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Gene: H1-4 (H1.4 linker histone, cluster member) Homo sapiens
Symbol: H1-4
Name: H1.4 linker histone, cluster member
Description: Exhibits chromatin DNA binding activity. Predicted to be involved in DNA packaging and regulation of nucleobase-containing compound metabolic process. Localizes to the nuclear heterochromatin.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: dJ221C16.5; H1 histone family, member 4; H1.4; H1E; H1F4; H1s-4; HIST1H1E; histone 1, H1e; histone cluster 1 H1 family member e; histone cluster 1, H1e; histone H1.4; histone H1b; histone H1s-4; MGC116819; RMNS
Mus musculus (house mouse) : H1f4 (H1.4 linker histone, cluster member)  MGI  Alliance
Rattus norvegicus (Norway rat) : H1f4 (H1.4 linker histone, cluster member)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : H1-4 (H1.4 linker histone, cluster member)
Pan paniscus (bonobo/pygmy chimpanzee) : H1-4 (H1.4 linker histone, cluster member)
Canis lupus familiaris (dog) : LOC488269 (histone H1.4)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl626,156,354 - 26,157,107 (+)Ensembl
GRCh38626,156,329 - 26,157,115 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37626,156,559 - 26,157,343 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36626,264,538 - 26,265,322 (+)NCBINCBI36hg18NCBI36
Build 34626,264,537 - 26,265,322NCBI
Celera627,385,861 - 27,386,645 (+)NCBI
Cytogenetic Map6p22.2NCBI
HuRef626,099,532 - 26,100,316 (+)NCBIHuRef
CHM1_1626,158,764 - 26,159,548 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on H1-4
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1345558
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-01-07
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.