
Build 341735,588,138 - 35,605,426NCBI
Celera1734,994,758 - 35,012,421 (+)NCBI
Cytogenetic Map17q21.1NCBI
HuRef1734,127,434 - 34,145,100 (+)NCBIHuRef
CHM1_11738,568,948 - 38,587,594 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on RAPGEFL1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1347798
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.