MIR19B2 (microRNA 19b-2) - Rat Genome Database

Name: MIR19B2
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: MIR19B2 (microRNA 19b-2) Homo sapiens

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Symbol:

MIR19B2

Name:

microRNA 19b-2

RGD ID:

1347760

Description:

Predicted to be involved in several processes, including cellular response to leukemia inhibitory factor; long-term synaptic potentiation; and negative regulation of B cell apoptotic process. Predicted to localize to RISC complex.

Type:

ncrna

RefSeq Status:

PROVISIONAL

Also known as:

miR-19b-2; MIRN19B2

Orthologs:

Mus musculus (house mouse) : Mir19b-2 (microRNA 19b-2) MGI Alliance
Rattus norvegicus (Norway rat) : Mir19b2 (microRNA 19b-2) Alliance
Canis lupus familiaris (dog) : MIR19B-2 (microRNA mir-19b-2)
Sus scrofa (pig) : MIR19B-2 (microRNA mir-19b-2)

more info ...

Allele / Splice:

See ClinVar data

Latest Assembly:

GRCh38 - Human Genome Assembly GRCh38

Position:

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38.p13 Ensembl	X	134,169,671 - 134,169,766 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh38	X	134,169,671 - 134,169,766 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	X	133,303,701 - 133,303,796 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	X	133,131,366 - 133,131,461 (-)	NCBI	NCBI36		hg18	NCBI36
Celera	X	133,690,534 - 133,690,629 (-)	NCBI
Cytogenetic Map	X	q26.2	NCBI
HuRef	X	122,701,740 - 122,701,835 (-)	NCBI		HuRef
CHM1_1	X	133,215,397 - 133,215,492 (-)	NCBI		CHM1_1

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation (Toggle Annotation Detail/Summary View)

Disease Annotations

Gene-Chemical Interaction Annotations

Gene Ontology Annotations

References - curated

References - uncurated

Genomics

Comparative Map Data

miRNA Target Status

Confirmed Targets

Gene Target	Mature miRNA	Method Name	Result Type	Data Type	Support Type	PMID
DKK3	hsa-miR-19b-3p	OncomiRDB	external_info	NA	NA	21796614
MYCN	hsa-miR-19b-3p	OncomiRDB	external_info	NA	NA	21654684
SOCS1	hsa-miR-19b-3p	OncomiRDB	external_info	NA	NA	18728182
NR3C2	hsa-miR-19b-3p	Mirtarbase	external_info	Sequencing	Functional MTI (Weak)	20371350
BACE1	hsa-miR-19b-3p	Mirtarbase	external_info	Luciferase reporter assay//Reporter assay;Other	Non-Functional MTI	18434550
PTEN	hsa-miR-19b-3p	Mirtarbase	external_info	Luciferase reporter assay//qRT-PCR//Western blot	Functional MTI	20008935
ATXN1	hsa-miR-19b-3p	Mirtarbase	external_info	Luciferase reporter assay//qRT-PCR//Western blot	Functional MTI	18758459
HIPK3	hsa-miR-19b-3p	Mirtarbase	external_info	Luciferase reporter assay	Functional MTI	17575136
ARID4B	hsa-miR-19b-3p	Mirtarbase	external_info	Luciferase reporter assay	Non-Functional MTI	17575136
ESR1	hsa-miR-19b-3p	Mirtarbase	external_info	Western blot//qRT-PCR//Luciferase reporter assay	Functional MTI	19706389
NCOA3	hsa-miR-19b-3p	Mirtarbase	external_info	Western blot	Non-Functional MTI	19706389
KAT2B	hsa-miR-19b-3p	Mirtarbase	external_info	Western blot//Luciferase reporter assay	Non-Functional MTI	18728182
SOCS1	hsa-miR-19b-3p	Mirtarbase	external_info	Luciferase reporter assay//Western blot	Functional MTI	18728182
BCL2L11	hsa-miR-19b-3p	Mirtarbase	external_info	Luciferase reporter assay	Functional MTI	18728182
TGFBR2	hsa-miR-19b-3p	Mirtarbase	external_info	Microarray//qRT-PCR	Functional MTI (Weak)	19435428
BMPR2	hsa-miR-19b-3p	Mirtarbase	external_info	Luciferase reporter assay//qRT-PCR//Western blot	Non-Functional MTI	19390056
CUL5	hsa-miR-19b-3p	Mirtarbase	external_info	qRT-PCR//Western blot	Functional MTI	22561557
TLR2	hsa-miR-19b-3p	Mirtarbase	external_info	Luciferase reporter assay//qRT-PCR//Western blot	Functional MTI	22105995
CYP19A1	hsa-miR-19b-3p	Mirtarbase	external_info	Luciferase reporter assay	Functional MTI	23438603
MYCN	hsa-miR-19b-3p	Mirtarbase	external_info	Reporter assay	Functional MTI	21654684
DDX6	hsa-miR-19b-3p	Mirtarbase	external_info	CLASH	Functional MTI (Weak)	23622248
BACE1	hsa-miR-19b-3p	Tarbase	external_info	Reporter Gene	NEGATIVE
MYCN	hsa-miR-19b-3p	Tarbase	external_info	Reporter Gene	POSITIVE
DERL1	hsa-miR-19b-3p	Tarbase	external_info	Sequencing	POSITIVE
CUL5	hsa-miR-19b-3p	OncomiRDB	external_info	NA	NA	22561557

Predicted Targets

	Summary Value
Count of predictions:	34662
Count of gene targets:	10739
Count of transcripts:	22147
Interacting mature miRNAs:	hsa-miR-19b-2-5p, hsa-miR-19b-3p
Prediction methods:	Microtar, Miranda, Pita, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Expression

Sequence

Nucleotide Sequences

Clinical Variants

Additional Information

External Database Links

More on MIR19B2
	Alliance Gene
	NCBI Gene
	Ensembl Gene
	JBrowse: hg19 hg38
	HGNC Report
	NCBI Genome Data Viewer

RGD Object Information
RGD ID:	1347760
Created:	2005-03-08
Species:	Homo sapiens
Last Modified:	2020-09-08
Status:	ACTIVE

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Annotations - ClinVar