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Gene: KLHL12 (kelch like family member 12) Homo sapiens
Symbol: KLHL12
Name: kelch like family member 12
Description: Exhibits identical protein binding activity. Involved in several processes, including COPII vesicle coating; mesenchymal cell differentiation; and protein monoubiquitination. Localizes to several cellular components, including the COPII vesicle coat; Cul3-RING ubiquitin ligase complex; and centriolar satellite.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: C3IP1; CUL3-interacting protein 1; DKIR; DKIR homolog; FLJ27152; hDKIR; kelch-like 12; kelch-like family member 12; kelch-like protein 12; kelch-like protein C3IP1
Mus musculus (house mouse) : Klhl12 (kelch-like 12)  MGI  Alliance
Rattus norvegicus (Norway rat) : Klhl12 (kelch-like family member 12)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Klhl12 (kelch like family member 12)
Pan paniscus (bonobo/pygmy chimpanzee) : KLHL12 (kelch like family member 12)
Canis lupus familiaris (dog) : KLHL12 (kelch like family member 12)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Klhl12 (kelch like family member 12)
Sus scrofa (pig) : KLHL12 (kelch like family member 12)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh381202,891,116 - 202,928,628 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371202,860,230 - 202,897,766 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361201,126,853 - 201,162,994 (-)NCBINCBI36hg18NCBI36
Build 341199,591,886 - 199,628,028NCBI
Celera1175,989,447 - 176,025,617 (-)NCBI
Cytogenetic Map1q32.1NCBI
HuRef1174,025,817 - 174,061,990 (-)NCBIHuRef
CHM1_11204,282,473 - 204,320,006 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on KLHL12
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1346633
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-10-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.