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Gene: MSR1 (macrophage scavenger receptor 1) Homo sapiens
Symbol: MSR1
Name: macrophage scavenger receptor 1
Description: Predicted to have amyloid-beta binding activity; cargo receptor activity; and low-density lipoprotein particle binding activity. Predicted to be involved in several processes, including endocytosis; positive regulation of cholesterol storage; and positive regulation of macrophage derived foam cell differentiation. Predicted to localize to plasma membrane. Implicated in Barrett's esophagus; arteriosclerosis; and prostate cancer.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CD204; macrophage acetylated LDL receptor I and II; macrophage scavenger receptor type III; macrophage scavenger receptor types I and II; phSR1; phSR2; SCARA1; scavenger receptor class A member 1; scavenger receptor class A, member 1; SR-A; SR-AI; SR-AII; SR-AIII; SRA
Mus musculus (house mouse) : Msr1 (macrophage scavenger receptor 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Msr1 (macrophage scavenger receptor 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Msr1 (macrophage scavenger receptor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : MSR1 (macrophage scavenger receptor 1)
Canis lupus familiaris (dog) : MSR1 (macrophage scavenger receptor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Msr1 (macrophage scavenger receptor 1)
Sus scrofa (pig) : MSR1 (macrophage scavenger receptor 1)
Chlorocebus sabaeus (African green monkey) : MSR1 (macrophage scavenger receptor 1)
Heterocephalus glaber (naked mole-rat) : Msr1 (macrophage scavenger receptor 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl816,107,878 - 16,567,490 (-)EnsemblGRCh38hg38GRCh38
GRCh38816,107,878 - 16,192,791 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37815,965,387 - 16,050,300 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36816,009,758 - 16,094,671 (-)NCBINCBI36hg18NCBI36
Build 34816,009,760 - 16,094,595NCBI
Celera814,929,936 - 15,014,828 (-)NCBI
Cytogenetic Map8p22NCBI
HuRef814,509,923 - 14,594,638 (-)NCBIHuRef
CHM1_1816,167,312 - 16,251,899 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Candidate Gene Status
Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on MSR1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1347158
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.