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Gene: NIT2 (nitrilase family member 2) Homo sapiens
Symbol: NIT2
Name: nitrilase family member 2
RGD ID: 1346727
Description: Exhibits omega-amidase activity. Involved in asparagine metabolic process; glutamine metabolic process; and oxaloacetate metabolic process. Localizes to centrosome and cytosol; PARTICIPATES IN alanine, aspartate and glutamate metabolic pathway; INTERACTS WITH (+)-catechin; 2-hydroxypropanoic acid; atrazine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: epididymis secretory sperm binding protein Li 8a; HEL-S-8a; MGC111199; Nit protein 2; nitrilase family, member 2; nitrilase homolog 2; omega-amidase NIT2
Mus musculus (house mouse) : Nit2 (nitrilase family, member 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Nit2 (nitrilase family, member 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nit2 (nitrilase family member 2)
Pan paniscus (bonobo/pygmy chimpanzee) : NIT2 (nitrilase family member 2)
Canis lupus familiaris (dog) : NIT2 (nitrilase family member 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nit2 (nitrilase family member 2)
Sus scrofa (pig) : NIT2 (nitrilase family member 2)
Chlorocebus sabaeus (African green monkey) : NIT2 (nitrilase family member 2)
Heterocephalus glaber (naked mole-rat) : Nit2 (nitrilase family member 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl3100,334,739 - 100,361,635 (+)EnsemblGRCh38hg38GRCh38
GRCh383100,334,757 - 100,361,635 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh373100,053,483 - 100,075,844 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363101,536,258 - 101,556,883 (+)NCBINCBI36hg18NCBI36
Build 343101,536,257 - 101,556,881NCBI
Celera398,444,355 - 98,465,336 (+)NCBI
Cytogenetic Map3q12.2NCBI
HuRef397,421,355 - 97,442,271 (+)NCBIHuRef
CHM1_13100,016,590 - 100,037,506 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on NIT2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1346727
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-09-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.