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Gene: TCIM (transcriptional and immune response regulator) Homo sapiens
Symbol: TCIM
Name: transcriptional and immune response regulator
Description: Exhibits Notch binding activity. Involved in several processes, including endothelial cell activation involved in immune response; positive regulation of protein kinase C activity; and regulation of signal transduction. Localizes to the cytosol; nuclear lumen; and plasma membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: C8orf4; chromosome 8 open reading frame 4; hTC-1; human thyroid cancer 1; MGC22806; TC-1; TC1; thyroid cancer protein 1; thyroid cancer-1; uncharacterized protein C8orf4
Mus musculus (house mouse) : Tcim (transcriptional and immune response regulator)  MGI  Alliance
Rattus norvegicus (Norway rat) : Tcim (transcriptional and immune response regulator)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tcim (transcriptional and immune response regulator)
Pan paniscus (bonobo/pygmy chimpanzee) : TCIM (transcriptional and immune response regulator)
Canis lupus familiaris (dog) : TCIM (transcriptional and immune response regulator)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tcim (transcriptional and immune response regulator)
Sus scrofa (pig) : TCIM (transcriptional and immune response regulator)
Chlorocebus sabaeus (green monkey) : TCIM (transcriptional and immune response regulator)
Heterocephalus glaber (naked mole-rat) : Tcim (transcriptional and immune response regulator)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl840,153,482 - 40,155,310 (+)Ensembl
GRCh38840,153,482 - 40,155,310 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37840,010,987 - 40,012,827 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36840,130,146 - 40,131,978 (+)NCBINCBI36hg18NCBI36
Build 34840,130,143 - 40,131,599NCBI
Celera838,962,805 - 38,964,636 (+)NCBI
Cytogenetic Map8p11.21NCBI
HuRef838,544,322 - 38,546,161 (+)NCBIHuRef
CHM1_1840,057,852 - 40,059,691 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on TCIM
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1346279
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.