NRBF2 (nuclear receptor binding factor 2) - Rat Genome Database

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Gene: NRBF2 (nuclear receptor binding factor 2) Homo sapiens
Analyze
Symbol: NRBF2
Name: nuclear receptor binding factor 2
RGD ID: 1346110
HGNC Page HGNC:19692
Description: Involved in autophagy. Located in cytoplasm and phosphatidylinositol 3-kinase complex, class III.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: comodulator of PPAR and RXR; comodulator of PPAR and RXR 1; comodulator of PPAR and RXR 2; COPR; COPR1; COPR2; DKFZp564C1664; FLJ30395; NRBF-2; nuclear receptor binding factor-2; nuclear receptor-binding factor 2
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Related Pseudogenes: NRBF2P1   NRBF2P2   NRBF2P3   NRBF2P4   NRBF2P5   NRBF2P6  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381063,133,328 - 63,155,024 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1063,133,247 - 63,155,031 (+)EnsemblGRCh38hg38GRCh38
GRCh371064,893,088 - 64,914,784 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361064,563,013 - 64,584,792 (+)NCBINCBI36Build 36hg18NCBI36
Build 341064,563,058 - 64,584,789NCBI
Celera1058,160,328 - 58,182,105 (+)NCBICelera
Cytogenetic Map10q21.3NCBI
HuRef1058,884,726 - 58,906,509 (+)NCBIHuRef
CHM1_11065,175,078 - 65,196,846 (+)NCBICHM1_1
T2T-CHM13v2.01063,991,431 - 64,013,145 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
3. Nuclear receptor binding factor-2 (NRBF-2), a possible gene activator protein interacting with nuclear hormone receptors. Yasumo H, etal., Biochim Biophys Acta 2000 Jan 31;1490(1-2):189-97.
Additional References at PubMed
PMID:7566098   PMID:8125298   PMID:11230166   PMID:11256614   PMID:12477932   PMID:14702039   PMID:15489334   PMID:15610520   PMID:17207965   PMID:20098747   PMID:20368287   PMID:20562859  
PMID:21653829   PMID:21873635   PMID:22001757   PMID:24026423   PMID:24785657   PMID:24823311   PMID:24849286   PMID:24999758   PMID:25086043   PMID:25416956   PMID:26073781   PMID:26186194  
PMID:26496610   PMID:26598620   PMID:26638075   PMID:27385829   PMID:27630019   PMID:28059666   PMID:28514442   PMID:28980867   PMID:29395067   PMID:29511261   PMID:29778605   PMID:31696776  
PMID:31775806   PMID:32160108   PMID:32296183   PMID:32683582   PMID:32707033   PMID:33226137   PMID:33417871   PMID:33916271   PMID:33961781   PMID:34079125   PMID:34597346   PMID:34600886  
PMID:35271311   PMID:35896951   PMID:36333468  


Genomics

Comparative Map Data
NRBF2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381063,133,328 - 63,155,024 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1063,133,247 - 63,155,031 (+)EnsemblGRCh38hg38GRCh38
GRCh371064,893,088 - 64,914,784 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361064,563,013 - 64,584,792 (+)NCBINCBI36Build 36hg18NCBI36
Build 341064,563,058 - 64,584,789NCBI
Celera1058,160,328 - 58,182,105 (+)NCBICelera
Cytogenetic Map10q21.3NCBI
HuRef1058,884,726 - 58,906,509 (+)NCBIHuRef
CHM1_11065,175,078 - 65,196,846 (+)NCBICHM1_1
T2T-CHM13v2.01063,991,431 - 64,013,145 (+)NCBIT2T-CHM13v2.0
Nrbf2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391067,102,463 - 67,121,076 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1067,102,468 - 67,121,084 (-)EnsemblGRCm39 Ensembl
GRCm381067,266,689 - 67,285,343 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1067,266,689 - 67,285,305 (-)EnsemblGRCm38mm10GRCm38
MGSCv371066,729,437 - 66,748,029 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361066,662,046 - 66,680,638 (-)NCBIMGSCv36mm8
Celera1068,358,949 - 68,377,541 (-)NCBICelera
Cytogenetic Map10B5.1NCBI
cM Map1034.89NCBI
Nrbf2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82021,307,389 - 21,325,724 (+)NCBIGRCr8
mRatBN7.22021,308,555 - 21,326,881 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2021,308,576 - 21,326,818 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2022,032,725 - 22,051,050 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02021,385,794 - 21,404,118 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02021,862,932 - 21,881,258 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02022,728,145 - 22,746,477 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2022,728,208 - 22,746,474 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02024,818,944 - 24,837,210 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42022,128,235 - 22,146,505 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12022,142,034 - 22,160,305 (+)NCBI
Celera2022,666,821 - 22,685,091 (+)NCBICelera
Cytogenetic Map20p11NCBI
Nrbf2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542516,330,114 - 16,340,621 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542516,330,115 - 16,336,798 (+)NCBIChiLan1.0ChiLan1.0
NRBF2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2875,318,097 - 75,340,092 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11075,323,454 - 75,345,415 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01059,640,101 - 59,662,071 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11061,965,758 - 61,987,435 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1061,965,758 - 61,987,435 (+)Ensemblpanpan1.1panPan2
NRBF2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1414,958,142 - 14,991,146 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl414,958,226 - 14,990,325 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha415,175,404 - 15,208,380 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0415,222,273 - 15,255,413 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl415,222,273 - 15,255,423 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1415,204,403 - 15,237,395 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0415,329,570 - 15,362,525 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0415,685,188 - 15,718,168 (+)NCBIUU_Cfam_GSD_1.0
Nrbf2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721366,078,785 - 66,097,366 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049367531,653,394 - 1,671,996 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NRBF2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1466,590,372 - 66,631,363 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11466,590,307 - 66,629,573 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21471,827,128 - 71,866,397 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NRBF2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1968,150,245 - 68,173,388 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl968,151,057 - 68,159,455 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604829,035,221 - 29,057,172 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nrbf2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624791602,274 - 620,327 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624791602,774 - 620,186 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in NRBF2
12 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 10q21.2-22.2(chr10:62229688-74468143)x1 copy number loss See cases [RCV000052530] Chr10:62229688..74468143 [GRCh38]
Chr10:63989447..76227901 [GRCh37]
Chr10:63659453..75897907 [NCBI36]
Chr10:10q21.2-22.2		 pathogenic
GRCh38/hg38 10q21.1-22.2(chr10:58436466-74415216)x1 copy number loss See cases [RCV000052511] Chr10:58436466..74415216 [GRCh38]
Chr10:60196226..76174974 [GRCh37]
Chr10:59866232..75844980 [NCBI36]
Chr10:10q21.1-22.2		 pathogenic
GRCh38/hg38 10q11.21-22.2(chr10:42685306-73715908)x3 copy number gain See cases [RCV000134848] Chr10:42685306..73715908 [GRCh38]
Chr10:43180754..75475666 [GRCh37]
Chr10:42500760..75145672 [NCBI36]
Chr10:10q11.21-22.2		 pathogenic
GRCh38/hg38 10q11.23-23.2(chr10:50729367-87147204)x3 copy number gain See cases [RCV000138007] Chr10:50729367..87147204 [GRCh38]
Chr10:52489127..88906961 [GRCh37]
Chr10:52159133..88896941 [NCBI36]
Chr10:10q11.23-23.2		 pathogenic
GRCh38/hg38 10q21.1-21.3(chr10:55287177-67558442)x3 copy number gain See cases [RCV000141179] Chr10:55287177..67558442 [GRCh38]
Chr10:57046937..69318200 [GRCh37]
Chr10:56716943..68988206 [NCBI36]
Chr10:10q21.1-21.3		 pathogenic
GRCh38/hg38 10q11.21-21.3(chr10:42112187-67400675)x3 copy number gain See cases [RCV000142967] Chr10:42112187..67400675 [GRCh38]
Chr10:42607635..69160433 [GRCh37]
Chr10:41927641..68830439 [NCBI36]
Chr10:10q11.21-21.3		 pathogenic
GRCh37/hg19 10p15.3-q26.3(chr10:93297-135378918)x3 copy number gain See cases [RCV000448750] Chr10:93297..135378918 [GRCh37]
Chr10:10p15.3-q26.3		 pathogenic
GRCh37/hg19 10p15.3-q26.3(chr10:100027-135427143) copy number gain See cases [RCV000511389] Chr10:100027..135427143 [GRCh37]
Chr10:10p15.3-q26.3		 pathogenic|uncertain significance
GRCh37/hg19 10p15.3-q26.3(chr10:100027-135427143)x3 copy number gain See cases [RCV000510861] Chr10:100027..135427143 [GRCh37]
Chr10:10p15.3-q26.3		 pathogenic
GRCh37/hg19 10q11.21-26.3(chr10:42347406-135534747)x1 copy number loss Poly (ADP-Ribose) polymerase inhibitor response [RCV000626438] Chr10:42347406..135534747 [GRCh37]
Chr10:10q11.21-26.3		 drug response
GRCh37/hg19 10p15.3-q26.3(chr10:73232-135524321)x3 copy number gain not provided [RCV000749464] Chr10:73232..135524321 [GRCh37]
Chr10:10p15.3-q26.3		 pathogenic
GRCh37/hg19 10p15.3-q26.3(chr10:98087-135477883)x3 copy number gain not provided [RCV000749465] Chr10:98087..135477883 [GRCh37]
Chr10:10p15.3-q26.3		 pathogenic
GRCh37/hg19 10q21.2-21.3(chr10:62191184-65348431)x1 copy number loss not provided [RCV001006330] Chr10:62191184..65348431 [GRCh37]
Chr10:10q21.2-21.3		 uncertain significance
GRCh37/hg19 10q11.23-21.3(chr10:50250603-69256083)x1 copy number loss not provided [RCV001006319] Chr10:50250603..69256083 [GRCh37]
Chr10:10q11.23-21.3		 pathogenic
GRCh37/hg19 10q21.1-21.3(chr10:56031210-65660398)x1 copy number loss not provided [RCV001006326] Chr10:56031210..65660398 [GRCh37]
Chr10:10q21.1-21.3		 pathogenic
NC_000010.10:g.(?_64572967)_(65225422_?)del deletion Charcot-Marie-Tooth disease, type I [RCV001874903]|Early myoclonic encephalopathy [RCV003120732] Chr10:64572967..65225422 [GRCh37]
Chr10:10q21.3		 uncertain significance
NM_030759.5(NRBF2):c.526G>A (p.Ala176Thr) single nucleotide variant Inborn genetic diseases [RCV002689384] Chr10:63153880 [GRCh38]
Chr10:64913640 [GRCh37]
Chr10:10q21.3		 uncertain significance
NM_030759.5(NRBF2):c.157G>A (p.Ala53Thr) single nucleotide variant Inborn genetic diseases [RCV002821102] Chr10:63153511 [GRCh38]
Chr10:64913271 [GRCh37]
Chr10:10q21.3		 uncertain significance
NM_030759.5(NRBF2):c.564G>C (p.Glu188Asp) single nucleotide variant Inborn genetic diseases [RCV002764345] Chr10:63153918 [GRCh38]
Chr10:64913678 [GRCh37]
Chr10:10q21.3		 uncertain significance
NM_030759.5(NRBF2):c.780T>G (p.Asn260Lys) single nucleotide variant Inborn genetic diseases [RCV002744322] Chr10:63154134 [GRCh38]
Chr10:64913894 [GRCh37]
Chr10:10q21.3		 uncertain significance
NM_030759.5(NRBF2):c.850T>A (p.Phe284Ile) single nucleotide variant Inborn genetic diseases [RCV003193168] Chr10:63154204 [GRCh38]
Chr10:64913964 [GRCh37]
Chr10:10q21.3		 uncertain significance
GRCh37/hg19 10p13-q26.3(chr10:12829206-135427143) copy number loss Distal 10q deletion syndrome [RCV003319583] Chr10:12829206..135427143 [GRCh37]
Chr10:10p13-q26.3		 pathogenic
NM_030759.5(NRBF2):c.281C>T (p.Ala94Val) single nucleotide variant Inborn genetic diseases [RCV003309655] Chr10:63153635 [GRCh38]
Chr10:64913395 [GRCh37]
Chr10:10q21.3		 likely benign
GRCh37/hg19 10p14-q26.3(chr10:11138692-135427143) copy number gain Distal trisomy 10q [RCV003319593] Chr10:11138692..135427143 [GRCh37]
Chr10:10p14-q26.3		 pathogenic
NM_030759.5(NRBF2):c.646G>A (p.Asp216Asn) single nucleotide variant Inborn genetic diseases [RCV003343453] Chr10:63154000 [GRCh38]
Chr10:64913760 [GRCh37]
Chr10:10q21.3		 uncertain significance
NM_030759.5(NRBF2):c.112G>A (p.Ala38Thr) single nucleotide variant Inborn genetic diseases [RCV003385053] Chr10:63146290 [GRCh38]
Chr10:64906050 [GRCh37]
Chr10:10q21.3		 uncertain significance
GRCh37/hg19 10q11.21-24.2(chr10:42709645-100834951)x3 copy number gain not provided [RCV003484798] Chr10:42709645..100834951 [GRCh37]
Chr10:10q11.21-24.2		 pathogenic
GRCh37/hg19 10q11.23-22.1(chr10:51735638-70791246)x1 copy number loss not provided [RCV003483092] Chr10:51735638..70791246 [GRCh37]
Chr10:10q11.23-22.1		 pathogenic
NC_000010.11:g.(?_59792917)_(68231677_?)del deletion Intellectual developmental disorder, autosomal dominant 70 [RCV003883491] Chr10:59792917..68231677 [GRCh38]
Chr10:10q21.2-21.3		 likely pathogenic
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:691
Count of miRNA genes:286
Interacting mature miRNAs:330
Transcripts:ENST00000277746, ENST00000435510
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
D3S2919E  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371064,911,907 - 64,913,385UniSTSGRCh37
GRCh37346,064,900 - 46,065,058UniSTSGRCh37
Build 36346,039,904 - 46,040,062RGDNCBI36
Celera1058,179,226 - 58,180,704UniSTS
Celera346,002,262 - 46,002,420RGD
Cytogenetic Map3pUniSTS
Cytogenetic Map10q21.3UniSTS
Cytogenetic Map3p21.3UniSTS
HuRef1058,903,627 - 58,905,107UniSTS
HuRef346,108,717 - 46,108,875UniSTS
NRBF2_9622  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371064,914,158 - 64,914,927UniSTSGRCh37
Build 361064,584,164 - 64,584,933RGDNCBI36
Celera1058,181,477 - 58,182,246RGD
HuRef1058,905,881 - 58,906,650UniSTS
D10S2278  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371064,914,501 - 64,914,752UniSTSGRCh37
Build 361064,584,507 - 64,584,758RGDNCBI36
Celera1058,181,820 - 58,182,071RGD
Cytogenetic Map10q21.3UniSTS
HuRef1058,906,224 - 58,906,475UniSTS
GeneMap99-GB4 RH Map10357.12UniSTS
Whitehead-RH Map10431.0UniSTS
Whitehead-YAC Contig Map10 UniSTS
NCBI RH Map10771.8UniSTS
RH91167  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map10q21.3UniSTS
GeneMap99-GB4 RH Map10361.19UniSTS
RH64711  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map10q21.3UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 2270 2113 1649 615 1817 456 4071 1503 2515 344 1432 1609 175 1 1202 2503 6 2
Low 169 878 77 9 134 9 286 694 1219 75 28 4 2 285
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001282405 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_030759 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006717810 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047425132 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054365680 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF267866 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK054957 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK225256 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK225257 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK301656 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL136656 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL590502 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AU310836 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY267839 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY267840 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC001345 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC011707 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471083 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068268 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DB522359 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000277746   ⟹   ENSP00000277746
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1063,133,328 - 63,155,024 (+)Ensembl
RefSeq Acc Id: ENST00000435510   ⟹   ENSP00000397502
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1063,133,247 - 63,155,031 (+)Ensembl
RefSeq Acc Id: NM_001282405   ⟹   NP_001269334
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381063,133,328 - 63,155,024 (+)NCBI
HuRef1058,884,726 - 58,906,514 (+)NCBI
CHM1_11065,175,078 - 65,196,851 (+)NCBI
T2T-CHM13v2.01063,991,431 - 64,013,145 (+)NCBI
Sequence:
RefSeq Acc Id: NM_030759   ⟹   NP_110386
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381063,133,328 - 63,155,024 (+)NCBI
GRCh371064,893,007 - 64,914,786 (+)NCBI
Build 361064,563,013 - 64,584,792 (+)NCBI Archive
Celera1058,160,328 - 58,182,105 (+)RGD
HuRef1058,884,726 - 58,906,514 (+)NCBI
CHM1_11065,175,078 - 65,196,851 (+)NCBI
T2T-CHM13v2.01063,991,431 - 64,013,145 (+)NCBI
Sequence:
RefSeq Acc Id: XM_047425132   ⟹   XP_047281088
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381063,150,228 - 63,155,024 (+)NCBI
RefSeq Acc Id: XM_054365680   ⟹   XP_054221655
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01064,008,349 - 64,013,145 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_110386   ⟸   NM_030759
- Peptide Label: isoform 1
- UniProtKB: Q9H0S9 (UniProtKB/Swiss-Prot),   Q96NP6 (UniProtKB/Swiss-Prot),   Q86UR2 (UniProtKB/Swiss-Prot),   B4DWS0 (UniProtKB/Swiss-Prot),   A6PW36 (UniProtKB/Swiss-Prot),   Q9H2I2 (UniProtKB/Swiss-Prot),   Q96F24 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001269334   ⟸   NM_001282405
- Peptide Label: isoform 2
- UniProtKB: Q96F24 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSP00000277746   ⟸   ENST00000277746
RefSeq Acc Id: ENSP00000397502   ⟸   ENST00000435510
RefSeq Acc Id: XP_047281088   ⟸   XM_047425132
- Peptide Label: isoform X1
RefSeq Acc Id: XP_054221655   ⟸   XM_054365680
- Peptide Label: isoform X1

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q96F24-F1-model_v2 AlphaFold Q96F24 1-287 view protein structure

Promoters
RGD ID:7217659
Promoter ID:EPDNEW_H14575
Type:initiation region
Name:NRBF2_1
Description:nuclear receptor binding factor 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381063,133,339 - 63,133,399EPDNEW
RGD ID:6787939
Promoter ID:HG_KWN:9742
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:ENST00000395241,   NM_030759
Position:
Human AssemblyChrPosition (strand)Source
Build 361064,562,871 - 64,563,371 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:19692 AgrOrtholog
COSMIC NRBF2 COSMIC
Ensembl Genes ENSG00000148572 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000277746 ENTREZGENE
  ENST00000277746.11 UniProtKB/Swiss-Prot
  ENST00000435510 ENTREZGENE
  ENST00000435510.6 UniProtKB/Swiss-Prot
Gene3D-CATH Phosphotransferase system, lactose/cellobiose-type IIA subunit UniProtKB/Swiss-Prot
GTEx ENSG00000148572 GTEx
HGNC ID HGNC:19692 ENTREZGENE
Human Proteome Map NRBF2 Human Proteome Map
InterPro NRBF2 UniProtKB/Swiss-Prot
  NRBF2_C UniProtKB/Swiss-Prot
  NRBF2_MIT UniProtKB/Swiss-Prot
KEGG Report hsa:29982 UniProtKB/Swiss-Prot
NCBI Gene 29982 ENTREZGENE
OMIM 616477 OMIM
PANTHER NUCLEAR RECEPTOR-BINDING FACTOR 2 UniProtKB/Swiss-Prot
  PTHR14964 UniProtKB/Swiss-Prot
Pfam NRBF2 UniProtKB/Swiss-Prot
  NRBF2_MIT UniProtKB/Swiss-Prot
PharmGKB PA134946285 PharmGKB
Superfamily-SCOP MIT domain-like UniProtKB/Swiss-Prot
UniProt A6PW36 ENTREZGENE
  B4DWS0 ENTREZGENE
  NRBF2_HUMAN UniProtKB/Swiss-Prot
  Q86UR2 ENTREZGENE
  Q96F24 ENTREZGENE
  Q96NP6 ENTREZGENE
  Q9H0S9 ENTREZGENE
  Q9H2I2 ENTREZGENE
UniProt Secondary A6PW36 UniProtKB/Swiss-Prot
  B4DWS0 UniProtKB/Swiss-Prot
  Q86UR2 UniProtKB/Swiss-Prot
  Q96NP6 UniProtKB/Swiss-Prot
  Q9H0S9 UniProtKB/Swiss-Prot
  Q9H2I2 UniProtKB/Swiss-Prot