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Gene: GDF3 (growth differentiation factor 3) Homo sapiens
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Symbol: GDF3
Name: growth differentiation factor 3
RGD ID: 1345464
Description: Exhibits protein kinase binding activity. Involved in several processes, including negative regulation of BMP signaling pathway; negative regulation of epidermal cell differentiation; and skeletal system development. Localizes to cytoplasm. Implicated in Klippel-Feil syndrome 3 and isolated microphthalmia 7.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: GDF-3; growth/differentiation factor 3; KFS3; MCOP7; MCOPCB6
Orthologs:
Mus musculus (house mouse) : Gdf3 (growth differentiation factor 3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Gdf3 (growth differentiation factor 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gdf3 (growth differentiation factor 3)
Pan paniscus (bonobo/pygmy chimpanzee) : GDF3 (growth differentiation factor 3)
Canis lupus familiaris (dog) : GDF3 (growth differentiation factor 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gdf3 (growth differentiation factor 3)
Sus scrofa (pig) : GDF3 (growth differentiation factor 3)
Chlorocebus sabaeus (African green monkey) : GDF3 (growth differentiation factor 3)
Heterocephalus glaber (naked mole-rat) : Gdf3 (growth differentiation factor 3)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl127,689,784 - 7,695,775 (-)EnsemblGRCh38hg38GRCh38
GRCh38127,689,784 - 7,695,775 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37127,842,381 - 7,848,360 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36127,733,648 - 7,739,627 (-)NCBINCBI36hg18NCBI36
Build 34127,733,647 - 7,739,627NCBI
Celera129,419,392 - 9,425,368 (-)NCBI
Cytogenetic Map12p13.31NCBI
HuRef127,656,489 - 7,662,465 (-)NCBIHuRef
CHM1_1127,839,618 - 7,847,334 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
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Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on GDF3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1345464
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-09-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.