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Gene: LILRB4 (leukocyte immunoglobulin like receptor B4) Homo sapiens
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Symbol: LILRB4
Name: leukocyte immunoglobulin like receptor B4
Description: Predicted to have antigen binding activity and signaling receptor activity. Involved in several processes, including negative regulation of T cell receptor signaling pathway; negative regulation of pri-miRNA transcription by RNA polymerase II; and regulation of leukocyte differentiation. Localizes to the extracellular exosome.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CD85 antigen-like family member K; CD85K; HM18; ILT-3; ILT3; immunoglobulin-like transcript 3; leucocyte Ig-like receptor B4; leukocyte immunoglobulin-like receptor 5; leukocyte immunoglobulin-like receptor subfamily B member 4; leukocyte immunoglobulin-like receptor subfamily B member 4 soluble isoform; leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4; leukocyte immunoglobulin-like receptor, subfamily B, member 4; LILRB5; LIR-5; LIR5; monocyte inhibitory receptor HM18
Orthologs:
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381954,662,524 - 54,670,359 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371955,174,271 - 55,181,810 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361959,865,936 - 59,871,660 (+)NCBINCBI36hg18NCBI36
Build 341959,866,263 - 59,873,621NCBI
Celera1952,214,265 - 52,220,001 (+)NCBI
Cytogenetic Map19q13.42NCBI
HuRef1951,497,246 - 51,504,797 (+)NCBIHuRef
CHM1_11955,167,838 - 55,175,378 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on LILRB4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1347745
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.