MIR92A1 (microRNA 92a-1) - Rat Genome Database

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Gene: MIR92A1 (microRNA 92a-1) Homo sapiens
Analyze
Symbol: MIR92A1
Name: microRNA 92a-1
RGD ID: 1346101
HGNC Page HGNC:31643
Description: Enables mRNA 3'-UTR binding activity and mRNA base-pairing translational repressor activity. Involved in several processes, including cellular stress response to acid chemical; regulation of gene expression; and regulation of sprouting angiogenesis. Located in cytoplasm.
Type: ncrna (Ensembl: miRNA)
RefSeq Status: PROVISIONAL
Previously known as: C13orf25; mir-92a-1; MIR17HG; MIR92-1; MIRH1; MIRHG1; MIRN92-1; MIRN92A-1; MIRN92A1; miRNA92-1
RGD Orthologs
Mouse
Rat
Dog
Pig
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381391,351,314 - 91,351,391 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1391,351,314 - 91,351,391 (+)EnsemblGRCh38hg38GRCh38
GRCh371392,003,568 - 92,003,645 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361390,801,568 - 90,801,645 (+)NCBINCBI36Build 36hg18NCBI36
Celera1372,850,539 - 72,850,616 (+)NCBICelera
Cytogenetic Map13q31.3NCBI
HuRef1372,599,403 - 72,599,480 (+)NCBIHuRef
CHM1_11391,972,208 - 91,972,285 (+)NCBICHM1_1
T2T-CHM13v2.01390,553,890 - 90,553,967 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
B cell apoptotic process  (ISO)
blood vessel diameter maintenance  (ISS)
cellular response to amino acid stimulus  (ISO)
cellular response to fatty acid  (ISS)
cellular response to forskolin  (ISO)
cellular response to leukemia inhibitory factor  (ISO)
cellular response to low-density lipoprotein particle stimulus  (IDA)
cellular stress response to acid chemical  (IDA)
in utero embryonic development  (ISO)
long-term synaptic potentiation  (ISO)
lung development  (ISO)
miRNA-mediated gene silencing by inhibition of translation  (IDA)
miRNA-mediated post-transcriptional gene silencing  (IDA,IEA,IMP)
negative regulation of angiogenesis  (ISS)
negative regulation of apoptotic process  (ISO)
negative regulation of B cell apoptotic process  (ISO)
negative regulation of blood vessel endothelial cell migration  (IDA)
negative regulation of collagen biosynthetic process  (ISS)
negative regulation of endothelial cell proliferation  (IDA)
negative regulation of endothelial cell-matrix adhesion via fibronectin  (IDA)
negative regulation of gene expression  (IMP)
negative regulation of inflammatory response  (IMP)
negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide  (ISS)
negative regulation of JNK cascade  (ISS)
negative regulation of nitric oxide biosynthetic process  (IMP)
negative regulation of smooth muscle cell apoptotic process  (ISS)
negative regulation of sprouting angiogenesis  (IDA)
positive regulation of acute inflammatory response  (ISS)
positive regulation of apoptotic process  (ISS)
positive regulation of endothelial cell activation  (IC)
positive regulation of gene expression  (IDA,IMP)
positive regulation of inflammatory response  (ISS)
positive regulation of interleukin-6 production  (IDA)
positive regulation of leukocyte adhesion to arterial endothelial cell  (IMP)
positive regulation of leukocyte adhesion to vascular endothelial cell  (IDA,IMP)
positive regulation of monocyte chemotactic protein-1 production  (IDA)
positive regulation of programmed necrotic cell death  (ISS)
positive regulation of sprouting angiogenesis  (IDA)
pre-B cell differentiation  (ISO)
regulation of gene expression  (ISO)
regulation of heart contraction  (ISS)
sensory perception of sound  (ISO)
spinal cord motor neuron differentiation  (ISO)
vascular endothelial cell response to fluid shear stress  (IDA)
ventricular septum morphogenesis  (ISO)

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11914277   PMID:12554860   PMID:12919684   PMID:15126345   PMID:15183728   PMID:15325244   PMID:15978578   PMID:16381832   PMID:17604727   PMID:17616659   PMID:18632605   PMID:18766170  
PMID:19460962   PMID:19950226   PMID:20347265   PMID:20484043   PMID:20660482   PMID:21037258   PMID:21148309   PMID:21383985   PMID:21768538   PMID:21796614   PMID:21883694   PMID:21955497  
PMID:22153007   PMID:22267480   PMID:22563438   PMID:22617246   PMID:22895567   PMID:23308108   PMID:23355465   PMID:23499550   PMID:23622248   PMID:23625654   PMID:23681423   PMID:23820254  
PMID:23897866   PMID:23963852   PMID:24026406   PMID:24255059   PMID:24332650   PMID:24375836   PMID:24378993   PMID:24551148   PMID:24650666   PMID:24839961   PMID:24876719   PMID:24953558  
PMID:25020912   PMID:25064468   PMID:25233400   PMID:25253336   PMID:25336585   PMID:25392304   PMID:25515201   PMID:25550450   PMID:25623537   PMID:26135269   PMID:26283734   PMID:26299712  
PMID:26437339   PMID:26485305   PMID:26499948   PMID:26503628   PMID:26525353   PMID:26646931   PMID:26681654   PMID:26790436   PMID:26803387   PMID:26848774   PMID:26916216   PMID:27117818  
PMID:27246196   PMID:27491928   PMID:27523918   PMID:27565378   PMID:27596248   PMID:27629245   PMID:27791035   PMID:27801803   PMID:27806315   PMID:27884646   PMID:27993628   PMID:28069547  
PMID:28079796   PMID:28146316   PMID:28182350   PMID:28209618   PMID:28213360   PMID:28260104   PMID:28407516   PMID:28431233   PMID:28534966   PMID:28618945   PMID:28678311   PMID:28760552  
PMID:28798470   PMID:29092119   PMID:29241192   PMID:29266846   PMID:29340905   PMID:29367757   PMID:29484758   PMID:29509251   PMID:29574928   PMID:29684772   PMID:29720189   PMID:30086458  
PMID:30257711   PMID:30541951   PMID:30635407   PMID:30670045   PMID:30816508   PMID:30816526   PMID:30926679   PMID:31002156   PMID:31062357   PMID:31064356   PMID:31180538   PMID:31257524  
PMID:31346930   PMID:31378903   PMID:31456594   PMID:31500278   PMID:31558801   PMID:31591389   PMID:31696487   PMID:31841757   PMID:31863773   PMID:31870103   PMID:32075600   PMID:32131978  
PMID:32316543   PMID:32359391   PMID:32432743   PMID:32443549   PMID:32513696   PMID:32522208   PMID:32534035   PMID:32536234   PMID:32562465   PMID:32626930   PMID:32707001   PMID:32739158  
PMID:32862588   PMID:32862613   PMID:32907305   PMID:32917956   PMID:32930086   PMID:32945381   PMID:33015189   PMID:33112562   PMID:33198870   PMID:33533649   PMID:33620640   PMID:34097306  
PMID:34216514   PMID:34257272   PMID:34431444   PMID:34453780   PMID:34631883   PMID:34828265   PMID:35013491   PMID:35168644   PMID:35184640   PMID:35298438   PMID:35377980   PMID:35436050  
PMID:35484993   PMID:35536086   PMID:35546327   PMID:35614030   PMID:36178486   PMID:36214716   PMID:36254053   PMID:36269185   PMID:36601739   PMID:36639674   PMID:36735765   PMID:36811277  
PMID:36988267   PMID:37131239   PMID:37468187   PMID:37898218   PMID:38000031  


Genomics

Comparative Map Data
MIR92A1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381391,351,314 - 91,351,391 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1391,351,314 - 91,351,391 (+)EnsemblGRCh38hg38GRCh38
GRCh371392,003,568 - 92,003,645 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361390,801,568 - 90,801,645 (+)NCBINCBI36Build 36hg18NCBI36
Celera1372,850,539 - 72,850,616 (+)NCBICelera
Cytogenetic Map13q31.3NCBI
HuRef1372,599,403 - 72,599,480 (+)NCBIHuRef
CHM1_11391,972,208 - 91,972,285 (+)NCBICHM1_1
T2T-CHM13v2.01390,553,890 - 90,553,967 (+)NCBIT2T-CHM13v2.0
Mir92-1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3914115,281,859 - 115,281,938 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl14115,281,859 - 115,281,938 (+)EnsemblGRCm39 Ensembl
GRCm3814115,044,427 - 115,044,506 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl14115,044,427 - 115,044,506 (+)EnsemblGRCm38mm10GRCm38
MGSCv3714115,443,649 - 115,443,728 (+)NCBIGRCm37MGSCv37mm9NCBIm37
Celera14113,634,995 - 113,635,074 (+)NCBICelera
Cytogenetic Map14E4NCBI
cM Map1459.4NCBI
Mir92a1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81598,588,555 - 98,588,632 (+)NCBIGRCr8
mRatBN7.21592,181,336 - 92,181,413 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1592,181,336 - 92,181,413 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1596,088,125 - 96,088,202 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01597,220,991 - 97,221,068 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01594,128,397 - 94,128,474 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.015100,180,586 - 100,180,663 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl15100,180,586 - 100,180,663 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.015103,641,609 - 103,641,686 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1591,046,016 - 91,046,093 (+)NCBICelera
Cytogenetic Map15q23NCBI
MIR92A-1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12242,478,714 - 42,478,772 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2242,334,402 - 42,334,460 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02242,879,963 - 42,880,021 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.12242,562,436 - 42,562,494 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02242,616,815 - 42,616,873 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02242,617,878 - 42,617,936 (+)NCBIUU_Cfam_GSD_1.0
MIR92B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl494,624,285 - 94,624,364 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1494,624,285 - 94,624,364 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24103,407,102 - 103,407,181 (-)NCBISscrofa10.2Sscrofa10.2susScr3


Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 13q14.12-31.3(chr13:44967523-92738168)x1 copy number loss See cases [RCV000050891] Chr13:44967523..92738168 [GRCh38]
Chr13:45541658..93390421 [GRCh37]
Chr13:44439658..92188422 [NCBI36]
Chr13:13q14.12-31.3
pathogenic
GRCh38/hg38 13q22.3-32.1(chr13:78349126-94701844)x1 copy number loss See cases [RCV000051379] Chr13:78349126..94701844 [GRCh38]
Chr13:78923261..95354098 [GRCh37]
Chr13:77821262..94152099 [NCBI36]
Chr13:13q22.3-32.1
pathogenic
GRCh38/hg38 13q31.1-34(chr13:82581008-114327173)x1 copy number loss Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051380]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051380]|See cases [RCV000051380] Chr13:82581008..114327173 [GRCh38]
Chr13:83155143..115085141 [GRCh37]
Chr13:82053144..114110750 [NCBI36]
Chr13:13q31.1-34
pathogenic
GRCh38/hg38 13q31.1-32.1(chr13:83947821-95128969)x1 copy number loss See cases [RCV000051414] Chr13:83947821..95128969 [GRCh38]
Chr13:84521956..95781223 [GRCh37]
Chr13:83419957..94579224 [NCBI36]
Chr13:13q31.1-32.1
pathogenic
GRCh38/hg38 13q31.2-32.1(chr13:88260962-97285754)x1 copy number loss Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051415]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051415]|See cases [RCV000051415] Chr13:88260962..97285754 [GRCh38]
Chr13:88913217..97938008 [GRCh37]
Chr13:87711218..96736009 [NCBI36]
Chr13:13q31.2-32.1
pathogenic
GRCh38/hg38 13q31.2-32.3(chr13:88323009-98888644)x1 copy number loss See cases [RCV000051416] Chr13:88323009..98888644 [GRCh38]
Chr13:88975264..99540898 [GRCh37]
Chr13:87773265..98338899 [NCBI36]
Chr13:13q31.2-32.3
pathogenic
GRCh38/hg38 13q31.3-32.1(chr13:89549510-96657834)x1 copy number loss See cases [RCV000051417] Chr13:89549510..96657834 [GRCh38]
Chr13:90201764..97310088 [GRCh37]
Chr13:88999765..96108089 [NCBI36]
Chr13:13q31.3-32.1
pathogenic
GRCh38/hg38 13q31.1-33.2(chr13:82032938-106082542)x3 copy number gain See cases [RCV000051179] Chr13:82032938..106082542 [GRCh38]
Chr13:82607073..106734891 [GRCh37]
Chr13:81505074..105532892 [NCBI36]
Chr13:13q31.1-33.2
pathogenic
GRCh38/hg38 13q31.3(chr13:90215412-91366486)x1 copy number loss See cases [RCV000051921] Chr13:90215412..91366486 [GRCh38]
Chr13:90867666..92018740 [GRCh37]
Chr13:89665667..90816741 [NCBI36]
Chr13:13q31.3
uncertain significance
GRCh38/hg38 13q31.3(chr13:90973752-93097331)x1 copy number loss See cases [RCV000051922] Chr13:90973752..93097331 [GRCh38]
Chr13:91626006..93749584 [GRCh37]
Chr13:90424007..92547585 [NCBI36]
Chr13:13q31.3
uncertain significance
GRCh38/hg38 13q12.11-34(chr13:18946182-114304628)x3 copy number gain See cases [RCV000053726] Chr13:18946182..114304628 [GRCh38]
Chr13:19520322..115070103 [GRCh37]
Chr13:18418322..114088205 [NCBI36]
Chr13:13q12.11-34
pathogenic
GRCh38/hg38 13q12.11-34(chr13:19837395-114327173)x3 copy number gain See cases [RCV000053731] Chr13:19837395..114327173 [GRCh38]
Chr13:20411535..115085141 [GRCh37]
Chr13:19309535..114110750 [NCBI36]
Chr13:13q12.11-34
pathogenic
GRCh38/hg38 13q11-34(chr13:18565048-114327173)x3 copy number gain See cases [RCV000053719] Chr13:18565048..114327173 [GRCh38]
Chr13:19139188..115085141 [GRCh37]
Chr13:18037188..114110750 [NCBI36]
Chr13:13q11-34
pathogenic
GRCh38/hg38 13q11-34(chr13:18850545-114327173)x3 copy number gain See cases [RCV000053723] Chr13:18850545..114327173 [GRCh38]
Chr13:19296527..115085141 [GRCh37]
Chr13:18194527..114110750 [NCBI36]
Chr13:13q11-34
pathogenic
GRCh38/hg38 13q13.2-34(chr13:33528097-114327173)x3 copy number gain See cases [RCV000053759] Chr13:33528097..114327173 [GRCh38]
Chr13:34102234..115085141 [GRCh37]
Chr13:33000234..114110750 [NCBI36]
Chr13:13q13.2-34
pathogenic
GRCh38/hg38 13q14.11-34(chr13:43219125-114327314)x3 copy number gain See cases [RCV000053762] Chr13:43219125..114327314 [GRCh38]
Chr13:43793261..115085141 [GRCh37]
Chr13:42691261..114110891 [NCBI36]
Chr13:13q14.11-34
pathogenic
GRCh38/hg38 13q14.11-34(chr13:44164751-114327173)x3 copy number gain See cases [RCV000053764] Chr13:44164751..114327173 [GRCh38]
Chr13:44738887..115085141 [GRCh37]
Chr13:43636887..114110750 [NCBI36]
Chr13:13q14.11-34
pathogenic
GRCh38/hg38 13q14.12-34(chr13:44733046-114327173)x3 copy number gain See cases [RCV000053767] Chr13:44733046..114327173 [GRCh38]
Chr13:45307182..115085141 [GRCh37]
Chr13:44205182..114110750 [NCBI36]
Chr13:13q14.12-34
pathogenic
GRCh38/hg38 13q22.1-34(chr13:74345951-114327314)x3 copy number gain See cases [RCV000053770] Chr13:74345951..114327314 [GRCh38]
Chr13:74920088..115085141 [GRCh37]
Chr13:73818089..114110891 [NCBI36]
Chr13:13q22.1-34
pathogenic
GRCh38/hg38 13q31.1-34(chr13:80628584-114327173)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053772]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053772]|See cases [RCV000053772] Chr13:80628584..114327173 [GRCh38]
Chr13:81202719..115085141 [GRCh37]
Chr13:80100720..114110750 [NCBI36]
Chr13:13q31.1-34
pathogenic
GRCh37/hg19 13q31.3(chr13:90644219-92557099)x1 copy number loss See cases [RCV000234861] Chr13:90644219..92557099 [GRCh37]
Chr13:13q31.3
pathogenic
GRCh38/hg38 13q12.11-34(chr13:19833130-114298614)x3 copy number gain See cases [RCV000134104] Chr13:19833130..114298614 [GRCh38]
Chr13:20407270..115064089 [GRCh37]
Chr13:19305270..114082191 [NCBI36]
Chr13:13q12.11-34
pathogenic
GRCh38/hg38 13q11-34(chr13:18445862-114327173)x1 copy number loss See cases [RCV000135610] Chr13:18445862..114327173 [GRCh38]
Chr13:19020001..115085141 [GRCh37]
Chr13:10098739..114110750 [NCBI36]
Chr13:13q11-34
pathogenic
GRCh38/hg38 13q22.3-31.3(chr13:77061780-92460406)x1 copy number loss See cases [RCV000136886] Chr13:77061780..92460406 [GRCh38]
Chr13:77635915..93112659 [GRCh37]
Chr13:76533916..91910660 [NCBI36]
Chr13:13q22.3-31.3
pathogenic
GRCh38/hg38 13q31.2-34(chr13:88937651-114327173)x3 copy number gain See cases [RCV000137102] Chr13:88937651..114327173 [GRCh38]
Chr13:89589905..115085141 [GRCh37]
Chr13:88387906..114110750 [NCBI36]
Chr13:13q31.2-34
pathogenic
GRCh38/hg38 13q31.1-31.3(chr13:84005264-92784013)x1 copy number loss See cases [RCV000137272] Chr13:84005264..92784013 [GRCh38]
Chr13:84579399..93436266 [GRCh37]
Chr13:83477400..92234267 [NCBI36]
Chr13:13q31.1-31.3
likely pathogenic
GRCh38/hg38 13q14.11-34(chr13:40942298-114340331)x1 copy number loss See cases [RCV000137893] Chr13:40942298..114340331 [GRCh38]
Chr13:41516434..115085141 [GRCh37]
Chr13:40414434..114123908 [NCBI36]
Chr13:13q14.11-34
pathogenic
GRCh38/hg38 13q31.1-34(chr13:78999318-114327106)x3 copy number gain See cases [RCV000138742] Chr13:78999318..114327106 [GRCh38]
Chr13:79573453..115085141 [GRCh37]
Chr13:78471454..114110683 [NCBI36]
Chr13:13q31.1-34
pathogenic
GRCh38/hg38 13q31.1-34(chr13:86788927-114340331)x1 copy number loss See cases [RCV000138340] Chr13:86788927..114340331 [GRCh38]
Chr13:87441182..115085141 [GRCh37]
Chr13:86239183..114123908 [NCBI36]
Chr13:13q31.1-34
pathogenic
GRCh38/hg38 13q12.11-34(chr13:19833130-114327106)x3 copy number gain See cases [RCV000139078] Chr13:19833130..114327106 [GRCh38]
Chr13:20407270..115085141 [GRCh37]
Chr13:19305270..114110683 [NCBI36]
Chr13:13q12.11-34
pathogenic
GRCh38/hg38 13q31.2-32.3(chr13:87944479-99866542)x1 copy number loss See cases [RCV000139047] Chr13:87944479..99866542 [GRCh38]
Chr13:88596734..100518796 [GRCh37]
Chr13:87394735..99316797 [NCBI36]
Chr13:13q31.2-32.3
pathogenic
GRCh38/hg38 13q11-34(chr13:18456040-114340285)x3 copy number gain See cases [RCV000140004] Chr13:18456040..114340285 [GRCh38]
Chr13:19030180..115105760 [GRCh37]
Chr13:17928180..114123862 [NCBI36]
Chr13:13q11-34
pathogenic
GRCh38/hg38 13q31.1-34(chr13:78964223-114340331)x3 copy number gain See cases [RCV000141248] Chr13:78964223..114340331 [GRCh38]
Chr13:79538358..115085141 [GRCh37]
Chr13:78436359..114123908 [NCBI36]
Chr13:13q31.1-34
pathogenic
GRCh38/hg38 13q31.1-31.3(chr13:84052824-91838339)x3 copy number gain See cases [RCV000141994] Chr13:84052824..91838339 [GRCh38]
Chr13:84626959..92490593 [GRCh37]
Chr13:83524960..91288594 [NCBI36]
Chr13:13q31.1-31.3
uncertain significance
GRCh38/hg38 13q31.1-34(chr13:83288131-114342258)x3 copy number gain See cases [RCV000141804] Chr13:83288131..114342258 [GRCh38]
Chr13:83862266..115107733 [GRCh37]
Chr13:82760267..114125835 [NCBI36]
Chr13:13q31.1-34
pathogenic
GRCh38/hg38 13q12.11-34(chr13:19671934-114340331)x3 copy number gain See cases [RCV000142924] Chr13:19671934..114340331 [GRCh38]
Chr13:20246074..115085141 [GRCh37]
Chr13:19144074..114123908 [NCBI36]
Chr13:13q12.11-34
pathogenic
GRCh38/hg38 13q31.3(chr13:91283077-91394459)x1 copy number loss See cases [RCV000143094] Chr13:91283077..91394459 [GRCh38]
Chr13:91935331..92046713 [GRCh37]
Chr13:90733332..90844714 [NCBI36]
Chr13:13q31.3
pathogenic
GRCh38/hg38 13q31.3(chr13:91282882-91394459)x1 copy number loss See cases [RCV000143162] Chr13:91282882..91394459 [GRCh38]
Chr13:91935136..92046713 [GRCh37]
Chr13:90733137..90844714 [NCBI36]
Chr13:13q31.3
pathogenic
GRCh38/hg38 13q11-34(chr13:18862146-114342258)x3 copy number gain See cases [RCV000143462] Chr13:18862146..114342258 [GRCh38]
Chr13:19436286..115107733 [GRCh37]
Chr13:18334286..114125835 [NCBI36]
Chr13:13q11-34
pathogenic
GRCh38/hg38 13q12.11-34(chr13:19837395-114327173)x3 copy number gain See cases [RCV000148126] Chr13:19837395..114327173 [GRCh38]
Chr13:20411535..115085141 [GRCh37]
Chr13:19309535..114110750 [NCBI36]
Chr13:13q12.11-34
pathogenic
GRCh37/hg19 13q31.2-34(chr13:89796110-115083342)x1 copy number loss See cases [RCV000240161] Chr13:89796110..115083342 [GRCh37]
Chr13:13q31.2-34
pathogenic
GRCh37/hg19 13q12.11-34(chr13:19571503-115092569)x3 copy number gain See cases [RCV000240150] Chr13:19571503..115092569 [GRCh37]
Chr13:13q12.11-34
pathogenic
GRCh37/hg19 13q31.3(chr13:91209639-94704856)x3 copy number gain See cases [RCV000240035] Chr13:91209639..94704856 [GRCh37]
Chr13:13q31.3
uncertain significance
GRCh37/hg19 13q22.1-31.3(chr13:74459395-93481294)x1 copy number loss See cases [RCV000598789] Chr13:74459395..93481294 [GRCh37]
Chr13:13q22.1-31.3
pathogenic
GRCh37/hg19 13q14.3-33.3(chr13:53551300-109850651)x1 copy number loss See cases [RCV000449272] Chr13:53551300..109850651 [GRCh37]
Chr13:13q14.3-33.3
pathogenic
GRCh37/hg19 13q21.2-34(chr13:61424168-115107733)x3 copy number gain See cases [RCV000449118] Chr13:61424168..115107733 [GRCh37]
Chr13:13q21.2-34
pathogenic
GRCh37/hg19 13q12.11-34(chr13:19571503-115092510) copy number gain See cases [RCV000449142] Chr13:19571503..115092510 [GRCh37]
Chr13:13q12.11-34
pathogenic
GRCh37/hg19 13q31.1-31.3(chr13:86963003-93390362)x3 copy number gain See cases [RCV000446248] Chr13:86963003..93390362 [GRCh37]
Chr13:13q31.1-31.3
pathogenic
GRCh37/hg19 13q31.1-34(chr13:82221361-115092569)x3 copy number gain See cases [RCV000447429] Chr13:82221361..115092569 [GRCh37]
Chr13:13q31.1-34
pathogenic
GRCh37/hg19 13q21.1-34(chr13:56431743-115107733) copy number gain See cases [RCV000510722] Chr13:56431743..115107733 [GRCh37]
Chr13:13q21.1-34
pathogenic
GRCh37/hg19 13q11-34(chr13:19436286-115107733)x3 copy number gain See cases [RCV000445886] Chr13:19436286..115107733 [GRCh37]
Chr13:13q11-34
pathogenic
GRCh37/hg19 13q31.1-33.1(chr13:81851091-102864674)x1 copy number loss See cases [RCV000448988] Chr13:81851091..102864674 [GRCh37]
Chr13:13q31.1-33.1
pathogenic
GRCh37/hg19 13q31.2-34(chr13:88073140-115107733)x1 copy number loss See cases [RCV000448405] Chr13:88073140..115107733 [GRCh37]
Chr13:13q31.2-34
pathogenic
GRCh37/hg19 13q11-34(chr13:19436287-115107733) copy number gain See cases [RCV000510405] Chr13:19436287..115107733 [GRCh37]
Chr13:13q11-34
pathogenic
GRCh37/hg19 13q21.33-34(chr13:71871468-115107733)x4 copy number gain See cases [RCV000510281] Chr13:71871468..115107733 [GRCh37]
Chr13:13q21.33-34
pathogenic
GRCh37/hg19 13q31.1-34(chr13:80058840-115107733)x3 copy number gain See cases [RCV000510566] Chr13:80058840..115107733 [GRCh37]
Chr13:13q31.1-34
pathogenic
GRCh37/hg19 13q11-34(chr13:19436287-115107733)x3 copy number gain See cases [RCV000511880] Chr13:19436287..115107733 [GRCh37]
Chr13:13q11-34
pathogenic
GRCh37/hg19 13q31.1-33.3(chr13:80572498-108719528)x1 copy number loss See cases [RCV000510890] Chr13:80572498..108719528 [GRCh37]
Chr13:13q31.1-33.3
pathogenic
GRCh37/hg19 13q31.1-34(chr13:83435292-115107733)x3 copy number gain See cases [RCV000512605] Chr13:83435292..115107733 [GRCh37]
Chr13:13q31.1-34
pathogenic
GRCh37/hg19 13q14.3-32.1(chr13:53932358-96586363)x3 copy number gain See cases [RCV000512571] Chr13:53932358..96586363 [GRCh37]
Chr13:13q14.3-32.1
pathogenic
GRCh37/hg19 13q31.1-34(chr13:85176519-115107733)x3 copy number gain See cases [RCV000512242] Chr13:85176519..115107733 [GRCh37]
Chr13:13q31.1-34
pathogenic
Single allele duplication not provided [RCV000678035] Chr13:91209639..94704856 [GRCh37]
Chr13:13q31.3
likely pathogenic
GRCh37/hg19 13q22.3-34(chr13:78590089-115107733)x3 copy number gain not provided [RCV000683571] Chr13:78590089..115107733 [GRCh37]
Chr13:13q22.3-34
pathogenic
GRCh37/hg19 13q11-34(chr13:19058717-115103529)x3 copy number gain not provided [RCV000738115] Chr13:19058717..115103529 [GRCh37]
Chr13:13q11-34
pathogenic
GRCh37/hg19 13q31.1-31.3(chr13:85005334-92461147)x1 copy number loss not provided [RCV000738268] Chr13:85005334..92461147 [GRCh37]
Chr13:13q31.1-31.3
pathogenic
GRCh37/hg19 13q11-34(chr13:19031237-115107157)x3 copy number gain not provided [RCV000750643] Chr13:19031237..115107157 [GRCh37]
Chr13:13q11-34
pathogenic
GRCh37/hg19 13q21.1-31.3(chr13:57058434-94684615)x1 copy number loss not provided [RCV000750731] Chr13:57058434..94684615 [GRCh37]
Chr13:13q21.1-31.3
pathogenic
GRCh37/hg19 13q21.2-34(chr13:61775567-115107733)x3 copy number gain not provided [RCV000848025] Chr13:61775567..115107733 [GRCh37]
Chr13:13q21.2-34
pathogenic
GRCh37/hg19 13q11-34(chr13:19436286-115107733)x3 copy number gain not provided [RCV000849129] Chr13:19436286..115107733 [GRCh37]
Chr13:13q11-34
pathogenic
GRCh37/hg19 13q22.1-34(chr13:75268539-115107733)x3 copy number gain not provided [RCV002472537] Chr13:75268539..115107733 [GRCh37]
Chr13:13q22.1-34
pathogenic
GRCh37/hg19 13q14.3-34(chr13:53262013-115107733)x1 copy number loss not provided [RCV001006567] Chr13:53262013..115107733 [GRCh37]
Chr13:13q14.3-34
pathogenic
GRCh37/hg19 13q31.3(chr13:91460305-92069153)x3 copy number gain not provided [RCV001006582] Chr13:91460305..92069153 [GRCh37]
Chr13:13q31.3
likely pathogenic
GRCh37/hg19 13q31.3(chr13:91284502-92325104)x1 copy number loss See cases [RCV002285045] Chr13:91284502..92325104 [GRCh37]
Chr13:13q31.3
pathogenic
GRCh37/hg19 13p13-q34(chr13:1-115169878) copy number gain Complete trisomy 13 syndrome [RCV002280659] Chr13:1..115169878 [GRCh37]
Chr13:13p13-q34
pathogenic
GRCh37/hg19 13q11-34(chr13:19053605-115108528)x3 copy number gain See cases [RCV001353184] Chr13:19053605..115108528 [GRCh37]
Chr13:13q11-34
pathogenic
NC_000013.10:g.(?_92002837)_(103343314_?)del deletion Holoprosencephaly 5 [RCV001388033] Chr13:92002837..103343314 [GRCh37]
Chr13:13q31.3-33.1
pathogenic
GRCh37/hg19 13p13-q34(chr13:1-115169878)x3 copy number gain See cases [RCV001780076] Chr13:1..115169878 [GRCh37]
Chr13:13p13-q34
pathogenic
GRCh37/hg19 13q14.11-33.3(chr13:42504540-108206269)x3 copy number gain not provided [RCV001829235] Chr13:42504540..108206269 [GRCh37]
Chr13:13q14.11-33.3
pathogenic
GRCh37/hg19 13q11-34(chr13:19436286-115107733)x3 copy number gain not provided [RCV001834436] Chr13:19436286..115107733 [GRCh37]
Chr13:13q11-34
pathogenic
GRCh37/hg19 13q22.3-34(chr13:78514567-115107733) copy number gain not specified [RCV002053071] Chr13:78514567..115107733 [GRCh37]
Chr13:13q22.3-34
pathogenic
GRCh37/hg19 13q31.2-34(chr13:88073140-115107733) copy number loss not specified [RCV002053074] Chr13:88073140..115107733 [GRCh37]
Chr13:13q31.2-34
pathogenic
GRCh37/hg19 13q11-34(chr13:19436286-115107733) copy number gain not specified [RCV002053036] Chr13:19436286..115107733 [GRCh37]
Chr13:13q11-34
pathogenic
GRCh37/hg19 13q31.1-34(chr13:79370012-115107733) copy number loss not specified [RCV002053072] Chr13:79370012..115107733 [GRCh37]
Chr13:13q31.1-34
pathogenic
GRCh37/hg19 13q31.1-34(chr13:85037147-115107733) copy number gain not specified [RCV002053073] Chr13:85037147..115107733 [GRCh37]
Chr13:13q31.1-34
pathogenic
GRCh37/hg19 13q21.2-34(chr13:61424168-115107733) copy number gain not specified [RCV002053063] Chr13:61424168..115107733 [GRCh37]
Chr13:13q21.2-34
pathogenic
GRCh37/hg19 13q11-34(chr13:19436286-114981726) copy number gain not specified [RCV002053035] Chr13:19436286..114981726 [GRCh37]
Chr13:13q11-34
pathogenic
GRCh37/hg19 13q31.2-34(chr13:89490345-115062235)x3 copy number gain See cases [RCV002286354] Chr13:89490345..115062235 [GRCh37]
Chr13:13q31.2-34
pathogenic
GRCh37/hg19 13q11-34(chr13:19253848-115108937)x3 copy number gain not provided [RCV002291540] Chr13:19253848..115108937 [GRCh37]
Chr13:13q11-34
pathogenic
GRCh37/hg19 13q21.2-34(chr13:61534068-115107733)x3 copy number gain not provided [RCV003484899] Chr13:61534068..115107733 [GRCh37]
Chr13:13q21.2-34
pathogenic
GRCh37/hg19 13q31.1-34(chr13:82131211-115107733)x1 copy number loss not provided [RCV003483192] Chr13:82131211..115107733 [GRCh37]
Chr13:13q31.1-34
pathogenic
GRCh37/hg19 13q22.1-34(chr13:73488238-115107733)x3 copy number gain not provided [RCV003484901] Chr13:73488238..115107733 [GRCh37]
Chr13:13q22.1-34
pathogenic
GRCh37/hg19 13q21.33-33.1(chr13:73132193-104595598)x1 copy number loss not provided [RCV003483190] Chr13:73132193..104595598 [GRCh37]
Chr13:13q21.33-33.1
pathogenic
GRCh37/hg19 13q31.2-33.2(chr13:89012420-106371634)x1 copy number loss not provided [RCV003483195] Chr13:89012420..106371634 [GRCh37]
Chr13:13q31.2-33.2
pathogenic
miRNA Target Status

Confirmed Targets
Gene TargetMature miRNAMethod NameResult TypeData TypeSupport TypePMID
IQSEC1hsa-miR-92a-1-5pMirtarbaseexternal_infoCLASHFunctional MTI (Weak)23622248

Predicted Targets
Summary Value
Count of predictions:45427
Count of gene targets:16340
Count of transcripts:34561
Interacting mature miRNAs:hsa-miR-92a-1-5p
Prediction methods:Microtar, Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
RH45064  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371392,006,677 - 92,006,806UniSTSGRCh37
Build 361390,804,678 - 90,804,807RGDNCBI36
Celera1372,853,648 - 72,853,777RGD
Cytogenetic Map13q31.3UniSTS
HuRef1372,602,512 - 72,602,641UniSTS
GeneMap99-GB4 RH Map13255.96UniSTS
NCBI RH Map13798.9UniSTS
G59670  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371392,006,677 - 92,006,802UniSTSGRCh37
Build 361390,804,678 - 90,804,803RGDNCBI36
Celera1372,853,648 - 72,853,773RGD
Cytogenetic Map13q31.3UniSTS
HuRef1372,602,512 - 72,602,637UniSTS


Expression


Sequence


RefSeq Acc Id: ENST00000385233
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1391,351,314 - 91,351,391 (+)Ensembl
RefSeq Acc Id: NR_029508
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381391,351,314 - 91,351,391 (+)NCBI
GRCh371392,003,568 - 92,003,645 (+)RGD
Celera1372,850,539 - 72,850,616 (+)RGD
HuRef1372,599,403 - 72,599,480 (+)ENTREZGENE
CHM1_11391,972,208 - 91,972,285 (+)NCBI
T2T-CHM13v2.01390,553,890 - 90,553,967 (+)NCBI
Sequence:

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:31643 AgrOrtholog
COSMIC MIR92A1 COSMIC
Ensembl Genes ENSG00000283705 Ensembl, ENTREZGENE
Ensembl Transcript ENST00000385233 ENTREZGENE
GTEx ENSG00000283705 GTEx
HGNC ID HGNC:31643 ENTREZGENE
Human Proteome Map MIR92A1 Human Proteome Map
miRBase MI0000093 ENTREZGENE
NCBI Gene 407048 ENTREZGENE
OMIM 609422 OMIM
PharmGKB PA164723002 PharmGKB
RNAcentral URS00001DA458 RNACentral
  URS00002B6637 RNACentral
  URS00003768C5 RNACentral