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Gene: CXADR (CXADR Ig-like cell adhesion molecule) Homo sapiens
Symbol: CXADR
Name: CXADR Ig-like cell adhesion molecule
RGD ID: 1346916
Description: Exhibits several functions, including PDZ domain binding activity; beta-catenin binding activity; and integrin binding activity. Involved in several processes, including actin cytoskeleton reorganization; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules; and neutrophil chemotaxis. Localizes to several cellular components, including apicolateral plasma membrane; basolateral plasma membrane; and bicellular tight junction.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 46 kD coxsackievirus and adenovirus receptor (CAR) protein; CAR; CAR4/6; coxsackie virus and adenovirus receptor; coxsackie virus B receptor; coxsackievirus and adenovirus receptor; coxsackievirus B-adenovirus receptor; CVB3 binding protein; CVB3-binding protein; CXADR, Ig-like cell adhesion molecule; HCAR; HCVADR
Mus musculus (house mouse) : Cxadr (coxsackie virus and adenovirus receptor)  MGI  Alliance
Rattus norvegicus (Norway rat) : Cxadr (CXADR, Ig-like cell adhesion molecule)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cxadr (CXADR Ig-like cell adhesion molecule)
Pan paniscus (bonobo/pygmy chimpanzee) : CXADR (CXADR Ig-like cell adhesion molecule)
Canis lupus familiaris (dog) : CXADR (CXADR Ig-like cell adhesion molecule)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cxadr (CXADR Ig-like cell adhesion molecule)
Sus scrofa (pig) : CXADR (CXADR Ig-like cell adhesion molecule)
Chlorocebus sabaeus (African green monkey) : CXADR (CXADR Ig-like cell adhesion molecule)
Heterocephalus glaber (naked mole-rat) : Cxadr (CXADR Ig-like cell adhesion molecule)
more info ...
Related Pseudogenes: AC012414.6   CXADRP1   CXADRP2   CXADRP3   LOC102724726  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl2117,513,043 - 17,593,579 (+)EnsemblGRCh38hg38GRCh38
GRCh382117,513,016 - 17,636,213 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372118,885,224 - 18,965,897 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362117,807,201 - 17,861,147 (+)NCBINCBI36hg18NCBI36
Build 342117,807,200 - 17,861,135NCBI
Celera214,060,105 - 4,114,040 (+)NCBI
Cytogenetic Map21q21.1NCBI
HuRef214,271,028 - 4,351,637 (+)NCBIHuRef
CHM1_12118,445,887 - 18,526,468 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on CXADR
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1346916
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-10-06
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.