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Gene: MRTFB (myocardin related transcription factor B) Homo sapiens
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Symbol: MRTFB
Name: myocardin related transcription factor B
RGD ID: 1345947
Description: Exhibits transcription coactivator activity. Involved in positive regulation of striated muscle tissue development and positive regulation of transcription by RNA polymerase II. Predicted to localize to cytoplasm and nucleus; INTERACTS WITH (-)-epigallocatechin 3-gallate; 3-Chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone; 3-methylcholanthrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: CTA-276F8.1; DKFZp686J1745; FLJ31823; FLJ45623; megakaryoblastic leukemia 2; MKL and myocardin family member 2; MKL/myocardin like 2; MKL/myocardin-like 2; MKL/myocardin-like protein 2; MKL1/myocardin like 2; MKL2; MRTF-B; myocardin-related transcription factor B; NPD001
Orthologs:
Mus musculus (house mouse) : Mrtfb (myocardin related transcription factor B)  MGI  Alliance
Rattus norvegicus (Norway rat) : Mrtfb (myocardin related transcription factor B)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mrtfb (myocardin related transcription factor B)
Pan paniscus (bonobo/pygmy chimpanzee) : MRTFB (myocardin related transcription factor B)
Canis lupus familiaris (dog) : MRTFB (myocardin related transcription factor B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mrtfb (myocardin related transcription factor B)
Sus scrofa (pig) : MRTFB (myocardin related transcription factor B)
Chlorocebus sabaeus (African green monkey) : MRTFB (myocardin related transcription factor B)
Heterocephalus glaber (naked mole-rat) : Mrtfb (myocardin related transcription factor B)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1614,071,321 - 14,266,773 (+)EnsemblGRCh38hg38GRCh38
GRCh38.p13 Ensembl1614,071,319 - 14,266,773 (+)EnsemblGRCh38hg38GRCh38
GRCh381614,071,062 - 14,266,779 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371614,165,178 - 14,360,633 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361614,072,697 - 14,268,131 (+)NCBINCBI36hg18NCBI36
Build 341614,072,696 - 14,268,130NCBI
Celera1614,340,460 - 14,536,766 (+)NCBI
Cytogenetic Map16p13.12NCBI
HuRef1614,082,327 - 14,277,730 (+)NCBIHuRef
CHM1_11614,165,118 - 14,360,620 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on MRTFB
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1345947
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-10-06
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.