SERPINA5 (serpin family A member 5) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: SERPINA5 (serpin family A member 5) Homo sapiens
Analyze
Symbol: SERPINA5
Name: serpin family A member 5
RGD ID: 1346137
HGNC Page HGNC:8723
Description: Enables enzyme binding activity; ion binding activity; and serine-type endopeptidase inhibitor activity. Predicted to be involved in spermatogenesis. Located in several cellular components, including external side of plasma membrane; extracellular exosome; and secretory granule. Part of several cellular components, including protein C inhibitor-KLK3 complex; protein C inhibitor-PLAT complex; and protein C inhibitor-PLAU complex.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: acrosomal serine protease inhibitor; PAI-3; PAI3; PCI; PCI-B; PLANH3; plasma serine protease inhibitor; plasminogen activator inhibitor 3; plasminogen activator inhibitor III; plasminogen activator inhibitor-3; PROCI; protein C inhibitor; serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5; serpin A5; serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381494,581,426 - 94,593,118 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1494,561,442 - 94,593,118 (+)EnsemblGRCh38hg38GRCh38
GRCh371495,047,763 - 95,059,455 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361494,117,564 - 94,129,205 (+)NCBINCBI36Build 36hg18NCBI36
Build 341494,117,563 - 94,129,204NCBI
Celera1475,103,903 - 75,115,619 (+)NCBICelera
Cytogenetic Map14q32.13NCBI
HuRef1475,228,133 - 75,239,873 (+)NCBIHuRef
CHM1_11494,985,498 - 94,997,214 (+)NCBICHM1_1
T2T-CHM13v2.01488,811,397 - 88,823,118 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1-naphthyl isothiocyanate  (EXP,ISO)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (EXP,ISO)
2,3,4,7,8-Pentachlorodibenzofuran  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
2,3-dimethoxynaphthalene-1,4-dione  (EXP)
4,4'-diaminodiphenylmethane  (ISO)
5-fluorouracil  (EXP)
6-propyl-2-thiouracil  (ISO)
aflatoxin B1  (EXP)
all-trans-retinoic acid  (EXP,ISO)
ammonium chloride  (ISO)
amphotericin B  (EXP)
benzo[a]pyrene  (EXP,ISO)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
C60 fullerene  (ISO)
cadmium atom  (EXP)
calcitriol  (EXP)
carbon nanotube  (ISO)
copper(II) sulfate  (EXP)
cyclosporin A  (EXP)
cylindrospermopsin  (EXP)
dextran sulfate  (EXP)
dibutyl phthalate  (ISO)
dorsomorphin  (EXP)
endosulfan  (ISO)
entinostat  (EXP)
ethanol  (EXP)
ethylparaben  (EXP)
fenvalerate  (ISO)
genistein  (ISO)
glyphosate  (ISO)
hydrogen peroxide  (EXP)
hydroquinone O-beta-D-glucopyranoside  (EXP)
kojic acid  (EXP)
levonorgestrel  (EXP)
methamphetamine  (EXP)
methotrexate  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
N-nitrosodimethylamine  (EXP)
nickel atom  (EXP)
paracetamol  (EXP)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP)
SB 431542  (EXP)
silicon dioxide  (EXP)
sodium arsenite  (ISO)
sodium fluoride  (ISO)
sotorasib  (EXP)
tamoxifen  (EXP)
temozolomide  (EXP)
thioacetamide  (ISO)
trametinib  (EXP)
triclosan  (EXP)
triphenyl phosphate  (ISO)
valproic acid  (EXP)
vorinostat  (EXP)
zinc atom  (EXP)
zinc(0)  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Assessment of gene expression profiles in peripheral occlusive arterial disease. Bubenek S, etal., Can J Cardiol. 2012 Nov-Dec;28(6):712-20. doi: 10.1016/j.cjca.2012.03.013. Epub 2012 Jun 19.
2. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
3. Basic mechanisms and regulation of fibrinolysis. Longstaff C and Kolev K, J Thromb Haemost. 2015 Jun;13 Suppl 1:S98-105. doi: 10.1111/jth.12935.
4. Protein C inhibitor (plasminogen activator inhibitor-3) and the risk of venous thrombosis. Meijers JC, etal., Br J Haematol. 2002 Aug;118(2):604-9.
5. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:1318261   PMID:1372913   PMID:1714450   PMID:1725227   PMID:2172989   PMID:2173165   PMID:2551064   PMID:2556811   PMID:2752144   PMID:2844223   PMID:3027058   PMID:3501295  
PMID:6294098   PMID:6323392   PMID:7509746   PMID:7521127   PMID:7525654   PMID:8148485   PMID:8148499   PMID:8381582   PMID:8384496   PMID:8471250   PMID:8536714   PMID:8589203  
PMID:8665956   PMID:8713781   PMID:8732755   PMID:8796266   PMID:9016396   PMID:9365930   PMID:9368023   PMID:9473218   PMID:9510955   PMID:9556620   PMID:10209959   PMID:10340997  
PMID:10391209   PMID:10417615   PMID:10438718   PMID:10805286   PMID:11120760   PMID:11123896   PMID:11161981   PMID:11583740   PMID:11686324   PMID:11722589   PMID:11864713   PMID:12477932  
PMID:12575940   PMID:12878585   PMID:14518028   PMID:14696115   PMID:14702039   PMID:14718574   PMID:14760718   PMID:15014966   PMID:15328353   PMID:15377716   PMID:15489334   PMID:15822942  
PMID:15853774   PMID:15878512   PMID:16169070   PMID:16335952   PMID:16344560   PMID:17258797   PMID:17332248   PMID:17450526   PMID:18184931   PMID:18193533   PMID:18362344   PMID:18974053  
PMID:19056867   PMID:19765701   PMID:19913121   PMID:20019810   PMID:20409682   PMID:20628086   PMID:21056543   PMID:21102419   PMID:21557262   PMID:21873635   PMID:21988832   PMID:22205989  
PMID:22206708   PMID:23376485   PMID:23520464   PMID:23533145   PMID:23670045   PMID:24172014   PMID:24222120   PMID:24388360   PMID:24928035   PMID:25814554   PMID:25887633   PMID:27207655  
PMID:28270177   PMID:28327460   PMID:28514442   PMID:29187436   PMID:30021884   PMID:30715578   PMID:31336797   PMID:33961781   PMID:34009669   PMID:34837923   PMID:34964303   PMID:35717024  
PMID:36000536   PMID:36177795   PMID:36244648   PMID:37327267  


Genomics

Comparative Map Data
SERPINA5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381494,581,426 - 94,593,118 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1494,561,442 - 94,593,118 (+)EnsemblGRCh38hg38GRCh38
GRCh371495,047,763 - 95,059,455 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361494,117,564 - 94,129,205 (+)NCBINCBI36Build 36hg18NCBI36
Build 341494,117,563 - 94,129,204NCBI
Celera1475,103,903 - 75,115,619 (+)NCBICelera
Cytogenetic Map14q32.13NCBI
HuRef1475,228,133 - 75,239,873 (+)NCBIHuRef
CHM1_11494,985,498 - 94,997,214 (+)NCBICHM1_1
T2T-CHM13v2.01488,811,397 - 88,823,118 (+)NCBIT2T-CHM13v2.0
Serpina5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3912104,065,572 - 104,072,397 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl12104,067,372 - 104,072,396 (+)EnsemblGRCm39 Ensembl
GRCm3812104,099,313 - 104,106,138 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl12104,101,113 - 104,106,137 (+)EnsemblGRCm38mm10GRCm38
MGSCv3712105,339,323 - 105,344,347 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3612104,502,163 - 104,507,187 (+)NCBIMGSCv36mm8
Celera12105,318,382 - 105,323,416 (+)NCBICelera
Cytogenetic Map12ENCBI
cM Map1253.3NCBI
Serpina5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86128,774,006 - 128,793,187 (+)NCBIGRCr8
mRatBN7.26123,009,224 - 123,028,412 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6123,023,306 - 123,028,407 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx6123,164,246 - 123,169,377 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06123,459,540 - 123,464,673 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06122,796,353 - 122,801,488 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.06127,753,152 - 127,772,403 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6127,766,470 - 127,772,420 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06136,972,583 - 136,990,812 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46128,156,901 - 128,161,334 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.16128,160,647 - 128,165,080 (+)NCBI
Celera6120,503,068 - 120,508,038 (+)NCBICelera
Cytogenetic Map6q32NCBI
Serpina5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543817,787,399 - 17,796,414 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543817,787,398 - 17,796,013 (-)NCBIChiLan1.0ChiLan1.0
SERPINA5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21595,729,564 - 95,742,189 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11494,946,069 - 94,958,694 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01475,205,446 - 75,217,114 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11494,537,115 - 94,548,803 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1494,537,115 - 94,548,803 (+)Ensemblpanpan1.1panPan2
SERPINA5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1863,567,060 - 63,577,015 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl863,566,356 - 63,576,308 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha863,143,801 - 63,153,748 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0863,834,133 - 63,844,074 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl863,833,699 - 63,843,370 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1863,509,369 - 63,519,317 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0863,561,712 - 63,571,667 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0863,892,389 - 63,902,350 (+)NCBIUU_Cfam_GSD_1.0
LOC101958459
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864010,883,273 - 10,897,335 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936846146,116 - 150,438 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936846141,334 - 150,381 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SERPINA5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl7115,802,150 - 115,810,824 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.17115,799,414 - 115,810,825 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.27122,916,002 - 122,927,421 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SERPINA5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12472,369,082 - 72,388,439 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2472,381,119 - 72,384,903 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605359,588,553 - 59,602,023 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Serpina5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247347,236,833 - 7,244,752 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247347,236,833 - 7,245,579 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in SERPINA5
31 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 14q32.11-32.13(chr14:90255156-95274696)x1 copy number loss See cases [RCV000051551] Chr14:90255156..95274696 [GRCh38]
Chr14:90721500..95741033 [GRCh37]
Chr14:89791253..94810786 [NCBI36]
Chr14:14q32.11-32.13		 pathogenic
GRCh38/hg38 14q24.2-32.2(chr14:72787506-99596719)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052293]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052293]|See cases [RCV000052293] Chr14:72787506..99596719 [GRCh38]
Chr14:73254214..100063056 [GRCh37]
Chr14:72323967..99132809 [NCBI36]
Chr14:14q24.2-32.2		 pathogenic
GRCh38/hg38 14q31.3-32.33(chr14:86094030-106832642)x3 copy number gain See cases [RCV000052295] Chr14:86094030..106832642 [GRCh38]
Chr14:86560374..107240869 [GRCh37]
Chr14:85630127..106311914 [NCBI36]
Chr14:14q31.3-32.33		 pathogenic
GRCh38/hg38 14q31.2-32.33(chr14:83912345-106855405)x3 copy number gain See cases [RCV000052294] Chr14:83912345..106855405 [GRCh38]
Chr14:84378689..107263620 [GRCh37]
Chr14:83448442..106334665 [NCBI36]
Chr14:14q31.2-32.33		 pathogenic
GRCh38/hg38 14q32.12-32.33(chr14:91455861-106832642)x3 copy number gain See cases [RCV000052296] Chr14:91455861..106832642 [GRCh38]
Chr14:91922205..107240869 [GRCh37]
Chr14:90991958..106311914 [NCBI36]
Chr14:14q32.12-32.33		 pathogenic
NM_000624.5(SERPINA5):c.1099G>A (p.Gly367Arg) single nucleotide variant Malignant melanoma [RCV000070677] Chr14:94592117 [GRCh38]
Chr14:95058454 [GRCh37]
Chr14:94128207 [NCBI36]
Chr14:14q32.13		 not provided
GRCh38/hg38 14q24.3-32.33(chr14:73655772-106879298)x3 copy number gain See cases [RCV000134000] Chr14:73655772..106879298 [GRCh38]
Chr14:74122475..107287505 [GRCh37]
Chr14:73192228..106358550 [NCBI36]
Chr14:14q24.3-32.33		 pathogenic
GRCh38/hg38 14q11.2-32.33(chr14:20151149-106855263)x3 copy number gain See cases [RCV000135543] Chr14:20151149..106855263 [GRCh38]
Chr14:20619308..107263478 [GRCh37]
Chr14:19689148..106334523 [NCBI36]
Chr14:14q11.2-32.33		 pathogenic
GRCh38/hg38 14q32.12-32.33(chr14:92540983-104863658)x3 copy number gain See cases [RCV000135896] Chr14:92540983..104863658 [GRCh38]
Chr14:93007328..105329995 [GRCh37]
Chr14:92077081..104401040 [NCBI36]
Chr14:14q32.12-32.33		 pathogenic
GRCh38/hg38 14q24.3-32.33(chr14:77222795-106879298)x3 copy number gain See cases [RCV000138230] Chr14:77222795..106879298 [GRCh38]
Chr14:77689138..107287505 [GRCh37]
Chr14:76758891..106358550 [NCBI36]
Chr14:14q24.3-32.33		 pathogenic
GRCh38/hg38 14q11.2-32.33(chr14:20043514-106877229)x3 copy number gain See cases [RCV000143373] Chr14:20043514..106877229 [GRCh38]
Chr14:20511673..107285437 [GRCh37]
Chr14:19581513..106356482 [NCBI36]
Chr14:14q11.2-32.33		 pathogenic
NM_000624.6(SERPINA5):c.1075G>A (p.Gly359Arg) single nucleotide variant Inborn genetic diseases [RCV003268663] Chr14:94592093 [GRCh38]
Chr14:95058430 [GRCh37]
Chr14:14q32.13		 uncertain significance
GRCh37/hg19 14q11.2-32.33(chr14:19794561-107234280)x3 copy number gain See cases [RCV000446256] Chr14:19794561..107234280 [GRCh37]
Chr14:14q11.2-32.33		 pathogenic
GRCh37/hg19 14q23.2-32.33(chr14:62493932-107285437)x3 copy number gain See cases [RCV000448557] Chr14:62493932..107285437 [GRCh37]
Chr14:14q23.2-32.33		 pathogenic
GRCh37/hg19 14q11.2-32.33(chr14:20511673-107285437) copy number gain See cases [RCV000512041] Chr14:20511673..107285437 [GRCh37]
Chr14:14q11.2-32.33		 pathogenic
GRCh37/hg19 14q32.12-32.13(chr14:93498930-96059698)x3 copy number gain See cases [RCV000511246] Chr14:93498930..96059698 [GRCh37]
Chr14:14q32.12-32.13		 uncertain significance
NM_000624.6(SERPINA5):c.406G>A (p.Asp136Asn) single nucleotide variant Inborn genetic diseases [RCV003277424] Chr14:94587768 [GRCh38]
Chr14:95054105 [GRCh37]
Chr14:14q32.13		 uncertain significance
NM_000624.6(SERPINA5):c.652A>T (p.Thr218Ser) single nucleotide variant Inborn genetic diseases [RCV003290658] Chr14:94590073 [GRCh38]
Chr14:95056410 [GRCh37]
Chr14:14q32.13		 uncertain significance
NM_000624.6(SERPINA5):c.109G>A (p.Gly37Ser) single nucleotide variant Inborn genetic diseases [RCV003248352] Chr14:94587471 [GRCh38]
Chr14:95053808 [GRCh37]
Chr14:14q32.13		 uncertain significance
GRCh37/hg19 14q24.2-32.33(chr14:73750741-107285437)x3 copy number gain See cases [RCV000512497] Chr14:73750741..107285437 [GRCh37]
Chr14:14q24.2-32.33		 pathogenic
GRCh37/hg19 14q31.2-32.2(chr14:84783137-96908198)x1 copy number loss not provided [RCV000683625] Chr14:84783137..96908198 [GRCh37]
Chr14:14q31.2-32.2		 pathogenic
GRCh37/hg19 14q11.1-32.33(chr14:19000422-107289053)x3 copy number gain not provided [RCV000738412] Chr14:19000422..107289053 [GRCh37]
Chr14:14q11.1-32.33		 pathogenic
GRCh37/hg19 14q11.2-32.33(chr14:19280733-107287663)x3 copy number gain not provided [RCV000738413] Chr14:19280733..107287663 [GRCh37]
Chr14:14q11.2-32.33		 pathogenic
GRCh37/hg19 14q11.2-32.33(chr14:19327823-107287663)x3 copy number gain not provided [RCV000738414] Chr14:19327823..107287663 [GRCh37]
Chr14:14q11.2-32.33		 pathogenic
GRCh37/hg19 14q32.13(chr14:94860687-95101343)x3 copy number gain not provided [RCV000751094] Chr14:94860687..95101343 [GRCh37]
Chr14:14q32.13		 benign
GRCh37/hg19 14q32.12-32.33(chr14:91969028-107285437)x3 copy number gain not provided [RCV000848687] Chr14:91969028..107285437 [GRCh37]
Chr14:14q32.12-32.33		 pathogenic
GRCh37/hg19 14q32.13(chr14:94859762-95099866)x3 copy number gain not provided [RCV000848224] Chr14:94859762..95099866 [GRCh37]
Chr14:14q32.13		 uncertain significance
NM_000624.6(SERPINA5):c.692T>C (p.Val231Ala) single nucleotide variant Inborn genetic diseases [RCV003273822] Chr14:94590113 [GRCh38]
Chr14:95056450 [GRCh37]
Chr14:14q32.13		 uncertain significance
NM_000624.6(SERPINA5):c.955C>T (p.Pro319Ser) single nucleotide variant Inborn genetic diseases [RCV003241515] Chr14:94590813 [GRCh38]
Chr14:95057150 [GRCh37]
Chr14:14q32.13		 uncertain significance
NM_000624.6(SERPINA5):c.1002C>T (p.Ser334=) single nucleotide variant not provided [RCV000896289] Chr14:94590860 [GRCh38]
Chr14:95057197 [GRCh37]
Chr14:14q32.13		 benign
NM_000624.6(SERPINA5):c.649G>C (p.Gly217Arg) single nucleotide variant not provided [RCV000957238] Chr14:94590070 [GRCh38]
Chr14:95056407 [GRCh37]
Chr14:14q32.13		 benign
GRCh37/hg19 14q31.2-32.2(chr14:84783523-96907490)x1 copy number loss Deletion syndrome [RCV001004048] Chr14:84783523..96907490 [GRCh37]
Chr14:14q31.2-32.2		 pathogenic
GRCh37/hg19 14q32.13(chr14:94899911-95102132)x1 copy number loss not provided [RCV001259795] Chr14:94899911..95102132 [GRCh37]
Chr14:14q32.13		 uncertain significance
GRCh37/hg19 14q32.12-32.13(chr14:94442454-95185710) copy number gain not specified [RCV002052454] Chr14:94442454..95185710 [GRCh37]
Chr14:14q32.12-32.13		 uncertain significance
GRCh37/hg19 14q32.12-32.13(chr14:94400492-96192218) copy number gain not specified [RCV002052453] Chr14:94400492..96192218 [GRCh37]
Chr14:14q32.12-32.13		 uncertain significance
NC_000014.8:g.(?_93687728)_(95560403_?)del deletion DICER1-related tumor predisposition [RCV002044285] Chr14:93687728..95560403 [GRCh37]
Chr14:14q32.12-32.13		 likely pathogenic
NC_000014.8:g.(?_90429459)_(97347545_?)dup duplication not provided [RCV003109490] Chr14:90429459..97347545 [GRCh37]
Chr14:14q32.11-32.2		 uncertain significance
GRCh37/hg19 14q13.3-32.33(chr14:37671058-106985955)x2 copy number gain See cases [RCV002286356] Chr14:37671058..106985955 [GRCh37]
Chr14:14q13.3-32.33		 pathogenic
GRCh37/hg19 14q31.2-32.33(chr14:84537502-107285437)x3 copy number gain not provided [RCV002472581] Chr14:84537502..107285437 [GRCh37]
Chr14:14q31.2-32.33		 pathogenic
NM_000624.6(SERPINA5):c.294C>A (p.Asn98Lys) single nucleotide variant Inborn genetic diseases [RCV003299983] Chr14:94587656 [GRCh38]
Chr14:95053993 [GRCh37]
Chr14:14q32.13		 uncertain significance
GRCh37/hg19 14q31.1-32.2(chr14:81593708-97059276)x3 copy number gain not provided [RCV002472541] Chr14:81593708..97059276 [GRCh37]
Chr14:14q31.1-32.2		 likely pathogenic
GRCh37/hg19 14q32.12-32.13(chr14:94637559-95522984)x3 copy number gain not provided [RCV002472422] Chr14:94637559..95522984 [GRCh37]
Chr14:14q32.12-32.13		 uncertain significance
NM_000624.6(SERPINA5):c.158A>T (p.Tyr53Phe) single nucleotide variant Inborn genetic diseases [RCV002772758] Chr14:94587520 [GRCh38]
Chr14:95053857 [GRCh37]
Chr14:14q32.13		 uncertain significance
NM_000624.6(SERPINA5):c.1213C>T (p.Arg405Cys) single nucleotide variant Inborn genetic diseases [RCV002998490] Chr14:94592231 [GRCh38]
Chr14:95058568 [GRCh37]
Chr14:14q32.13		 uncertain significance
NM_000624.6(SERPINA5):c.265A>T (p.Met89Leu) single nucleotide variant Inborn genetic diseases [RCV002952228] Chr14:94587627 [GRCh38]
Chr14:95053964 [GRCh37]
Chr14:14q32.13		 uncertain significance
NM_000624.6(SERPINA5):c.62G>A (p.Arg21His) single nucleotide variant Inborn genetic diseases [RCV002693947] Chr14:94587424 [GRCh38]
Chr14:95053761 [GRCh37]
Chr14:14q32.13		 uncertain significance
NM_000624.6(SERPINA5):c.1003G>A (p.Gly335Ser) single nucleotide variant Inborn genetic diseases [RCV002707145] Chr14:94590861 [GRCh38]
Chr14:95057198 [GRCh37]
Chr14:14q32.13		 uncertain significance
NM_000624.6(SERPINA5):c.482A>T (p.Asn161Ile) single nucleotide variant Inborn genetic diseases [RCV002830393] Chr14:94587844 [GRCh38]
Chr14:95054181 [GRCh37]
Chr14:14q32.13		 uncertain significance
NM_000624.6(SERPINA5):c.1174A>G (p.Ile392Val) single nucleotide variant Inborn genetic diseases [RCV002826674] Chr14:94592192 [GRCh38]
Chr14:95058529 [GRCh37]
Chr14:14q32.13		 uncertain significance
NM_000624.6(SERPINA5):c.742C>G (p.Arg248Gly) single nucleotide variant Inborn genetic diseases [RCV002982014] Chr14:94590163 [GRCh38]
Chr14:95056500 [GRCh37]
Chr14:14q32.13		 uncertain significance
NM_000624.6(SERPINA5):c.343C>A (p.Leu115Ile) single nucleotide variant Inborn genetic diseases [RCV002674504] Chr14:94587705 [GRCh38]
Chr14:95054042 [GRCh37]
Chr14:14q32.13		 uncertain significance
NM_000624.6(SERPINA5):c.1155C>A (p.Asn385Lys) single nucleotide variant Inborn genetic diseases [RCV002941362] Chr14:94592173 [GRCh38]
Chr14:95058510 [GRCh37]
Chr14:14q32.13		 uncertain significance
NM_000624.6(SERPINA5):c.747C>A (p.Asn249Lys) single nucleotide variant Inborn genetic diseases [RCV003176203] Chr14:94590168 [GRCh38]
Chr14:95056505 [GRCh37]
Chr14:14q32.13		 uncertain significance
NM_000624.6(SERPINA5):c.686C>T (p.Thr229Ile) single nucleotide variant Inborn genetic diseases [RCV003211037] Chr14:94590107 [GRCh38]
Chr14:95056444 [GRCh37]
Chr14:14q32.13		 uncertain significance
NM_000624.6(SERPINA5):c.932C>T (p.Ser311Phe) single nucleotide variant Inborn genetic diseases [RCV003174530] Chr14:94590790 [GRCh38]
Chr14:95057127 [GRCh37]
Chr14:14q32.13		 uncertain significance
NM_000624.6(SERPINA5):c.331T>A (p.Phe111Ile) single nucleotide variant Inborn genetic diseases [RCV003216867] Chr14:94587693 [GRCh38]
Chr14:95054030 [GRCh37]
Chr14:14q32.13		 uncertain significance
NM_000624.6(SERPINA5):c.949G>A (p.Val317Ile) single nucleotide variant Inborn genetic diseases [RCV003264578] Chr14:94590807 [GRCh38]
Chr14:95057144 [GRCh37]
Chr14:14q32.13		 likely benign
NM_000624.6(SERPINA5):c.622A>G (p.Lys208Glu) single nucleotide variant Inborn genetic diseases [RCV003348299] Chr14:94590043 [GRCh38]
Chr14:95056380 [GRCh37]
Chr14:14q32.13		 uncertain significance
NM_000624.6(SERPINA5):c.682G>C (p.Glu228Gln) single nucleotide variant not provided [RCV003393578] Chr14:94590103 [GRCh38]
Chr14:95056440 [GRCh37]
Chr14:14q32.13		 likely benign
NM_000624.6(SERPINA5):c.155T>C (p.Leu52Pro) single nucleotide variant Inborn genetic diseases [RCV003376602] Chr14:94587517 [GRCh38]
Chr14:95053854 [GRCh37]
Chr14:14q32.13		 uncertain significance
GRCh37/hg19 14q23.1-32.33(chr14:58894502-107227240)x3 copy number gain not provided [RCV003485036] Chr14:58894502..107227240 [GRCh37]
Chr14:14q23.1-32.33		 pathogenic
GRCh37/hg19 14q31.3-32.33(chr14:88580184-107285437)x3 copy number gain not provided [RCV003485051] Chr14:88580184..107285437 [GRCh37]
Chr14:14q31.3-32.33		 pathogenic
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:3464
Count of miRNA genes:903
Interacting mature miRNAs:1097
Transcripts:ENST00000329597, ENST00000553511, ENST00000553780, ENST00000554220, ENST00000554276, ENST00000554633, ENST00000554760, ENST00000554866, ENST00000555681, ENST00000556064, ENST00000556730, ENST00000556775, ENST00000557598
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
SHGC-12750  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371495,058,768 - 95,059,096UniSTSGRCh37
Build 361494,128,521 - 94,128,849RGDNCBI36
Celera1475,114,930 - 75,115,258RGD
Cytogenetic Map14q32.1UniSTS
HuRef1475,239,184 - 75,239,512UniSTS
Stanford-G3 RH Map143427.0UniSTS
GeneMap99-GB4 RH Map14252.33UniSTS
Whitehead-RH Map14333.5UniSTS
NCBI RH Map14989.2UniSTS
GeneMap99-G3 RH Map143976.0UniSTS
STS-R07994  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371495,048,544 - 95,048,724UniSTSGRCh37
Build 361494,118,297 - 94,118,477RGDNCBI36
Celera1475,104,716 - 75,104,896RGD
Cytogenetic Map14q32.1UniSTS
HuRef1475,228,971 - 75,229,151UniSTS
GeneMap99-GB4 RH Map14254.5UniSTS
NCBI RH Map141002.3UniSTS
G60289  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371495,058,710 - 95,059,051UniSTSGRCh37
Build 361494,128,463 - 94,128,804RGDNCBI36
Celera1475,114,872 - 75,115,213RGD
Cytogenetic Map14q32.1UniSTS
HuRef1475,239,126 - 75,239,467UniSTS
TNG Radiation Hybrid Map1437872.0UniSTS
GDB:212834  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371495,052,055 - 95,052,188UniSTSGRCh37
Build 361494,121,808 - 94,121,941RGDNCBI36
Celera1475,108,227 - 75,108,350RGD
Cytogenetic Map14q32.1UniSTS
HuRef1475,232,482 - 75,232,609UniSTS
GDB:217872  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371495,052,053 - 95,052,179UniSTSGRCh37
Build 361494,121,806 - 94,121,932RGDNCBI36
Celera1475,108,225 - 75,108,341RGD
Cytogenetic Map14q32.1UniSTS
SERPINA5_1304  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371495,058,662 - 95,059,446UniSTSGRCh37
Build 361494,128,415 - 94,129,199RGDNCBI36
Celera1475,114,824 - 75,115,608RGD
HuRef1475,239,078 - 75,239,862UniSTS
RH68959  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371495,058,991 - 95,059,252UniSTSGRCh37
Build 361494,128,744 - 94,129,005RGDNCBI36
Celera1475,115,153 - 75,115,414RGD
Cytogenetic Map14q32.1UniSTS
HuRef1475,239,407 - 75,239,668UniSTS
GeneMap99-GB4 RH Map14253.98UniSTS
D14S1340  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371495,059,224 - 95,059,372UniSTSGRCh37
Build 361494,128,977 - 94,129,125RGDNCBI36
Celera1475,115,386 - 75,115,534RGD
Cytogenetic Map14q32.1UniSTS
HuRef1475,239,640 - 75,239,788UniSTS
Stanford-G3 RH Map143422.0UniSTS
NCBI RH Map14987.2UniSTS
GeneMap99-G3 RH Map143971.0UniSTS
RH65034  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371495,048,845 - 95,048,948UniSTSGRCh37
Build 361494,118,598 - 94,118,701RGDNCBI36
Celera1475,105,017 - 75,105,120RGD
Cytogenetic Map14q32.1UniSTS
HuRef1475,229,272 - 75,229,375UniSTS
GeneMap99-GB4 RH Map14253.98UniSTS
NCBI RH Map141018.6UniSTS
RH70612  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371495,056,484 - 95,056,631UniSTSGRCh37
Build 361494,126,237 - 94,126,384RGDNCBI36
Celera1475,112,646 - 75,112,793RGD
Cytogenetic Map14q32.1UniSTS
HuRef1475,236,905 - 75,237,052UniSTS
GeneMap99-GB4 RH Map14253.98UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High 9 1 1 13
Medium 326 333 802 444 263 436 1169 447 605 196 761 108 10 134 963
Low 1987 1735 840 171 250 19 2977 1567 1219 138 564 1094 155 1 970 1723 2
Below cutoff 71 795 44 7 691 7 184 131 1814 62 79 255 5 100 99 2

Sequence

Nucleotide Sequences
RefSeq Transcripts NG_032908 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_000624 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF361796 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH004518 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI114432 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK096131 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK293192 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK298279 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK310869 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL049839 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL080185 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC008915 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471061 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068264 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DC394575 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HY003178 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  J02639 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M68516 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  S58545 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U35464 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000329597   ⟹   ENSP00000333203
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1494,581,426 - 94,593,118 (+)Ensembl
RefSeq Acc Id: ENST00000553511   ⟹   ENSP00000451215
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1494,581,426 - 94,587,634 (+)Ensembl
RefSeq Acc Id: ENST00000553780   ⟹   ENSP00000450837
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1494,561,442 - 94,592,796 (+)Ensembl
RefSeq Acc Id: ENST00000554220   ⟹   ENSP00000450484
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1494,561,442 - 94,587,878 (+)Ensembl
RefSeq Acc Id: ENST00000554276   ⟹   ENSP00000451610
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1494,581,615 - 94,593,115 (+)Ensembl
RefSeq Acc Id: ENST00000554633   ⟹   ENSP00000451697
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1494,581,467 - 94,587,620 (+)Ensembl
RefSeq Acc Id: ENST00000554866   ⟹   ENSP00000451126
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1494,581,394 - 94,593,115 (+)Ensembl
RefSeq Acc Id: ENST00000555681   ⟹   ENSP00000451650
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1494,581,471 - 94,587,795 (+)Ensembl
RefSeq Acc Id: ENST00000556064   ⟹   ENSP00000451487
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1494,581,971 - 94,587,435 (+)Ensembl
RefSeq Acc Id: ENST00000556730
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1494,581,391 - 94,590,767 (+)Ensembl
RefSeq Acc Id: ENST00000556775   ⟹   ENSP00000450745
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1494,581,397 - 94,590,115 (+)Ensembl
RefSeq Acc Id: ENST00000557598   ⟹   ENSP00000450485
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1494,581,880 - 94,587,833 (+)Ensembl
RefSeq Acc Id: NM_000624   ⟹   NP_000615
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381494,581,426 - 94,593,118 (+)NCBI
GRCh371495,047,706 - 95,059,457 (+)NCBI
Build 361494,117,564 - 94,129,205 (+)NCBI Archive
HuRef1475,228,133 - 75,239,873 (+)NCBI
CHM1_11494,985,498 - 94,997,214 (+)NCBI
T2T-CHM13v2.01488,811,397 - 88,823,118 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_000615   ⟸   NM_000624
- Peptide Label: preproprotein
- UniProtKB: Q07616 (UniProtKB/Swiss-Prot),   Q9UG30 (UniProtKB/Swiss-Prot),   P05154 (UniProtKB/Swiss-Prot),   B3KTV6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSP00000451650   ⟸   ENST00000555681
RefSeq Acc Id: ENSP00000451487   ⟸   ENST00000556064
RefSeq Acc Id: ENSP00000450745   ⟸   ENST00000556775
RefSeq Acc Id: ENSP00000450485   ⟸   ENST00000557598
RefSeq Acc Id: ENSP00000333203   ⟸   ENST00000329597
RefSeq Acc Id: ENSP00000450837   ⟸   ENST00000553780
RefSeq Acc Id: ENSP00000451215   ⟸   ENST00000553511
RefSeq Acc Id: ENSP00000451697   ⟸   ENST00000554633
RefSeq Acc Id: ENSP00000451126   ⟸   ENST00000554866
RefSeq Acc Id: ENSP00000451610   ⟸   ENST00000554276
RefSeq Acc Id: ENSP00000450484   ⟸   ENST00000554220
Protein Domains
SERPIN

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P05154-F1-model_v2 AlphaFold P05154 1-406 view protein structure

Promoters
RGD ID:6850870
Promoter ID:EP73230
Type:initiation region
Name:HS_SERPINA5
Description:Serine (or cysteine) proteinase inhibitor, clade A (alpha-1antiproteinase, antitrypsin), member 5.
SO ACC ID:SO:0000170
Source:EPD (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:NEDO full length human cDNA sequencing project.; Oligo-capping
Position:
Human AssemblyChrPosition (strand)Source
Build 361494,117,552 - 94,117,612EPD
RGD ID:7228521
Promoter ID:EPDNEW_H20006
Type:initiation region
Name:SERPINA5_1
Description:serpin family A member 5
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381494,581,462 - 94,581,522EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:8723 AgrOrtholog
COSMIC SERPINA5 COSMIC
Ensembl Genes ENSG00000188488 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000329597 ENTREZGENE
  ENST00000329597.12 UniProtKB/Swiss-Prot
  ENST00000553511.1 UniProtKB/TrEMBL
  ENST00000553780.5 UniProtKB/Swiss-Prot
  ENST00000554220.5 UniProtKB/TrEMBL
  ENST00000554276.1 UniProtKB/Swiss-Prot
  ENST00000554633.5 UniProtKB/TrEMBL
  ENST00000554866.5 UniProtKB/Swiss-Prot
  ENST00000555681.1 UniProtKB/TrEMBL
  ENST00000556064.1 UniProtKB/TrEMBL
  ENST00000556775.5 UniProtKB/TrEMBL
  ENST00000557598.1 UniProtKB/TrEMBL
Gene3D-CATH 2.30.39.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.30.497.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Helix hairpin bin UniProtKB/TrEMBL
  Serpins superfamily UniProtKB/TrEMBL
GTEx ENSG00000188488 GTEx
HGNC ID HGNC:8723 ENTREZGENE
Human Proteome Map SERPINA5 Human Proteome Map
InterPro Serpin_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Serpin_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Serpin_fam UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Serpin_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Serpin_sf_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Serpin_sf_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:5104 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 5104 ENTREZGENE
OMIM 601841 OMIM
PANTHER PLASMA SERINE PROTEASE INHIBITOR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR11461 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Serpin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA35505 PharmGKB
PROSITE SERPIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART SERPIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF56574 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt B3KTV6 ENTREZGENE, UniProtKB/TrEMBL
  B4DDH1_HUMAN UniProtKB/TrEMBL
  G3V264_HUMAN UniProtKB/TrEMBL
  G3V265_HUMAN UniProtKB/TrEMBL
  G3V2M1_HUMAN UniProtKB/TrEMBL
  G3V3F5_HUMAN UniProtKB/TrEMBL
  G3V3Y3_HUMAN UniProtKB/TrEMBL
  G3V482_HUMAN UniProtKB/TrEMBL
  G3V4B4_HUMAN UniProtKB/TrEMBL
  IPSP_HUMAN UniProtKB/Swiss-Prot, ENTREZGENE
  Q07616 ENTREZGENE
  Q9UG30 ENTREZGENE
UniProt Secondary Q07616 UniProtKB/Swiss-Prot
  Q9UG30 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-04-12 SERPINA5  serpin family A member 5  SERPINA5  serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5  Symbol and/or name change 5135510 APPROVED