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Gene: IKZF1 (IKAROS family zinc finger 1) Homo sapiens
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Symbol: IKZF1
Name: IKAROS family zinc finger 1
Description: Exhibits DNA binding activity and protein domain specific binding activity. Involved in erythrocyte differentiation; lymphocyte differentiation; and protein heterooligomerization. Localizes to the nuclear pericentric heterochromatin and protein-containing complex. Implicated in common variable immunodeficiency and precursor B lymphoblastic lymphoma/leukemia.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CLL-associated antigen KW-6; CVID13; DNA-binding protein Ikaros; hIk-1; Hs.54452; IK1; IKAROS; Ikaros (zinc finger protein); IKAROS family zinc finger 1 (Ikaros); ikaros family zinc finger protein 1; LyF-1; LYF1; lymphoid transcription factor LyF-1; PPP1R92; PRO0758; zinc finger protein, subfamily 1A, 1 (Ikaros); ZNFN1A1
Orthologs:
Mus musculus (house mouse) : Ikzf1 (IKAROS family zinc finger 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ikzf1 (IKAROS family zinc finger 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ikzf1 (IKAROS family zinc finger 1)
Pan paniscus (bonobo/pygmy chimpanzee) : IKZF1 (IKAROS family zinc finger 1)
Canis lupus familiaris (dog) : IKZF1 (IKAROS family zinc finger 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ikzf1 (IKAROS family zinc finger 1)
Sus scrofa (pig) : IKZF1 (IKAROS family zinc finger 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl750,304,068 - 50,405,101 (+)Ensembl
GRCh38750,303,453 - 50,405,101 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37750,344,378 - 50,367,358 (+)NCBIGRCh37GRCh37hg19GRCh37
GRCh37750,444,231 - 50,472,799 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36750,411,725 - 50,440,293 (+)NCBINCBI36hg18NCBI36
Build 34750,218,438 - 50,244,768NCBI
Celera750,439,276 - 50,537,765 (+)NCBI
Cytogenetic Map7p12.2NCBI
HuRef750,224,730 - 50,247,709 (+)NCBIHuRef
HuRef750,294,198 - 50,322,765 (+)NCBIHuRef
CHM1_1750,345,970 - 50,475,092 (+)NCBICHM1_1
CRA_TCAGchr7v2750,381,631 - 50,478,870 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
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Disease Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on IKZF1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1345718
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.