Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 17beta-estradiol | decreases expression | ISO | Tram1 (Rattus norvegicus) | 6480464 | Estradiol results in decreased expression of TRAM1 mRNA | CTD | PMID:20068009 | 17beta-hydroxy-5alpha-androstan-3-one | increases expression | EXP | | 6480464 | Dihydrotestosterone results in increased expression of TRAM1 mRNA | CTD | PMID:29581250 | 2,2',4,4'-Tetrabromodiphenyl ether | affects expression | ISO | Tram1 (Mus musculus) | 6480464 | 2 more ... | CTD | PMID:30294300 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Tram1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of TRAM1 mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Tram1 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of TRAM1 mRNA | CTD | PMID:34747641 | 2-methylcholine | affects expression | EXP | | 6480464 | beta-methylcholine affects the expression of TRAM1 mRNA | CTD | PMID:21179406 | 4,4'-diaminodiphenylmethane | increases expression | ISO | Tram1 (Mus musculus) | 6480464 | 4 and 4'-diaminodiphenylmethane results in increased expression of TRAM1 mRNA | CTD | PMID:18648102 | 4,4'-diaminodiphenylmethane | decreases expression | ISO | Tram1 (Rattus norvegicus) | 6480464 | 4 and 4'-diaminodiphenylmethane results in decreased expression of TRAM1 mRNA | CTD | PMID:30723492 | 6-propyl-2-thiouracil | decreases expression | ISO | Tram1 (Rattus norvegicus) | 6480464 | Propylthiouracil results in decreased expression of TRAM1 mRNA | CTD | PMID:30047161 | 6-propyl-2-thiouracil | increases expression | ISO | Tram1 (Rattus norvegicus) | 6480464 | Propylthiouracil results in increased expression of TRAM1 mRNA | CTD | PMID:30047161 | acrolein | multiple interactions | EXP | | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of TRAM1 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of TRAM1 mRNA | CTD | PMID:32699268 | aflatoxin B1 | increases expression | EXP | | 6480464 | Aflatoxin B1 results in increased expression of TRAM1 mRNA | CTD | PMID:27153756 | alpha-pinene | multiple interactions | EXP | | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of TRAM1 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of TRAM1 mRNA | CTD | PMID:32699268 | amitrole | decreases expression | ISO | Tram1 (Rattus norvegicus) | 6480464 | Amitrole results in decreased expression of TRAM1 mRNA | CTD | PMID:30047161 | amitrole | increases expression | ISO | Tram1 (Rattus norvegicus) | 6480464 | Amitrole results in increased expression of TRAM1 mRNA | CTD | PMID:30047161 | aristolochic acid A | decreases expression | EXP | | 6480464 | aristolochic acid I results in decreased expression of TRAM1 mRNA | CTD | PMID:33212167 | Aroclor 1254 | decreases expression | ISO | Tram1 (Mus musculus) | 6480464 | Chlorodiphenyl (54% Chlorine) results in decreased expression of TRAM1 mRNA | CTD | PMID:23650126 | benzo[a]pyrene | increases mutagenesis | EXP | | 6480464 | Benzo(a)pyrene results in increased mutagenesis of TRAM1 gene | CTD | PMID:25435355 | benzo[a]pyrene | decreases methylation | EXP | | 6480464 | Benzo(a)pyrene results in decreased methylation of TRAM1 promoter | CTD | PMID:27901495 | benzo[a]pyrene | increases expression | ISO | Tram1 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of TRAM1 mRNA | CTD | PMID:22228805 | benzo[a]pyrene diol epoxide I | decreases expression | EXP | | 6480464 | 7 more ... | CTD | PMID:20018196 | bicalutamide | increases expression | EXP | | 6480464 | bicalutamide results in increased expression of TRAM1 mRNA | CTD | PMID:16631469 | bisphenol A | affects expression | ISO | Tram1 (Rattus norvegicus) | 6480464 | bisphenol A affects the expression of TRAM1 mRNA | CTD | PMID:25181051 | bisphenol A | decreases expression | ISO | Tram1 (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of TRAM1 mRNA | CTD | PMID:34947998 | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of TRAM1 mRNA | CTD | PMID:30903817 | cadmium atom | multiple interactions | ISO | Tram1 (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of TRAM1 mRNA | CTD | PMID:37325564 | cadmium dichloride | multiple interactions | ISO | Tram1 (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of TRAM1 mRNA | CTD | PMID:37325564 | carbon nanotube | increases expression | ISO | Tram1 (Mus musculus) | 6480464 | Nanotubes and Carbon results in increased expression of TRAM1 mRNA | CTD | PMID:25554681 | CGP 52608 | multiple interactions | EXP | | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to TRAM1 gene] | CTD | PMID:28238834 | chloropicrin | affects expression | EXP | | 6480464 | chloropicrin affects the expression of TRAM1 mRNA | CTD | PMID:26352163 | cisplatin | decreases expression | EXP | | 6480464 | Cisplatin results in decreased expression of TRAM1 mRNA | CTD | PMID:16061661 and PMID:27392435 | cisplatin | multiple interactions | EXP | | 6480464 | [Cisplatin co-treated with jinfukang] results in decreased expression of TRAM1 mRNA | CTD | PMID:27392435 | clofibrate | decreases expression | ISO | Tram1 (Mus musculus) | 6480464 | Clofibrate results in decreased expression of TRAM1 mRNA | CTD | PMID:17585979 | copper(II) sulfate | decreases expression | EXP | | 6480464 | Copper Sulfate results in decreased expression of TRAM1 mRNA | CTD | PMID:19549813 | coumarin | decreases phosphorylation | EXP | | 6480464 | coumarin results in decreased phosphorylation of TRAM1 protein | CTD | PMID:35688186 | CU-O LINKAGE | decreases expression | EXP | | 6480464 | cupric oxide results in decreased expression of TRAM1 mRNA | CTD | PMID:22077320 | cyclosporin A | increases expression | ISO | Tram1 (Mus musculus) | 6480464 | Cyclosporine results in increased expression of TRAM1 mRNA | CTD | PMID:25270620 | cyclosporin A | decreases methylation | EXP | | 6480464 | Cyclosporine results in decreased methylation of TRAM1 promoter | CTD | PMID:27989131 | cyclosporin A | increases expression | EXP | | 6480464 | Cyclosporine results in increased expression of TRAM1 mRNA | CTD | PMID:20106945 and PMID:21632981 | dicrotophos | decreases expression | EXP | | 6480464 | dicrotophos results in decreased expression of TRAM1 mRNA | CTD | PMID:28302478 | doxorubicin | decreases expression | EXP | | 6480464 | Doxorubicin results in decreased expression of TRAM1 mRNA | CTD | PMID:29803840 | endosulfan | decreases expression | ISO | Tram1 (Rattus norvegicus) | 6480464 | Endosulfan results in decreased expression of TRAM1 mRNA | CTD | PMID:29391264 | endosulfan | increases expression | ISO | Tram1 (Rattus norvegicus) | 6480464 | Endosulfan results in increased expression of TRAM1 mRNA | CTD | PMID:31464424 | ethanol | multiple interactions | EXP | | 6480464 | [[Gasoline co-treated with Ethanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in decreased expression of TRAM1 mRNA | CTD | PMID:29432896 | fenthion | decreases expression | ISO | Tram1 (Mus musculus) | 6480464 | Fenthion results in decreased expression of TRAM1 mRNA | CTD | PMID:34813904 | folic acid | decreases expression | ISO | Tram1 (Mus musculus) | 6480464 | Folic Acid results in decreased expression of TRAM1 mRNA | CTD | PMID:25629700 | FR900359 | decreases phosphorylation | EXP | | 6480464 | FR900359 results in decreased phosphorylation of TRAM1 protein | CTD | PMID:37730182 | ivermectin | decreases expression | EXP | | 6480464 | Ivermectin results in decreased expression of TRAM1 protein | CTD | PMID:32959892 | kojic acid | decreases expression | EXP | | 6480464 | kojic acid results in decreased expression of TRAM1 mRNA | CTD | PMID:16595896 | methimazole | decreases expression | ISO | Tram1 (Rattus norvegicus) | 6480464 | Methimazole results in decreased expression of TRAM1 mRNA | CTD | PMID:30047161 | methimazole | increases expression | ISO | Tram1 (Rattus norvegicus) | 6480464 | Methimazole results in increased expression of TRAM1 mRNA | CTD | PMID:30047161 | methyl methanesulfonate | decreases expression | EXP | | 6480464 | Methyl Methanesulfonate results in decreased expression of TRAM1 mRNA | CTD | PMID:23649840 | N-methyl-N'-nitro-N-nitrosoguanidine | increases expression | EXP | | 6480464 | Methylnitronitrosoguanidine results in increased expression of TRAM1 mRNA | CTD | PMID:12634122 | nickel atom | increases expression | EXP | | 6480464 | Nickel results in increased expression of TRAM1 mRNA | CTD | PMID:25583101 | ozone | multiple interactions | EXP | | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of TRAM1 mRNA more ... | CTD | PMID:32699268 | paracetamol | increases expression | ISO | Tram1 (Mus musculus) | 6480464 | Acetaminophen results in increased expression of TRAM1 mRNA | CTD | PMID:29246445 | paracetamol | multiple interactions | ISO | Tram1 (Mus musculus) | 6480464 | PANX1 gene mutant form inhibits the reaction [Acetaminophen results in increased expression of TRAM1 mRNA] | CTD | PMID:29246445 | PhIP | increases expression | ISO | Tram1 (Rattus norvegicus) | 6480464 | 2-amino-1-methyl-6-phenylimidazo(4 and 5-b)pyridine results in increased expression of TRAM1 mRNA | CTD | PMID:15215175 | picoxystrobin | increases expression | EXP | | 6480464 | picoxystrobin results in increased expression of TRAM1 mRNA | CTD | PMID:33512557 | pirinixic acid | decreases expression | ISO | Tram1 (Mus musculus) | 6480464 | pirinixic acid results in decreased expression of TRAM1 mRNA | CTD | PMID:23811191 | propiconazole | increases expression | ISO | Tram1 (Mus musculus) | 6480464 | propiconazole results in increased expression of TRAM1 mRNA | CTD | PMID:21278054 | resveratrol | increases expression | ISO | Tram1 (Mus musculus) | 6480464 | resveratrol results in increased expression of TRAM1 protein | CTD | PMID:25505154 | serpentine asbestos | increases expression | ISO | Tram1 (Mus musculus) | 6480464 | Asbestos and Serpentine results in increased expression of TRAM1 mRNA | CTD | PMID:16251409 | sodium arsenite | decreases expression | EXP | | 6480464 | sodium arsenite results in decreased expression of TRAM1 mRNA | CTD | PMID:28595984 and PMID:34032870 | sodium arsenite | multiple interactions | EXP | | 6480464 | sodium arsenite promotes the reaction [TRAM1 protein binds to CAPRIN1 protein] | CTD | PMID:33939924 | sodium arsenite | decreases methylation | ISO | Tram1 (Mus musculus) | 6480464 | sodium arsenite results in decreased methylation of TRAM1 gene | CTD | PMID:32068019 | sulfadimethoxine | increases expression | ISO | Tram1 (Rattus norvegicus) | 6480464 | Sulfadimethoxine results in increased expression of TRAM1 mRNA | CTD | PMID:30047161 | tert-butyl hydroperoxide | decreases expression | EXP | | 6480464 | tert-Butylhydroperoxide results in decreased expression of TRAM1 mRNA | CTD | PMID:15336504 | tetrachloromethane | increases expression | ISO | Tram1 (Mus musculus) | 6480464 | Carbon Tetrachloride results in increased expression of TRAM1 mRNA | CTD | PMID:31919559 | thapsigargin | increases expression | EXP | | 6480464 | Thapsigargin results in increased expression of TRAM1 mRNA | CTD | PMID:22378314 and PMID:29453283 | thimerosal | increases expression | EXP | | 6480464 | Thimerosal results in increased expression of TRAM1 mRNA | CTD | PMID:27188386 | titanium dioxide | increases expression | ISO | Tram1 (Mus musculus) | 6480464 | titanium dioxide results in increased expression of TRAM1 mRNA | CTD | PMID:27760801 | triadimefon | increases expression | ISO | Tram1 (Rattus norvegicus) | 6480464 | triadimefon results in increased expression of TRAM1 mRNA | CTD | PMID:30047161 | Triptolide | increases expression | ISO | Tram1 (Rattus norvegicus) | 6480464 | triptolide results in increased expression of TRAM1 protein | CTD | PMID:32519852 | triptonide | increases expression | ISO | Tram1 (Mus musculus) | 6480464 | triptonide results in increased expression of TRAM1 mRNA | CTD | PMID:33045310 | tunicamycin | increases expression | EXP | | 6480464 | Tunicamycin results in increased expression of TRAM1 mRNA | CTD | PMID:22378314 and PMID:29453283 | valproic acid | decreases methylation | EXP | | 6480464 | Valproic Acid results in decreased methylation of TRAM1 gene | CTD | PMID:29154799 | valproic acid | decreases expression | EXP | | 6480464 | Valproic Acid results in decreased expression of TRAM1 mRNA | CTD | PMID:29154799 | vorinostat | increases expression | EXP | | 6480464 | vorinostat results in increased expression of TRAM1 mRNA | CTD | PMID:27188386 | |