Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (-)-alpha-phellandrene | increases expression | EXP | | 6480464 | alpha phellandrene results in increased expression of WDSUB1 mRNA | CTD | PMID:25075043 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of WDSUB1 mRNA | CTD | PMID:17101203 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Wdsub1 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of WDSUB1 mRNA | CTD | PMID:32109520 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of WDSUB1 mRNA | CTD | PMID:20106945 and PMID:21632981 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Wdsub1 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of WDSUB1 mRNA | CTD | PMID:21215274 and PMID:33387578 | 2,4-dibromophenyl 2,4,5-tribromophenyl ether | increases expression | EXP | | 6480464 | 2 more ... | CTD | PMID:26705709 | 2,6-dinitrotoluene | affects expression | ISO | Wdsub1 (Rattus norvegicus) | 6480464 | 2 and 6-dinitrotoluene affects the expression of WDSUB1 mRNA | CTD | PMID:21346803 | 3,4-methylenedioxymethamphetamine | decreases expression | ISO | Wdsub1 (Mus musculus) | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased expression of WDSUB1 mRNA | CTD | PMID:26251327 | 3,4-methylenedioxymethamphetamine | increases methylation | ISO | Wdsub1 (Mus musculus) | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in increased methylation of WDSUB1 promoter | CTD | PMID:26251327 | 4-hydroxyphenyl retinamide | decreases expression | ISO | Wdsub1 (Mus musculus) | 6480464 | Fenretinide results in decreased expression of WDSUB1 mRNA | CTD | PMID:28973697 | 5-aza-2'-deoxycytidine | affects expression | EXP | | 6480464 | Decitabine affects the expression of WDSUB1 mRNA | CTD | PMID:23300844 | 6-propyl-2-thiouracil | increases expression | ISO | Wdsub1 (Rattus norvegicus) | 6480464 | Propylthiouracil results in increased expression of WDSUB1 mRNA | CTD | PMID:24780913 | 6-propyl-2-thiouracil | decreases expression | ISO | Wdsub1 (Rattus norvegicus) | 6480464 | Propylthiouracil results in decreased expression of WDSUB1 mRNA | CTD | PMID:30047161 | acrolein | multiple interactions | EXP | | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of WDSUB1 mRNA more ... | CTD | PMID:32699268 and PMID:32845096 | alpha-phellandrene | increases expression | EXP | | 6480464 | alpha phellandrene results in increased expression of WDSUB1 mRNA | CTD | PMID:25075043 | alpha-pinene | multiple interactions | EXP | | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of WDSUB1 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased expression of WDSUB1 mRNA | CTD | PMID:32699268 | amitrole | decreases expression | ISO | Wdsub1 (Rattus norvegicus) | 6480464 | Amitrole results in decreased expression of WDSUB1 mRNA | CTD | PMID:30047161 | benzo[a]pyrene | increases methylation | EXP | | 6480464 | Benzo(a)pyrene results in increased methylation of WDSUB1 promoter | CTD | PMID:27901495 | benzo[a]pyrene | affects methylation | EXP | | 6480464 | Benzo(a)pyrene affects the methylation of WDSUB1 5' UTR | CTD | PMID:27901495 | bisphenol A | increases expression | ISO | Wdsub1 (Rattus norvegicus) | 6480464 | bisphenol A results in increased expression of WDSUB1 mRNA | CTD | PMID:25181051 | cadmium atom | increases expression | EXP | | 6480464 | Cadmium results in increased expression of WDSUB1 mRNA | CTD | PMID:24376830 | calcitriol | increases expression | EXP | | 6480464 | Calcitriol results in increased expression of WDSUB1 mRNA | CTD | PMID:16002434 | chlorpyrifos | increases expression | ISO | Wdsub1 (Mus musculus) | 6480464 | Chlorpyrifos results in increased expression of WDSUB1 mRNA | CTD | PMID:37019170 | cisplatin | affects expression | EXP | | 6480464 | Cisplatin affects the expression of WDSUB1 mRNA | CTD | PMID:23300844 | copper(II) sulfate | decreases expression | EXP | | 6480464 | Copper Sulfate results in decreased expression of WDSUB1 mRNA | CTD | PMID:19549813 | cyclosporin A | increases expression | EXP | | 6480464 | Cyclosporine results in increased expression of WDSUB1 mRNA | CTD | PMID:20106945 | dorsomorphin | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of WDSUB1 mRNA | CTD | PMID:27188386 | ethyl methanesulfonate | increases expression | EXP | | 6480464 | Ethyl Methanesulfonate results in increased expression of WDSUB1 mRNA | CTD | PMID:23649840 | fenthion | increases expression | ISO | Wdsub1 (Mus musculus) | 6480464 | Fenthion results in increased expression of WDSUB1 mRNA | CTD | PMID:34813904 | formaldehyde | increases expression | EXP | | 6480464 | Formaldehyde results in increased expression of WDSUB1 mRNA | CTD | PMID:23649840 | methimazole | decreases expression | ISO | Wdsub1 (Rattus norvegicus) | 6480464 | Methimazole results in decreased expression of WDSUB1 mRNA | CTD | PMID:30047161 | methyl methanesulfonate | increases expression | EXP | | 6480464 | Methyl Methanesulfonate results in increased expression of WDSUB1 mRNA | CTD | PMID:23649840 | methylmercury chloride | decreases expression | EXP | | 6480464 | methylmercuric chloride results in decreased expression of WDSUB1 mRNA | CTD | PMID:23179753 and PMID:27188386 | nickel atom | decreases expression | EXP | | 6480464 | Nickel results in decreased expression of WDSUB1 mRNA | CTD | PMID:25583101 | ozone | multiple interactions | EXP | | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of WDSUB1 mRNA more ... | CTD | PMID:32699268 and PMID:32845096 | phenobarbital | affects expression | ISO | Wdsub1 (Mus musculus) | 6480464 | Phenobarbital affects the expression of WDSUB1 mRNA | CTD | PMID:23091169 | quercetin | decreases expression | EXP | | 6480464 | Quercetin results in decreased expression of WDSUB1 mRNA | CTD | PMID:21632981 | SB 431542 | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of WDSUB1 mRNA | CTD | PMID:27188386 | sodium arsenite | decreases expression | EXP | | 6480464 | sodium arsenite results in decreased expression of WDSUB1 mRNA and sodium arsenite results in decreased expression of WDSUB1 protein | CTD | PMID:21925251 and PMID:34032870 | sulfadimethoxine | decreases expression | ISO | Wdsub1 (Rattus norvegicus) | 6480464 | Sulfadimethoxine results in decreased expression of WDSUB1 mRNA | CTD | PMID:30047161 | sunitinib | increases expression | EXP | | 6480464 | Sunitinib results in increased expression of WDSUB1 mRNA | CTD | PMID:31533062 | temozolomide | decreases expression | EXP | | 6480464 | Temozolomide results in decreased expression of WDSUB1 mRNA | CTD | PMID:31758290 | thioacetamide | decreases expression | ISO | Wdsub1 (Rattus norvegicus) | 6480464 | Thioacetamide results in decreased expression of WDSUB1 mRNA | CTD | PMID:34492290 | troglitazone | decreases expression | ISO | Wdsub1 (Mus musculus) | 6480464 | troglitazone results in decreased expression of WDSUB1 mRNA | CTD | PMID:28973697 | tunicamycin | increases expression | EXP | | 6480464 | Tunicamycin results in increased expression of WDSUB1 mRNA | CTD | PMID:29453283 | valproic acid | affects expression | EXP | | 6480464 | Valproic Acid affects the expression of WDSUB1 mRNA | CTD | PMID:25979313 | valproic acid | decreases methylation | EXP | | 6480464 | Valproic Acid results in decreased methylation of WDSUB1 gene | CTD | PMID:29154799 | valproic acid | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of WDSUB1 mRNA | CTD | PMID:27188386 | valproic acid | increases expression | EXP | | 6480464 | Valproic Acid results in increased expression of WDSUB1 mRNA | CTD | PMID:26272509 more ... | | 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Gene Ontology Annotations Click to see Annotation Detail View
Biological Process
Molecular Function
Phenotype Annotations Click to see Annotation Detail View
Imported Human Phenotype Annotations - ClinVar
Disease Annotations
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Gene-Chemical Interaction Annotations
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Gene Ontology Annotations
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Phenotype Annotations
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References
References - curated
| # | Reference Title | Reference Citation |
| 1. | GOAs Human GO annotations | GOA_HUMAN data from the GO Consortium |
| 2. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
| 3. | Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. | Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11. |
Additional References at PubMed
| PMID:8889548 | PMID:11329013 | PMID:14702039 | PMID:15489334 | PMID:15815621 | PMID:20979629 | PMID:23940030 | PMID:34299191 | PMID:35256949 | PMID:35831314 |
Genomics
Comparative Map Data
| WDSUB1 (Homo sapiens - human) |
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| Wdsub1 (Mus musculus - house mouse) |
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| Wdsub1 (Rattus norvegicus - Norway rat) |
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| Wdsub1 (Chinchilla lanigera - long-tailed chinchilla) |
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| WDSUB1 (Pan paniscus - bonobo/pygmy chimpanzee) |
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| WDSUB1 (Canis lupus familiaris - dog) |
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| Wdsub1 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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| WDSUB1 (Sus scrofa - pig) |
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| WDSUB1 (Chlorocebus sabaeus - green monkey) |
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| Wdsub1 (Heterocephalus glaber - naked mole-rat) |
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Variants
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Variants in WDSUB1
20 total Variants 
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