Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dichloroethane | decreases expression | ISO | Pcdhac2 (Mus musculus) | 6480464 | ethylene dichloride results in decreased expression of PCDHAC2 mRNA | CTD | PMID:28960355 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Pcdhac2 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of PCDHAC2 mRNA | CTD | PMID:33387578 | 3,4-methylenedioxymethamphetamine | increases expression | ISO | Pcdhac2 (Rattus norvegicus) | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in increased expression of PCDHAC2 mRNA | CTD | PMID:30071829 | 4,4'-sulfonyldiphenol | decreases expression | ISO | Pcdhac2 (Mus musculus) | 6480464 | bisphenol S results in decreased expression of PCDHAC2 mRNA | CTD | PMID:30951980 | 6-propyl-2-thiouracil | decreases expression | ISO | Pcdhac2 (Rattus norvegicus) | 6480464 | Propylthiouracil results in decreased expression of PCDHAC2 mRNA | CTD | PMID:30047161 | amiodarone | increases expression | EXP | | 6480464 | Amiodarone results in increased expression of PCDHAC2 mRNA | CTD | PMID:19774075 | amitrole | decreases expression | ISO | Pcdhac2 (Rattus norvegicus) | 6480464 | Amitrole results in decreased expression of PCDHAC2 mRNA | CTD | PMID:30047161 | ammonium chloride | affects expression | ISO | Pcdhac2 (Rattus norvegicus) | 6480464 | Ammonium Chloride affects the expression of PCDHAC2 mRNA | CTD | PMID:16483693 | amosite asbestos | decreases methylation | EXP | | 6480464 | Asbestos and Amosite results in decreased methylation of PCDHAC2 promoter | CTD | PMID:29626692 | arsenite(3-) | increases methylation | EXP | | 6480464 | arsenite results in increased methylation of PCDHAC2 promoter | CTD | PMID:23974009 | benzo[a]pyrene | increases expression | EXP | | 6480464 | Benzo(a)pyrene results in increased expression of PCDHAC2 mRNA | CTD | PMID:22316170 and PMID:32234424 | benzo[a]pyrene | increases methylation | EXP | | 6480464 | Benzo(a)pyrene results in increased methylation of PCDHAC2 exon | CTD | PMID:27901495 | benzo[a]pyrene | multiple interactions | ISO | Pcdhac2 (Mus musculus) | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of PCDHAC2 mRNA | CTD | PMID:27858113 | benzo[b]fluoranthene | decreases expression | ISO | Pcdhac2 (Mus musculus) | 6480464 | benzo(b)fluoranthene results in decreased expression of PCDHAC2 mRNA | CTD | PMID:26377693 | benzo[b]fluoranthene | multiple interactions | ISO | Pcdhac2 (Mus musculus) | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of PCDHAC2 mRNA | CTD | PMID:27858113 | bisphenol A | decreases expression | ISO | Pcdhac2 (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of PCDHAC2 mRNA | CTD | PMID:25181051 | bisphenol A | decreases expression | ISO | Pcdhac2 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of PCDHAC2 mRNA | CTD | PMID:30951980 | bisphenol F | decreases expression | ISO | Pcdhac2 (Mus musculus) | 6480464 | bisphenol F results in decreased expression of PCDHAC2 mRNA | CTD | PMID:30951980 | carbon nanotube | decreases expression | ISO | Pcdhac2 (Mus musculus) | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | CGP 52608 | multiple interactions | EXP | | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to PCDHAC2 gene] | CTD | PMID:28238834 | choline | multiple interactions | ISO | Pcdhac2 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of PCDHAC2 gene | CTD | PMID:20938992 | chrysene | multiple interactions | ISO | Pcdhac2 (Mus musculus) | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of PCDHAC2 mRNA | CTD | PMID:27858113 | copper(II) sulfate | decreases expression | EXP | | 6480464 | Copper Sulfate results in decreased expression of PCDHAC2 mRNA | CTD | PMID:19549813 | crocidolite asbestos | decreases methylation | EXP | | 6480464 | Asbestos and Crocidolite results in decreased methylation of PCDHAC2 promoter | CTD | PMID:29626692 | cyclosporin A | increases expression | EXP | | 6480464 | Cyclosporine results in increased expression of PCDHAC2 mRNA | CTD | PMID:20106945 | dibenz[a,h]anthracene | decreases expression | ISO | Pcdhac2 (Mus musculus) | 6480464 | 1 more ... | CTD | PMID:26377693 | dioxygen | decreases expression | EXP | | 6480464 | Oxygen deficiency results in decreased expression of PCDHAC2 mRNA | CTD | PMID:26516004 | ethanol | increases expression | ISO | Pcdhac2 (Mus musculus) | 6480464 | Ethanol results in increased expression of PCDHAC2 mRNA | CTD | PMID:30319688 | ethylparaben | increases expression | EXP | | 6480464 | ethyl-p-hydroxybenzoate results in increased expression of PCDHAC2 mRNA | CTD | PMID:37690743 | folic acid | multiple interactions | ISO | Pcdhac2 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of PCDHAC2 gene | CTD | PMID:20938992 | furan | increases expression | ISO | Pcdhac2 (Rattus norvegicus) | 6480464 | furan results in increased expression of PCDHAC2 mRNA | CTD | PMID:27387713 | gentamycin | decreases expression | ISO | Pcdhac2 (Rattus norvegicus) | 6480464 | Gentamicins results in decreased expression of PCDHAC2 mRNA | CTD | PMID:33387578 | glyphosate | decreases expression | ISO | Pcdhac2 (Mus musculus) | 6480464 | Glyphosate results in decreased expression of PCDHAC2 mRNA | CTD | PMID:35489704 | L-methionine | multiple interactions | ISO | Pcdhac2 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of PCDHAC2 gene | CTD | PMID:20938992 | lead(0) | affects expression | EXP | | 6480464 | Lead affects the expression of PCDHAC2 mRNA | CTD | PMID:28903495 | lipopolysaccharide | decreases expression | ISO | Pcdhac2 (Mus musculus) | 6480464 | Lipopolysaccharides results in decreased expression of PCDHAC2 mRNA | CTD | PMID:30942577 | methimazole | decreases expression | ISO | Pcdhac2 (Rattus norvegicus) | 6480464 | Methimazole results in decreased expression of PCDHAC2 mRNA | CTD | PMID:30047161 | methylmercury chloride | decreases expression | EXP | | 6480464 | methylmercuric chloride results in decreased expression of PCDHAC2 mRNA | CTD | PMID:28001369 | N-Nitrosopyrrolidine | increases expression | EXP | | 6480464 | N-Nitrosopyrrolidine results in increased expression of PCDHAC2 mRNA | CTD | PMID:32234424 | O-methyleugenol | increases expression | EXP | | 6480464 | methyleugenol results in increased expression of PCDHAC2 mRNA | CTD | PMID:32234424 | ozone | multiple interactions | ISO | Pcdhac2 (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of PCDHAC2 mRNA and [Air Pollutants results in increased abundance of Ozone] which results in decreased expression of PCDHAC2 mRNA | CTD | PMID:27106289 and PMID:34911549 | paracetamol | decreases expression | ISO | Pcdhac2 (Rattus norvegicus) | 6480464 | Acetaminophen results in decreased expression of PCDHAC2 mRNA | CTD | PMID:33387578 | perfluorononanoic acid | increases expression | EXP | | 6480464 | perfluoro-n-nonanoic acid results in increased expression of PCDHAC2 mRNA | CTD | PMID:32588087 | phenylmercury acetate | increases expression | EXP | | 6480464 | Phenylmercuric Acetate results in increased expression of PCDHAC2 mRNA | CTD | PMID:26272509 | serpentine asbestos | affects methylation | EXP | | 6480464 | Asbestos and Serpentine affects the methylation of PCDHAC2 5' UTR | CTD | PMID:29523930 | sulfadimethoxine | decreases expression | ISO | Pcdhac2 (Rattus norvegicus) | 6480464 | Sulfadimethoxine results in decreased expression of PCDHAC2 mRNA | CTD | PMID:30047161 | sunitinib | decreases expression | EXP | | 6480464 | Sunitinib results in decreased expression of PCDHAC2 mRNA | CTD | PMID:31533062 | tetrachloromethane | decreases expression | ISO | Pcdhac2 (Rattus norvegicus) | 6480464 | Carbon Tetrachloride results in decreased expression of PCDHAC2 mRNA | CTD | PMID:31150632 | tetraphene | multiple interactions | ISO | Pcdhac2 (Mus musculus) | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of PCDHAC2 mRNA | CTD | PMID:27858113 | tetraphene | increases expression | ISO | Pcdhac2 (Mus musculus) | 6480464 | benz(a)anthracene results in increased expression of PCDHAC2 mRNA | CTD | PMID:26377693 | titanium dioxide | decreases expression | ISO | Pcdhac2 (Mus musculus) | 6480464 | titanium dioxide results in decreased expression of PCDHAC2 mRNA | CTD | PMID:29264374 | |